Gout is characterized by recurrent episodes of acute arthritis with sudden expression of pain in the middle of the night and red swelling of the joints, mainly in the thumb during the episode of inflammation. Because of such symptoms, helping patients relieve pain in gout arthritis is essential in treatment.
1. What is gout?
Gout (gout) is a disorder of the metabolism of purines in the kidneys, causing the kidneys to lose the ability to filter uric acid in the blood. This is the cause of uric acid accumulation over time, forming small crystals concentrated in the joints, causing symptoms of inflammation, swelling and pain for patients.
2. Causes of gout
As mentioned, gout occurs due to an increase and accumulation of uric acid in the joints that causes painful swelling in the patient. So, all the causes of increasing blood uric acid can cause gout such as:
You are concerned about the risk of the disease see also: Diabetes treatment
Use many foods containing purines such as: organs, shrimp, crab, egg yolks, mushrooms;
Increased breakdown of cellular nucleoproteins;
Increased synthesis of endogenous purines;
Reducing uric acid excretion due to decreased glomerular filtration rate or decreased uric acid breakdown in feces by bacteria;
Genetic factors: Children have a 20% higher rate of gout than normal if their parents have gout;
Due to gender: Men have a higher rate of gout than women, however menopausal women can also get it;
Abuse of niacin supplements and vitamins, lead poisoning causes uric acid metabolism disorders;
Due to obesity or metabolic disorders, diabetes, kidney disease.
Obesity can be a contributing factor to gout
3. How to relieve pain in patients with gout arthritis?
With gout acute arthritis the goal of treatment is to eliminate acute pain and swelling in the affected joints. That's why medications you can take include:
Nonsteroidal anti-inflammatory and analgesic drugs: Indomethacin, mobic, meloxicam, felden, ...;
Colchicine: If the patient does not respond to nonsteroidal drugs, colchicine can be used instead. Although it is not an analgesic, it is classified as an anti-gout when small doses of chronic gout and high doses can be used to deal with acute gout. The drug is most effective at the first 12 hours of symptom onset. However, it should be noted that the drug has side effects such as nausea, diarrhea, abdominal pain or poisoning at high doses;
Corticosteroids: Prednisone, dexamethasone, solumedrol can be used to treat an acute gout attack if the patient is not responsive to steroids and colchicine. It relieves pain and inflammation fairly quickly, but needs to be monitored by a doctor and administered in reduced doses over 7-10 days. The drug is contraindicated to people with peptic ulcers.
Besides, patients also need to comply with treatment regimen and follow a diet with alcohol, red meats, animal organs, and seafood. Gout very often recurs, so patients also need to periodically see a doctor to monitor the uric acid index in order to early prognosis for recurrent gout attacks.
In fact, gout is quite common in Vietnam, but not all people have sufficient knowledge about the disease, along with the habit of using drugs arbitrarily will lead to more serious disease. Some medicines that can increase or worsen your risk of gout include:
Steroids: Although it is a very quick pain reliever and swelling medication, corticosteroids are also a "double-edged sword" that in the long run can cause dangerous complications such as hypertension, cataracts, diabetes and gout. Mechanism of corticosteroids when entering the body will compete with secretion with uric acid in the renal tubules, causing the amount of uric acid of the patient to increase again, inadvertently aggravating the condition of gout.
Aspirin: A classic drug belonging to the group of nonsteroidal anti-inflammatory drugs that was popular in the past to treat arthritis. However, with the advent of other more effective nonsteroidal drugs, aspirin became less and less used. In addition, low-dose aspirin is also the cause of secondary gout.
Diuretics: All diuretics (except spironolactone) affect the body's excretion of uric acid, causing an increase in uric acid in the blood leading to gout. Therefore, gout patients taking diuretics need to monitor the concentration of uric acid in the blood to detect early manifestations of acute gout attacks.
Gout patients taking diuretics need to monitor blood uric acid levels to detect early symptoms of acute gout attacks.
The pain caused by arthritis in gout patients greatly affects the quality of life and work of the patient, so the use of pain relief is very important. Patients should see their doctor for specific advice.