Manufacturing just fifty grams of meth in China will earn you a death sentence. Timmy Choi (Louis Koo) has manufactured tons, and after a violent lab accident, he's in the custody of Captain Zhang (Sun Honglei). Now, he has only one chance to avoid execution: turn informant and help Zhang’s undercover team take down the powerful cartel he’s been cooking for. But as the uneasy allies are forced to compress months of police work into just 72 sleepless hours, the increasingly desperate police are quickly stretched past their limits. As things spin wildly out of control, the line between duty and recklessness is blurred, and it becomes unclear whether Zhang or Choi actually has the upper hand.