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Rheumatoid Arthritis: Symptoms, Risk Factors & Treatment

What is Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is one type of arthritis and it is a persistent inflammatory joint condition. RA is an autoimmune disease, which means the immune system misinterprets the joint linings for “foreign” objects, so it attacks and destroys them. This leads to inflammation and pain.
Around 1.3 million people in the U.S. live with rheumatoid arthritis. In fact, a 2017 report shows that between 2004 and 2014, the condition increased significantly in the U.S., affecting around 1.36 million people in 2014. According to the Arthritis Foundation, women are 70 percent more likely to develop rheumatoid arthritis.
The most common symptom of rheumatoid arthritis is stiff joints, particularly after sitting down for a long time or upon waking up in the morning. Some individuals also often feel sick or fatigued and they may have a fever or loss of appetite.
Researchers have not discovered a specific cause for rheumatoid arthritis, but genes, hormones and environment can contribute. Treatment options include lifestyle changes, medication and surgery. These may stop or slow joint damage, as well as reduce swelling and pain.
Rheumatoid Arthritis vs. Osteoarthritis
Rheumatoid arthritis is different from osteoarthritis because it is an autoimmune disease, while osteoarthritis is progressive. RA develops from an overactive immune system that targets the joints and causes inflammation. The symptoms often appear quickly and worsen within a short amount of time. On the other hand, osteoarthritis is progressive, meaning it causes damage to the joints over time. It is caused by wear and tear on the joints and the symptoms usually only affect individual joints.

Symptoms of Rheumatoid Arthritis

RA symptoms can affect several different parts of the body and gradually wears away the bone. Although it may affect several different joints, they usually affect the hands (specifically the fingers and knuckles), wrists, shoulders, elbows, toes, knees, ankles and hips.
Joint Pain & Tenderness
Pain is an early defining symptom. It may affect any joint and usually it affects the body symmetrically. For example, the patient may notice pain in the joints of both feet, hands or wrists. The pain may be sharp, aching, shooting, tender or throbbing. Sometimes it may even feel like burning nerve pain. However, some patients may not feel pain specifically, but the joints may just feel tender to the touch. Bone and joint pain can be intermittent or constant, localized or widespread.
Swelling
Swollen joints are also a common sign of rheumatoid arthritis, caused by inflammation. However, every patient is different and the amount of swelling may vary in different parts of the body. The swelling may make it more difficult for patients to perform everyday tasks like typing, cutting food or walking.
Redness & Warmth
In the initial stages, the patient may not notice any visible symptoms, such as redness or swelling. However, skin discoloration occurs when the inflammation widens the skin’s capillaries and they are more visible through the skin. It is usually more noticeable as the condition progresses, but subtle swelling or skin discoloration may also be an early sign. The joints may also feel warm to the touch, even if there is no visible redness.
Stiffness
Another common rheumatoid arthritis sign is stiffness. Specifically, patients feel stiff when the body is attacking the tissue in an active inflammatory state. The patient usually feels stiff for at least 30 minutes. Most patients feel stiff when they wake up, but the feeling may continue throughout the day. In other cases, the morning stiffness may ease throughout the day and then return at night.
Other Signs
There are also other progressive symptoms that may be a sign that the immune system is attacking the body. For example, patients may feel fatigue and loss of appetite. They may also have a slight fever.
Depression
Chronic conditions and psychological symptoms tend to coexist and rheumatoid arthritis isn’t an exception. Experts report that depression may be an early warning sign for rheumatoid arthritis. In fact, research suggests that depression is two to four times more common among people with rheumatoid arthritis than other people.
Weight Changes
Another warning sign of rheumatoid arthritis is unexplained weight loss. Because the condition can cause a loss of appetite, patients may unintentionally lose weight. It can also cause diarrheanausea and vomiting, which can also lead to a decline in body weight. On the other hand, joint pain and stiffness can make it difficult to exercise, which may reduce muscle mass.
Complications from Rheumatoid Arthritis
Joint Damage
This is a serious complication from rheumatoid arthritis. According to a study from the University of Pennsylvania, individuals with rheumatoid arthritis had substantial deficits in muscle density and muscle mass compared to subjects without it. In chronic cases and without treatment, RA can damage cartilage and bone, causing joint deformity. If patients notice a significant decrease in strength, it’s important to contact a physician.
Rheumatoid arthritis can also increase the risk for heart disease and diabetes. Similarly, patients with RA who are also obese have an increased risk for heart disease. It can also affect patient’s employment because it limits mobility.

Risk Factors for Rheumatoid Arthritis

Medical research has not identified a specific cause for rheumatoid arthritis. However, there are different risk factors that may play a role, both genetic and environmental.
Genetic Risk Factors
Researchers have identified a connection between RA and the human leukocyte antigen (HLA). Specifically, HLA is a collection of genes that experts associate with the condition. It does not cause RA, but it increases the likelihood. However, not everyone with the HLA genes has RA. There is only a connection between them.
Environmental Risk Factors
Environmental factors do not cause RA, but if a patient already has a genetic predisposition—such as HLA genes—they can increase the risk, such as second-hand smoke, air pollution, silica mineral, bacteria or viruses and exposure to chemicals and mineral oils.
Other risk factors include gender and age. Although the condition can affect anyone, it is more common in women than men. Researchers have noticed a connection between RA and biological changes, such as with contraception, pregnancy and breastfeeding. Rheumatoid arthritis also tends to affect patients between the ages of 40 and 60, but younger patients can experience it as well. Also, if an individual has a family history of RA, they may be more likely to develop it as well.

Treating Rheumatoid Arthritis

After a doctor makes a diagnosis, they can refer the patient to a specialist called a rheumatologist who will formulate a treatment plan. There is currently no cure for RA, but treatment aims to relieve pain and inflammation in the joints, prevent or slow down joint damage and minimize any dysfunction from pain, damage or deformity. Treatment options for rheumatoid arthritis may include medication, occupational therapy, surgery and lifestyle changes.
Medications 
Some medications can help ease symptoms and slow down the disease’s progression. For example, non-steroidal anti-inflammatory drugs (NSAIDs) are available with or without a prescription in oral or topical forms. They help ease inflammation and pain. Corticosteroids are also powerful, fast-acting anti-inflammatory drugs that aim to slow progression. In addition, disease-modifying anti-rheumatic drugs (DMARDs) work to alter the course of rheumatoid arthritis.
Physical Therapy
Although medication may be effective, it cannot treat the pain and discomfort on its own. A doctor may also recommend physical therapy or exercise. With physical therapy, the patient can learn new, effective methods to perform daily tasks. This can ease stress on the joints. Low-risk exercises can also help reduce inflammation, even if exercise is painful.
Surgery
Patients with rheumatoid arthritis typically do not need surgery, unless they have severe joint damage that limits mobility, daily function and independence. Joint replacement surgery may restore function and relieve pain. The procedure replaces parts of the damaged joints with prosthetics. Surgeons may also repair damaged tendons for improved mobility or realign the joints by fusing them together.
Lifestyle Changes
Rheumatoid arthritis affects many different components of everyday life, including work, social activities and leisure. Thankfully, there are many lifestyle changes to make that may help improve the quality of life in conjunction with other treatment methods.
Exercise
Physicians recommend 30 minutes of physical activity per day, such as walking, swimming or biking. Because RA increases the risk of other chronic diseases, such as heart disease and diabetes, exercise can help lower it.
Keep a Healthy Weight
Obesity can cause complications for RA patients, potentially leading to high blood pressure and high cholesterol. It’s important to maintain a healthy body weight in order to stay healthy and better manage the symptoms.

Stop Smoking
Smoking makes RA even worse and it can also increase the risk of other diseases. It may also interfere with exercise and weight loss.

Supplements for Joint Pain and Arthritis 

Supplements might help RA patients by reducing pain and inflammation in the joints. Although they do not cure the disease or completely eliminate the symptoms, patients can use supplements in conjunction with other forms of medical treatment. Consult a doctor before starting a supplement regimen. They are not an adequate medical treatment. Instead, they simply aim to improve overall health.
D-Glucosamine Sulfate Potassium
The body produces glucosamine naturally from the amino acids glutamine and glucose. It’s required to produce glycosaminoglycan, a molecule that helps repair and develop cartilage as well as other body tissues. Research claims that consuming glucosamine sulfate may raise glucosamine levels in the blood in order to repair or reverse joint damage. One study showed that glucosamine was as successful as acetaminophen in alleviating joint pain. However, the study did not clarify whether the supplement increased joint function on its own.
It is also available as a dietary supplement. Take 1,000 mg of D-glucosamine sulfate potassium powder one to three times daily, or according to a doctor’s directions. Pregnant or breastfeeding women should discuss intake with a doctor.
Boswellia Serrata
Boswellia serrata has anti-inflammatory effects that experts believe may help ease joint pain. In fact, one study shows that boswellia can help relieve pain, swelling and increase mobility in patients with osteoarthritis or arthritis. Some participants experienced a drastic decrease in joint pain, which means boswellia may be as effective as prescription medications in treating arthritis or osteoarthritis.
The recommended dosage for pure boswellia serrata extract powder is 450 mg once or twice daily with food, after consulting a physician.
Chondroitin Sulfate
Chondroitin sulfate helps support cartilage health. It also plays a role in preventing enzymes from damaging cartilage. A 2018 study even suggested that taking 800 mg of this supplement per day may be as effective in relieving joint pain as taking daily 200 mg doses of NSAIDs.
As a dietary supplement, take 750 to 1,500 mg of chondroitin sulfate powder per day, or based on a doctor’s directions.
Devil’s Claw 
Devil’s claw is a common treatment for skin diseases and it may contain anti-inflammatory properties. One study tested it on subjects with various rheumatic conditions and it appeared to significantly relieve pain in the subjects’ backs, knees, hips, shoulders, elbows, wrists and hands. In addition, most of the subjects in the study experienced an improved quality of life. In fact, 60 percent of the participants were able to reduce or stop using other pain medicines.
The recommended dosage for devil’s claw extract powder is 1,000 mg one to three times a day, unless a physician orders a different dosage.

The Bottom Line

Rheumatoid arthritis (RA) is a chronic, disabling and progressive autoimmune condition. It causes pain, swelling and inflammation in and around joints and other organs in the body. Unlike osteoarthritis, the symptoms can appear very suddenly and they may affect any joint in the body. Usually the pain is symmetrical and patients experience pain in joints on both sides of their bodies.
Common symptoms include pain, swelling, stiffness, muscle loss, mild fever and fatigue. Some people may experience depression and the condition also causes complications, such as an increased risk for heart disease and diabetes. Rheumatoid arthritis affects each patient differently.
There is no cure for rheumatoid arthritis, but treatments may help ease pain, reduce inflammation, slow down the disease’s progression and possibly prevent joint damage. Rheumatoid arthritis treatments include medications, occupational and physical therapy or surgery to prevent or repair damage to the joints. Physicians also recommend regular exercise to keep the joints strong and reduce inflammation. Supplements are also proven to help with bone strength and health. They may even help combat rheumatoid arthritis, in combination with other medical treatments.
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Endoscopic Visualization Systems Market Country Level Analysis Endoscopic visualization systems market is analyzed and market size insights and trends are provided by country, product type and end user as referenced above. The countries covered in the endoscopic visualization systems market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa(MEA), Brazil, Argentina and Rest of South America as part of South America. 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Data points such as consumption volumes, production sites and volumes, import export analysis, price trend analysis, cost of raw materials, down-stream and upstream value chain analysis are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data. Get Access Report @ https://www.databridgemarketresearch.com/checkout/buy/singleuser/global-endoscopic-visualization-systems-market Healthcare Infrastructure growth Installed base and New Technology Penetration Endoscopic visualization systems market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipment, installed base of different kind of products for endoscopic visualization systems market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the endoscopic visualization systems market. The data is available for historic period 2011 to 2019. Competitive Landscape and Endoscopic Visualization Systems Market Share Analysis Endoscopic visualization systems market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to endoscopic visualization systems market. The major players covered in the endoscopic visualization systems market report are Olympus Corporation, PENTAX Medical, FUJIFILM Holdings America Corporation, NDS Surgical Imaging, a Novanta Company, Stryker, KARL STORZ GmbH & Co. KG, DePuy Synthes, Carl Zeiss AG, Richard Wolf GmbH, Boston Scientific Corporation, CONMED Corporation, Smith + Nephew, MEDIVATORS Inc., Maxer Endoscopy GmbH, Biovision Veterinary Endoscopy, LLC., Arthrex, Inc, Johnson & Johnson Services, Inc., B. Braun Melsungen AG, MedicalTek Co., Ltd., and Solos Endoscopy., among other domestic and global players. Market share data is available for Global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately. Request for Detailed TOC @ https://www.databridgemarketresearch.com/toc/?dbmr=global-endoscopic-visualization-systems-market Browse Trending Related Reports @ · Circadian Rhythm Lighting Market · Lab automation market · Capnography equipment market · Internal Neuromodulation Devices Market · Neuroprosthetics Market About Data Bridge Market Research: Data Bridge Market Research set forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market Contact: Data Bridge Market Research Tel: +1-888-387-2818 Email: Sopan.gedam@databridgemarketresearch.com
3 Lifestyle Habits that can Cause Acne Breakouts
Your acne is coded in your genes and governed by your hormones. While these two factors are not in your control, your lifestyle which affects your skin equally, IS. Here are the most important lifestyle changes that you can make to reduce your acne breakouts... 1. Clean your mobile phone Your mobile phone is pressed against your cheeks while you chat away with friends. The bacteria from your skin gets transferred on to the screen and stays there till it gets pressed on your skin again. Besides this your phone may have food residue from the time that you were eating and texting and dust from lying on dirty surfaces. If you have acne prone skin, make sure you sanitize the surface of your mobile phone at least once every day. 2. Wash your face less often If you have oily skin which is prone to breakouts, chances are that you are washing your face more than twice daily. That, coupled with acne treatment AHA toners, salicylic acid serums and retinol night creams can over dry your skin. This leads your skin to produce even more oil which in turn feeds acne causing bacteria. Wash your face maximum 3 times a day. Once in the morning when you wake up and shower, once before sleeping at night and an additional time after a workout or outdoor exposure. 3. Reduce your carb intake Refined carbs such as bread, pasta and fried food have a high glycemic index. They increase blood sugar and cause a spike in the hormone Insulin. High glycemic foods are very inflammatory for the body and also disturb your gut bacteria. This in turn disturbs your skin microbiome. Increase your intake of fresh vegetables and salads instead. These are loaded with antioxidants which help your skin in healing faster. If you have been struggling with acne breakouts for a while, getting a little help from your dermatologist could go a long way in getting rid of your acne.
Disruptive Behavior Disorder Treatment Market Trends, Futuristic Overview and Key Drivers with Top Countries Data By 2028
Market Analysis and Insights: Global Disruptive Behavior Disorder Treatment Market Disruptive behavior disorder treatment market is expected to gain market growth in the forecast period of 2021 to 2028. Data Bridge Market Research analyses that the market is growing with the CAGR of 7.25% in the forecast period of 2028 to 2028. The growing cases of behavioral disorders will help in escalating the growth of the healthcare analytical testing services market. Disruptive behavior disorder is a disease that is very frequent among children. It can disrupt a child’s day-to-day life. Children with disruptive behavior disorder, depict a defiant behavior, where they exhibit signs of short-temperedness, aggressiveness, indulge in arguments, fighting, stealing, and disobeying authority. Get More Insights About Global Disruptive Behavior Disorder Treatment Market, Request Sample @ https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-disruptive-behavior-disorder-treatment-market Major factors that are expected to boost the growth of the disruptive behavior disorder treatment market in the forecast period is the increasing of prevalence of substance abuse, the growing cases of mental disorders among the children and teenagers and the rising initiatives taken by several NGOs and the government in turn to increase the understanding on the treatment of disruptive behavior disorder. Furthermore, the increase in the number of campaigns that are being organized by hospitals, clinics and institutes to spread alertness among parents and doctors and the growing of the incidences of the co-existence of two or more disorders in the same person at the same point in time are few of the factors that are anticipated to propel the growth of the disruptive behavior disorder treatment market in the timeline period. However, the reduced quality of diagnosis particularly in the emerging countries and the absence of proper therapies for disruptive behavior disorder are one of the factors that are expected to most likely impede the growth of the disruptive behavior disorder treatment market in the near future. This disruptive behavior disorder treatment market report provides details of new recent developments, trade regulations, import export analysis, production analysis, value chain optimization, market share, impact of domestic and localised market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the disruptive behavior disorder treatment market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth. Know more about this report https://www.databridgemarketresearch.com/reports/global-disruptive-behavior-disorder-treatment-market Global Disruptive Behavior Disorder Treatment Market Scope and Market Size Global Disruptive behavior disorder treatment market is segmented on the basis of type and treatment. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications. Based on the type, the disruptive behavior disorder treatment market is segmented into conduct disorder, intermittent explosive disorder, oppositional defiant disorder. Based on the treatment, the disruptive behavior disorder treatment market is segmented into social and emotional skills training, medication management, individual therapy, comprehensive evaluation, family therapy, group therapy, parenting modification. Disruptive Behavior Disorder Treatment Market Country Level Analysis The disruptive behavior disorder treatment market is analysed and market size insights and trends are provided by country, type and treatment as referenced above. The countries covered in the disruptive behavior disorder treatment market report are the U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America. North America dominates the disruptive behavior disorder treatment market because of the growing of the incidences of the above-mentioned behavioral concerns amongst children and teenagers. Furthermore, the rising alertness about the symptoms of these disorders will further boost the growth of the disruptive behavior disorder treatment market in the region during the forecast period. Asia Pacific is projected to observe significant amount of growth in the disruptive behavior disorder treatment market because of the growing target population. Moreover, the increasing of substance abuse amongst adolescents, mainly in India and China is further anticipated to propel the growth of the disruptive behavior disorder treatment market in the region in the coming years. The country section of the disruptive behavior disorder treatment market report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points such as consumption volumes, production sites and volumes, import export analysis, price trend analysis, cost of raw materials, down-stream and upstream value chain analysis are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data. Get Access Report @ https://www.databridgemarketresearch.com/checkout/buy/singleuser/global-disruptive-behavior-disorder-treatment-market Healthcare Infrastructure growth Installed base and New Technology Penetration The disruptive behavior disorder treatment market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipment, installed base of different kind of products for disruptive behavior disorder treatment market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the disruptive behavior disorder treatment market. The data is available for historic period 2010-2019. Competitive Landscape and Disruptive Behavior Disorder Treatment Market Share Analysis The disruptive behavior disorder treatment market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to disruptive behavior disorder treatment market. The major players covered in the disruptive behavior disorder treatment market report are Lilly, Pfizer Inc., Johnson & Johnson Services, Inc., Bionomics, Highland Ridge Hospital, Lakeview Health, Boston Children's Hospital, Integris Health, ST. JOHN, Springwoods Behavioral Health., Alliance Health Durant, Midwest Health Center., Chelsea Therapeutics International, Ltd., DURECT CORPORATION, among other domestic and global players. Market share data is available for global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately. Request for Detailed TOC @ https://www.databridgemarketresearch.com/toc/?dbmr=global-disruptive-behavior-disorder-treatment-market Browse Trending Related Reports @ · Deep Brain Stimulation Systems Market · Continuous Glucose Monitoring Market · G-Protein Coupled Receptors (GPCRs) Market · Homecare Surgical Drains Market · Tumor Infiltrating Lymphocytes Market About Data Bridge Market Research: Data Bridge Market Research set forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market Contact: Data Bridge Market Research Tel: +1-888-387-2818 Email: Sopan.gedam@databridgemarketresearch.com
3 Ways to Get Rid of Stubborn Dark Circles
Dark circles have many causes, and you have probably tried many under eye creams already in vain. Read on to find out how you can quickly get rid of your under eye problems with the help of your cosmetic dermatologist. 1. Retinol Retinol is a holy grail anti-aging ingredient. It is a vitamin A derivative that signals your skin to repair and rejuvenate. When you use it to get rid if dark circles, it is not only able to remove under eye pigmentation, but also reduce under eye wrinkles and crows feet lines. Get the best results by applying a hyaluronic acid serum, layering it with retinol and topping it off with a ceramide moisturizer.  2. Under Eye Dermal Fillers Dermal fillers such as Juvederm and Restylane are ideal if you have sunken eyes. Such under eye hollows cast a shadow and make your dark circles appear worse than they are. Dermal fillers for under eye dark circles is a very satisfying treatment. You walk in to your dermatologist's clinic looking tired and walk out transformed! The results may last for 6 months to 2 years depending on which fillers you choose to have. 3. PRP Treatment PRP treatment appeals to almost everyone as it is extremely natural. There are no injections, no chemicals and no lasers involved in this one. The treatment uses your own plasma growth factors to rejuvenate your under eye area and treat dark circles. The treatment works best along with micro-needling to stimulate collagen and break down under eye pigmentation. You will need 1 session every 4 to 6 weeks for up to 4 times to see complete results. Feel free to discuss these treatment options with your dermatologist and check if they are right option for your under eye problems.