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Hoodia Benefits, Side Effects & Dosage

What is Hoodia?

Hoodia, or Hoodia gordonii, is a spiny, leafless, succulent plant that grows in the Kalahari Desert region of Africa near Botswana. Hoodia contains an active molecule that seems to restrain the brain’s hunger trigger. This property makes hoodia an excellent option for an appetite suppressant and anti-obesity supplement. Though there are challenges in harvesting hoodia, and research is still ongoing, the potential beneficial properties of hoodia are now available in supplement form.

Hoodia History

Nicknamed Bushman’s Hat by some and called “Xhoba” by the locals, hoodia came to the attention of a Dutch anthropologist in 1937. He was studying the nomadic San Bushmen of the Kalahari Desert. It was their tradition to bring some hoodia plant along on a long hunting trip. The tribesmen would suck on fresh or dried hoodia to fight hunger pangs and thirst on their travels through sparse desert areas. The plant was also used during times of famine.

Hoodia and Science

The first organized study of Hoodia wasn’t initiated until 1963 when South African scientists from the Council for Scientific and Industrial Research (CSIR) conducted trials with lab animals and found that participants given hoodia lost weight.

In the 1990s, Phytopharm, a British pharmaceutical company, began serious research on hoodia to determine what made it work. They isolated the active molecule in this desert plant and called it P57. There are other species of hoodia plants, but only Hoodia gordonii contains the appetite-suppressing molecule P57. After spending $20 million on research, Phytopharm patented P57.  Phytopharm then began working with Unilever to produce hoodia on a larger scale, using hoodia plantations located in South Africa. There are, however, a few problems with mass-producing hoodia:
The plant requires extremely high temperatures to flourish
It grows only one or two inches per year
It takes four to five years to mature
Despite the challenges in producing larger quantities of hoodia, CSIR signed a benefit-sharing agreement with the San people for using the native hoodia that grows in their backyard. As part of the agreement, the CSIR has agreed to give the San people a share of royalties from the sale of the patented extract.

Hoodia and the Hypothalamus

Curbing your appetite is not just purely psychological. In other words, it’s not all about willpower and denial. There are physical factors beyond your control that are going on behind the scenes. Thankfully, hoodia can help with this. But how?
First of all, it’s important to understand how the brain processes hunger. There’s involuntary magic going on inside your brain, coordinated by the powerful and mysterious organ known as the hypothalamus. The hypothalamus handles things like emotional responses, puberty prompts, hunger cues and endorphin triggers.
The desire to eat is influenced by a complex group of chemicals
Picture the hypothalamus as an orchestra director, waving his hand to ask for slightly more chemical uptake here and a little less there. A beautiful balance results when the body does its job, and we would be wise to listen to the signals our body is giving us. In addition to the inner chemical overture, the sight and smell of food can provoke the desire to eat, which can lead to unhealthy eating habits.
Smart Chemicals: Ghrelin & Leptin
When foods break down into usable chemicals:
Protein is metabolized into amino acids
Fatty acids are derived from fats we eat
Glucose is metabolized from carbohydrates
These food-derived chemicals regulate hormones like insulin.
If more food is needed, the hormones send messages to the brain. Neurotransmitters (NPY) act as messengers that communicate with smart chemicals like ghrelin and leptin. If blood sugar (glucose) is low, the body responds through a surge of ghrelin and more NPY activity in the hypothalamus. We begin to crave sweet and starchy foods when NPY is stimulated. The spike in ghrelin creates a rise in appetite.
While you are sleeping, you aren’t ingesting any food, so your blood sugar levels dwindle. This decrease causes your brain to release NPY. If you skip breakfast, this influx of NPY can set you up, unaware, for a sugar binge in the afternoon. You can tell yourself to skip the candy bar, but your body’s inner signals will prompt you to eat it.
On the other side, we have leptin. Leptin’s job is to tell the body you’ve had enough. Leptin spikes after eating and restrains NPY from sending more hunger messages. Ghrelin and leptin ride the seesaw — when blood sugar is low, leptin is low and ghrelin is high; when you feel full, leptin is high and ghrelin is low.

Smart Chemicals: Galanin & CCK
Brain chemicals are associated with appetite. Galanin is a fat-sensing chemical, and it spikes when we need more fat. Galanin levels rise in the evening when our bodies need fat and calories to get us through the night.
CCK (cholecystokinin), on the other hand, senses that food is in the stomach. CCK turns off the appetite. When a person eats large quantities too quickly, it may not give enough time for CCK to work. Findings show that in cases of anorexia or bulimia, CCK is not working properly or has been desensitized.
Hoodia’s P57 Mimics Glucose
Glucose (blood sugar) is the fuel that runs the body’s cells. Its high or low levels cause the body to react and send smart chemicals to the rescue. The hypothalamus works to make sure the blood sugar is flowing at appropriate levels and sends appropriate messages. G-protein receptors work in coordination with the hypothalamus. They match up with glucose molecules and bind with them. When they find and bind with glucose, they tell the body there’s an adequate level of glucose — no need to eat more.

The receptors don’t bind with just any molecule — they only fit with glucose. But that’s the amazing thing about hoodia’s active molecule, P57. It fits the receptor. To the body, it looks like and fits like a glucose molecule.  So, when P57 binds to the receptor, it fools the body into thinking there’s enough glucose. Thus, the person does not sense the need to eat. In fact, P57 binds stronger and longer to the receptors than a true glucose molecule and is many times more active than glucose.

Hoodia Testing

It is important to realize that scientific testing of hoodia has been limited. In a study conducted on rats, subjects ate less after being injected with hoodia. Phytopharm also conducted a clinical trial with eighteen human volunteers. The results showed that hoodia consumption reduced intake by an average of 1,000 calories per day in the subjects. To clarify, hoodia may be an adjunct to weight control when used with caloric restriction and an active, healthy lifestyle.

Hoodia and Weight Loss

The simple, practical summary of how hoodia helps you lose weight:
Hoodia makes you less hungry
Hoodia can prevent you from overeating
When you are less hungry, you have time to make healthy food choices
If you want to try hoodia for appetite suppression and you can’t travel to the Kalahari desert to break off a chunk for yourself, there are other options available. You can buy Hoodia gordonii supplements in various forms, including hoodia capsules and hoodia powder.
Hoodia is an ingredient in some diet pills. Other names for hoodia are xhooba, ghaap, South African desert cactus and hoodia cactus.

Hoodia Cautions and Side Effects

Unfortunately, there are products claiming to contain pure Hoodia gordonii that do not contain it — look for genuine South African hoodia
Hoodia may suppress thirst as well as hunger; to prevent dehydration, you should consume 64 ounces of water each day
The American Botanical Council, a non-profit research organization, has not received reports of any negative effects of those taking hoodia
Children, pregnant or nursing mothers should not take hoodia
Do not take hoodia if you are taking prescription medications without speaking to a doctor first.

Hoodia Dosage

Taken as a dietary supplement, 250 mg to 500 mg of hoodia should be taken before meals or as directed by your physician. Be sure to follow the package guidelines and discuss taking it with your health practitioner.

The Bottom Line

One of the most common stumbling blocks to weight loss is overconsumption. However, an appetite suppressant like hoodia in combination with a balanced diet and exercise program may force your body to use the fat and energy it has stored to promote weight loss. Hoodia has a strong history of use as an appetite suppressant. Hoodia gordonii is currently available in different forms to the public, though more research is necessary by the scientific and medical communities.
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DelveInsight's "Becker Muscular Dystrophy Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of the Becker Muscular Dystrophy (BMD), historical and forecasted epidemiology as well as the Becker Muscular Dystrophy (BMD) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. Becker Muscular Dystrophy (BMD) is an inherited muscle structure disorder that results in progressive deterioration of limbs, cardiac and skeletal muscles. However, the involuntary muscles are not affected. BMD is milder version of Duchenne Muscular Dystrophy (DMD). BMD usually begins in the teens or early adulthood, and the course is slower and far less predictable than that of DMD. Some facts of Becker Muscular Dystrophy Market are: · According to the Genetic and Rare Diseases Information Center, the prevalence of BMD is estimated to be between 17–27 cases per million people. This means that at a given time,about one in 37,000 to one in 59,000 people are living with BMD. · According to the Centers for Disease Control and Prevention (CDC), the estimated prevalence of Duchenne and Becker muscular dystrophy (DBMD) was one in every 7,250 males aged 5–24 years. However, the prevalence of DMD was found to be three times higher than the prevalence of BMD. · Through several studies, it can be estimated that the occurrence of BMD varies from one per 18,000 to one per 31,000 male births. · According to a study conducted by Walter et al. titled “Recent developments in Duchenne muscular dystrophy: facts and numbers”, the worldwide prevalence of BMD is estimated to be 1.53 per 100,000 males and according to recent calculations of the German population, about 600 BMD patients are supposed to live in Germany. Request for Sample Pages: https://www.delveinsight.com/report-store/becker-muscular-dystrophy-market Scope of the Becker Muscular Dystrophy Market Report · The report covers the descriptive overview of Becker Muscular Dystrophy (BMD), explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies · Comprehensive insight has been provided into the Becker Muscular Dystrophy (BMD) epidemiology and treatment in the 7MM · Additionally, an all-inclusive account of both the current and emerging therapies for Becker Muscular Dystrophy (BMD) is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape · A detailed review of the Becker Muscular Dystrophy (BMD) market; historical and forecasted is included in the report, covering drug outreach in the 7MM · The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Becker Muscular Dystrophy (BMD) market Some Becker Muscular Dystrophy Companies are: · PTC Therapeutics · Italfarmaco · Epirium Bio · Edgewise Therapeutics · And Many Others Request for Sample Pages: https://www.delveinsight.com/report-store/becker-muscular-dystrophy-market Becker Muscular Dystrophy Drugs · Translarna · Givinostat · EPM-01 · EDG-5506 · And Many Others Table of Content: 1. Key Insights 2. Executive Summary of Becker Muscular Dystrophy (BMD) 3. Competitive Intelligence Analysis for Becker Muscular Dystrophy (BMD) 4. Becker Muscular Dystrophy (BMD): Market Overview at a Glance 5. Becker Muscular Dystrophy (BMD): Disease Background and Overview 6. Patient Journey 7. Becker Muscular Dystrophy (BMD) Epidemiology and Patient Population 8. Treatment Algorithm, Current Treatment, and Medical Practices 9. Becker Muscular Dystrophy (BMD) Unmet Needs 10. Key Endpoints of Becker Muscular Dystrophy (BMD) Treatment 11. Becker Muscular Dystrophy (BMD) Marketed Products 12. Becker Muscular Dystrophy (BMD) Emerging Therapies List to be continued in report 13. Becker Muscular Dystrophy (BMD): Seven Major Market Analysis 14. Attribute analysis 15. 7MM: Market Outlook 16. Access and Reimbursement Overview of Becker Muscular Dystrophy (BMD) 17. KOL Views 18. Market Drivers 19. Market Barriers 20. Appendix 21. DelveInsight Capabilities 22. Disclaimer
How much are the candles with the rings in them?
Experience the excitement of uncovering a beautiful piece of sterling silver jewelry from within each of our handcrafted products. You can rest assured that you are getting high-quality, earth-friendly products! Each candle is a soy wax blend that is hand-poured into a reusable jar with a cotton wick or wood wick. Every bath bomb has moisturizing coconut and apricot kernel oil-infused to leave your skin feeling silky soft. All of our Body Products are plant-based and ready to benefit your skin! Jewel Within is the best gift to give as it's fun to give and exciting to receive. Uncover your surprise! 100% Natural Wax; Coconut + Soy candles are known to calm the nerves and relieve anxiety. Our organic scented candle's uniquely blended fragrance soothes you after a long and tiring day. We hand-pour all our products; a process that sets us apart from our competitors and ensures a delicate finish and the highest quality result.  Green bamboo balances grapefruit, violet petals, and green accord with a subtle base of soft musk for a finish as crisp as the calm air after a cleansing sunshower.  A heavenly meadow- this calming scent blended with notes of lavender, Sicilian lemon, and clary sage evokes a peaceful stroll among the purple fields.    Candles with Rings Inside are becoming increasingly popular due to the lovely bonus of finding a ring in your candle. But which are the best ring candles? We’ve reviewed 5 of the best ring candles, that not only provide a variety of different rings and jewelry to choose from. But that also offers delightful scents and fragrances. One of the reasons ring candles are popular is that often you don’t know which specific ring or piece of jewelry you’ll get, so it’s a nice surprise to discover which you have found. This variety appeals to many, however, sometimes the variety might be too much for some and you might find a ring or piece of jewelry you don’t like. There are some ring candle manufacturers that may provide a random ring from a variety, but all these rings will be a similar style and not vary in appearance too much. So bear this in mind when you’re making your ring choices. Often people will forget to make sure that their jewelry candle actually has a ring that fits their finger. Most will have a good range of sizes for most people’s fingers, however, some have more choice of ring size than others. So make sure you buy a ring of the candle a ring the right size that actually can fit your finger! When you’re considering the scent of your candle, bear in mind not only the name on the label but also accompanying fragrances as these can have a big impact. You also want to bear in mind the scent throw of the candle (e.g. how well the candle ‘throw’s off iits scent/how strong the scent is when burning), as people have different preferences for how strong they want their candles to smell.
Rex Ryan Loses Weight Big Time Two Years after his Lap Band Surgery
After two years from his lap band surgery, Rex Ryan shares happy news of losing weight over two years. How did a lap band surgery help him lose weight steadily? Here’s a look at how a lap band procedure is done. The bubbling and talkative Rex Ryan, coach for the New York Jets is now happy with her weight loss more than ever. Although it has been already a couple of years since his lap band surgery, he is more open to talking about it now. Now that it has proved to be effective and has helped him lose 106 pounds. How did a Lap Band Surgery Helped Rex Ryan Lose Weight? Lap band surgery, which is also called Laparoscopic adjustable gastric banding or adjustable gastric banding surgery is a kind of surgical procedure that effectively makes your stomach smaller. When you are overweight or obese your stomach’s capacity to take in food becomes bigger, so when you eat; it takes more food consumption for you to have that feeling of fullness. After a lap band surgery, you will feel full after eating fewer amounts of food or drinks, since your stomach can only hold so much. Contrary to what you may think, your surgeon will only make small incisions for a camera and tools to go through your stomach. With the aid of the camera, your doctor will then place a band or a ring on the upper part of your stomach. A small tube is attached to that ring, and that tube has a port that your surgeon under the skin can access. That port is where your surgeon will make the necessary adjustments in the following 4 to 6 weeks after the surgery. The band placed around your stomach is not immediately tightened during the surgery. Your surgeon will add some saline in that tube to tighten the band and siphon saline there if the band needs to be loosened. Weight loss with lap band surgery is a slow but steady journey to successful weight loss. Pain relievers will be on top of your list to help you cope with any discomfort and aches after the surgery. For the first couple of weeks after the surgery, you are actually encouraged to move around and about slowly to help you heal faster. You also need to have a steady supply of water in your system, so sipping water throughout the day is very important. Just sipping so as not to shock your stomach. Your diet will also be mostly liquid and soft, and in time, you can eventually incorporate solid food in your diet. You will benefit a lot by having a nutritionist or dieticians helping you plan your diet right after surgery. You will lose weight, but remember that you need proper nutrients to really make this surgery a successful one. Your surgeon will add saline solution within the first year to make your stomach smaller. Now this needs to be done with proper balance, because your stomach should just be in the right size – so you don’t throw up at all. And tightening this band will help reduce your stomach’s capacity, as well as the amount of time your food gets processed in your digestive system. Rex Ryan’s Lap Band procedure was a success. This kind of surgery does not help remove any adipose tissue, but helps you eat less; thus helping you lose weight steadily. However, the lap band surgery is not for everyone, there is a certain criteria’s that need to be met before getting an approval from your doctor.