MONKEY D. LUFFY ALL THE WAY!!
Luffy wins on this one because he ends up fighting and fighting until he is literally and completely exhausted to protect his nakama. As a captain, he know when his nakama can fight alongside him, and when he knows that they can't he tells them to run and he is the one to take on the excruciating pain that is to come from the enemy that they are facing/ trying to run from. So my vote goes to Luffy.