Subcutaneous biologic drugs and affiliated technologies market is projected to be worth over USD 180 billion by 2030

Roots Analysis has done a detailed report on Subcutaneous Biologics, Technologies and Drug Delivery Systems (3rd Edition), 2020-2030 covering key aspects of the industry and identifying future growth opportunities

To order this 530+ page report, which features 160+ figures and 190+ tables, please visit this - https://www.rootsanalysis.com/reports/view_document/subcutaneous-biologics-delivery/314.html

Key Market Insights
§ Eminent representatives from biopharmaceutical companies confirm the rising interest in the concept of subcutaneous drug delivery, highlighting some of the key drivers and upcoming trends in this domain
§ More than 100 subcutaneous biologics have been approved and over 350 such drug candidates are being evaluated in the clinical stages of development, for the treatment of a wide variety of disease indications
§ Antibodies and protein therapeutics represent the majority of subcutaneous biologics that are available / under investigation, designed for use against various therapeutic areas and having different dosing regimens
§ Advances in drug delivery have led to the development of novel technology platforms, enabling the administration of highly viscous formulations, and supporting the development of subcutaneous dosage forms
§ Several technology developers have out-licensed their proprietary platforms to pharmaceutical companies in order to enable them to develop subcutaneous formulations of their approved / pipeline products
§ The increasing interest in this field is reflected in the yearly growth in partnership activity, including a number of licensing and product development deals related to subcutaneous formulations of various drug candidates
§ There are several new and innovative drug delivery systems that facilitate subcutaneous administration; we identified over 300 such systems that are presently available / under development
§ With several self-medication enabling devices, such as wearable injectors and autoinjectors, available in the market, developers are actively differentiating their offerings by incorporating advanced, patient-friendly features
§ The market is anticipated to be worth over USD 180 billion in 2030; the projected opportunity is likely to be distributed across various types of molecules that are developed / being developed for different disease indications
§ Pre-filled syringes continue to dominate the current market of subcutaneous drug delivery systems; technology developers are expected to continue relying on licensing agreements as their primary source of revenues333

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Table of Contents

1.1. Scope of the Report
1.2. Research Methodology
1.3. Chapter Outlines


3.1. Chapter Overview
3.2. Types of Therapeutic Molecules
3.3. Biologically Derived Therapeutics
3.3.1. Types of Products
3.3.2. Routes of Administration and Formulations
3.3.3. Subcutaneous Formulations Approaches in Subcutaneous Delivery of Biologics Reformulation Differing Potencies Novel Technologies Method of Subcutaneous Administration Advantages of Subcutaneous Administration Limitations of Subcutaneous Administration

3.4. Regulatory Considerations
3.4.1. Medical Devices
3.4.2. Drug Device Combination Products

3.5. Future Perspectives

4.1. Chapter Overview
4.2. Subcutaneous Administration of Biologics
4.3. Subcutaneous Biologics: List of Approved Drugs
4.3.1. Analysis by Approval Year
4.3.2. Analysis by Type of Pharmacological Molecule
4.3.3. Analysis by Target Therapeutic Area
4.3.4. Analysis by Type of Formulation
4.3.5. Analysis by Dosing Frequency
4.3.6. Analysis by Dosage Form
4.3.7. Key Players: Analysis by Number of Drugs Approved

4.4. Subcutaneous Biologics: List of Clinical-Stage Drug Candidates
4.4.1. Analysis by Phase of Development
4.4.2. Analysis by Type of Pharmacological Molecule
4.4.3. Analysis by Target Therapeutic Area
4.4.4. Analysis by Dosing Frequency
4.4.5. Key Players: Analysis by Number of Drug Candidates in Trials

5.1. Chapter Overview
5.2. Subcutaneous Biologics: Leading Drugs by Annual Sales

5.3. Case Studies
5.3.1. HUMIRA® (AbbVie, Eisai) Drug Overview
5. 3.1.2. Development History
5. 3.1.3. Target Indications and Dosage Forms
5. 3.1.4. Historical Sales

5.3.2. Enbrel® (Amgen, Pfizer, Takeda Pharmaceutical) Overview
5. 3.2.2. Development History
5. 3.2.3. Target Indications and Dosage Forms
5. 3.2.4. Historical Sales

5.3.3. RITUXAN® / MabThera® (Biogen, Roche, Chugai Pharmaceutical) Overview
5. 3.3.2. Development History
5. 3.3.3. Target Indications and Dosage Forms
5. 3.3.4. Historical Sales
5. 3.3.5. ENHANZE™ Technology (Halozyme Therapeutics)
5. 3.3.6. Advantages of Subcutaneous RITUXAN® / MabThera® Over Intravenous RITUXAN® / MabThera®

5.3.4. Herceptin® (Roche, Chugai Pharmaceutical) Overview
5. 3.4.2. Development History
5. 3.4.3. Target Indications and Dosage Forms
5. 3.4.4. Historical Sales
5. 3.4.5. ENHANZE™ Technology (Halozyme Therapeutics)
5. 3.4.6. Advantages of Subcutaneous Herceptin® Over Intravenous Herceptin®
5. 3.4.7. Herceptin® - Large Volume Wearable Injector Combination Product

5.3.5. Neulasta® (Amgen, Kyowa Hakko Kirin) Overview Development History Target Indications and Dosage Forms Historical Sales

6.1. Chapter Overview
6.2. Subcutaneous Formulation Technologies: List of Technology Developers
6.2.1. Analysis by Year of Establishment
6.2.2. Analysis by Company Size
6.2.3. Analysis by Geographical Location
6.3. Subcutaneous Formulation Technologies: List of Technologies
6.3.1. Analysis by Type of Pharmacological Molecule
6.3.2. Analysis by Route of Administration
6.3.3. Analysis by Advantage(s) Offered

7.1. Chapter Overview
7.2. Subcutaneous Formulation Technology Developers: Competitive Landscape
7.2.1. Methodology
7.2.2. Three-Dimensional Bubble Analysis based on Supplier Power, Pipeline Strength and Primary Advantage(s)

7.3. Subcutaneous Formulation Technology Developers: Benchmark Analysis
7.3.1. Methodology
7.3.2. North America
7.3.3. Europe

8.1. Chapter Overview
8.2. Adocia
8.2.1. Company Overview
8.2.2. Technology Overview BioChaperone® Technology
8.2.3. Product Portfolio
8.2.4. Financial Performance
8.2.5. Recent Developments and Future Outlook

8.3. Ajinomoto Althea
8.3.1. Company Overview
8.3.2. Technology Overview Crystalomics® Formulation Technology
8.3.3. Product Portfolio
8.3.4. Financial Performance
8.3.5. Recent Developments and Future Outlook

8.4. Arecor
8.4.1. Company Overview
8.4.2. Technology Overview Arestat™ Technology
8.4.3. Product Portfolio
8.4.4. Recent Developments and Future Outlook

8.5. Alteogen
8.5.1. Company Overview
8.5.2. Technology Overview Hybrozyme Technology
8.5.3. Product Portfolio
8.5.4. Recent Developments and Future Outlook

8.6. Ascendis Pharma
8.6.1. Company Overview
8.6.2. Technology Overview TransCon Technology
8.6.3. Product Portfolio
8.6.4. Financial Performance
8.6.5. Recent Developments and Future Outlook

8.7. Avadel Pharmaceuticals
8.7.1. Company Overview
8.7.2. Technology Overview Medusa™ Technology
8.7.3. Product Portfolio
8.7.4. Financial Performance
8.7.5. Recent Developments and Future Outlook

8.8. Camurus
8.8.1. Company Overview
8.8.2. Technology Overview FluidCrystal® Injection Depot Technology
8.8.3. Product Portfolio
8.8.4. Financial Performance
8.8.5. Recent Developments and Future Outlook

8.9. Creative BioMart
8.9.1. Company Overview
8.9.2. Technology Overview High Concentration Formulation Technology
8.9.3. Product Portfolio
8.9.4. Recent Developments and Future Outlook

8.10. Creative Biolabs
8.10.1. Company Overview
8.10.2. Technology Overview Long-Acting Injectable Technology
8.10.3. Product Portfolio
8.10.4. Recent Developments and Future Outlook

8.11. DURECT
8.11.1. Company Overview
8.11.2. Technology Overview SABER® Platform CLOUD™ PLATFORM
8.11.3. Product Portfolio
8.11.4. Financial Performance
8.11.5. Recent Developments and Future Outlook

8.12. Eagle Pharmaceuticals
8.12.1. Company Overview
8.12.2. Technology Overview Unnamed Technology
8.12.3. Product Portfolio
8.12.4. Financial Performance
8.12.5. Recent Developments and Future Outlook

8.13. Halozyme Therapeutics
8.13.1. Company Overview
8.13.2. Technology Overview ENHANZE® Technology
8.13.3. Product Portfolio
8.13.4. Financial Performance
8.13.5. Recent Developments and Future Outlook

8.14. MedinCell
8.14.1. Company Overview
8.14.2. Technology Overview BEPO® Technology
8.14.3. Product Portfolio
8.14.4. Recent Developments and Future Outlook

8.15. Xeris Pharmaceuticals
8.15.1. Company Overview
8.15.2. Technology Overview XeriJect™ Technology XeriSol™ Technology
8.15.3. Product Portfolio
8.15.4. Recent Developments and Future Outlook

8.16. Serina Therapeutics
8.16.1. Company Overview
8.16.2. Technology Overview POZ™ Drug Delivery Technology
8.16.3. Product Portfolio
8.16.4. Recent Developments and Future Outlook

9.1. Chapter Overview
9.2. Partnership Models
9.3. Subcutaneous Formulation Technologies: Partnerships and Collaborations
9.3.1. Analysis by Year of Partnership
9.3.2. Analysis by Type of Partnership
9.3.3. Most Active Players: Analysis by Number of Partnerships
9.3.4. Regional Analysis
9.3.5. Intercontinental and Intracontinental Agreements

10.1. Chapter Overview
10.2. Different Types of Subcutaneous Drug Delivery Systems
10.3. Subcutaneous Drug Delivery Systems: Overall Market Landscape
10.3.1. Large Volume Wearable Injectors Overview Current Market Landscape of Devices for Non-insulin Biologics Analysis by Stage of Development Analysis by Type of Device Analysis by Type of Dose Administered Analysis by Volume / Storage Capacity Analysis by Usability Analysis by Mode of Injection Analysis by Mechanism of Action Most Active Players: Analysis by Number of Devices Product Competitiveness Analysis Current Market Landscape of Devices for Insulin Analysis by Stage of Development Analysis by Type of Device Analysis by Volume / Storage Capacity Analysis by Usability Analysis by Availability of Integrated CGM / BGM System Most Active Players: Analysis by Number of Devices Product Competitiveness Analysis

10.3.2. Autoinjectors Overview Current Market Landscape Analysis by Usability Analysis by Type of Primary Container Analysis by Volume / Storage Capacity Analysis by Type of Dose Analysis by Actuation Mechanism Most Active Players: Analysis by Number of Devices Product Competitiveness Analysis Drug Device Combination Products

10.3.3. Pen Injectors Overview Current Market Landscape Analysis by Usability Analysis by Volume / Storage Capacity Analysis by Type of Dose Most Active Players: Analysis by Number of Devices Drug Device Combination Products

10.3.4. Needle-Free Injection Systems Overview Current Market Landscape Analysis by Stage of Development Analysis by Volume / Storage Capacity Analysis by Usability Analysis by Actuation Mechanism Most Active Players: Analysis by Number of Devices Product Competitiveness Analysis

10.3.5. Drug Reconstitution Delivery Systems Overview Current Market Landscape Analysis by Usability Analysis by Type of Device Analysis by Type of Drug Container Most Active Players: Analysis by Number of Devices

10.3.6. Prefilled Syringes Overview Current Market Landscape Analysis by Barrel Fabrication Material Analysis by Number of Barrel Chambers Analysis by Type of Needle System Analysis by Volume / Storage Capacity Most Active Players: Analysis by Number of Devices Product Competitiveness Analysis Drug Device Combination Products

10.3.7. Implants Overview Current Market Landscape Analysis by Stage of Development Analysis by Target Therapeutic Area Analysis by Implant Material Analysis by Treatment Duration Most Active Players: Analysis by Number of Devices

11.1. Chapter Overview
11.2. Comparison of SWOT Factors
11.2.1. Strengths
11.2.2. Weaknesses
11.2.3. Opportunities
11.2.4. Threats

12.1. Chapter Overview
12.2. Subcutaneous Biologics Market
12.2.1. Forecast Methodology and Key Assumptions
12.2.2. Overall Subcutaneous Biologics Market, 2020-2030 Subcutaneous Biologics Market, 2020-2030:Distribution by Phase of Development Subcutaneous Biologics Market, 2020-2030:Distribution by Type of Pharmacological Molecule Subcutaneous Biologics Market, 2020-2030:Distribution by Target Therapeutic Area Subcutaneous Biologics Market, 2020-2030:Distribution by Key Geographical Regions

12.3. Subcutaneous Drug Delivery Systems Market
12.3.1. Device Type 1: Large Volume Wearable Injectors Forecast Methodology and Key Assumptions Global Large Volume Wearable Injectors Market for Non-Insulin Drugs, 2020-2030 Global Large Volume Wearable Injectors Market for Non-Insulin Drugs: Distribution by Type of Device, 2020-2030 Global Large Volume Wearable Injectors Market for Non-Insulin Drugs: Distribution by Usability, 2020-2030 Global Large Volume Wearable Injectors Market for Non-Insulin Drugs: Distribution by Target Therapeutic Area, 2020-2030 Global Large Volume Wearable Injectors Market for Non-Insulin Drugs: Distribution by Key Geographical Regions, 2020-2030 Global Large Volume Wearable Injectors Market for Insulin , 2020-2030 Global Large Volume Wearable Injectors Market for Insulin: Distribution by Type of Device, 2020-2030 Global Large Volume Wearable Injectors Market for Insulin: Distribution by Usability, 2020-2030 Global Large Volume Wearable Injectors Market for Insulin: Distribution by Key Geographical Regions, 2020-2030

12.3.2. Device Type 2: Autoinjectors Forecast Methodology and Key Assumptions Global Autoinjectors Market, 2020-2030 Global Autoinjectors Market: Distribution by Usability, 2020-2030 Global Autoinjectors Market: Distribution by Type of Pharmacological Molecule, 2020-2030 Global Autoinjectors Market: Distribution by Key Geographical Regions, 2020-2030

12.3.3. Device Type 3: Prefilled Syringes Forecast Methodology and Key Assumptions Global Prefilled Syringes Market, 2020-2030 Global Prefilled Syringes Market: Distribution by Type of Syringe Barrel Material, 2020-2030 Global Prefilled Syringes Market: Distribution by Type of Chamber System, 2020-2030 Global Prefilled Syringes Market: Distribution by Type of Pharmacological Molecule, 2020-2030 Global Prefilled Syringes Market: Distribution by Target Therapeutic Area, 2020-2030 Global Prefilled Syringes Market: Distribution by Key Geographical Regions, 2020-2030

12.3.4. Device Type 4: Needle-Free Injection Systems Forecast Methodology and Key Assumptions Global Needle-Free Injection Systems Market, 2020-2030 Global Needle-Free Injection Systems Market: Distribution by Usability, 2020-2030 Global Needle-Free Injection Systems Market: Distribution by Actuation Mechanism, 2020-2030 Global Needle-Free Injection Systems Market: Distribution by Target Therapeutic Area, 2020-2030 Global Needle-Free Injection Systems Market: Distribution by Key Geographical Regions, 2020-2030

12.3.5. Device Type 5: Novel Drug Reconstitution Systems Forecast Methodology and Key Assumptions Global Novel Drug Reconstitution Systems Market, 2020-2030

12.4. Subcutaneous Formulation Technologies Market
12.4.1. Subcutaneous Formulation Technologies Market: Distribution by Upfront and Milestone Payments, 2020-2030


14.1. Chapter Overview

14.2. Lindy Biosciences
14.2.1. Company Snapshot
14.2.2. Interview Transcript: Deborah Bitterfield, Chief Executive Officer and Founder

14.3. Oval Medical Technologies
14.3.1. Company Snapshot
14.3.2. Interview Transcript: Matthew Young, Chief Technology Officer and Founder

14.4. Xeris Pharmaceuticals
14.4.1. Company Snapshot
14.4.2. Interview Transcript: Steve Prestrelski, Chief Scientific Officer and Founder; Hong Qi, Vice President, Product Development; and Scott Coleman, Sr. Scientist Formulation)

14.5. DALI Medical Devices
14.5.1. Company Snapshot
14.5.2. Interview Transcript: David Daily, Chief Executive Officer and Co-Founder

14.6. Excelse Bio
14.6.1. Company Snapshot
14.6.2. Interview Transcript: Michael Reilly, Chief Executive Officer and Co-Founder

14.7. i-novion
14.7.1. Company Snapshot
14.7.2. Interview Transcript: Poonam R Velagaleti, Co-Founder

14.8. Enable Injections
14.8.1. Company Snapshot
14.8.2. Interview Transcript: Michael Hooven, Chief Executive Officer

14.9. Immunovaccine Technologies
14.9.1. Company Snapshot
14.9.2. Interview Transcript: Frederic Ors, Chief Executive Officer

14.10. Portal Instruments
14.10.1. Company Snapshot
14.10.2. Interview Transcript: Patrick Anquetil, Chief Executive Officer

14.11. Elcam Medical
14.11.1. Company Snapshot
14.11.2. Interview Transcript: Menachem Zucker, Vice President and Chief Scientist

14.12. West Pharmaceutical Services
14.12.1. Company Snapshot
14.12.2. Interview Transcript: Tiffany H Burke, Director, Global Communications and Graham Reynolds, Vice President and General Manager, Global Biologics

14.13. MedinCell
14.13.1. Company Snapshot
14.13.2. Interview Transcript: David Heuzé, Communication Leader



Contact Details
Gaurav Chaudhary
+1 (415) 800 3415
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Tổ yến thực chất là nước bọt của một số loài chim yến có khả năng nhả nước dãi xây tổ. Nói vậy để các bạn hiểu không phải chim yến nào cũng có thể đắp tổ bằng nước bọt. Và ở Việt Nam thì nổi tiếng về yến sào đặc biệt là yến sào có nguồn gốc từ Khánh Hòa. Yến sào được chế biến thành nhiều món ăn tẩm bổ như yến chưng, cháo yến,... Yến chưng có nhiều thành phần đinh dưỡng như protein, nhiều axit amin, vitamin, các khoáng chất vô cùng có lợi cho sức khỏe. Mỗi ngày bổ sung 1 lượng nhỏ yến sào cung cấp năng lượng cho các hoạt động cơ thể, tăng cao sức đề kháng. Không chỉ đối với người già hay trẻ em mà ngay cả với phụ nữ mang thai thì món yến chưng cùng với nhiều nguyên liệu khác cũng mang tới nhiều công dụng tốt. Bà bầu nên ăn yến vào tháng thứ mấy ? và ăn liều lượng như thế nào để đảm bảo dưỡng chất trong quá trình mang thai. Hãy cũng tìm hiểu thông tin dưới đây nhé. Cũng giống như các loại thực phẩm khác, tổ yến dù có nhiều lợi ích cho sức khỏe con người nhưng cũng cần phải chú ý tới cách chế biến và cách sử dụng. Bà bầu không nên ăn yến vào những thời gian đầu mang thai , lúc này cơ thể còn yếu thai nhi cũng mới hình thành cho nên khi nạp vào cơ thể thực phẩm cần phải cẩn trọng tránh gây một số tác dụng phụ. Khi qua giai đoạn ốm nghén mấy tháng đầu thì có thể dùng yến chưng được. Tổ yến nên chưng bằng nồi chưng yến chuyên dụng để giữ được lượng dinh dưỡng tối đa của yến, ngoài ra việc cho thêm nguyên liệu khác cũng cần lưu ý. Theo các chuyên gia, từ tháng thứ 4 trở đi bà bầu có thể ăn yến được rồi, lượng yến ăn mỗi ngày sẽ không nhiều, các chị em có thể ăn cách nhật hoặc 1 tuần ăn 3 - 4 lần cũng được. Tuy nhiên mỗi 1 lần ăn không quá nhiều vì yến sào rất nhiều chất. Chúng ta nên bồi bổ dinh dưỡng từ từ chứ không nên ăn 1 lúc quá nhiều sẽ không tốt cho cơ thể. Yến giúp mẹ bầu tăng sức đề kháng, phòng ngừa một số bệnh, cung cấp lượng dưỡng chất cho cả mẹ và con. Chế biến yến sào có rất nhiều cách, nhưng đa phần mọi người hay làm yến chưng kèm những nguyên liệu phù hợp như yến chưng đường phèn, Yến chưng đông trùng hạ thảo
Cửa Cuốn Nhanh, Cửa Cuốn Tốc Độ Cao MECi – High Speed Doors
Cửa Cuốn Nhanh, Cửa Cuốn Tốc Độ Cao MECi – High Speed Doors Cửa Cuốn Nhanh – Cửa Cuốn Tốc Độ Cao là một sản phẩm thường được lắp đặt tại các khu vực cửa kho, cửa nhà máy, khu vực sản xuất, khu vực đông lạnh, khu nghiên cứu, phòng sạch... Với khả năng đóng mở nhanh chóng, cửa cuốn tốc độ cao hay còn gọi là cửa cuốn nhựa pvc giúp giảm thất thoát nhiệt, hạn chế bụi bẩn, côn trùng xâm nhập trong quá trình di chuyển hàng hóa giữa các khu vực. https://sites.google.com/view/cua-cuon-nhanh-pvc So với các sản phẩm cùng chức năng giữ nhiệt, ngăn bụi bẩn, ngăn côn trùng, thì cửa cuốn tốc độ cao còn có những ưu điểm đặc biệt sau: · Tốc độ đóng mở nhanh giúp hạn chế tối đa lưu thông không khí giữa 2 khu vực. · Tự động đóng mở nhờ cảm biến mắt thần phát hiện người và vật thể. Có thể điều chỉnh khoảng cách phát hiện vật thể của mắt thần. · Độ bền vật liệu cao, chi phí bảo trì thấp. Hợp kim nhôm tăng cường có độ bên cao, tấm nhựa pvc có thể được thay thế một cách dễ dàng khi hỏng hóc. · Cài đặt nhanh, dễ dàng, đảm bảo an toàn trong quá trình sử dụng nhờ cảm biến dừng khi có người hoặc vật thể đi qua. · Thay thế cho thao tác đóng mở cửa tiện lợi, tiết kiệm thời gian và nhân sự Tuy nhiên, Qúy khách có thể lắp đặt kết hợp giữa cửa cuốn nhanh và màn nhựa pvc cho nhà xưởng để ngăn côn trùng, bụi bẩn hiệu quả hơn. Sản xuất cửa cuốn nhanh nhựa pvc Công ty cổ phần Công nghiệp Meci Sài Gòn là đơn vị chuyên nhập khẩu linh kiện và sản xuất thi công cửa cuốn nhanh chất lượng đứng #1 trên thị trường Hồ Chí Minh Chúng tôi đã thi công hàng ngàn côn trình lớn cho các nhãn hàng lớn như Unilever, Olam, dược phẩm Nanogen, Nutrifood, Samsung... chúng tôi tự tin đáp ứng được tất cả những yêu cầu khắc khe của Qúy khách Xem công trình cửa cuốn nhanh lắp đặt tại công ty Dược phẩm Nanoge Lâm Đồng: https://manremnhua.net/cap-toc-thi-cong-cong-trinh-cho-cong-ty-duoc-pham-lam-dong-kip-tien-do Linh kiện cửa cuốn nhanh pvc Meci là đơn vị nhập trực tiếp cửa cuốn nhanh theo tiêu chuẩn Châu Âu, tất cả các linh kiện luôn sẵn có ở kho đảm bảo thi công nhanh chóng cho khách, không mất thời gian chờ đợi khi cần thay linh kiện. Một bộ cửa cuốn nhanh tiêu chuẩn Meci sẽ có đầy đủ các linh kiện và phụ kiện sau: https://manremnhua.net/linh-kien-cua-cuon-nhanh-meci Chính sách bảo hành cửa cuốn nhanh Meci Meci chuyên thi công lắp đặt cửa cuốn nhanh cho các nhà máy nhà xưởng, toàn bộ chúng tôi nhập trực tiếp. Có đầy đủ linh kiện để bảo hành, không mất nhiều thời gian chờ đợi. Sản phẩm được bảo hành theo điều kiện quy định của nhà sản xuất, không bảo hành đối với các vật tư tiêu hao Thời gian bảo hành Bảo hành thiết bị trong vòng 24 tháng kể từ ngày nghiệm thu sản phẩm Chính sách bảo hành ưu đãi cho khách hàng Meci Meci luôn chú trọng đến vấn đề bảo hành, bảo dưỡng cho khách hàng sau khi lắp đặt. Qúy khách sẽ nhận được dịch vụ bảo trì định kỳ MIỄN PHÍ 6 tháng / lần (trong thời gian bảo hành). Meci sẽ có hệ thống nhắc bảo trì tự động, tới thời hạn bảo trì sẽ có kỹ thuật liên hệ và xuống trực tiếp tại kho Qúy khách, không cần khách hàng phải liên hệ tới công ty. Xem thêm chi tiết chính sách bảo hành cửa cuốn nhanh Một số lỗi thường gặp và cách khắc phục Lỗi 1: Cài đặt hành trình cửa cuốn Là một loại cửa cuốn đóng mở nhanh sử dụng đa phần đều là động cơ hiện đại, khi khách hàng lắp đặt cửa cuốn pvc thì đội ngũ nhân viên của Meci sẽ cài đặt toàn bộ hành trình cửa cuốn. Việc cài đặt cực kì dễ dàng, không tốn nhiều thời gian và ngay cả bạn vẫn có thể cài đặt được Lỗi 2: Bộ công tắc hành trình cửa cuốn Cửa cuốn tốc độ cao bao gồm các thành phần sau: khung cửa cuốn nhanh; Động cơ – Motor AC Servo; Tủ điều khiển; Mắt thần Radar; Màn nhựa pvc; Khớp nối; Photocell (Cảm biến gương). Mỗi một bộ phận đều sẽ có nhiệm vụ khác nhau, chúng đều có mối liên hệ mật thiết với nhau. Do vậy khi một trong chúng bị lỗi sẽ dẫn đến cửa không hoạt động. Xem cách khắc phục chi tiết: https://mecidoors.com/loi-cua-cuon-nhanh-va-cach-khac-phuc https://youtu.be/UV78Ff-C-a8 https://www.pinterest.com/pin/898608931872793020 https://twitter.com/NhuapvcM/status/1529386198212681729
Quietum Plus- Simple Way To Support Your Hearing Health
Quietum Plus is the revolutionary dietary formula that is comprised of natural extracts to support healthy hearing. It shall improve the ear health by repairing and boosting your auditory nerves to stimulate healthy hearing process. The manufacturer has made the capsules with the proper combination of essential vitamins, plants, herbs and also included tips that can support the quality of healthy hearing. This is a simple and effective remedy that can create a healthy impact in lives of people who wish to regain their hearing ability What is Quietum Plus? Quietum Plus is an all-natural dietary supplement that aims to cure tinnitus and reverse its core symptoms. Overall, it is designed with exact and careful portions of potent herbal composites which are known to improve the functional efficiency of the human ear. And it does all by triggering the capacity of the neural circuits present in the central nervous system. More precisely, the supplement is designed to address the problem of tinnitus by stopping the debilitating noise in the ears and restoring clear hearing. Studies tell that tinnitus is a result of the improper activity of neurotransmitters and the poor functioning of brain cells. Therefore, we correlate this scientific report to the claims of Quietum Plus makers. As a matter of fact, the maker of this dietary supplement claims that Quietum Plus has a powerful and 100% risk free formula that targets the nerve functioning and performance of neurotransmitters to enhance hearing. In a nutshell, we can assume in the light of its company remarks that Quietum Plus is a power-packed supplement with an infinite amount of nutrients, vitamins, and minerals to enrich the brain and improve hearing as well as cognition performance. How does Quietum Plus work? As mentioned above, tinnitus is a hearing problem that occurs due to the poor performance of neurotransmitters and damaged cells of the brain. With that scientific identification, this supplement is created to target this underlying cause of tinnitus. As it combines the nutrients and power of all potent and essential ingredients to bring utmost promising results. Essentially, Quietum Plus Supplement has the exact portion of the carefully-picked ingredients that synergically work to bring holistic results. Moreover, it has some particular nutrients that help the formula to quickly absorb into the central nervous system and start repairing the damaged or weak cells. It starts with nourishing the brain cells that implicitly support the functioning of the auditory system. To be more precise, QuietumPlus works in four stages or we can say there are four phases involved in its working strategy. Stage 1 In the first stage, the supplement starts the absorption process and provides enough nourishment to the brain cells. As soon as brain cells get nourishments, the whole course of the itinerary begins. With the nourishment of damaged cells, Quietum Plus begins to provide an inflammatory response to the brain and ear cells. This inflammatory process is crucial to clear the microbes and pathogens present in the affected area. Stage 2 Once the extermination process of microbes ends, the repairing or actual healing process begins. The second stage is very important as it involves hearing improvement. During this stage, the brain cells that get nourishment in this first stage come to action and start targeting all the factors that may lead to debilitating noise in the ears or any other malfunctioning of the auditory system. In addition to that, the creator of this anti-tinnitus supplement claims that it also repairs the inter-connections of brain cells. The fortification of these connections strengthens the transmission of brain signals to the auditory system. That’s how this dietary supplement stops ringing and buzzing in their ears and resumes optimal hearing. Stage 3 The third stage helps to integrate the development of cognitive functions along with fortifying brain performance. It is noteworthy that stage three provides complete support to brain health and improves cognitive abilities. Stage 4 The last stage comes once the supplement fixes all problems occurring in the central nervous system. The fourth or last stage fully targets on fortifying the auditory cells. During this stage, this nutritional supplement ensures to resume clear and optimal hearing by providing peculiar support to the auditory system and enhancing hearing capacities. Buy Quietum Plus https://quietumplus-usa.com/hearing-aids
Leptofix- A Powerful Weight Loss Supplement
Leptofix is a proven weight loss supplement that is advertised to treat the root cause of obesity with its 100% all-natural and healthy formula. Its formula uses only pure and premium quality ingredients that are added in exact portions to make an incredible formula and gain the maximum potency. Due to that, the formula is marketed as a miraculous weight loss remedy. What is Leptofix? LeptoFix Supplement is an all-natural dietary supplement that aims to trigger the natural fat-burning mechanism of the body. Precisely, it uses a pure combination of about twenty-two ingredients that work in synergy to fix the underlying cause of excessive weight gain. By targeting the real root cause, the formula aims to jumpstart an effortless weight loss journey. The creators claim that by taking the daily dose of this advanced supplement, you do not need to put in any extra effort such as following starving diet plans, doing heavy exercises, etc. Instead, the formula of this breakthrough supplement is designed to remove all the raw fat from all parts of your body e.g, from your face, arms, thighs, hips, and of course belly. Apart from working as a fat-burning restarter, the LeptoFix formula also offers plenty of benefits to other crucial systems of the body, such as the cardiovascular system. Moreover, it supports bone and joint health, turbo-boosts the metabolism of the body, and supports healthy arteries. How does Leptofix work? LeptoFix has been formulated to improve leptin signaling processes. Leptin is a type of hormone that is typically released from fat cells housed within our adipose tissues. Its role is to send signals to a part of the brain called the hypothalamus. In particular, these signals inform the brain of satiety, which can help regulate food intake and energy outflow. Above all, it serves as an indicator to consumers that they are full, and no more food is needed (at least for a certain period). The main problem that arises with the leptin hormone is that it can fluctuate. Based on clinical studies, obese people are more likely to have higher leptin levels in the body than under or normal-weight people. This can stimulate leptin sensitivity, a condition where the brain no longer receives essential signals to make informative decisions. If the brain's message of fullness is not received, then fat cells will continue to produce leptin. Sadly, consumers are left with hunger cries that end up being fueled unceasingly. Ultimately, it is a matter of fixing one particular mishap in communication, which is what LeptoFix is deemed responsible for. How might regulating leptin signaling processes affect other aspects of health? Take obesity, for instance; an increase in leptin causes it, and this condition has been linked to high blood pressure, high LDL and triglycerides levels, overeating, increased risk of heart diseases, and many others. Buy Leptofix https://lepto-fix.com/weight-loss
Thuốc chống động kinh Pregabalin là gì? Những điều bạn cần biết
Pregabalin được tổng hợp vào năm 1990 bởi nhà hóa dược học Richard Bruce Silverman tại Đại học Northwestern ở Evanston, Illinois. Theo đó, trong thời gian từ 1988 đến 1990, Ryszard Andruszkiewicz – một thành viên trong nhóm nghiên cứu đã đến thăm và tổng hợp một loạt các phân tử cho Silverman. Trong đó có một phân tử tỏ ra đặc biệt hứa hẹn. Phân tử này được định hình hiệu quả để có khả năng vận chuyển vào não, nơi nó kích hoạt một loại enzym là axit L-glutamic decarboxylase. Silverman hy vọng rằng enzym này sẽ làm tăng sản xuất chất dẫn truyền thần kinh ức chế GABA và có tác dụng ngăn chặn các cơn co giật. Sau đó, các phân tử được gửi đến Công ty Dược phẩm Parke – Davis để được thử nghiệm và nhận được sự chấp thuận tại Liên minh Châu Âu vào năm 2004. Vào tháng 12 năm 2004, pregabalin được FDA chấp thuận để điều trị động kinh, đau thần kinh do tiểu đường và đau dây thần kinh hậu phẫu thuật. Sau đó, pregabalin xuất hiện trên thị trường Hoa Kỳ với tên thương mại là Lyrica vào mùa thu năm 2005. Vào năm 2017, FDA đã phê duyệt Lyrica CR (dạng giải phóng kéo dài của pregabalin). Tuy nhiên, khác với công thức giải phóng ngay lập tức, Lyrica CR không được chấp thuận để điều trị chứng đau cơ xơ hóa hoặc bổ sung vào liệu pháp điều trị cho người lớn bị động kinh khởi phát một phần. Dược lý và cơ chế hoạt động Mặc dù cơ chế hoạt động vẫn chưa được làm sáng tỏ đầy đủ, nhưng kết quả từ các nghiên cứu trên động vật cho thấy, sự gắn kết ở trước synap của pregabalin với các kênh canxi phụ thuộc điện thế là chìa khóa cho các tác dụng chống co giật và chống ung thư. Theo đó, pregabalin liên kết với tiểu đơn vị 𝛂2 – 𝞭 trên các kênh canxi phụ thuộc điện thế, từ đó điều chỉnh việc giải phóng một số chất dẫn truyền thần kinh kích thích bao gồm glutamate, norepinephrine, chất-P và peptide liên quan đến gen calcitonin. Ngoài ra, pregabalin cũng ngăn không cho tiểu đơn vị 𝛂2 – 𝞭 được vận chuyển từ hạch gốc lưng đến sừng lưng cột sống. Cơ chế này được cho là góp phần vào tác dụng của thuốc. Mặt khác, pregabalin có cấu trúc tương tự chất ức chế thần kinh trung ương GABA, nhưng lại không gắn trực tiếp với các thụ thể như GABAA, GABAB, hoặc thụ thể của benzodiazepin. Tuy nhiên, trong thử nghiệm trên các tế bào thần kinh nuôi cấy, việc sử dụng pregabalin lâu dài sẽ làm tăng mật độ các protein vận chuyển cũng như tăng tốc độ vận chuyển GABA. Đọc thêm tại https://nhathuocngocanh.com/hoat-chat/pregabalin/
Robotic Endoscopy And Its Impact On Advance Surgical Procedures Development
Usually, robot-assisted surgical endoscopy is feasible by technical means. This robot-assisted surgical endoscopy appears to simplify the most complex procedures by improving the overall exposure, visualization, and tissue manipulation processes. It has the entire potential to reduce the learning curve and broaden the overall adoption of the challenging procedures involving suturing, tissue dissection, and other crucial techniques. Also, the Robotic-assisted colonoscopy is well intended to improvise the patient’s exam tolerance, reduce pain, reduce the risk of perforation and promote the cecal intubation regardless of the endoscopist's capability. In addition, for all those where it is necessary for the colonoscope to have the active motion and to mould to the colon. With the help of robotic assistance, the physician could easily manipulate the colonoscope within a specific distance. In accordance with the UK’s NED (National Endoscopy Database), an average of about 35,478 endoscopy procedures were conducted per week by around 3007 endoscopists, which signifies 12 procedures per endoscopist. The overall process of Endoscopy began as a gastrointestinal (GI) diagnosis method, and it has become a significant treatment method for GI pathologies in recent times. The device or the equipment has been in constant evolution since the implementation of the electric lamp, the coming of the flexible endoscopes, the recent development of robotic methods and the incorporation of ultrasonography. Endoscopic devices or the instruments had already been utilized for the bladder, urethra, and uterine cervix. However, in 1868, it was Adolf Kussmaul who had performed the 1st direct esophagogastroscopy. After attending a sword-swallower performance, he had demonstrated that it was possible to launch a rigid tube to the stomach if the neck and head hyperextended, though without any sufficient illumination. Joseph Leiter, in the year 1882, had included an electrical lamp on the extreme tip of the endoscope. In 2020, the overall valuation of the Global Robotic Endoscopy Devices Market was around USD 1.40 billion. It is anticipated to reach around USD 5.49 billion by 2030, representing an overall CAGR of 14.65 percent throughout the forecasted period. Recent Developments in the Robotic Endoscopy Devices Market In the month of June 2021, Johnson & Johnson (US) launched the ENSEAL X1 Curved Jaw Tissue Sealer. This advanced bipolar energy device increments the procedural efficiency and offers more robust sealing & access to various body tissues. It is an intuitive and intelligent device that offers more secure sealing and ease of use that improvises the currently available advanced bipolar sealing devices. Olympus Corporation (Japan) had paid an overall sum of USD 300 million in the month of May 2021 for Medi-Tate Ltd. (Israel), which had offered Olympus in-office therapy for benign prostatic hyperplasia (BPH) to extend its business line in-office treatment for the treatment of benign prostatic hyperplasia and to solidify its entire position as a leader in the domain of urological devices. Endoscopy, which is widely known in recent times, is mainly because of the invention of the flexible endoscope by Schindler and Wolf in the year 1932, spreading the overall usage of diagnostic endoscopy. Moreover, the emergence of technology like video-endoscopy has extended its utilization in the entire treatment of GI pathologies. Moreover, with the propagation and evolution of endoscopy, two major dilemmas have emerged in recent times. Both the willingness to conduct NOTES (Natural Orifice Transluminal Endoscopic Surgeries) and the ESD (endoscopic submucosal dissection), resecting the lesions each time complex and wider, bring the requirement of the platforms that promote forceps manipulation and stability that the conventional equipment does not. Also, in adding up to that, there is the ultimate pursuit of automation for the equipment to do what, nowadays, only the endoscopist physician is competent.
SynoGut - Advanced Digestive Formula
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