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Pharmacovigilance & Best Pharmacovigilance Training
Pharmacovigilance or drug safety in lay man language. Pharmacovigilance is the science that connects to the detection, collection, monitoring, assessment, and prevention of the negative effects of pharmaceutical products. Pharmaceutical vigilance mainly involves the evaluation of information and facts provided by the health care providers. Pharmacovigilance excessively focuses on the adverse reactions of drugs, defined as the response to an unintended and noxious drug. It also includes the inefficiency of the drug. Errors like abuse and overdose of the medication and drug exposure during pregnancy despite the lack of an adverse effect are considered to result in an adverse drug reaction. Pharmacovigilance is extremely important to determine the usability and the effects of any drug. Any pharmacovigilance service centre undergoes special clinical research training through several clinical research course. This is one of the major departments of any pharmaceutical company. Any pharmacovigilance process mainly consists of four stages. These stages include: Pharmacovigilance Detection Process: This is the first stage in the vigilance process of any drug. It begins with the safety information that comes from several sources, which may be either solicited or unsolicited. Those that are received as a result of the targeted data collection form the solicited data sources. These include clinical trials with one or three phases and post-marketing, including interventional and non-interventional studies and research. Solicited sources also include organized systems that have a well-defined public health purpose and a scientific and clinical purpose. Solicited sources also include personalized programs forum-registered drug administration. Unsolicited sources are spontaneous and those which are received without any form of request. These sources generally include regulatory authorities, literature reports, patients and healthcare providers, license providers, internet, journal, books, and other resources. Pharmacovigilance Assessment Process: After the initial collection of all the required data, ICSR assessment is conducted. This assessment mainly includes: 1. Triage: This phase of potential adverse event report involves the major function of establishing the validity of an ICSR. Any valid ICSR should mainly possess an identifiable patient, an identifiable reporter, suspect drug, and an adverse event. 2. Data Entry: Any pharmaceutical company maintains its own suitable database. After validation, the drug parameters are entered into this safe database. The further steps in data entry include determining seriousness, coding the adverse events, assessing causality, assessing labeling, and concise and legible narrative writing. 3. Questioning Process: Any clarifications and additions discrepancies are raised and cleared during this phase of the assessment. 4. Reviewing: Physicians and other professionals review the safety regulations that emphasize the seriousness, causality, labeling, etc. 5. Closure of the case: The completed report, including all the parameters, is submitted to the required authorities. . Learn Best Clinical Research Course. Understanding and Analysing the Drug safety profile: The data collected is reviewed and analyzed to understand the safety profile of the drug using a periodic benefit-risk evaluation report which includes data collected from all forms of clinical trials and spontaneous trials for which a risk-benefit analysis is conducted. Particular adverse reaction follow-up queries are used to get structured information on reported suspected adverse reactions. A risk management plan and development safety update report is also made. Signal analysis is also conducted. Prevention of the negative effects: This phase is the final stage of pharmacovigilance. Performing minimization of risk activities in order to update the summary of the product description, a leaflet of patient information, labeling and packaging, and legal status of the medication is done in this phase. This stage also includes the monitoring of this minimization of risk activities. Collaboration in the field of pharmacovigilance forms the foundation of the WHO program for international drug monitoring. These reports are generally analyzed locally and could lead to action within the country itself. The WHO program membership of any country helps them keep up with similar researches and reports that are made worldwide. When there are multiple reports of a particular drug, this process may lead to a detection of a signal which could be hazardous to the human body. Ecopharmocovigilance: Procedures for monitoring the drug concentrations and the ill effects of these drugs on the environment lack despite the FDA. A concept including environmental pharmacology and pharmacovigilance focuses on this domain. The activities of ecopharmacovigilance include increasing the facts available on the environmental effects on the drug, use of environmental risk management plans, tracking new data on the exposure to the environment, risk identification, etc. There are several pharmacovigilance courses that focus on this aspect of the field.
How to Build a website like Upwork
The gig economy gradually takes over the world. After the outbreak of Covid19, it is getting clear that freelancers hardly want to return to their 9-to-5 office routine. Businesses, in their turn, seem satisfied with the status quo. As we can see, the gig economy with its flexibility and lower commitment proved beneficial for both parties. This latest trend resulted in the emergence of so-called freelance marketplaces. These are platforms where freelancers and businesses can collaborate. You have probably heard about Upwork, which is the biggest and most popular freelance marketplace. This article is dedicated to the process of building a website like Upwork. We will discuss such terms as a value proposition and revenue model. Also, you will find out what features your platform should have and what tech stack you need to build them. The definition of the freelance marketplace Let’s start with the definition of the term “freelance marketplace”. This way, it will become clearer for you what kind of platform you are going to launch. A freelance marketplace is an online platform where employers can hire specialists for any kinds of remote projects. The key benefits of freelance marketplaces like Upwork are: - Fast access to gifted professionals. - Cost-effectiveness. - The opportunity to hire talents on demand. Popular freelance marketplaces are Upwork are Fiverr, Toptal, Freelancer.com, and PeoplePerHour. The key challenges of freelance marketplaces Let’s take a look at the challenges associated with freelance online marketplaces. Late payments - after the outbreak of Covid-19, freelancers often face payment delays. Necessary currency exchange - contractors have to convert US dollars into their national currency. In addition, the payment gateways popular in their countries may not be available on the freelance platform. Quantity vs. Quality - fewer acceptance criteria mean a large talent pool. However, the quality of services provided by freelancers can be unsatisfactory. At the same time, the rigorous selection process can create a deficiency of contractors. The success story of Upwork Upwork started as two separate freelance marketplaces. They were called eLance and oDesk. In 2013 these websites merged into a single platform Elance-oDesk. After the rebranding, the website was renamed into Upwork. Today there are more than 10 million freelancers and over a million employers on Upwork. Upwork functioning Upwork belongs to the generic bidding marketplaces. Let’s find out what his term means by analyzing each of its components. Generic - Employers can find professionals for any kind of remote projects. Bidding - Candidates set the price and employers the most suitable price option. Marketplace -There are two sides on the platform interacting with each other. These are sellers (in our case, freelancers) and buyers (in other words, employers). So how can you find a specialist for your project? Let’s discuss two available options: 1. Finding a predefined project Browse a project catalogue with predefined projects on Upwork. Enter your keywords in the search box and filter results based on specific parameters. They include category, talent options, budget, and delivery time. If you found a suitable solution, proceed to this project and check available service tiers. Contact the contractor if you want to specify the project details or get additional information. Below you can see the example of a predefined PWA project on Upwork. 2. Hiring a specialist for a custom project Create a job post with a detailed project description and required skills. If a specialist finds it interesting, they will send you a proposal with basic info and the bid (hourly rates or fixed price for a completed task). Below you can see the example of a job post on Upwork: Revenue model Upwork uses two revenue models that are service fee and subscription. Let’s take a closer look at each of the monetization strategies. Service fees It should be noted that service fees are different for freelancers and employers. Thus, contractors have to pay 5%, 10%, or 20% of each transaction. The percentage is defined by the sum freelancer billed an employer. Employers, in their turn, are charged with a 2.75% payment processing and administration fees. Client membership The platform offers two plans. The Basic plan is free. To use Upwork Plus, employers will have to pay $49.99 per month. How to build a website like Upwork: Step-by-step guide Select your niche Define which freelance marketplace you are going to build. Will it be a general one like Upwork? Will you choose a narrow niche and create a marketplace for designers or content writers? For example, 99designs.com is a platform for hiring web designers. You can see its homepage below: Create a value proposition There are two reasons why you should have a clear value proposition: 1) To highlight the advantages of your product and differentiate yourself from market rivals. 2) To get the upper hand by covering drawbacks in your niche. If you do not know where to start, begin with the following values your platform can bring to employers and freelancers: - Accessibility; - Price; - Time. Choose the type of your freelance marketplace Your next step is to select the right freelance marketplace type. You can use of of the following options: - Local freelance portals. - Freelance online platforms focused on short-term jobs; - Freelance marketplaces for long-term projects; - Industry specialized freelance marketplaces; - Part-time jobs websites; - Enterprise based freelance portals; - Contest platforms. Take a look at the example of live design competitions on Arcbazar. Define the revenue model Below you can see the most common monetization strategies for freelance platforms. We hope that you will be able to choose the most suitable option. - Gigs and packages model; - Subscription; - Freemium model; - Deposit model; - Advertisement; - Custom price; - Mixed model. Choose the must-have features Consider the functionality you want to implement on your freelance marketplace platform thoroughly. It will help you stand out from the competitors and attract more users. The list of required features for a website like Upwork looks the following way: - Registration and user profiles; - Search and filters; - Job listing; - Bidding mechanism; - Messenger; - Review and ratings; - Project management tools; - Payment gateways. Select the right technology stack Let’s overview briefly what programming languages, frameworks, and tools you can use to build a website like Upwork. Back-end - Upwork opted for PHP and Java programming languages. However, you can use other technologies for example Ruby and Ruby on Rails. They are a good choice for online marketplace development projects. Front-end - Upwork chose Angular.js and Bootstrap. At Codica, our preferred tech-stack for front-end includes React, Vue.js, JavaScript, HTML5, and Gatsby. Third-party tools and integrations. Upwork uses different tools and apps to achieve its business goals. We should mention Jira, Slack, Google Workspace, Marketo, and Zendesk are the most popular among them. Final words We hope that our thorough guide on building a website like Upwork proved helpful for you. If you have an idea of creating a freelance marketplace, do not hesitate and contact us. For more information, read the full article: How to Build a Website Like Upwork and How Much Does it Cost?
How To Create A Secure IoT Network To Guard Your Connected Devices
IoT has created a bridge between the physical world and the Virtual World. With all conviction, we can expect IoT as an indispensable part of our lives. But as the IoT implementations are growing, the security concerns are also growing at the same pace. And Today, being a leading IoT service provider, we are going to share how you can create a secure IoT network that will keep your connected devices as safe as possible. Steps To Create a Secure IoT Network Let me tell you very straight that securing the IoT network doesn’t require a completely new or complex set of ideas and principles. The core lies in the best practices while designing the IoT solution.  As there are many small to big things considerably, We can say IoT security is a multi-faceted effort that requires big moves as well as small adjustments to ensure networks, data, systems, and devices are protected.  What is Security By Design? Security by design is a practice that ensures security as a crucial consideration at all stages of product creation and deployment. Often in the IoT developments led by speed and other priority factors, the security considerations are included late in the design and prototyping phase. That results in security breaches. It’s important to remember that as devices and their firmware get obsolete and error-prone in time, they may become an attractive target of bad cyber actors. Hence, it’s crucial to manage the lifecycle of security devices and cloud spectrum to reduce the attack surface. The sad part is that most of the time, robust and long-term security strategies are overlooked during IoT implementations. Security is not a one-time activity, rather an evolving part of the IoT ecosystem that should support IoT deployments’ lifecycle in: Adding new devices and decommissioning others, Onboarding to new cloud platforms, Running secure software updates, Implementing regulated key renewals, Maintaining large fleets of devices. All these activities require comprehensive management of identities, keys, and tokens. To avoid time-consuming and expensive services in the field, IoT Security lifecycle management solutions must facilitate updates remotely while executing them across large scale device fleets. Now let’s see the Security concerns in two popular forms of IoT: Tips To Secure Consumer IoT Devices Smart speakers, domestic appliances, connected toys, and smart locks are all potentially vulnerable if not properly secured by design and during their expected lifespan.  For example, someone who owns a Google Nest Hub and other Xiaomi Mijia cameras around his home claimed that he received images from other people’s homes, randomly, when he streamed content from his camera to a Google Nest Hub. There are many such examples where the design loopholes have caused many consumers more harm than good. The good news is that ETSI recently announced ETSI TS 103 645, the first worldwide standard for consumer IoT security. This sets a benchmark for how to secure consumer products connected to the internet and aims to promote best practice. Additionally, here we are going to share tips that will help you in designing a secure IoT network for your consumers and smart homes. Know Your Network and The Connected Devices – When we put together several devices over the internet that potentially leaves your entire network vulnerable. It’s common to lose track with an increasing number of equipped devices. Hence it’s essential to know your network — the devices on it and the type of information they’re susceptible to disclosing.  Assess the IoT Devices on Your Network First, know which devices are connected to your network, audit your devices to understand their security posture. While selecting devices check for newer models with stronger security features, etc. Further, before making a purchase, read up to understand how much of a priority, security is, for that brand. Input Strong Passwords to Protect Your Devices and Accounts Use strong and unique passwords that will assist you in securing all your accounts and devices. Get rid off the common passwords like “admin” or “password123.” Make use of a password manager, if needed, to keep track of all your passwords. At the same time ensure that you and your employees don’t use the same passwords across multiple accounts and be sure to change them periodically. Choose a Separate Network for Your Smart Devices Separating networks is a smart way to protect your smart devices in the IoT network. With network segmentation, even if attackers discover a way into your smart devices, they can’t access your business data or sniff on that bank transfer you did from your personal laptop. Reconfigure Your Default Device Settings Usually when we receive our smart devices they are packed with default insecure settings. And things become worse if we do not modify their configurations. As weak default credentials, intrusive features, ports and permissions need to be assessed and reconfigured as per your requirements. Install Firewalls and Other IoT Security Solutions to Identify Vulnerabilities To safeguard your Smart homes and other consumer IoT networks block unauthorized traffic over the wire through firewalls. At the same time run intrusion detection systems/intrusion prevention systems (IDS/IPS) to monitor and analyze network traffic. This is where you can use an automated scanner to uncover security weaknesses within your network infrastructure. Use a scanner to identify open ports and review the network services that are running. Now let’s check out the key steps to protect your enterprise network against modern security threats. Steps To Protect Your Enterprise IoT Network We have seen many manufacturing industries adopting IoT and growing. However many aren’t serious enterprise security, that’s a mistake. Because we have seen that In 2018,  21% of companies reported a data breach or cyberattack due to insecure IoT devices. So do not let that happened with you and follow the steps below to protect your enterprise IoT network: Step 1:  Be alert of the risk As IoT is relatively new as compared to IT, hence some of the threats are newer and not as widely used, and make companies reluctant. But we forget that IoT security is like buying insurance. We think we won’t ever have to use it, but the odds are, we might. So it’s better to realize that with a lot of connected devices in use, we might have vulnerabilities that need to be minimized and fixed. Step 2: Design a Secure network architecture The Ponemon study found that less than 10% of organizations are confident they know about all of the printers, cameras, and building automation systems on their networks that are connected to the Internet. Hence, it’s essential to carefully design your network architecture. And protect your devices from the network, and further protect your network from the devices. Step 3: Observe Your Suppliers and Vendors Attackers are smart today, they may target you through the suppliers and vendors. So do not underestimate the vulnerability that comes along with companies you connect with.  It’s a better practice to include the security practices as part of your vendor risk management process. Step 4: Practice For the Data Breach You must prepare for an IoT data breach the same way you prepare for disasters like fire, earthquake, or other. Make a plan, have a regular drill, and keep the plan updated. It’s good to have regular exercises to test your data-breach preparedness.  How will you tackle the situation If you get breached? you should have a well-documented plan for the same. Step 5:  Control what you can, and learn to live with calculated risk It is important to realize that while you should do everything that you can do, you can’t expect to prevent everything. So learn to live with a calculated risk. For something that’s as crucial as a backdoor into your entire network, which is really what a smart-building management company represents, you really need to keep a close eye on their security practices. Step 6: Start now, and get ready for whatever comes next IoT being an emerging technology can not and should not be removed from our enterprises.Although there is risk that comes with it but like all excellent growth you need to take that risk and better prepare yourself to reduce the chances of mishappening like data breaches and others. You know new devices are coming with each passing days, hackers are becoming more creative, and the risks are getting more profound and devastating. So, Be aware and take proactive steps to secure your IoT network. And if you are looking for any other assistance in IoT services, do not forget to check our IoT services page.
Last-Minute Gifting Ideas
Brainstorming for some special gifts for your loved ones can be difficult at times especially if it's very last minute! There come many occasions where we are bound to gift our loved ones or our partners but we run out of ideas or there is so little time left. This article might turn out to be useful for you and give some inspiration to pick out some last-minute gifts for your loved ones. 1) Perfume I know it is a very common gift but it is a no-brainer and actually a very useful gift. You’ve got to make sure that it is a fragrance which is suitable for all occasions and mostly everywhere they go. The fragrance should at least last 8 to 10 hours. You can select from the wide range of perfume choices from this amazing alternative to eBay. 2) Personalized Cuff Links Giving something personalized adds a little personal touch to it which makes the gift all the more meaningful. There are various websites that design personalized cuff links with initials on them. I understand that getting something personalized is not possible last minute but you can always look for other designs across the web too. 3) Electronic Gadgets Gifting gadgets is a really cool option as well. If you specifically know what the other person wants then you can go for that as well. If they are into PlayStation or video games, you can gift them a PS5 if you have your budget. It would be a really cool gifting option. 4) Airpods or Headphones If your loved ones are really into music or love to have some music while working out or doing some chores, this would be the best gift for them. You would find various color options and models, make sure you choose the best one! 5) Kindle If your loved ones are into reading books a lot, this would be the perfect option for them. Most of the time, book lovers get short of space to store their books. In such cases, Kindle comes much handy. It takes minimal space and stores a maximum number of books. 6) Coffee Machine There are so many people who are immense coffee lovers. But it gets difficult to spend money each time they need to drink coffee or spend so much time beating it to get it ready. In such cases, gift them a coffee machine and they would be the happiest people on this planet. 7) Chocolates and Flowers Now I know it is a very easy-peasy option but for the last minute, it can do wonders and you can never go wrong with it. Because ultimately it is the thought process and feelings behind it that counts, isn’t it? So pick out their favorite chocolates and a super elegant flower arrangement and you’re good to go. 8) Watch I personally really like watches. If your loved one is a watch person or if they don’t have any watches yet, you can help them build a watch collection. So, this is a great idea too. You can find a wide variety of watches online as well as from your nearby shops. These were some last-minute options that would never go wrong. I really hope I came out as a help to you in finding a perfect gift for your loved ones last minute. So, get some amazing gifts for them!
How English helps in making one feel confident and powerful?
How the English language lets you lead the stage? Through the sands of time, the British Empire expanded and ruled over several different countries. The British Empire acquired approximately a quarter of the earth’s surface and ruled it with an iron fist. This act has made it one of the most popular languages in today’s world. In the past, the British forced their language over the people they ruled over to speak English which has led to the widespread knowledge of the language. Many of these countries have also made English their official language, even if it isn’t their native language. The English language may have had a complex past, but it certainly has a bright future. Language Classes in Pune. As so many people know to speak the language helps in connecting with people globally. Today, fluent English can also help with careers and professional life. The language’s popularity has several perks in all respects today, making it extremely useful to know. A language is learned by catching several worlds and associating them together. The English language changes over the years, and its influence and derivations from various other languages make it easier to grasp and understand. How English helps in making one feel confident and powerful? The feeling of confidence comes from within. English being the most needed language in today’s world makes many feel nervous or insufficient. Many are also governed by their beliefs and dislike for the language due to cultural reasons and paradigms. But English is such a language that it brings a sense of power to the speaker. It also helps transmit that power in the form of confidence, which helps deliver the message with a more lasting impact on the audience or crowd. This sense of confidence may arise within the speaker either due to the popularity of the language or the ease of communicating and engaging with the listeners. It is how English helps one rule the stage. Here’s what brings out confidence and power with the knowledge of the English language: · English knowledge improves cognitive flexibility: One of the most significant benefits of learning a second language is cognitive flexibility. In layman’s terms, how stretchy one’s brain is. The ability to switch between languages is vital. It begins with the identification of the language. Thus, being multilingual improves cognitive flexibility. It also helps in improving concentration and focusing abilities. Even understanding a joke or choosing a descriptive word can be signs of cognitive flexibility. Increased cognitive flexibility and focus give a person the ability to connect and fit in with people more easily and boost confidence. · Travelling and cultural awareness: Learning another language can also help learn about another culture, as language is a critical aspect of culture. Learning English brings exposure to the culture of all the English-speaking countries. It is a popular language; it brings a substantial amount of learning and indulging with it. It helps one communicate better with people and impart their knowledge on the subject can make them more interesting, boosting confidence. Language Classes in Pune. Knowing English allows one to travel to countries across the world and interact with the people and the cultures there. · Long-term learning and improved life: Although the initial stages of learning the language may be tricky, eventually, with time, English becomes an integral part of a person’s life and gives a boost of confidence to the speaker. Accepting that mistakes will be made and improving them makes one feel the need to take more risks on the language front. Eventually, understanding that learning a language is a long-term process that involves continuous learning makes one feel at ease with the idea of trying new things. It expands one’s horizons and gives them the courage to try harder and get better in the language. Increased creativity: As learning English can help the brain become more flexible, it enhances the mind’s creativity. This flexibility can also lead to increased problem-solving capabilities and improve interaction with the world and its people. Because the English language is spoken by so many people worldwide, it is also the primary entertainment language. English knowledge can help indulge with these and can also influence a person’s thoughts and behaviour. Expanding connections and building relations: One of the best things about learning English is that it helps build connections with people around the world as English is one of the most popular languages today. English is a very social language, and learning is equivalent to social skills. As one begins learning English, practicing by having one-on-one conversations with English speakers becomes easy. Many online platforms and other institutes provide language Classes, English speaking classes, English speaking courses, etc., to improve one’s fluency in English. Expanding connections and building new relations, publically speaking in English, even makes one easily rule the stage. Getting comfortable in speaking English is not a hard task. Its popularity already has a great influence over most native languages as well. Hence, grasping it and mastering the language is not that challenging. The art of leading the stage all comes with the ease and fluency of this fine language.
Key Steps For An Effective Fleet Maintenance Program
Fleet business comes with its dynamics and it requires continuous technology upgrades for its improvisation. As technology is advancing and providing some of the best solutions to better your fleet management services, allowing you to work upon some of the key implementations that help you build a successful fleet maintenance program. To develop a successful fleet maintenance program your priorities should be to work on some of the leading strategies that are currently missing in your business, and their incorporation could bring in the much-needed betterment in the overall performance and upscale of your fleet business. We have listed down some of the key steps that will help you evolve your fleet maintenance program: 1.Identification of the Requirements The initial step is to identify and find the requirements for your fleet business to be upgraded. Identify the assets you can look upon the preventative and corrective maintenance in developing the crucial strategy. Proper maintenance of your fleet is equally important, with corrective maintenance you can include the scheduled corrective maintenance and breakdown maintenance. This helps out in the optimal maintenance of your fleet assets. A clear strategy needs to be followed, when it comes to maintenance of your fleet assets there shall be no lapses between the operations and handling of the procedures. A fleet maintenance software becomes useful for the management of your fleet assets and other important details. 2. Planning To get your fleet management program successfully delivers upon the fleet business requirements. You require proper planning and execution. The important thing to keep in mind during your planning stage is to know what you are working on and solving the right problem. For instance, to solve the fuel maintenance problem, you can not just ask the vehicle drivers to work out the problem as the driver alone can’t get you the solution. You will have to plan out well with the team to figure out what all lapses are occurring and get the solution. With quintessential planning, you can upscale the quality of work that empowers your fleet business with increased productivity and reduced downtime. 3. Scheduling of The Work Timeline With the scheduling of the tasks, a fleet business can perform well and also keep a tab upon the statistics. Scheduling majorly brings its usability in letting us know when the work needs to be done. Accordingly, we manage our assets for the best outcome. Here a glimpse of how scheduling helps: It provides the operations manager with the maximum permissible downtime for the asset and the best time for it to commence. For assets gather the work requirements that can be completed in the given time frame with no lapses. With every new task being generated upon you should strategize well ahead in scheduling the task. It allows you to manage your fleet with an accuracy of well-planned and scheduled efforts. It gives the required details for tracking the performance of your assets for the overall fleet business progress. 4.Executing the Plan An optimal fleet maintenance process allows a fleet business to get the task right the first time. To Ensure that each fleet personnel is properly trained and equipped to undertake the assigned tasks, or if you’re outsourcing the workforce, then verify your suppliers’ quality of work The work instructions should be well briefed, clear and define what sort of work ethics need to be followed to get timeline-based performance. There should be detailed supervision on the automated as well as the manually assigned tasks to the fleet members 5: Completion of the Task Under a well-structured fleet management program, the tasks operated by following the methods get you the desired outcomes in completing a task. With fleet maintenance software, you can record all the relevant information on the fleet assets allows managing well on your assets with key details like maintenance time, cost, and other valuable details. With details leading to better quality work, you can be well prepared for future issues coming into your fleet management and maintenance. 6: Analyze The Assets A major benefit of the fleet management system is the gathering of data on the services and operations. You can manage it well to find upon your lacking and work with an up-hand on the newer tasks. Some of the management solutions you can find through good analysis are: Scheduled Maintenance Records Task duration & reports Vehicle and fleet records Fleet personnel data records While developing a highly efficient fleet maintenance system, you need to follow the steps discussed in detail. It allows you to grasp the essential knowledge related to the fleet management system, which allows you to develop a highly successful and efficient fleet management system. To know more about a leading Fleet Maintenance System visit Hashstudioz
How Do I Build the Best but Cheapest Gaming Computer?
One that offers decent gaming performance in current titles should be a cost-effective gaming machine (PC) and will last you a few years before you think about upgrading. This will translate into a gaming PC that will now provide gaming experience with a high frame rate of 1080p and will provide playable gaming experience in the next 3-4 years. Since the gaming industry is heading toward 4 K gaming, even for a budget-oriented PC, a decent 1080p gaming experience should not be a concern. Given that we have chosen a slightly lower display resolution, both the GTX1060 and RX580 are decent low-cost GPU choices. A more future proof option will be GTX1070 or Vega56 if your budget allows it. All current titles can be run by a quad-core CPU, so a Ryzen 3 1500X or I3 8350 is a decent budget-oriented option, while Ryzen 2600X or i5 8400 are more future-proof choices Ram memory prices have dropped a bit, so depending on your budget, you can choose to get either 8 GB or 16 GB. For Ryzen, I must note that you should get at least 2933MHz certified memory, while the 2600MHz RAM modules are good enough for gaming with Intel. You can choose a cheap motherboard to be cost efficient, but I would prefer one with Intel Ethernet and a newer audio solution like Realtek 1220 because you are gaming. A marginally better network response than cheap network adapters is offered by Intel Ethernet, and the only better alternative is a Killer Ethernet adapter. For instance, an Asus Strix B350-F is a budget option for Ryzen 2600X that can provide the above features but is relatively cheap because it is being replaced by B450.0. Being cost-effective means that your case can bypass fancy led lighting, so having airflow is one important thing. For optimum airflow, get one that has a 12 cm fan in front and at the back, while the PSU is on the bottom of the case. Finally, cost-effective means you may want to miss getting an SSD, but I highly recommend that you (and maybe one or two games) get at least 256 GB SATA SSD for the machine. Beware, for maximum efficiency, have at least 20 percent of the SSD empty. Those with slightly deeper pockets can choose an NVME M.2 512GB SSD with a 2TB hard drive configuration. For hardcore gaming, laptop computers are not really suitable. Since their hardware is restricted to thermal and power requirements, they typically have variants of clocked desktop hardware. If possible, avoid buying a gaming laptop.
Quando se deve bloquear sites em sua empresa? Veja 8 fatores para considerar!
Se você possui uma empresa corporativa já deve ter ouvido falar sobre o bloqueio de sites em seus computadores para que os funcionários não se distraiam e só possam acessar os sites referentes ao trabalho. Esse é um assunto delicado, pois o bloqueio e a liberação de determinados sites em ambientes corporativos podem ou não levar em conta os interesses pessoais dos funcionários. Empresários e gestores de TI veem uma necessidade de restringir o acesso a determinados sites na hora do trabalho, mas nem sempre sabem como fazer isso. Por isso, a seguir nós mencionamos 8 fatores para considerar na hora de decidir se irá bloquear sites da sua empresa. Confira! 1 – Foco e produtividade dos funcionários As empresas que liberam todos os sites podem notar um problema muito comum em seus funcionários: a falta de foco que resulta em uma baixa da produtividade. A grande maioria de nós possui redes sociais e nos distraímos facilmente, principalmente se temos livre acesso a elas. Sem falar que muitas pessoas podem acabar mandando mensagem durante o dia e podemos nos distrair respondendo e resolvendo problemas pessoais. A produtividade é uma métrica muito importante dentro da empresa e ela deve ser levada em conta na hora de decidir se haverá o bloqueio de sites. O foco deve ser no desempenho da equipe, por isso se a produtividade está muito baixa, filtrar os sites que os colaboradores podem acessar pode ajudar a resolver. 2 – Consumo de banda larga O consumo de banda larga se torna excessivo quando a internet é totalmente liberada para os funcionários. A internet acaba sendo usada para fins pessoais como acesso a redes sociais, programas e jogos, além de alguns funcionários podem baixar programas para o computador da empresa. Algumas sessões da empresa precisam dos downloads, mas outras necessitam de uma rede mais estável que pode acabar sendo prejudicada se a internet estiver sendo usada para outros fins. O YouTube é um dos sites mais acessados pelos funcionários e um dos que mais consome banda larga, podendo deixar a internet mais lenta. Por isso, leve em conta como está o consumo da banda larga e se a internet anda lenta ou não, para definir se alguns sites serão bloqueados. 3 – Segurança da rede A segurança da rede também é um ponto muito importante e que deve ser considerado na decisão de bloquear sites. O livre acesso aos funcionários deixa a rede da empresa mais vulnerável a vírus e links maliciosos que são encontrados em downloads ou em sites não confiáveis. Nas redes sociais também é possível receber algum link malicioso e quando menos se espera, a rede da empresa pode ser prejudicada ou até mesmo hackeada. Muitas vezes, para evitar isso, algumas empresas permitem que os funcionários levem seus próprios computadores e dispositivos, mas recomendam que o antivírus esteja em dia. 4 – Maturidade Analise se a equipe de funcionários que você possui é madura. Se sim, será muito mais fácil de aceitar a sua decisão de bloquear os sites e não tentar burlar o sistema. A maturidade é algo muito importante para uma equipe e se a equipe se demonstrar comprometida com a produtividade, você não terá muitos problemas. 5 – Custos Os custos também devem ser considerados, afinal todos os demais tópicos refletem neles. As empresas que deixam o acesso liberado aos funcionários devem estar cientes que podem receber ataques ou serem hackeadas a qualquer momento e por isso devem estar preparadas para arcar com os custos de reparação. Além disso, acabam pagando mais com a banda larga. 6 – Satisfação dos funcionários Na hora de bloquear os sites, leve em conta que todos os funcionários precisam de alguns minutos ao longo do dia para descontrair e descansar, para que possam voltar ao trabalho com muito mais foco. Nem sempre o problema é liberar o acesso, mas sim impor limites. Se você preferir, estabeleça um horário no dia a dia em que o acesso ficará totalmente livre, como no horário do almoço, por exemplo. 7 – Particularidades de cada equipe Para definir os sites que cada grupo de funcionários poderá acessar, é preciso levar em conta o setor que atuam. A equipe de Marketing necessariamente precisará ter acesso às redes sociais para fazer as análises e implementar campanhas, por exemplo. Por isso, o ideal é descobrir as necessidades de cada equipe e estipular os sites liberados de acordo com isso. 8 – Analise É necessário analisar os dados da sua empresa diariamente. Analise quais foram os sites mais acessados pelos funcionários, confira se todas as restrições impostas estão sendo respeitadas. Compare os resultados com as análises de produtividade da equipe para ver se está dando resultados ou não. O contato próximo aos colaboradores te fará ter mais empatia e te ajudará a entender melhor como ajuda-los com o foco e a produtividade. https://www.ss3tecnologia.com.br/post/quando-se-deve-bloquear-sites
Principles regulating clinical trials worldwide
Clinical research training Clinical research training programs are designed for clinicians and scientists around the world. These research training programs provide advanced training in healthcare methods and research. The training often incorporates in-person seminars and dynamic workshops. It focuses on enhancing clinicians’ and staff skills, knowledge, and ability at every phase of the research, particularly for pre-clinical research phases. The training includes writing grant proposals and launching new projects for analyzing data and presenting their clinical results. . Take the Best Training in Clinical Research. Principles regulating clinical trials worldwide ● Obtaining clear, transparent, and informed consent from participants. ● Allowing participants to withdraw at any point of time from a clinical trial. ● The outcome of the clinical research should provide benefits to society without doing any harm to the participants who volunteered to participate in the clinical trial. Any unintended response to a drug or medical product should be considered an adverse reaction. Clinical trials are required to follow the following guidelines and more to ensure the safety of patients and efficacy of tests and treatments. However, stringent requirements may force clinical trials to shift to low-income and middle-income countries depriving the local population of the opportunity to benefit from international clinical research. ● ● A declaration of confirmation by the auditor that an audit has been conducted. ● The auditor should provide a written evaluation of the results of the audit. ● A written description of a clinical trial or study. ● Report of placebo or any investigational product if used in the clinical trial. ● The ethical and moral obligation to protect patients and reap clinical research benefits. . Take Clinical Research Course from the Best. The conclusions derived from the results of a clinical trial conducted worldwide generally apply to all study centers and countries. It increases the pace of drug development and facilitates the approval process of the tests and treatments in foreign markets. However, clinical trials face several challenges that they should overcome to ensure optimal conduct and coordinate clinical trial sites that operate under different regulations, technical, cultural, and political conditions. Clinical trial sponsors are responsible for obtaining consensus among clinical experts and regulatory agencies regarding fundamental questions that include a consistent diagnosis.
(April-2021)Braindump2go 200-201 PDF and 200-201 VCE Dumps(Q144-Q171)
QUESTION 144 Which action should be taken if the system is overwhelmed with alerts when false positives and false negatives are compared? A.Modify the settings of the intrusion detection system. B.Design criteria for reviewing alerts. C.Redefine signature rules. D.Adjust the alerts schedule. Answer: A QUESTION 145 What is the impact of false positive alerts on business compared to true positive? A.True positives affect security as no alarm is raised when an attack has taken place, resulting in a potential breach. B.True positive alerts are blocked by mistake as potential attacks affecting application availability. C.False positives affect security as no alarm is raised when an attack has taken place, resulting in a potential breach. D.False positive alerts are blocked by mistake as potential attacks affecting application availability. Answer: C QUESTION 146 An engineer needs to fetch logs from a proxy server and generate actual events according to the data received. Which technology should the engineer use to accomplish this task? A.Firepower B.Email Security Appliance C.Web Security Appliance D.Stealthwatch Answer: C QUESTION 147 Refer to the exhibit. Which technology generates this log? A.NetFlow B.IDS C.web proxy D.firewall Answer: D QUESTION 148 Which filter allows an engineer to filter traffic in Wireshark to further analyze the PCAP file by only showing the traffic for LAN 10.11.x.x, between workstations and servers without the Internet? A.src=10.11.0.0/16 and dst=10.11.0.0/16 B.ip.src==10.11.0.0/16 and ip.dst==10.11.0.0/16 C.ip.src=10.11.0.0/16 and ip.dst=10.11.0.0/16 D.src==10.11.0.0/16 and dst==10.11.0.0/16 Answer: B QUESTION 149 Which tool provides a full packet capture from network traffic? A.Nagios B.CAINE C.Hydra D.Wireshark Answer: D QUESTION 150 A company is using several network applications that require high availability and responsiveness, such that milliseconds of latency on network traffic is not acceptable. An engineer needs to analyze the network and identify ways to improve traffic movement to minimize delays. Which information must the engineer obtain for this analysis? A.total throughput on the interface of the router and NetFlow records B.output of routing protocol authentication failures and ports used C.running processes on the applications and their total network usage D.deep packet captures of each application flow and duration Answer: C QUESTION 151 Refer to the exhibit. What is depicted in the exhibit? A.Windows Event logs B.Apache logs C.IIS logs D.UNIX-based syslog Answer: D QUESTION 152 Which technology should be used to implement a solution that makes routing decisions based on HTTP header, uniform resource identifier, and SSL session ID attributes? A.AWS B.IIS C.Load balancer D.Proxy server Answer: B QUESTION 153 An organization has recently adjusted its security stance in response to online threats made by a known hacktivist group. What is the initial event called in the NIST SP800-61? A.online assault B.precursor C.trigger D.instigator Answer: B QUESTION 154 Which NIST IR category stakeholder is responsible for coordinating incident response among various business units, minimizing damage, and reporting to regulatory agencies? A.CSIRT B.PSIRT C.public affairs D.management Answer: D QUESTION 155 Which incidence response step includes identifying all hosts affected by an attack? A.detection and analysis B.post-incident activity C.preparation D.containment, eradication, and recovery Answer: D QUESTION 156 Which two elements are used for profiling a network? (Choose two.) A.session duration B.total throughput C.running processes D.listening ports E.OS fingerprint Answer: DE QUESTION 157 Which category relates to improper use or disclosure of PII data? A.legal B.compliance C.regulated D.contractual Answer: C QUESTION 158 Which type of evidence supports a theory or an assumption that results from initial evidence? A.probabilistic B.indirect C.best D.corroborative Answer: D QUESTION 159 Which two elements are assets in the role of attribution in an investigation? (Choose two.) A.context B.session C.laptop D.firewall logs E.threat actor Answer: AE QUESTION 160 What is personally identifiable information that must be safeguarded from unauthorized access? A.date of birth B.driver's license number C.gender D.zip code Answer: B QUESTION 161 In a SOC environment, what is a vulnerability management metric? A.code signing enforcement B.full assets scan C.internet exposed devices D.single factor authentication Answer: C QUESTION 162 A security expert is working on a copy of the evidence, an ISO file that is saved in CDFS format. Which type of evidence is this file? A.CD data copy prepared in Windows B.CD data copy prepared in Mac-based system C.CD data copy prepared in Linux system D.CD data copy prepared in Android-based system Answer: C QUESTION 163 Which two elements of the incident response process are stated in NIST Special Publication 800-61 r2? (Choose two.) A.detection and analysis B.post-incident activity C.vulnerability management D.risk assessment E.vulnerability scoring Answer: AB QUESTION 164 Refer to the exhibit. What does this output indicate? A.HTTPS ports are open on the server. B.SMB ports are closed on the server. C.FTP ports are open on the server. D.Email ports are closed on the server. Answer: A QUESTION 165 Which metric should be used when evaluating the effectiveness and scope of a Security Operations Center? A.The average time the SOC takes to register and assign the incident. B.The total incident escalations per week. C.The average time the SOC takes to detect and resolve the incident. D.The total incident escalations per month. Answer: C QUESTION 166 A developer is working on a project using a Linux tool that enables writing processes to obtain these required results: - If the process is unsuccessful, a negative value is returned. - If the process is successful, 0 value is returned to the child process, and the process ID is sent to the parent process. Which component results from this operation? A.parent directory name of a file pathname B.process spawn scheduled C.macros for managing CPU sets D.new process created by parent process Answer: D QUESTION 167 An engineer discovered a breach, identified the threat's entry point, and removed access. The engineer was able to identify the host, the IP address of the threat actor, and the application the threat actor targeted. What is the next step the engineer should take according to the NIST SP 800-61 Incident handling guide? A.Recover from the threat. B.Analyze the threat. C.Identify lessons learned from the threat. D.Reduce the probability of similar threats. Answer: D QUESTION 168 Refer to the exhibit. What is shown in this PCAP file? A.Timestamps are indicated with error. B.The protocol is TCP. C.The User-Agent is Mozilla/5.0. D.The HTTP GET is encoded. Answer: A QUESTION 169 What is a difference between tampered and untampered disk images? A.Tampered images have the same stored and computed hash. B.Tampered images are used as evidence. C.Untampered images are used for forensic investigations. D.Untampered images are deliberately altered to preserve as evidence Answer: B QUESTION 170 Drag and Drop Question Drag and drop the definition from the left onto the phase on the right to classify intrusion events according to the Cyber Kill Chain model. Answer: QUESTION 171 Drag and Drop Question Drag and drop the elements from the left into the correct order for incident handling on the right. Answer: 2021 Latest Braindump2go 200-201 PDF and 200-201 VCE Dumps Free Share: https://drive.google.com/drive/folders/1fTPALtM-eluHFw8sUjNGF7Y-ofOP3s-M?usp=sharing
Good pharmacovigilance practice guidelines
The incredible pharmacovigilance practice rules include: •All principles subject to patients, clinical benefits specialists, and general prosperity on the sole piece of safety should be met. •All the affiliation people should be locked in with assistance of the watchfulness structure subject to the endeavor of ownership and commitment in regards to the best level of significant worth according to their individual obligations. •The higher organization levels should have extraordinary activity qualities and ought to be good for driving the gathering toward achieving the above-shaped objectives. •All people from the gathering should try toward improving the quality example of the medicine. •The resources and tasks should be coordinated so much that the cycles are proactive, steady, planned, danger proportionate, and co-usable lead of pharmacovigilance training •An overall significantly profitable and co-employable similarity should be kept up by all divisions related to the pharmacovigilance office. Especially with the advancing division, co-action should be at the apex. •Good relations and co-action should moreover be developed with the individual trained professionals and general prosperity relationship according to proper legal courses of action. The necessity for pharmacovigilance is completely established on the prosperity profile of the prescriptions and therapeutic things that are eaten up by the patients. With the present rapidly creating advancement, prescription is moreover advancing. The new progressing infections need a proper fix with high restrictions of safety. This is making the pharmacovigilance cooperation more critical now than some other time. Thusly, for an unrivaled a fair pharmacovigilance office, the above rules should be clung to. The standard inspirations to stick to these guidelines include: •Emerging security issues related to the harmony of risks and benefits of the prescriptions and helpful thing. •New and dark information that appears from the specific advancing endorsement holders. •Procedures appropriate to pharmacovigilance may prompt new information achieving the reviving of the collaboration without assistance from any other person. •On-going or new clinical fundamentals may prompt new indications or troublesome effects of the prescriptions, making the connection need invigorating routinely. The pioneers and higher specialists in the medication world have a phenomenal plan to consider while considering extraordinary pharmacovigilance training. The threat versus advantage extent limit of any prescription or helpful treatment is one of their once-over's powerhouses. Thus the degree of good pharmacovigilance practices consolidates relationship with the solution or prescription, abuse and maltreatment of the drug or medication, clinical missteps, nonappearance of ampleness, troublesome reactions, and incredible co-movement.
Top 10 Amazing Tricks To Get The Most Out Of Your Attendance Management Software
Originally Published At Techimply April 19, 2021 If you are an existing user of the attendance management system or if you are planning to get one for yourself. We are here with the top 10 amazing tricks to get the most of the output from your attendance management system. Let us have a look over all.  Setting clear expectations for employees It is helpful in drafting a clear attendance policy listing the rules and expectations as the first step to effective attendance management. It helps to run the business efficiently and reduce the unscheduled work. The policy should be capable of requesting the time off and the consequences of not following the attendance procedures. Before you draft the policy, you have to keep in mind the company culture to ensure consistency. Talking to employees, listening to expectations and ensuring that they fully understand the policy is a major thing.  Combining attendance and payroll Managing the employee attendance accurately is important for the payroll. When there are errors in the attendance data, you may end up either overpaying or underpaying the payroll. Analyzing the attendance data manually to process the payroll can cause more mistakes and can also be time consuming, especially when the workforce is large and is at different locations. It can be helpful to integrate the HR software with payroll software. HR software calculates the working hours, loss of pay and overtime, making the payroll easier, accurate and more transparent.  Encouraging employees to manage attendance Employees should be allowed to access the attendance and time off data at convenience. It reduces the questions of the employees regarding the HR department and also plans the work and vacations. Additionally, one should make the attendance policy accessible through the employee self-service portal. Using this information at disposal, the employees feel like they have more knowledge and control of the work lives. This can boost motivation and ultimately reduce turnover.  Be flexible  Rigid attendance policies can lead the employees to dislike their job and that can reduce morale. When employees are given little time off, it can lead to unscheduled absenteeism and the company’s bottom line may suffer. Hence it is essential to make the attendance policy flexible. It is important to consider and respect the concerns of employees. However, you should not allow things to get unbiased. To provide flexibility, you can give remote work options to the employees when they are not physically present at the workplace.  Using attendance tracker Manual management of attendance was in yesteryears. Using the attendance tracker you can automate every aspect of the attendance management. The inconsistencies can be prevented as the attendance tracker can be easily integrated with the company’s other devices. Employees can log their working hours while working remotely using the suitable IP and geo-restrictions.  Self service The employees should be allowed to take control over their attendance records through the self-service program. Such a program allows the team to be able to review the time purchases and can also request changes to confirm accuracy.  They will also be allowed to ask for time off. The staff members can check the remaining PTO balances at the time they like, instead of asking the HR manager again and again. This feature is very useful because when the employee plans a vacation or is not able to come due to any family problems.  Go mobile If the employees work from home, from multiple offices or from the client locations, opt for the attendance tracking system that is easy to take on the go. Using the mobile app, the employees can clock in and out regardless of their place of working. Even if they don’t work from multiple locations, a mobile app can be useful in tracking the attendance more quickly. Also you never have to worry about installing the extra equipment such as a wall mounted time clock.  Limit access Even if you trust your employees, you need to ensure that they are only tracking their office time and no one else. It helps you to know that no one tries to take advantage of you. In such a case, opt for the system that allows to limit the clock access. Generally the software users are provided with two options: Wi-Fi access restrictions ensure that the employees can only clock in and out if the mobile device is connected to the company’s internet network connection.  Limiting the access through geolocation makes sure that the employees can clock in and out when they are within a specific range of distance from the office.  Biometric The integration of biometric devices with the attendance management software allows the employees to track the attendance with the touch of finger using the biometric scanner. It is easy to make it convenient for employees but one of its drawbacks is inability to scan the figure if any dirt or moisture is present on it.  Using data security feature The entries in the paper, manual registers can be easily tampered with and the reports on the spreadsheets are equally exposed to manipulation or destruction. The paperless operations are tamper-proof especially if the attendance management software is able to provide the role based access. One of the best features of the attendance management software india is security of the data with multiple layers of security and encryption.  Conclusion If you have already used the attendance management software, you may be aware of a few of the benefits of using it but if you are still following the manual method of attendance, we suggest you take a step forward and move towards using the automated attendance management system.
Clinical trial phases
Clinical trials are a type of research conducted to study new tests, treatments, and drugs and evaluate their outcomes, side effects, and efficacy on human health. There are various medical interventions, including drugs, biological products, radiological procedures, devices, behavioral treatments, surgical procedures, and preventive care in which people volunteer to take part. Take the Best Training in Clinical Research. Clinical trial phases Biomedical, clinical trials include the following four clinical research phases: ● Phase I of clinical trials usually studies new drugs for the first time in a small group of people to evaluate a safe dosage range and identify side effects. ● Phase II of clinical trials studies test treatments that were found safe in phase I of clinical trials. However, phase II is conducted on a larger group of human subjects for monitoring any adverse effects. ● Phase III of clinical trials is conducted in different regions and countries and on larger populations. Phase III is the step conducted right before a new treatment or drug is approved. ● Phase IV of clinical trials is conducted after a country approves, but there is still a need for further testing efficacy in a larger population over a longer timeframe. . Take Clinical Research Course from the Best. There are various guidelines outlined by different international and national organizations for ensuring careful design, review, and completion of the process. Clinical trials require approval before they can even begin. People of all ages, including children, can volunteer to participate in clinical trials. However, various guidelines direct the participation of people in clinical trials. These guidelines can relate to underlying health conditions, side effects from other drugs, and so on.