I feel like Makka can only be with Soul because in Soul Eater it seems that each person is put with the one person who will always understand them. I mean even Black Star and Suabaki have that connection. So I have to say no I don't think it would work.
@Msfancysunshine I can agree with you there, kind of. I believe that in soul eater they are put with someone who understands them, but I don't believe that it has to be a romantic way. I believe maka can be romantically involved with others. In fact I think a meister and their weapon shouldn't be romantically involved, because it would complicate things