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Liver Transplant: A Hope For A Better Future

The liver is the human body’s most important gland. It helps break down protein from food to make it easier for the body to absorb. It is an essential organ, and the body cannot survive without it. In addition, it aids in the digestion and growth of the body.

It is located below the diaphragm on the right-hand side of the abdomen. It also assists with many more metabolism-related activities of the body and is vital for our survival.

A liver transplant is a long and complicated process, and it is always recommended to go to the top liver transplant hospital in India for the procedure.

What Leads To Liver Transplant?

The main reasons that lead to anyone needing a liver transplant are -

1. Liver Failure

A patient will require a liver transplant in the case of a liver failure. This can happen for various reasons, and in case of a complete liver failure, a patient will need a liver donor and have to go through the transplant procedure.

2. Liver Cirrhosis

Liver cirrhosis is a condition where the liver has scarring. It is a degenerative disease, and doctors at the top liver transplant hospital in India will recommend a transplant before it’s too late.

Alcohol consumption worsens the disease, and many patients affected by this condition are frequent drinkers. In addition, consuming alcohol once diagnosed accelerates the symptoms and must be avoided at all costs.

3. Doctors Recommendation

Doctors may recommend a transplant if they spot any signs of an unhealthy organ. If a patients liver shows signs of impending failure or deterioration, they may recommend the procedure to get ahead of the problem. This only happens in rare cases and has no particular cause, and is usually the case if the patient has a pre-existing liver condition.

How Does The Procedure Work?

In the case of a liver transplant, the patient’s liver is removed from the body and replaced with a healthy liver from a donor’s body. It is quite an ordeal, and the procedure can take 6-12 hours of operation.

Therefore, to be on the safe side, the patient should consider the top liver transplant hospital in India and consult experienced professionals before proceeding with the procedure.

The procedure does take a toll on the patient physically and mentally, and full recovery can take several months. The duration that a patient has to stay in the hospital is also long and takes weeks before the procedure. This is because the operation is of the open type and is quite complex.

However, one has no reason to dismiss a transplant if it is done at a reputed hospital and performed by top doctors with experience.

Conclusion

It is impossible to live with an unhealthy organ, even more so when it is a vital organ like the liver. A patient that gets a liver transplant essentially gets another chance at life. With a healthy liver, the patient can live on for many more years and perform all the daily activities as they used to.

Therefore, a liver transplant does become a hope for a better future for many patients worldwide.
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How COVID-19 Impacted on Electromyography Devices ?
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IMPACT ON PRICE Because of COVID-19, the market is upset to a major level. The few foundations have been stay shut while others had downsized the activities or put a pause to the extension plans as they attempted to endure the uncommon emergency. States must develop and implement policies that allow for interstate licensure and practice of medicine (entailing the use of telemedicine) to enable consultation and communication to remote areas and ensure the swift flow of information across state lines. Now, as the demand for telehealth innovation is turning out to be very demanding by human beings, this will make the market more competitive due to new and more innovative equipment that will be launched by the makers, by decreasing the overall cost of the new and innovative new product launches. The current COVID-19 episode has influenced essentially every industry on earth, and the electromyography devices market is no exemption. 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A large pool of the population is affected by the COVID-19 virus, and its spread is expanding across the world in the last few months. To deal with the COVID-19 outbreak challenges, many electromyography devices market players are creating new strategies. To tackle the pandemic situation and to increase the company revenue and growth, companies are now opting for digital media such as telecommunication, mobile applications, webinars, and other digital media to support patient requirements. Moreover, to accomplish the market demand, small as well as major market players utilizing the strategy such as partnerships, agreements, and organizing conferences. It is predicted that these strategies are anticipated to escalate up the company revenue and its growth in the forecasted period. For instance, · In April 2020, Neurosoft S.A. organized NYC Neuromodulation 2020 Conference. This conference has anticipated enhancing the company’s presence in the global market. 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Also, due to the Coronavirus disease (COVID-19) pandemic outbreak, manufacturers are forced to find new contract manufacturers and suppliers for more manufacturing activities to different or unique facilities location that are less impacted by the outbreak. The impact of Covid-19 has created huge price impact on the government as well as on patient families that they have to buy the drugs on higher rate as compared to the average rate. IMPACT ON DEMAND The Coronavirus zone is the result of various markets around the world. This is the cause of the widespread closures and isolation that are affecting world economic activity. As the cases increases in the month of April 2020, the sudden surge in demand has seen, and drugs and medical devices went out of stock. Moreover, the decrease in the revenue of the key market players depicted in their quarterly results, such as Medtronic, among others, gave the evidence of decline in the demand for medical devices due to the emergence of the COVID-19 pandemic. For instance, · Medtronic reported a decline of 1% in its brain therapies net sales of the financial results of 2020 as compared to 2019. The reduction was primarily motivated by the detrimental effects of the COVID-19 pandemic and the subsequent deferral to companies of medical procedures. · Impact on rare disease organization also faced significant fundraising income loss, this consequential income loss may leads to loss of various people jobs associated with the organizations. The cutting or income loss leads to the reducing staff, canceling offices leases, and delay or cutting office programs. The impact of covid-19 majorly impacted the organizations if the revenues loss projections do not change, this will leads to temporarily or permanently shut down of small and middle foundations and organizations. IMPACT ON SUPPLY As the epidemic intensifies, supply chains can be at significant risk due to over-located locations that can potentially be disrupted. The supply chain of drugs, devices, and services has been disrupted. The spread of COVID-19 makes it difficult for governments to use these drugs; the availability of these systems faces constant challenges due to their components of use and limited initial needs. Moreover, as there is no cure for the disease, only physical activities/therapies may suppress the symptoms also affected by pandemics. According to the NORD (National Organization for Rare Disorders), in the U.S. stated that 74% of the population have had canceled medical appointments due to Covid-19 pandemic, 69% of population concerned about their medication and medical supplies. For instance, • In June, ResMed stated that, due to the Covid-19 pandemic company sleep apnea business segment adversely affected including sleep clinics, physician practices, HME suppliers. As new patients are prescribed sleep apnea devices such as PAP, CPAP devices for the treatment through hospitals that are directing their resources to critical care, including COVID-19 treatment. The covid 19 impacts may continue to decrease demand for the sleep apnea devices sale STRATEGIC DECISIONS OF GOVERNMENT AND MANUFACTURERS As such, market participants are involved in the production of drugs, expanding their business through a variety of programs, including collaboration, contracts, and pipeline development, collaboration, and market expansion. It is expected that the strategic decisions of these companies will provide significant opportunities for market participants operating in the Niemann-Pick Disease market. For instance, · In July 2020, Abbott announced that it had received FDA approval for the use of the Patient Controller App on compatible personal Apple smartphone devices. The approval will allow the patient living with neurological conditions to manage their therapy directly from personal smartphone. · In May 2020, Philips, a global leader in health technology, joined forces with the American Telemedicine Association (ATA) to help further the adoption of telehealth across the industry, demonstrating its commitment to connecting care across acute, post-acute, and home care settings. The continued collaboration spotlights telehealth's growing adoption and momentum amidst COVID-19 and the need to convey the exponential shift to telehealth capabilities. · In U.S., NIH supports the research survey of “CURE EPILEPSY ORGANIZATION” to examine the impact of Covid-19 on Rare Disease Community. The survey includes more than 200 rare diseases including the brain, immune system disorders, heart, lungs, brain development diseases, and more. CONCLUSION As this pandemic situation has resulted in many restrictions in different places around the world, still the market players of dealing in rare diseases therapy and services were able to manage their service stock. Different companies dealing in metabolic diseases therapy services were finding out their own way to deal with this pandemic situation. The government and companies around the globe are working together and have issued advice for those undergoing therapies centers during these unprecedented times during COVID 19 lockdown around the world. The supply chain was destroyed, but several steps were taken by the government and companies, which will help them, get their needed output for therapy service. By increasing the material price, the companies can maintain their overall revenue. Thus, different foundations, organizations,, and services center markets are finding ways to deal with this pandemic situation. Figure 1: Relationship between Coronavirus and Lysosome storage diseases : Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway
How COVID-19 Impacted on Nutraceutical Packaging in Healthcare Industry ?
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The government initiatives to support industries in order to manufacture innovative packaging products will boost the growth of the market. For example, · European Union (EU)- funded project NanoPack aims to develop packaging solutions that increase product life after packaging by using novel anti-microbial surface application on the food packaging product surface. The Nanopack antibacterial film extends the shelf life of the product by two days. This two day increase in shelf life increase product stability by 40%. Therefore, such initiatives taken up by the governments which aim to help the manufacturers to manufacture safe products for the nutraceutical packaging will propel the growth of the market. STRATEGIC DECISIONS OF MANUFACTURERS AFTER COVID-19 TO GAIN COMPETITIVE MARKET SHARE To deal with the COVID-19 outbreak challenges many nutraceutical packaging market players are creating new strategies. It is predicted that these strategies are providing high chances to escalate up company revenue and its growth in the forecast period. Similarly, growing opportunities in innovative packaging solutions is attracting a larger consumer base for the nutraceutical packaged products. Increase in the demand for the nutraceuticals has made companies to launch the new products in spite of the COVID- 19 challenges and to gain a larger market share. Despite of the COVID – 19 pandemic outbreak, the manufacturers have been creating new opportunities by themselves by participating in exhibitions in order to spread the awareness about the nutraceuticals and their nutritional benefits which helps in boosting the immunity of the consumers. For instance, · In 2021, MJS packaging announced that they will exhibit for the first time since the start of COVID- 19 pandemic at the 2021 Cannabusiness international market place Michigan summit and expo in Michigan. Therefore, such product launches, exhibition of the products at the expos and vents in order to increase their consumer base are the strategic decisions which are taken up the market players to gain larger market share. PRICE IMPACT The COVID-19 had a terrible impact on the global economy. Many establishments have to remain shut while others scale down their operations or put on hold expansion plans as they survive the unprecedented crisis. The other impact of the COVID-19 pandemic outbreak is the delay or fluctuation of raw material supply for nutraceutical packaging manufacturing. This fluctuation has resulted in increase in price of raw material, which has impacted the prices of nutraceutical packaging products. IMPACT ON DEMAND There is a rapid increase in demand for the nutraceuticals increasing popularity for the nutraceutical packaging as well. Demand for the increased shelf life of food products across the globe is expected to increase the growth of the market in the COVID-19 period as well. There is an increasing consciousness about health and weight management is playing a crucial role in the demand for the global nutraceutical packaging market. On an average, the consumers have increased have increased their monthly spending on vitamins, minerals and supplements products by 10-15% since the COVID- 19 began. The increase in the awareness among the consumers about the consumption of the nutraceuticals is that they can build the immunity that is highly required in the COVID- 19 pandemic period has positively affected on the nutraceutical packaging as well. With the rise in the consumption of the nutraceutical in order to maintain the good health and fitness, the demand for the nutraceutical packaging also increased. Therefore, there has been a constant increase in the demand for the nutraceuticals which positively affected on the nutraceuticals packaging market as the packaging of the vitamins, minerals and other dietary supplements is the major factor that attracted the attention of the consumers. IMPACT ON SUPPLY CHAIN During the pandemic situation, the supply chain was majorly disrupted due to a lack of resources and transportation. Also, the governments across the world have implemented various restrictions and lockdowns to prevent the spread of the disease. In the same way, many governments have restricted the movement of goods across the countries and the entire supply chain was distorted. Owing to the disrupted supply chain, the transportation of raw materials has been interrupted and the production of nutraceutical packaging products was halted. Similarly, the manufacturers aren’t able to visit the customers such as nutraceutical companies to provide them with the packaging materials due to the implementation of lockdowns across the various parts of the world. Thus the demand for nutraceutical products has been tremendously increasing whereas the packaging materials production has been disrupted. As a result, the COVID- 19 pandemic has negatively impacted on the supply chain of the nutraceuticals packaging market. CONCLUSION COVID- 19 pandemic has taken a toll on the population and economy. A collaborative effort on governments, public health departments and hospital fraternity to fight corona virus has led to the economic slowdowns, lockdowns and extreme public safety measures. Due to the increasing health conscious ness among the consumers, the demand for the nutraceuticals has been increasing constantly in the COVID – 19 pandemic periods. This is mainly because of precautionary measures which are followed by the consumers for the COVID-19 which in involves the intake of nutraceuticals. However, the supply chain has disrupted during the outbreak scenario because the demand is more for these products. As unlocking of the lockdown being started in various regions of the world, it is expected that the supply chain became normalized for the market.
What Are the Benefits of Using Lavender Oil on Your Hair?
Essential oils are becoming more popular as home remedies. Among these, lavender has become a popular essential oil. Lavender essential oils are extracted directly from the lavender plant and have a heavenly scent. The end result of using special distillation techniques is a highly concentrated extract of lavender's useful compounds, full of health benefits and more. These include benefits such as pain relief, migraine relief, air freshening, cleaning, and even hair care. According to research, it has numerous benefits for hair and healthy, beautiful locks. How does lavender oil benefits hair health? Lavender oil has a variety of beneficial properties that may help with hair health, some of which are listed below. 1. It promotes hair growth. The lavender essential oil has recently gained popularity for its ability to promote hair growth. According to a 2016 study According to a reliable source, applying lavender oil to mice caused them to grow more hair. Their hair grew thicker and faster than usual as well. This benefit is far more effective when the oil can penetrate the skin. According to these studies, lavender oil may aid in the treatment of conditions such as pattern baldness or alopecia. Human studies are needed to prove this, though people can safely try the oil in their hair. 2. It has antimicrobial properties According to this 2014 review, lavender also has antimicrobial properties. This means it aids in the prevention of the growth of bacteria and fungi. When applied to the hair or scalp, this may help to prevent common hair and scalp problems. It may help to prevent itchy scalp, dandruff, and even infections. 3. It may aid in the prevention or eradication of head lice According to a 2011 study, the lavender essential oil can help prevent head lice. It may even be effective against head lice. The lavender essential oil was tested alongside another essential oil, tea tree oil, in the study. Though more research is needed, using lavender oil may reduce the risk of getting lice. It could be even more effective if you combine it with tea tree oil. However, these oils should not be used in place of your prescribed treatment plan; you should not rely solely on oils to treat head lice. 4. It may help to reduce skin inflammation Lavender is sometimes used as a natural treatment for skin inflammation and burns. Its essential oil form may be beneficial for scalp inflammation and dryness. Lavender oil was successfully used topically on skin inflammations and ulcers in a 2012 study. It reduced inflammation and sped up the healing process. 5. It has a calming effect as well as a divine fragrance Lavender has a wonderful smell as an added bonus. Its aroma has the ability to literally calm your nervous system. In this 2012 study, human subjects reported feeling more relaxed, pleasurable, and in better moods after inhaling the fragrance. Is there anything bad about lavender oil? Make sure not to use too much oil on your scalp or on your products. Excessive use of essential oils can irritate the skin. To avoid this, always combine plain oils with a carrier oil. If you develop a rash, hives, or dermatitis despite using carrier oils, discontinue use immediately. It could be an indication that you are allergic to lavender. A lot of people are. Never consume undiluted essential oils or get them in your eyes. If you get them in your eyes, immediately flush them out with cool water. If this Blog Finds Helpful. Must Share and Comment Your Views., Thank you!! Also Read: Lavender oil lavender oil for skin Also Read About: Rosemary essential oil Visit: how to use rosemary oil for hair growth how to use rosemary essential oil for face
What Causes Strawberry Legs And How To Get Rid Of It?
Summer is arrived, which means you're most likely showing a little more skin. As our gams finally receive their due, pants become shorts, maxi dresses become minis, and skirts become minis. Short hemlines, on the other hand, may be undesirable to those whose legs are spotted, bumpy, or spotty. Let's learn more about how a dermatologist treats and prevents skin diseases known as "strawberry legs." What Are 'Strawberry Legs,' Exactly? Strawberry legs refers to a dotty appearance of the legs, mainly around the hair follicles. The dots depict the buildup of common skin elements in and around the hair and oil glands. Keratin is a type of protein that is found in (the main protein in the skin) * Melanin is a pigment found in the skin (the source of pigment) * Sebum is a type of oil that is produced by (natural oil of the skin) * Bacteria are microorganisms (often, normal skin flora) The name "strawberry legs" refers to the dark pores and dots or red pimples that emerge on the lower thighs and resemble strawberry seeds. Strawberry legs are not hazardous in terms of health, but they are ugly. Strawberry Legs: What Causes Them and How to Treat Them While the appearance of strawberry legs is typically the same no matter what caused it, there are a number of causes. Knowing what's causing your dotted gams can allow you to address the appropriate ailment. The four most prevalent causes of strawberry legs, as well as how to cure them, are listed below. 1. Clogged Pores Clogged pores on your legs are just as common as clogged pores on your face. Because of heredity and thicker body hair, some people have larger pores, and while the pores themselves aren't inherently irritating, they can become problematic when they become blocked with germs, dead skin, and sebum. When clogged pores on the legs are exposed to air, the debris dries up and darkens, in the same way that a blackhead on the face does. Treat with: Chemical and physical exfoliation. Exfoliation, which is part of your facial skincare routine, can be used to cure congested pores on the legs or anyplace else on the body. My personal favourite for my patients is chemical exfoliation, which uses chemicals such as acids and retinols to stimulate skin cell turnover and clear pores. This eliminates keratin, oils, and other skin detritus gently, opening up pores and follicles and preventing secondary bacterial buildup. Acne and folliculitis bacteria grow in oil-clogged hair follicles, so eliminating that build-up is critical. Look for a body wash or moisturiser that contains alpha-hydroxy acids (AHAs) and beta-hydroxy acids (BHAs), notably glycolic acid and salicylic acid, to exfoliate dead skin cells and other debris that create clogged pores. These acids gently exfoliate the skin by minimising the'stickiness' of dead or dying skin cells. This helps to open up the pores while also giving the skin a great textural shift and radiance. 2. Folliculitis Folliculitis is a skin disorder that causes inflamed or infected hair follicles. The most common sign is little red pimples around the hair follicles. Hair loss or scarring in the affected area may occur in extreme situations. The majority of instances, however, are small and normally resolve within a few days. It's crucial to note that folliculitis is a catch-all term for inflammation of the hair follicle. This can be contagious due to microorganisms like staphylococcus or sterile due to oil buildup or shaving stress. Treat with: Antibiotics, both oral and topical. Folliculitis is a "tricky condition" to treat, which is why you should consult a dermatologist before trying any at-home therapies. Folliculitis can be sterile, with red, pus-filled pimples forming as a result of causes like clogged pores and shaving. They can, however, indicate a superficial skin infection caused by bacteria or yeast such as staph and pityrosporum. While the former can be treated with over-the-counter medications, the latter may require prescriptions for antibiotic creams or even pills to resolve. A simple swab can be used by a dermatologist to assess whether or not organisms should be targeted. If there are, it might save you a lot of time and effort in developing successful at-home habits. Treat with: Antibacterial skincare. At-home treatments range from lifestyle changes to skincare. To begin, change out of your sweaty training clothes and shower as quickly as possible. In the shower, lather up with antibacterial soap. Treat with: Laser hair removal treatment. You should also reconsider your shaving routine. Use a soothing shave cream in addition to converting from a multi-bladed razor to a disposable razor. In return for less rough skin, the closest shave is compromised. The risk of folliculitis is inversely associated to a close shave. He also suggests shaving with the grain rather than against it every two to three shaves. If you're prone to razor bumps, laser hair removal with a dermatologist will save you a lot of time and aggravation in the long run. 3. Keratosis Pilaris Keratosis pilaris (KP), popularly known as "chicken skin," is a skin disorder characterised by the appearance of small bumps on the skin. Keratosis pilaris most usually affects the upper outer arms, however it can also affect the thighs. Keratin accumulation in the hair follicles causes this. Treat with: Chemical exfoliation. Chemical exfoliants, like clogged pores, are frequently efficient in the treatment of keratosis pilaris, but prescription-strength treatments may also be beneficial. Exfoliative acids are my first line of defence against keratosis pilaris. If those don't work, a prescription-grade retinoid may be an option, but only after consulting with a dermatologist. While keratosis pilaris is usually a year-round condition, flare-ups are more likely in the winter when the skin is drier. Additionally, swimmers may aggravate the illness due to the dehydrating effects of chlorine and other pool chemicals. 4. Dry Skin Dry skin, as previously indicated, contributes to a number of skin diseases, including strawberry legs. Dehydrated skin is more susceptible to irritation, especially during shaving. Dry skin on the lower legs is more prone to razor burn, keratosis pilaris, folliculitis, and plugged pores, all of which can result in a spotty appearance. Treat with: Creams and moisturisers. For severely dry skin, a daily moisturising body lotion containing ammonium lactate is an excellent place to start, especially if it is scaly. Ichthyosis, or dry, scaly, or thickened skin, may not usually respond to regular creams and moisturisers, thus a dual-purpose formulation may be necessary. Because there is a thicker layer of dead skin on the surface, moisturising alone isn't always adequate. Exfoliating lotions gradually remove that layer, allowing richer moisturisers to penetrate deeper into the healthier layers beneath. In conclusion Strawberry legs are a catch-all name for a range of skin disorders, but there are a few things you can do at home and at the workplace to cure and prevent a bumpy or spotty appearance. Consult a board-certified dermatologist before attempting to treat yourself to ensure you understand the underlying cause of your illness.
How Impacted COVID-19 on Minimally Invasive Gastrointestinal Surgical Systems in Healthcare Industry ?
Impact of COVID-19 on Minimally Invasive Gastrointestinal Surgical Systems in Healthcare Industry OVERVIEW A recent SARS-CoV-2, virus has caused a general pandemic of respiratory disease, called COVID-19. The infection initially showed up in Wuhan, a city in China in December 2019. The patients experiencing COVID-19 are dealt with cautiously with all the safety measures since this sickness spreads quicker through actual contact. There are now numerous vaccines in use. The first mass vaccination program commenced in early December 2020 and as of 15 February 2021, 175.3 million vaccine doses have been administered. World Health Organization (WHO) issued an Emergency Use Listing (EULs) for the Pfizer COVID-19 vaccine (BNT162b2) on 31 December 2020, issued another two EULs for two versions of the AstraZeneca/Oxford COVID-19 vaccine, manufactured by the Serum Institute of India and SKBio on 15 February 2021. On 12 March 2021, WHO issued a EUL for the COVID-19 vaccine Ad26.COV2.S, developed by Janssen (Johnson & Johnson). · As per the WHO report, globally, as of 16 May 2021, there have been 162,177,376 confirmed cases of COVID-19, including 3,364,178 deaths, reported to WHO. As of 11 May 2021, a total of 1,264,164,553 vaccine doses have been administered. · As per the WHO report, In the United States of America, from 3 January 2020 to 16 May 2021, there have been 32,574,504 confirmed cases of COVID-19 with 579,664 deaths, reported to WHO. As of 6 May 2021, a total of 256,126,513 vaccine doses have been administered. · As per the European Centre for Disease Prevention and Control as of week 2021-13, 27 513 674 COVID-19 active cases and, 627 242 deaths have been reported in the EU/EEA. Even though immunization is found for COVID-19, safeguards incorporate incessant hand-wash, wearing a face veil, and keeping up social separating. IMPACT ON DEMAND Since the pandemic, due to the lockdown situation, the economic growth of a country is declining day by day. And the manufacturing units for various items shut down due to the non-availability of manpower. There will be opportunities in the coming time for manufacturers of digital health technologies to position themselves for the COVID-19 recovery. When COVID-19 responses ease, there will be an excess of elective surgery procedures in emergency clinics. The pre-appointment programs can help smooth out the planning, arrangement, and conveyance of the surgeons and the doctors. Cloud-based stages have an extraordinary preferred position in permitting the clinician and their representatives to design cases distantly while travel and medical clinic access limitations are set up. With the careful plans and embeds chose early, embed providers and emergency clinics have the chance to enhance their stock and creation (on account of patient-explicit custom parts) to effectively address the accumulation of cases once the circumstance permits. IMPACT ON SUPPLY Because of the pertinacious COVID-19 lockdown, sanctions have been forced by administrations of different nations. These limitations and boundaries across the nation’s borders prompted a diminishing stockpile because of restricted materials and labor force and the halting of the assembly line. Additionally, the manufacturers are also taking crucial steps to ensure the availability of raw materials by and also they have to look into the quality of products. But since the demand is increasing day by day, so as to meet the demand the major manufacturing and suppliers are collaborating with each other’s to ensure the supply of raw materials. AFTERMATH OF COVID-19 AND GOVERNMENT ROLE Minimally invasive techniques have revolutionized operative surgery. Computer-aided surgery and robotic surgical systems aim to ameliorate further on currently accessible minimally invasive surgery and open new horizons. In gastrointestinal surgery, robotic surgery is applied to a wide range of procedures but is still in its infancy. Most studies reported that robotic gastrointestinal surgery is workable and safe, provides improved dexterity, better visualization, reduced fatigue, and high levels of precision when compared to conventional laparoscopic surgery. In light of the fiery impacts of the infection, there are hypothetical dangers that the viral contamination could delay the wound healing of the patients as there have been limited visits to the hospitals due to the lockdown imposed by the government in different countries. STRATEGIC DECISIONS OF GOVERNMENT AND MANUFACTURERS The key players engaged in global wound healing manufacturing are making improvements to keep the speed during COVID-19. They are taking every single choice cautiously so the development can be expanded on a consistent schedule for the market. The manufacturers are likewise giving a great deal of consideration in the improvement of inventive items that can be utilized for the attractive impacts. Organizations working in the minimally invasive gastrointestinal surgical systems market are embracing a few systems, including joint effort, arrangements, association, and market development to improve their business. These essential choices by the organizations are required to give huge occasions to the market players working in the minimally invasive gastrointestinal surgical systems market. For instance, · In December 2020, Johnson & Johnson Services Inc, participated in the 39th annual J.P. Morgan Healthcare Conference. This helped the company to give the correct knowledge about their product and would help the company to further grow in the coming years. IMPACT ON PRICE Because of COVID-19, the market is upset to a major level, the few foundations need to stay shut while others downsize the activities or put on pause extension plans as they attempted to endure the uncommon emergency. The current COVID-19 episode has influenced essentially every industry on earth, and the minimally invasive gastrointestinal surgical systems market is no exemption. There has been a tremendous and sudden lessening in the volume of elective joint substitutions worldwide as wellbeing situation legitimately organize their COVID-19 reaction. Now, as the demand for telehealth innovation is turning out to be very demanding by a human being, and this will make the market more competitive due to new and more innovative equipment that will be launched by the makers, by decreasing the overall cost of the new and innovative minimally invasive gastrointestinal surgical systems and solutions. CONCLUSION There are no data on the safety, immunogenicity, or effectiveness regarding the treatment of inpatients with wound infections along with mild COVID-19 symptoms. The supply chain units are taking stringent measures and risk mitigation protocols to provide the devices to the manufacturers to the customer. The presence of key market players for the development and launch of the MIS gastrointestinal systems will increase the net sales and may show a surplus growth in the market. Local manufactures are now adopting new and better characteristics to create an enormous measure of muscular embeds to address the issue in coming fates and also the government is helping to defeat all the difficulties that are been faced in the creation of implants. It is estimated that the COVID-19 pandemic outbreak having a negative impact on the growth of the global minimally invasive gastrointestinal surgical systems market. The growing prevalence of chronic diseases has necessitated the need for a stable healthcare network and adequate emergency medical services (EMS). However certain challenges in Research and Development, loss of patent of the devices may hamper the market growth. In fact, a 60–80% decline in elective procedures in the second quarter of 2020 for Europe and the United States, with an additional 40–50 percent decline in the third quarter is estimated. However, post-pandemic the demand for the minimally invasive gastrointestinal systems will surge exponentially as a result of increased demand for contactless procedure facilities. Moreover, the wider adoption of these systems is expected to increase in order to meet the rising demand for surgical procedures across the globe along with overcoming the shortage of healthcare professionals to perform such surgeries. In the wake of the pandemic, current industry players with a substantial market share which consumed cash-rich and have good management teams would prosper. Making the correct actions would enable businesses to demonstrate preparation and offer end-users reliability.
How COVID-19 Impacted on Neurorehabilitation Devices in Healthcare Industry ?
COVID-19 Impact on Neurorehabilitation Devices in Healthcare Industry OVERVIEW AFTERMATH OF COVID-19 AND GOVERNMENT ROLE The first case of the COVID-19 pandemic was found in Wuhan, China. This pandemic has influenced the whole planet with its major impacts on the economy and businesses across the globe. The COVID-19 spread worldwide in unprecedented ways due to its high infectious and contagious nature. The virus has spread across all regions ranging from North America, Europe, Asia-Pacific, Middle East, and Africa up to South America. The COVID-19 has been declared as a pandemic by WHO due to its increased spread across the globe. Various countries announced the complete lockdown just after the declaration of COVID-19 as a pandemic, such as the U.S., India, Germany, and China, to protect them from the spread of the disease. The government imposed lockdown rules, and it had significantly impacted the market. The neurorehabilitation process makes a possible reduction in impairments and disabilities and eventually improves the life of the patient. Examples of neurorehabilitation devices are invasive stimulators, non-invasive stimulators, brain-computer interfaces, and neurorobotics, among others. Current rehabilitation is supported by advanced methods based on biofeedback, transcranial brain stimulation system, and BCI system. The prevalence of neurological diseases, rise in technological advancement, the emergence of robotic rehabilitation, and the effectiveness of gaming systems in neurorehabilitation are factors that are propelling the demand of the global neurorehabilitation devices market. However, the shortage of skilled personnel, the high cost of treatment, stringent government regulation may hamper the global neurorehabilitation devices market. IMPACT ON PRICE Neurological rehabilitation is a program designed for the treatment of people suffering from a disorder or any injury in the nervous system. The devices include non-invasive brain stimulators, robotic neuro systems, brain-computer interfaces, and wearable devices, among others. Due to the pandemic, there is the delay associated with various types of limitations faced by the manufacturers to fulfill the end product order, which has resulted in the less availability of neurorehabilitation devices in the market and due to which the cost of available devices has increased with the several factors. Also, due to the coronavirus disease (COVID-19) pandemic outbreak, manufacturers are forced to find new contract manufacturers and suppliers for more manufacturing activities to different or new facilities locations that are less impacted by the outbreak. IMPACT ON DEMAND Neurorehabilitation is an important part of the recovery process that has undergone some brain injury. In the COVID-19 pandemic, various charities have worked effortlessly to provide treatment and support to patients suffering from brain injury. During the pandemic, the demand for neurorehabilitation devices was high, but companies were not able to supply the devices to end-users as various restrictions were imposed by the government, such as a travel ban, closed borders, among others. Coronavirus disease (COVID-19) is an infectious disease caused by a SARS-CoV-2 virus, while a large pool of the population is affected by this COVID-19 virus. Coronavirus disease (COVID-19) causes acute respiratory illness ranges from mild to severe pneumonia with respiratory failure. In order to minimize the spread of COVID-19, nearly all the countries have taken action, such as the implementation of lockdown and social distancing restrictions. Due to affirmative restrictions, sudden shrink took place in various surgeries. Moreover, the decrease in the revenue of the key market players depicted in their quarterly results, such as Medtronic, among others, gave evidence of the decline in the demand for the medical device due to the emergence of the COVID-19 pandemic. For instance, · Medtronic reported a decline of 1% in its brain therapies net sales of the financial results of 2020 as compared to 2019. The reduction was largely motivated by the detrimental effects of the COVID-19 pandemic and the subsequent deferral to companies of medical procedures The decline in revenue of brain therapy suggests the detrimental effect of COVID 19 on the neurorehabilitation devices market and hence impacted the demand-supply concept. IMPACT ON SUPPLY CHAIN The consequences of COVID 19 cannot be underestimated. The product and service providers of neurorehabilitation have made efforts by providing services virtually to meet the demands as people were not frequently visiting the hospitals or clinics for the treatment. The COVID-19 pandemic has transformed many organizations’ business environments; supply availability has been hampered by a number of issues, including export and travel restrictions by some manufacturing countries and lockdowns that have forced suppliers to (temporarily) shut down. In various countries, neurorehabilitation units have reduced their number of beds, in-patients and out-patient neurorehabilitation centers are restricted to a particular area in order to tackle the pandemic situation To manage such a critical situation, many organizations are looking forward to improving and diversifying the supply chain model in all aspects. Diversified supply chain model anticipated minimizing the export of medical devices as well as increase end-to-end visibility STRATEGIC DECISIONS BY MANUFACTURERS As the reality of COVID-19 dawned upon the world, the manufactures and production units of the companies in the global neurorehabilitation devices market swiftly planned for strategies to cope with the effect of the crisis. Major players in the market took various initiatives to cope up with the situation. For instance, · In July 2020, Abbott announced that it had received FDA approval for the use of the Patient Controller App on compatible personal Apple smartphone devices. The approval will allow the patient living with neurological conditions to manage their therapy directly from the personal smartphone · In 2019, Mount Sinai Health System announced an innovative tele-neurorehabilitation program for stroke patients. This therapy can be taken by patients while at their homes with virtual backing from clinicians · In 2020, Esko Bionics Holdings, Inc. announced that it had received FDA 501(k) go-ahead to promote its EksoNRTM robotic exoskeleton for patients with acquired brain injury. It is cleared by FDA for spinal cord injury, stroke, or acquired brain injury rehabilitation These strategies helped the company in coping with the pandemic and ensure business operations, minimize the impact of COVID-19, and providing full support to the government in their efforts to combat the disease and help the front-line workers. CONCLUSION The market is expected to decline due to increased restrictions imposed by various governments leading to the closing of non-emergent healthcare facilities, including procedures such as neurorehabilitation procedures. It can be concluded that the COVID-19 pandemic situation has an adverse impact on the market, affecting the price, supply, and demand of neurorehabilitation devices. However, in the crisis call, market players, government bodies, and healthcare organizations are work closely with healthcare professionals, customers, and patients for the betterment of public health. The increasing need of neurorehabilitation devices with increasing number of neurological diseases is expected to drive the market in coming years.
Significant COVID-19 Impact on Nivolumab in Healthcare Industry
COVID-19 Impact on Nivolumab in Healthcare Industry COVID-19 (Coronavirus) has affected the day-to-day life of people and has slowed down the economies worldwide. The pandemic has affected millions of people who either got sick or died due to the spread of this disease. Within a few months, coronavirus disease (COVID-19), which originated from China, became a pandemic, with more than 30 million people being infected till date. There are now numerous vaccines in use. The first mass vaccination program commenced in early December 2020, and as of 15 February 2021, 175.3 million vaccine doses have been administered. There is an added complexity because of COVID-19 diagnosis in cancer patients, particularly while on active treatment with immunotherapy like nivolumab. COVID-19 could cause more harm to cancer patients. In order to prevent the infection from spreading, the patient’s number and new diagnosis have been less during the COVID 19. The COVID-19 pandemic has led to a dramatic loss of human life worldwide and presents an unprecedented challenge to public health, food systems, and the world of work. Still, there is an increase in the demand for cancer treatment with immunotherapy drugs like nivolumab during the second quarter of 2020 with the rise in awareness regarding health and new product launches in countries. IMPACT ON PRICE COVID-19 is significantly decreasing commercial activity in every area of the business sector. The economy has been decreased during the pandemic with the restricted and disrupted supply and sales of products and devices. The cost of medication and treatment of nivolumab has been increased due to the increasing demand for this drug during COVID-19. This contributed to the increased expenses and prices of immunotherapy drugs. Changes in the economy and other factors have caused consequences, including the decrease in the sales of the drug in some countries such as the U.S. With the rise of COVID-19 and decrease in new patients has also contributed to the increased cost and priced of some products and medication. · The price of Opdivo (nivolumab) drug which is a most common therapy treatment for various type of cancer or tumor have been increased to USD 1,172 for a supply of 4 milliliters of injection in 2020 with the rise in demand and increasing patients population in the second quarter of 2020. IMPACT ON DEMAND Global economic development in 2020 has been severely impacted by the COVID-19 pandemic. The COVID-19 has given rise to risks such as a prolonged, significant decline in global demand as well as unfavorable geopolitical and macroeconomic effects. The coronavirus pandemic has provoked many strategical actions among healthcare providers on how to manage cancer patients when faced with the threat of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection. There has been a decrease in demand for nivolumab in some countries like the U.S., whereas many countries have seen an increase in sales with the rise in demand for the treatment and new cancer patients. With the rise in demand for the drug, FDA has provided approval to various drugs related to the immunotherapy nivolumab. For instance- · For the Bristol-Myers Squibb Company, the U.S. revenues of nivolumab decreased to 9% in 2020 due to lower demand caused by declining second-line eligibility across tumor indications and lower demand from COVID-19 (primarily lower new patient starts and patient visits). The U.S. has seen a decrease in sales in the first quarter of 2020. · However, the international revenues for nivolumab were increased up to 7% in 2020 due to higher demand as a result of additional indication launches in some countries with rising cancer patients globally. · In May 2021 -- Bristol-Myers Squibb Company has today announced that the U.S. Food and Drug Administration (FDA) had approved their Opdivo (nivolumab, injection for intravenous use) for the adjuvant treatment of completely resected esophageal or gastroesophageal junction (GEJ) cancer. · Similarly, FDA has approved Opdivo (nivolumab) for treating different types of cancer in many countries via various market players due to the rise in demand for this drug. IMPACT ON SUPPLY CHAIN The pandemic and COVID-19 have affected every business activity in which the supply chain was affected the most. Because of the pertinacious COVID-19 lockdown, sanctions have been forced by administrations of different nations. These limitations and boundaries across the nation’s borders prompted a diminishing stockpile because of restricted materials and labor force and the halting of the assembly line. The COVID-19 pandemic has transformed many organizations’ business environments; supply availability has been hampered by a number of issues, including export and travel restrictions by some producing countries, and the lockdown has forced suppliers to (temporarily) shut down. The supply of nivolumab medication has a slight decrease in sales during the first quarter of 2020, partly due to negative factors mentioned above in connection with the COVID-19 pandemic, which particularly didn’t affect the overall yearly revenue. The supply chain and demand were positively affected by the COVID 19. The sales and supply of the drugs have been increased with the rise in demand for the drugs and diagnosis. Many major manufacturing companies have launched their drugs in different countries to fulfill the demand, and the government has provided approval for the sales of the drug nivolumab. For instance- Despite the pandemic, many market player of nivolumab has increased their sales globally. This is due to the ongoing increase in the patient population and rising awareness regarding their health. · The sales of ONO pharmaceuticals have been increased in the year 2020 as compared to 2019, which is 2656.05 USD Million in 2019 and 2809.23 USD million. · Similarly, sales of the drug Opdivo (Nivolumab) from the manufacturing company Bristol Myers Squibb Company have been increased globally (except the U.S.) from USD 2,860 million in 2019 to USD 3,047 million in 2020. This increase in sales in both of the major market players is due to the increase in cancer patients and the use of drugs in all areas of cancer. There is an increase in the sales of this nivolumab with the rise in prevalence of disease and early diagnosis & treatment. STRATEGIC DECISIONS BY MANUFACTURERS To deal with the COVID-19 outbreak challenges and increasing demand for the drugs, many market players are creating new strategies such as new product development, telemedicine, and a different program to support patients and to raise their sales. It is predicted that these strategies are anticipated to escalate up the company revenue and its growth in the forecasted period. The government has provided drug FDA approvals of nivolumab for the treatment of cancer. For instance, · In May 2020, Bristol Myers Company announced that Opdivo (nivolumab) 3 mg/kg plus Yervoy (ipilimumab) 1 mg/kg (injections for intravenous use) was approved by the U.S. Food and Drug Administration (FDA) for the first-line treatment of adult patients with metastatic non-small cell lung cancer (NSCLC). · There are several ongoing potentially registrational studies that have been conducted by different manufacturing companies for Opdivo for the treatment of different tumor types and disease areas, in combination with various anti-cancer agents · Also, there are various ongoing clinical trials conducting on nivolumab with the combination of various anti-cancer agents and others to treat various types of cancer to decrease the demand for cancer treatment and to provide patients with more advanced drugs. For instance · In Japan, South Korea, and Taiwan, ONO pharmaceuticals are co-developing this drug nivolumab with the Bristol Myers Company CONCLUSION As the pandemic of COVID-19 resulted in several restrictions throughout the borders, still, manufacturers and market players were able to manage their sales and revenue of oncology and drug nivolumab. Various manufacturers allowed their workers to work in a clean and safe environment so as to boost up the production at various manufacturing facilities across several regions of the world, thus, helping them to maintain a continuous supply chain with the increasing demand. Market players have come up with better strategies which have also created a positive impact on the growth of the nivolumab market globally.