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What is Durogesic medicine? Usage, dosage & usage |Tracuuthuoctay
What is Durogesic medicine? Durogesic is a transdermal therapy line that delivers fentanyl, a powerful opioid pain reliever, that continues to enter the bloodstream for 72 hours. Durogesic is a drug in the form of a transparent rectangular tape consisting of 1 protective film and 4 functional films. These classes include: Film after polyester film coating; fentanyl (2.5 mg / 10 cm2) and USP standard alcohol storage system (0.1 ml / 10 cm2) gelated with hydroxyethylcellulose; The ethylenevinyl acetate polymer film helps to control the rate of fentanyl release; Silicone adhesive film. Before using, remove the protective film from the adhesive film. Patches size 10 and 20cm2. Durogesic drug information Active ingredient: Fentanyl. Classification: Analgesics of the opioid group. Legal group: ETC prescription drugs - (Ethical drugs, prescription drugs, Prescription only medicine). ATC code (Anatomical Therapeutic Chemical): N01AH01, N02AB03. Brand name: DUROGESIC. Manufacturer: Janssen-Cilag. DUROGESIC drug prices: Comment at the end of the article for price notification. What DUROGESIC drugs Uses and drug prices DUROGESIC (1) DUROGESIC drug dosage and administration Dosage form - Content: System of drugs released through the skin: box of 5 pieces. Each piece of DUROGESIC 12mcg / hour *, 5,25cm2: Fentanyl 2.1mg. Each piece of DUROGESIC 25mcg / hour, 10.5cm2: Fentanyl 4.2mg. Each piece of DUROGESIC 50mcg / hour, 21cm2: Fentanyl 8.4mg. Indications & Contraindications of the drug Durogesic Point Strong pain relief requires the use of opioid pain relievers. Durogesic is a transdermal therapy system that delivers fentanyl, a powerful opioid pain reliever. Contraindicated Patient is known to be sensitive to fentanyl or the adhesives contained in the patch. Acute or postoperative pain because there is no opportunity to titrate a dose within short term use; because severe or life-threatening hypoventilation can result. Severe respiratory failure. Dosage of durogesic drugs Selection of starting dose: The size of the starting Durogesic patch should be based on the patient's history of opioid administration, including opioid tolerance, if any; as well as the patient's current clinical profile and drug use status. Patients who have never taken opioids: Durogesic doses of at least 25 mg / hour should be used at baseline. Opioid tolerant patients: Switch from oral or injectable opioids to Durogesic, the sequence is as follows: Calculate the need for the previous 24 hour pain reliever. All oral and intramuscular doses in this table have been evaluated to be equivalent to 10 mg intramuscular morphine for analgesic efficacy. * In clinical trials, daily dose data of oral morphine were used as a basis for conversion to durogesic doses. Standard maintenance therapeutic dose: The patch should be replaced every 72 hours. The dose should be adjusted individually until an analgesic effect is achieved. If the analgesic effect is insufficient after the initial dose, the dose may be increased after 3 days. Thereafter, the dose may be adjusted every 3 days. The dose titration should be increased by 25 mg / hour at a time (oral morphine 90 mg / day = Durogesic 25 mg / hour) and assess the patient's pain. More than 1 Durogesic patch may be used when the dose is over 100 mg / hour. Discontinuation of Durogesic treatment: If it is necessary to discontinue Durogesic, replacement with other opioids should be gradual, starting at a low dose and gradually increasing. This is because fentanyl levels gradually decrease after removal of the patch, and blood fentanyl levels decrease by 50% by about 17 hours or so. Xem thêm thông tin thuốc tại Tracuuthuoctay: https://tracuuthuoctay.com/durogesic-thuoc-gi-cong-dung-va-gia-thuoc-durogesic/
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NITROFURANTOIN Nitrofuran urinary antimicrobial drug | Tracuuthuoctay
What is Nitrofurantoin? Nitrofurantoin is an antibiotic that fights bacteria in the body. The drug is used to treat urinary tract infections. Nitrofurantoin may also be used for purposes not listed in this medication guide. Pharmacology and mechanism of action Nitrofurantoin is an antibacterial, nitrofuran derivative, effective against many strains of gram-negative and gram-positive urinary tract bacteria. The mechanism of antimicrobial action of nitrofurantoin is unlike that of other antibacterial drugs. Nitrofurantoin is reduced by bacterial flavoproteins to mediate the inactivation or modification of the bacterial ribosomal protein and some other macromolecules. Therefore, nitrofurantoin inhibits the biosynthesis of proteins, DNA, RNA and cell wall biosynthesis of bacteria. Nitrofurantoin has effect on many strains of E. coli, Enterococcus. Rare drug-sensitive bacteria become resistant during treatment. The minimum inhibitory concentration is about 32 micrograms / ml. The antibacterial activity of nitrofurantoin increases in acid pH urine. Nitrofurantoin is quickly and completely absorbed from the gastrointestinal tract, the large crystalline form is absorbed and eliminated more slowly than the baby crystal form. With therapeutic doses, the antimicrobial concentration of nitrofurantoin in plasma is not achieved due to rapid elimination, plasma half-life is about 0.3 to 1 hour. Nitrofurantoin is metabolized in the liver and tissues; about 40% is excreted unchanged in the urine and attains a high concentration in urine, about 200 micrograms / ml. The rate of excretion depends linearly on creatinine clearance, so for patients with reduced glomerular function, the effectiveness of treatment is reduced and the risk of poisoning increases. Nitrofurantoin brown color urine. Drug information nitrofurantoin International generic name: Nitrofurantoin. ATC code: G04A C01. Drug type: Urinary antibacterial nitrofuran drug. Category: Medicines against urinary infections. Drug form and content Tablets: 50 mg, 100 mg; Capsules: 25 mg, 50 mg, 100 mg; mixed. Solution: 25 mg / ml (300 ml). Drug prices NITROFURANTOIN Comment at the end of the article to be informed of the price Indications for the use of nitrofurantoin Uncomplicated and chronic acute urinary tract infections caused by E. coli, Enterococcus, Staphylococcus saprophyticus, Staphylococcus aureus and susceptible strains of Klebsiella, Enterobacter. Contraindications to the use of nitrofurantoin The drug Nitrofurantoin is contraindicated to use for those who are allergic or hypersensitive to some of the ingredients in the drug or those who fall into the following cases: Severe kidney disease, impaired kidney function Have liver problems, impaired liver function A history of jaundice Urinary retention, less urination Anemia, vitamin B deficiency, glucose deficiency - 6 - phosphate dehydrogenase Diabetes Asthenia Peripheral neuropathy Inflammation of the optic nerve Pregnant women are in the last 2 - 4 weeks of pregnancy There are also a number of other objects that are not required to use. Patients wishing to use drugs, please consult your doctor before use, to avoid serious consequences later. Xem thêm thông tin thuốc tại Tracuuthuoctay: https://tracuuthuoctay.com/nitrofurantoin-thuoc-nitrofuran-khang-khuan-duong-tiet-nieu/
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What is osteoporosis? Osteoporosis, also known as brittle bones; osteoporosis, is the thinning of the bones and the density of substances in the bones is gradually thinning. They make bones more brittle, vulnerable, and break even with mild trauma. Osteoporosis is difficult to detect until the bone is broken. Many people think that osteoporosis is a natural and inevitable part of old age. However, medical experts today believe that osteoporosis can be prevented. Classification of osteoporosis Based on the cause, the disease is divided into two categories: primary osteoporosis and secondary osteoporosis. Primary Osteoporosis: A type of osteoporosis with no other etiology other than age and or menopause in a woman. This is due to the aging of osteoblasts causing an imbalance between bone resorption and bone formation, resulting in osteoporosis. Secondary Osteoporosis: The type of LX found the cause related to a number of chronic diseases, related to the use of some drugs…. Causes of secondary osteoporosis: Endocrine diseases: Hyperthyroidism, diabetes, enlarged limbs ... Gastrointestinal diseases: gastric bypass, lack of nutrition, chronic liver disease. Arthritis: Rheumatoid arthritis, spinal disease ... Cancer: Kahler ... Inherited disease: iron pigmentation disease ... The cases of using corticosteroids, heparin, using diuretics for a long time ... What are the symptoms of osteoporosis? The disease has no obvious symptoms. The common signs are weight loss and back pain. Osteoporosis is a major cause of fractures in postmenopausal women and the elderly. Osteoporosis fractures occur most often in the hip, spine, and wrist, but any bone can be affected. Fractures are a common symptom of osteoporosis and can lead to disability. The most common fractures are: wrists, spine, shoulders and hips. Sudden back pain symptoms, frequent pain (pinched nerve root pain), and rarely spinal cord compression or Equina cauda syndrome. Long fractures impair mobility and may require surgery. In particular, hip fracture, which often requires prompt surgery, because of the serious risks associated with it, such as deep vein thrombosis and pulmonary embolism, and increased mortality. What causes osteoporosis? Bones are always in a state of renewal - new bones are made and old bones are broken down. When you are young, your body makes new bone faster than it breaks down old bones, and your bone mass increases. After the early 20s, this process slows down and most people reach their maximum bone mass by age 30. As people age, bone mass is lost faster than bone is produced. Your likelihood of having osteoporosis depends in part on the amount of bone you gained when you were younger. Peak bone mass is somewhat inherited and also varies by ethnic group. The higher your peak bone mass, the more bones you have “in the bank” and the less likely you are to have osteoporosis as you age. Causes of osteoporosis - include: age, race, lifestyle, medical conditions, and treatments. Some of the risk factors for osteoporosis are out of your control, including: Gender: Women are more likely to develop osteoporosis than men. Age: The older you get, the greater your risk of osteoporosis. Race: You are most at risk of osteoporosis if you are white or of Asian descent. Family history: A parent or sibling with osteoporosis puts you at higher risk, especially if your parent has a hip fracture. Skeletal size: Men and women with a small body frame tend to be at higher risk as they may have less bone mass to draw off as they age. See more disease information at Tracuuthuoctay: https://tracuuthuoctay.com/benh-loang-xuong/