Ace's death was probably the only time I've legitimately cried during an anime. I teared up when L died, when they burned the Merry, watched through all the sick shit that happened to Naruto, and everything else. But I can honestly say that I had big girl tears with this one. And I don't think it was Ace's death, I think it was Luffy's reaction to it. The way he screamed his brother's name just made me break down. The end.