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How COVID-19 Impacted on mHealth in the Healthcare Industry ?


COVID-19 Impact on mHealth in the Healthcare Industry
The COVID-19 pandemic has made an unprecedented effect on daily lives as well as the global economy. The impact on the healthcare sector has been seismic too and a significant burden is created on already strained healthcare systems across the world. As the overworked healthcare providers are grappling with constant rise in number of cases, patients are looking towards digital technologies for aid.
COVID-19 outbreak has also made healthcare professionals to look for alternative methods to traditional systems and processes. This is leading an expedited adoption of mHealth across the industry both from providers and consumers.
During the pandemic, several healthcare systems have bifurcated healthcare requirements into essential and non-essential based on urgency and overall requirement for care. As the non-essential requirements are given less priority during the pandemic, patients are resorting to mHealth solutions. This is augmenting the adoption of mHealth apps across a variety of therapeutic areas.
As the pandemic subsides, the healthcare industry is expected to witness drastic structural and procedural changes as a large number of people become sceptic of visiting closed spaces with high risks of infection. Hence, it can be concluded that the COVID-19 outbreak is expected to play a significant role in the digital transformation of healthcare industry.
The availability of healthcare apps is growing which are commonly referred to as mHealth (mobile health) apps. These apps are easy to download on smartphones, can be linked with wearable technology and assist the users in disease prevention and overall health management. The COVID-19 outbreak has increased the reliability of patients on mHealth apps in order to take an active and informed role in their own healthcare.
The easy availability of smart phones and the need for alternative ways to take care of health presents a notable opportunity for mHealth apps providers to expand features and usage. Companies are focusing towards connectivity improvements and interoperability of mHealth apps in terms of data storage and data transfer to healthcare providers. This level of data collection is also useful for tracking overall population health. Before the availability of this kind of data, health authorities were dependent on tedious population studies that had several limitations. MHealth has the capability to provide real time population health information through mass data collection. As a result, healthcare authorities across the world are taking initiatives for MHealth. The below chart shows the percentage of countries taking mHealth initiatives across various WHO regions:

COUNTRIES UNDERTAKING MHEALTH INITIATIVES ACROSS WHO REGIONS


The COVID-19 pandemic has highlighted the value of digital approaches more than ever before that are designed to help health professionals and the public to maintain communication about a disease and stay updated with fresh information that will enable better strategic planning.
The market is flooded with mHealth apps and consumers have a lot to choose from. However, there is significant variation in their capabilities. Till now, the functionalities of these apps are narrow primarily due to mild demand and are restricted to providing information only. As the demand and the number of apps are increasing in the market, multi-functionality is becoming common. In order to enhance, consumers experience in managing their health, multi-functionalities for online appointment scheduling, medication reminders, online consultation and sending diagnostic test results to healthcare providers for analysis, review and action. These apps are superior in assisting consumers in managing and monitoring their health as compared to the information and education apps.
Currently, there are no authorities to check on the efficacy and accuracy of these apps leading to difficulties for healthcare providers to access the validity of data received through these apps. The problem is worsened with the mushrooming of mHealth apps leading to consumers self-determining the best app for their use by trying an overwhelming number of options without consent or consulting from health professionals. However, privately funded third party organizations are putting efforts to establish rating and evaluation systems that will indicate the appropriateness of these apps. Few of these organizations are Happtique, HealthTap, PatientView, Wellocracy and AppScript. These ratings are primarily based on user ratings, clinical ratings, and proprietary scoring methods. As a result, few products have low functionality scores but high rating due to scoring factors such as high clinical or patient ratings.
As the position of mHealth apps become more important in the aftermath of the COVID-19 pandemic, national health authorities are expected to launch rating and licensing platforms for higher efficiency and reduce crowding in the market.
For instance,
· The United Kingdom National Health Service (NHS) has expanded their publicly funded prescribing platform to include clinically safe consumer apps.
The sudden outbreak of COVID-19 has highlighted the importance of population health monitoring systems and burden on healthcare systems. mHealth has the potential to meet these requirements. Few areas in current healthcare landscape where mHealth can be useful are listed below:
Reducing physical contact: Medical distancing has played an important role in reducing the infection rate of the novel virus. Key healthcare authorities such as the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) have advocated for minimal physical contact between the healthcare providers and patients. Since providers work near infected patients, they might likely contact the virus or act as a carrier which can be further spread to a healthy patient. With the help of mHealth apps, patients can share required data with physicians without actually visiting the healthcare providers. This will not only help in reducing COVID-19 infection but several other types of infections that a patient might contact in a healthcare establishment.
mHealth services are playing an important role in reducing healthcare-specific COVID-19 transmission. Due to sudden burden on healthcare facilities, treatments are given priorities on the basis of urgency. Moreover, patient not infected with COVID-19 virus do not want to visit these facilities. In this case, to treat mHealth is proving to be of immense use in several therapeutic areas including cardiology, dermatology, diabetic care and others by enabling high-quality remote care and reducing contact.
Population Health Management: The uncontrollable surge of COVID-19 infections has highlighted the need of crowdsourced health monitoring by tracking the infected. Existing surveillance systems have drawbacks associated with flexibility and amount of reliable information. mHealth offers the ability to collect real time information from a significant share of the population making the information more reliable and easy to use as compared to existing systems. mHealth can also be used by healthcare agencies to track the hotspots and carriers by analyzing travel routes which in turn provides information regarding the probability of catching an infection. Hence, health agencies can better manage health population by crowdsourcing disease monitoring using mHealth.
Health Information Exchange Improvement: The lack of appropriate health information exchanges has shown that interoperability of patient data is very important. The importance of other data types apart from core patient data including an individual’s offline and online activity has helped immensely in tracking of the spread of COVID-19 pandemic. In the aftermath of the virus, HIEs are expected to become open and un-localized. The infection has showed that in similar times, there is a crucial need for information to stop the spread of infection and save lives. The need for easy, seamless communications in healthcare is also important.
Health Gadgets: The COVID-19 infection increased the wellbeing awareness and anxiety across the world. It has instilled a sense of fear of infection that has led to increased adoption of smartphone applications and wearables. mHealth apps and complementary wearables play a crucial role in gaining information and getting a sense of protected. They provide accurate feedback on bodily functions including blood pressure and body temperature which helps in tracking health.
Several companies are using mHealth technology to track, test, and treat COVID-19.
For instance,
· Google and Apple have announced that the companies are planning to launch APIs to provide interoperability between iOS and Android products. The companies are also aiming at enabling deeper data integration with the mHealth apps for public health initiatives of the government. To achieve the same, they are developing Bluetooth-based contact training features.
· Walgreens announced expansion of its telehealth program including COVID-19 risk assessment. The platform meets the demands for social distancing and includes a website and mobile health application powered by Microsoft Healthcare Bot on Microsoft Azure. The platform helps patients to connect with nurses and doctors as per requirement.
· SCP Health and SOC Telemed declared their partnership to provide scalable emergency service and hospital medicine through telemedicine that will enhance the critical capability of healthcare facilities.
· Jefferson Health system and LifeLink have announced partnership to launch Jefferson’s chatbot across LifeLink’s 14 Philadelphia locations. The AI-based chabot will aid users in pre-screening of coronavirus outbreak and the right approach of their treatment in case they are infected with the virus.

CONCLUSION

The post-COVID-19 healthcare is expected to see transformation of processes with high inclusion of mHealth.
For instance,
· Primary care and management of several non-communicable diseases are expected to be shifted to digital mode. Several countries including England, have begun to embrace telehealth for delivery of primary care and are undertaking a digital first approach for overall healthcare provision.
The sudden outbreak did not leave much scope for prompt action on impact. However, the post-COVID-19 world will witness increased adoption of mHealth as the new normal. Applications of emerging technologies such as 5G, AI, IoT, and others will be expanded. National governing bodies will emerge to manage mHealth approaches. Focus on precision health will also increase in both personalized and predictive health. The utilization of digital technology will increase for empowering patients to self-manage themselves, especially in case of non-communicable diseases.
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The impact of covid-19 majorly impacted the organizations if the revenues loss projections do not change, this will leads to temporarily or permanently shut down of small and middle foundations and organizations. IMPACT ON SUPPLY As the epidemic intensifies, supply chains can be at significant risk due to over-located locations that can potentially be disrupted. The supply chain of drugs, devices, and services has been disrupted. The spread of COVID-19 makes it difficult for governments to use these drugs; the availability of these systems faces constant challenges due to their components of use and limited initial needs. Moreover, as there is no cure for the disease, only physical activities/therapies may suppress the symptoms also affected by pandemics. 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It is expected that the strategic decisions of these companies will provide significant opportunities for market participants operating in the Niemann-Pick Disease market. For instance, · In July 2020, Abbott announced that it had received FDA approval for the use of the Patient Controller App on compatible personal Apple smartphone devices. The approval will allow the patient living with neurological conditions to manage their therapy directly from personal smartphone. · In May 2020, Philips, a global leader in health technology, joined forces with the American Telemedicine Association (ATA) to help further the adoption of telehealth across the industry, demonstrating its commitment to connecting care across acute, post-acute, and home care settings. The continued collaboration spotlights telehealth's growing adoption and momentum amidst COVID-19 and the need to convey the exponential shift to telehealth capabilities. · In U.S., NIH supports the research survey of “CURE EPILEPSY ORGANIZATION” to examine the impact of Covid-19 on Rare Disease Community. The survey includes more than 200 rare diseases including the brain, immune system disorders, heart, lungs, brain development diseases, and more. CONCLUSION As this pandemic situation has resulted in many restrictions in different places around the world, still the market players of dealing in rare diseases therapy and services were able to manage their service stock. Different companies dealing in metabolic diseases therapy services were finding out their own way to deal with this pandemic situation. The government and companies around the globe are working together and have issued advice for those undergoing therapies centers during these unprecedented times during COVID 19 lockdown around the world. The supply chain was destroyed, but several steps were taken by the government and companies, which will help them, get their needed output for therapy service. By increasing the material price, the companies can maintain their overall revenue. Thus, different foundations, organizations,, and services center markets are finding ways to deal with this pandemic situation. Figure 1: Relationship between Coronavirus and Lysosome storage diseases : Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway
Why And How To Use A Niacinamide Serum
Niacinamide may not get as much attention as retinol and vitamin C, but it is a skincare powerhouse that deserves equal recognition. It is the definition of a multitasker, offering a host of distinct benefits that make it a good choice for a wide range of skin types and complexion issues. However, incorporating it into your current skincare routine might sound difficult. Is it OK to use niacinamide along with vitamin C and/or retinol? Is hyaluronic acid a viable alternative? We weigh in on everything you need to know about using niacinamide. What is niacinamide, exactly? Simply put, it's a B vitamin, one of two forms of vitamin B3, and it participates in a number of critical cellular operations in the skin. What benefits does it have for the skin? Buckle your seatbelts, because this is going to be a long list. Niacinamide is a fantastic treatment for acne-prone skin. Niacinamide reduces sebum production, which can help prevent acne and shine. The vitamin is also known for its anti-inflammatory qualities, which aid in the treatment of acne and other skin conditions such as eczema. Niacinamide helps to build the skin barrier, which is advantageous to people who have eczema or sensitive skin. It is also an efficient skin lightening agent, treating hyperpigmentation by blocking pigment transfer from pigment-producing cells known as melanocytes to skin cells on the surface where discoloration is visible. As if that wasn't enough, there's evidence that niacinamide can help to reduce wrinkling and photoaging by maintaining cell function and repairing DNA damage. To summarise, niacinamide has very few limitations. Is it OK to mix niacinamde and retinol? Yes! In fact, retinol and niacinamide are recommended together for faster effects. The soothing characteristics of niacinamide can also assist to alleviate the unpleasant side effects and irritation that usually accompany retinol's wrinkle-fighting effectiveness. Is it safe to combine with other ingredients? Yes, as a general rule, which is why it's found in many skincare products and is easy to incorporate into your present routine. Niacinamide is frequently coupled with salicylic acid, a beta-hydroxy acid typically found in acne products, due to its acne-fighting qualities. Combining niacinimadie's oil-removal properties with salicylic acid's ability to break down excess oil is an effective way to keep pores free and breakouts at bay. Niacinamide is an ideal choice for combining with alpha-hydroxy acids, which are chemical exfoliants that can cause skin irritation, due to its anti-inflammatory and skin barrier-strengthening effects. Because the AHAs exfoliate the dead skin cells that would otherwise make it impossible for the niacinamide to enter, combining them boosts the efficacy of the niacinamide. Finally, because niacinamide and hyaluronic acid can both help with dry skin, they are frequently mixed. What is the one thing that the jury is still out on? Vitamin C. Because vitamin C might inactivate niacinamide, the applications should be separated by 15 minutes. In truth, the two would have to be heated in order to interact negatively, and more and more cosmetics are combining the two in skin-brightening formulations. The bottom conclusion is that if you utilise a product that contains both vitamin C and niacinamide, it was most likely specifically designed to work together. If you're using two different products that include these chemicals, wait 15 minutes between applications or use one in the morning and the other in the evening. Should I use niacinamide? Sure, in a nutshell. One of the nicest aspects of niacinamide is not only the vast list of benefits it offers, but also how well it is tolerated, particularly by those with sensitive skin. This makes it an enticing choice for those whose skin is sensitive to more common acne or skin lightening agents like benzoyl peroxide or retinoids.
Significant COVID-19 Impact on Non-Small Cell Lung Cancer Diagnostics in Healthcare Industry
COVID-19 Impact on Non-Small Cell Lung Cancer Diagnostics in Healthcare Industry The novel coronavirus has profoundly impacted all fields, including healthcare, medical device services, automotive, pharmaceutical and many others. This pandemic has led to shutdowns of mass production and disruptions in the supply chain that have impacted the economies of virtually every nation in the world. The pandemic also affected the non-small cell lung cancer diagnostic industry. The patient's fear of contracting the virus compels patients to stay home instead of undergoing diagnosis and treatment. During the COVID-19 pandemic, countries worldwide witnessed a large number of patients suffering from COVID-19 and post COVID-19 complications such as cardiovascular disease, diabetes and kidney problems. As the COVID-19 cases were rising, the healthcare system had shifted its focus in curbing the disease, thereby delaying diagnosis and treatment of other chronic conditions as cancer. Thus, a negative impact is expected on the non-small cell lung cancer diagnostics market due to the pandemic scenario As a result, the hospitals and clinics were filled up with COVID-19 patients and less preference was given to non-small cell lung cancer patients. Moreover, limited access to clinics, social distancing, the lockdown of the population, which results in a slow-down in patient flow and referrals, has also impacted the market growth. However, with the cases decreasing in number and increase in vaccination against COVID-19 across the globe, the market for non-small cell lung cancer diagnostics market may get a boost due to some relaxation in COVID-19 cases, which will result in increased demand for non-small cell lung cancer diagnosis with patients coming forward to clinics and hospitals for treatment. IMPACT ON DEMAND Various screening, diagnostic and surgical procedures were restricted and at hospitals and cancer treatment centers, which resulted in disruptions in the non-small cell lung cancer diagnostics market. However, even during the pandemic, the lung cancer cases were subsequent, which is expected to increase the demand for non-small cell lung cancer diagnostics market. For instance, · According to World Health Organization (WHO), in 2020, lung cancer accounted for 2,206 771 deaths among both sexes. The lung cancer statistics include both small cell lung cancer and non-small cell lung cancer. About 13% of all lung cancers are small cell lung cancer and 84% are non-small cell lung cancer. This proves an increase in the number of non-small cell lung cancer patients even during the COVID-19 pandemic. Moreover, according to the American Cancer Society, Inc., lung cancer patients are likely to get infected with coronavirus because of the changes in their immune system that control their body's defense systems. For instance, · According to a study published in PubMed, patients with lung cancer are at an increased risk of becoming infected with the virus and experience higher morbidity and mortality than the general population Thus, having cancer such as non-small cell lung cancer may also increase the risk of severe illness from COVID-19 as the cancer therapy treatment reduce the immune system of the body. . This has increased the demand for non-small cell lung cancer diagnostic tools, especially in cancer-dedicated hospitals and surgical centres, where all the patients of non-small cell lung cancer-related problems are treated. Thus, with the increased lung cancer cases, the demand for non-small cell lung cancer diagnostic will increase in the coming years. IMPACT ON SUPPLY CHAIN The supply chain was widely affected by the COVID-19 pandemic as acute restrictions and lockdowns produced many urgent situations in the early days of the pandemic, which needed immediate attention. The supply chain disruption has transformed many organizations' business environments, including the supply chain of non-small cell lung cancer diagnostics market. The supply chain disruption impacted the Asia-Pacific region initially, especially the demand from China due to challenges from restricted movement and quarantine period. For instance, · According to the FDA, 63 manufacturers representing 72 facilities in China that produce essential medical devices face obstacles in manufacturing medical devices and their supply, owing to citing workforce challenges and the necessary quarantine of workers. Moreover, closing borders of various countries is anticipated to diminish the supply chain business environment, as it may hamper export of the medical supplies To minimize supply chain crises, the FDA has been firmly monitoring the supply chain with the assumption that the COVID-19 outbreak may adversely impact the supply chain of medical products, including shortages of critical medical products in the U.S. or potential disruptions in supply chains. Many organizations and countries are looking forward to improving and diversified supply chain models in all aspects to manage such a crucial situation. A diversified supply chain model anticipated minimizing the export of medical products as well as increase end-to-end visibility. For instance, · The Brazilian government published a resolution eliminating import taxes on 141 medical products and hospital equipment · The European Commission made a decision for helping Member States affected by the pandemic to suspend customs duties and VAT on medical devices temporarily · Federal indirect tax body the Goods and Services Tax (GST) Council of India has decided to cut taxes on medical supplies IMPACT ON PRICE The coronavirus disease (COVID-19) pandemic does not significantly impact the global non-small cell lung cancer diagnostics market. But it is estimated that if COVID-19 continues to spread for a prolonged period, then the demand for non-small cell lung cancer diagnostic equipment and devices will highly upsurge for top importer countries. For therapies and the diagnostic United States solicit the huge number of medical devices, followed by China and Japan. For instance, · According to the General Administration of Customs (GAC), China's exports of medical machinery and devices increased 40.5 percent in 2020 compared to the previous year, reaching USD 18.138 billion · According to the World Trade Organisation, the U.S. imports and exports of medical goods increased by 16 %, reaching USD 1,139.00 billion in value Henceforth for diagnosis, dependency of these countries highly increases on other exporters and many countries solely depend on China and the U.S. for the non-small cell lung cancer diagnostic equipment. Consequently, this may lead to a rise in the overall non-small cell lung cancer diagnostic cost. This increase in the price of the non-small cell lung cancer diagnostic may hamper the market growth if it continues to be the same. Additionally, if the lockdown continues to stretch for a long period, then import of non-small cell lung cancer diagnostics market is estimated to get more restricted, which may further lead to a rise in the price of the these devices CONCLUSION It is estimated that the COVID-19 pandemic outbreak has significantly impacted the growth of non-small cell lung cancer diagnostics market as the rising cases of COVID-19 worldwide the healthcare system had shifted its focus in curbing the disease, thereby resulting in the delay of diagnosis and treatment of non-small cell lung cancer. Thus, a negative impact is expected on the non-small cell lung cancer diagnostics market due to the pandemic scenario. However, with the increase in lung cancer patients worldwide, the demand for non-small cell lung cancer diagnostics will increase in the coming years. Moreover, poor lifestyle, smoking, alcohol consumption, lack of physical activity and other factors will contribute to the incidence of chronic disease such as lung cancer, including non-small cell lung, which is anticipated to increase the global non-small cell lung cancer diagnostics market in the coming years.
Lose weight Quickly: Just how To Make It Happen Safely and securely
Power training and bodyweight coaching exercise help you stay lean because they build muscle as well as raising your metabolic rate, even if you’re not working out. There is however one other form of exercise I didn’t talk about, as well as that is strength-centered weight training exercise. Eating a lot of convenience-sort food items like sausages and fast food when you're on the run can impede your fat loss. You ought to psychologically make on your own to satisfy these long-term obstacles prior to beginning your vacation to weight-decrease. More modern day Federal Institution for Health and also Proper care Quality assistance suggests that a 3Per cent weight-decrease is desired as well as needs to be the achieve a 12-full week assistance 1. Quite basically, your weight-decrease ambitions should be distinct, quantifiable, feasible, practical and tangible. To shed visceral extra fat, you ought to acquire inside the appropriate food, consume lots of drinking water and also do lots of physical physical exercise. Visceral body fat stands out because the kind of body fat that encompasses the internal organs in your very own abdomen and makes your belly appear bigger than it might really be. A 5-year examine on minorities ranging in age from 18 to 81 showed that in case you include dietary dietary fiber to the diet plan, as well as combine it with physical physical exercise, you are able to speed up visceral weight-reduction. By carrying out this, you won’t have to wonder precisely what to consume for the following meal, or be worried about producing a calorie debt. Operating aids you protect a calorie debt by expanding the amount of calories you burn. It's possible to enhance your calorie debt and your rate of body fat decreasing - no less than theoretically - by consuming much less. Research from the American Heart Organization indicates that skipping foods for body fat decreasing ultimately backfires. Practical Fat burning Targets: A Real Possibility Verify You Need Even however, if we made a decision to dance to get leaner, we must set a goal. For example, it could be a lot more realistic establishing a objective of ingesting some fruit every single day rather than one sweet object. Each time we established a objective, we attempt to calculate the near future, which is absolutely difficult. Which can be undoubtedly a issue you need to think about when creating Revitaa Pro approach. Some people call it “deep belly fat,” and it’s been linked to all kinds of problems including insulin resistance, coronary disease, diabetes, and cancer. Cortisol can also make your insulin level spike triggering your blood sugar to drop and making you crave sugary or unhealthy goodies. Yet another consists of fasting every day for 16 hours and also eating all your food within an 8-hour period. Other cells are then within a situation to use these fatty acids as gasoline. Omega 3 fatty acids happen to be in greasy fish, also as consuming 2-3 helpings of fish every week is required. Coconut oil makes up higher essential essential fatty acids of the moderate length generally typically generally known as medium-sequence triglycerides which may improve satiety correct shortly after food. With balanced meals choices and a little exercise if you’re capable, you might be in a position to achieve your body fat reducing and physical fitness goals each in the brief and long-lasting. In order to reduce bodyweight, different methods, like diet program, actual physical physical activity, medication therapy, also as surgical treatment have currently been advised. Exactly how several calories you need to consume a day to reduce bodyweight will rely on several components, also as your age, sex, accurately how significantly weight you need to decline, and your action level. Revitaa Pro boosts your metabolic process and also calms your opinions, empowering you to rest properly, that is furthermore vital from the extra fat decrease method. Revitaa Pro though a pretty new extra fat decrease supplement inside of the town but with offers to aid you drop more lbs and also raise your metabolic process in spite of how old you are or full system framework.
How COVID-19 Impacted on Oral Care in Healthcare Industry ?
COVID-19 Impact on Oral Care in Healthcare Industry OVERVIEW The COVID-19 pandemic has posed a complex challenge in front of several healthcare companies and proved to be an unprecedented global health threat. This global pandemic has emerged in December 2019 which has been proved as a global pandemic by WHO in March 2020. With the development and introduction of novel coronavirus vaccine, COVID-19 cases have been declined but with the development of mutant coronavirus strain, the overall COVID-19 cases have been surged and are increasing at a rapid rate in India, and the U.K, and other European countries. The most common symptoms associated with this include cough, fever, diarrhea, sore throat, and loss of smell or taste. Patients affected with COVID-19 are at increased risk of developing hepatic manifestations and also experiences damage to liver tissues. COVID-19 has led to the closure and reduced hours of dental practices except for emergency and urgent services, limiting routine care and prevention. Dental care includes aerosol-generating procedures that can increase viral transmission. The pandemic offers an opportunity for the dental profession to shift more toward non-aerosolizing, prevention-centric approaches to care and away from surgical interventions. Direct effects of COVID-19 on oral health include ageusia (an official symptom of COVID-19) and case reports of vesiculobullous lesions and necrotizing periodontal disease. oral care product has a wide portfolio such as breath Fresheners, Mouth Wash, Dental Floss, among other products. The Article here shows the impact of COVID-19 on the oral care market. IMPACT ON PRICE As the mouth is an important place for bacterial colonization due to which it is necessary to use the product for oral hygiene. With the sudden increase in COVID-19 cases, people's concerns for better health had also increased and the link between oral health and COVID-19 infection also expand the health to oral. As India relies on China for 70% of API’s intermediates and bulk ingredients, COVID -19 is expected to hike the price of the ingredient used for an oral care product For instance, · In the year 2021, As Proctor & Gamble announced the third-quarter result in which the net sales increase by 5 %, and also mentioned that they are planning for a price hike in certain product divisions. This step is taken seeking to recover the revenue loss during COVID-19. · According to GlaxoSmithKline plc, the cost of dental consultation and treatment was cited as the concerning factor IMPACT ON DEMAND The coronavirus has affected the various regions of the world and caused the widespread closure of companies and local manufacturing plants. This lockdown and isolation have adversely impacted global economic activity. As studies around the world have shown the improving oral hygiene is expected to increase the chance of generating demand for the product. THE IMPACT OF COVID-19 INFECTION ON ORAL CARE The rising awareness of oral hygiene COVID-19 has increased the demand for a product requires for oral care as the increasing studies for SARS-COV-2 indicated that proper oral hygiene has been reported to decrease the chances of infection which increases the demand for mouth wash, oral povidone solution, novel gargle solution. · However, due to restrictions and aims to reduce COVID-19 transmission, 30% of respondents had visited a dentist less frequently during the pandemic The second cause of increasing demand for oral care products is that approximately 90% of the product used in oral care are over the counter which can be added as the plus point in maintaining the demand for oral care products. The market players in oral care are also focused on the research to bring novel products to interstate commerce. For instance, · Microbac Laboratories, an independent and internationally accredited testing facility worked on behalf of Unilever Research Laboratories, has found that rinsing with mouthwash containing CPC Technology for 30 seconds is effective in reducing the viral load of SARS-CoV-2, the virus that causes Covid-19, by 99.9%. This type of research surge the demand for the oral product · Colgate-Palmolive President mentioned in an interview that they have seen elevated demand for oral care related to viruses, which also boosted the innovative growth related to a premium product This suggests that the increasing prevalence of COVID-19 poses precautionary measures due to which the global population started to take concern for their health hence enhance the demand for oral care. This thus signifies that COVID-19 is accelerating the demand of the oral care market. IMPACT ON SUPPLY The COVID 19 pandemic has affected and badly disrupted the global drug supply chain due to the continuous shut down of manufacturing facilities and restrictions imposed by the government over import and export activities. As per global sources, it was found that the beauty care business is still facing a crisis due to COVID-19. However, oral care market players are in a strong position. The two main leaders Colgate-Palmolive and Johnson and Johnson had seen a lift in sales in Q1 2020. Colgate-Palmoliva has net sales of USD 415 million for Q3 2020, up by 5.5% from the previous year. The surge of demand for oral care increased during COVID-19 however, the global restriction, and state-wise travel restriction has caused challenges for the market player. Moreover, there are many local players also in the oral care market that continued to fulfill the demand in case of any disruption. Oral care is categorized under essential need products which leads to the easy flow of these products. The main challenges during the pandemic is the supply of API’s and Ingredient or excipient used in toothpaste, as China holds the major share in API’s and other chemicals used in oral care and global restriction has somehow affected the supply chain for these products too. This, thus signifies that due to continuous lockdown and several restrictions by government authorities the companies and patients are facing disruption of the supply chain for oral care. However, oral care is categorized under essential care which lowers the effect of supply chain disruption during COVID-19. STRATEGIC DECISIONS OF MANUFACTURERS Collaboration, agreements, strategic initiatives, product launches by market players such as Colgate Palmolive, Hindustan Unilever among others in the oral care market will help them to expand their product portfolio and to provide appropriate products to the consumer. This in turn will lead to increased product sales and hence will put a positive impact on the overall company’s revenue. Oral Care product manufacturing companies are taking so many strategic decisions to cope up with the current scenario of COVID-19. The companies engaged in the manufacturing of toothpaste, mouth wash, gargle solutions among others are adopting several initiatives to accelerate the development of newer products and efficiently supply the product to different end-users. Companies have done collaboration and product launches between 2019 -2020 which supports the sustainable growth in the oral care market For instance, · In September 2020, Colgate Palmolive launched as first-ever vedshakti mouth protect spray, seeking their focus on oral hygiene during COVID-19. · Hindustan Unilever also planned to launch a mouth wash with 99 % in reducing SARS-COV-2 virus and has recently shared the preliminary data. · In April 2020, GlaxoSmithKline Consumer Healthcare Limited (India) merged with Hindustan Unilever Limited (HUL), with HUL responsible for the distribution of GSK’s Consumer Healthcare brands in India, including its leading oral healthcare brand, Sensodyne. · In April 2020, Perrigo Company plc (Ireland) completed the acquisition of the oral care assets of High Ridge Brands (US), which includes Dr. Fresh, LLC. · In December 2019, Colgate-Palmolive Company launched Colgate Optic White Renewal Tooth Paste. · In 2020, Colgate-Palmolive comes up with a recyclable toothpaste tube which will increase the interest of the population and surge the demand for the product leading to growth in revenue of the company Thus, companies operating in the oral care market are adopting several strategies, including collaboration, agreements, acquisition, and market expansion to enhance their business. These strategic decisions by the companies are expected to provide significant opportunities for the market players operating in the oral care market. CONCLUSION As the pandemic of COVID-19 has resulted in several restrictions throughout the borders but still, manufacturers of oral care can manage their stocks. Various manufacturers have allowed their manufacturers to work in a clean and safe environment to boost up the production of oral care categorized under essential need products at various manufacturing facilities across several regions of the world helping them to maintain a continuous supply chain. However, a decrease in doctor’s visit has impacted the market but the majority of products used in oral care are over the counter product which leads to continuous demand for oral care, and by raising the prices the companies are gaining extra profit which is helping them to combat the negative effect on overall revenue.
CBD for Sleep, CBD Benefits, Side Effects, and Treatment
People have long used the cannabis plant for medicinal and recreational purposes. Compounds called cannabinoids in the plant are responsible for the effects on the brain, and the two most abundant of these are tetrahydrocannabinol (THC) and cannabidiol (CBD). People use CBD for a variety of reasons, including reducing seizures, anxiety, and pain. Some studies have demonstrated that CBD may also be a sleep aid. In this article, we look at whether it works and any associated risks. What the research says In the last decade, growing public interest in the benefits of marijuana, and CBD in particular, has encouraged researchers to study its effects. Early studies indicate that high dosages of CBD may support sleep. One investigation found that, compared with a placebo, a CBD dosage of 160 milligrams (mg) increased sleep duration. The researchers also concluded that the placebo, 5 mg of the insomnia drug nitrazepam, and 40, 80, and 160 mg of CBD helped the participants fall asleep. The stress hormone levels of cortisol are typically peak in the morning, but people with insomnia may have high cortisol levels at night. Independent of insomnia, having high cortisol levels at night is associated with an increased nighttime awakening. In one study on the effects of CBD, researchers found that cortisol levels decreased more significantly when participants took 300 or 600 mg of CBD oil. These results suggest that CBD affects the release of cortisol, possibly acting as a sedative. A more recent analysis of CBD and sleep recruited 103 participants who had anxiety or poor sleep. The researchers studied the effects of CBD combined with those of other prescribed medications. The CBD dosages ranged from 25–175 mg. The researchers found that 25 mg was the most effective dosage for anxiety and that addressing troubled sleep required higher dosages. During the 3-month study, the investigators followed up with the participants monthly. At the first follow-up, 66.7% reported an improvement in sleep, but 25% had worsened sleep. 56.1% of the participants reported improved sleep at the second, but 26.8% had worsened sleep. The researchers conclude that although CBD might help people sleep in the short term, the effects may not be sustained. Side effects and other risks of CBD Overall, the available evidence suggests that CBD is well-tolerated. Some people report fatigue and mental sedation with CBD use, but researchers believe this may be related to the dosage. Taking 10–400 mg of CBD per day for an extended period and by different routes did not have a toxic effect on participants in a large retrospective study. Even dosages of up to 1,500 mg per day were well-tolerated, other researchers report. However, determining whether there are long-term risks of CBD use will require further studies. So far, no reports of lethal CBD overdoses exist. Some researchers may be concerned about CBD abuse, but information on significant complications is limited. One study indicates that dosages of 400–700 mg of CBD, which is considered high, can aggravate cognitive deficits in people with schizophrenia. Combining CBD and THC may, however, improve cognition. Researchers do report that CBD may cause other adverse effects, including: alterations of cell viability in studies conducted in cell cultures decreased fertilization capacity inhibition of drug metabolism in the liver reduced activity of P-glycoprotein and other drug transporters If these effects on drug metabolism and transportation are confirmed, it would indicate that CBD interferes with other medications. Overall, more research is necessary. Still, it is suitable for anyone who wants to use CBD to speak with a healthcare provider first. Check out the best CBD for sleep at Sweet Dream Beauty website.
How COVID-19 Impacted on Parenteral Nutrition in Healthcare Industry ?
COVID-19 Impact on Parenteral Nutrition in Healthcare Industry The COVID-19 pandemic has influenced the whole planet with its major impacts on the economy and businesses across the globe. The COVID-19 spread worldwide in unprecedented ways due to its high infectious and contagious nature and lack of availability of its vaccine. As a result, the greatest medical challenge in the 21st century is yet to be faced by physicians worldwide. Though the emergence of the virus can be traced back to Asia, many European countries along with the U.S. have been struck massively by the pandemic. The virus has spread across all regions ranging from North America, Europe, Asia-Pacific, Middle East, and Africa up to South America. The COVID-19 has been declared as a pandemic by World Health Organization (WHO) due to its increased spread across the globe. After the declaration of the pandemic, various countries announced the complete lockdown such as India, China, and other Asian countries to decrease its spread. According to the latest situation report by World Health Organization (WHO) stated 175 million cases of Corona have been reported globally and 4 million patients are dead due to the coronavirus. On a slightly positive note, a total of 158 million people have recovered and a total of 2 million vaccine doses have been administered as well. Parenteral nutrition is the medical term used for infusing a specialized form of food through a vein, intravenously. The objective of the treatment is to correct or prevent malnutrition by providing liquid nutrients, including carbohydrates, proteins, fats, vitamins, minerals, and electrolytes. Parenteral nutrition is used when the patient's gut cannot be used to absorb nutrients, the nutrition then must be delivered into the patient’s bloodstream, bypassing the gut. The reason for this type of feeding includes blockage of the gut, Perforations of the gut, parts of the bowel are diseased, or when a large part of the gut has been removed. COVID-19 has negatively impacted the market as trained professionals are required for the administration of such nutrition. But owing to the imposition of lockdown by the government, such administrations can’t be done that impacted negatively. The pandemic has affected the parenteral nutrition market in three ways: by directly affecting production and demand, by creating supply chain and market disruption, and by its financial impact on firms and financial markets. For instance, · In October 2020, the American Society for Parenteral and Eternal Nutrition issued the guidelines to update the use of filters for parenteral nutrition. The guidelines aim at reducing exposure to particulate matter during parenteral nutrition (PN) therapy by updating In-line intravenous filters. IMPACT ON DEMAND With the lockdown, all hospital admissions were stopped except the COVID-19 patients. Since the pandemic, lockdown situation the economic growth of the country is declining. And the manufacturing units for various items that are considered non-essential are shut down due to the non-availability of manpower. The pandemic has caused major destruction in the delivery of healthcare products across the world. It has posed limitations on many patients to access standard health services such as visits to healthcare professionals, medications, and diagnosis. It has adversely impacted the ability of patients and practitioners to adhere to treatment guidelines. Moreover, the demand for parenteral nutrition and growing awareness about current and new products is also fueling the market. For instance, · Otsuka Pharmaceutical Co. Ltd stated that in the pharmaceutical business, official requests to stay at home and urban lockdowns have led to a decrease in outpatient numbers in hospitals but there is an upward trend for long-term prescriptions for patients with chronic diseases. If the current situation were to be prolonged or become more serious, there may be a further decline in the number of new prescriptions and decline in prescriptions such as injections as part of hospital treatment due to restrictions on visits to health care facilities and the voluntary restraint on efforts to raise awareness of diseases, which may affect revenue. However, the negative impact of the pandemic on the parenteral nutrition market will be soon mitigated as different states/ countries allow medical clinics to reopen, services and once again being offered. IMPACT ON PRICE Due to the pandemic, the market is disturbed to a greater level. The several establishments have to remain shut while others scale down or put on hold expansion plans as they tried to survive the unprecedented crisis. Due to the impact of the coronavirus, many large pharmaceutical companies have placed new trials on hold and numerous small, mid-size, and large enterprises have suspended ongoing ones, thereby demonstrating the magnitude of the disruption. There have been uncertain past months due to the emergence of COVID-19. The sale of some company’s products experienced a downfall while others managed to stay afloat. For instance, · According to the annual report of Vifor Pharma Management Ltd., the sale of its products increased from USD 1794 million in 2019 to USD 1944.4 million in 2020 · According to the annual report of Otsuka Pharmaceutical Co. Ltd the nutraceuticals segment had a sale of USD 3,340.88 million with a business profit of 2.1 %. The total revenue in 2019 was USD 13,962.4 million which increased to USD 14,228.26 in 2020. As this lockdown has put manufacturers and distributors in worry as the key materials for the product, especially raw material supply are hindered; it will surely lead to change in prices up to an extent. IMPACT ON SUPPLY CHAIN As the world came to halt in the last few months due to the emergence of the pandemic, the supply chain couldn’t escape the impact. The government throughout the globe imposed total lockdown which led to supply chain disruptions. Consequently, the supply chain came to standstill due to the closure of borders. Even though the demand for parenteral nutrition remained untouched up to an extent, the availability was affected due to disruption in the supply chain, trade, and travel restrictions. Supply of raw material was also affected, due to which the product was affected. The outsourcing services which are providing warehousing, storage, and other services face challenges too. They are dependent on the logistic and transportation of chemical compound raw material from the outsourced service to the researchers' desk. However, with the sudden shut down globally with a ban in travel this process gets disrupted. Still, the companies managed to overcome the challenges and saw high growth. For instance, · According to the Annual report 2020 of Otsuka Pharmaceuticals Co. Ltd stated that concerning the procurement of raw materials, the purchasing channels overall are secure, although delays are occurring for some important items. Manufacturing had been temporarily suspended for some line items due to employees staying at home, but all manufacturing has been restored. The manufacturing operations are adequately staffed and proceeding smoothly. If the spread of COVID-19 were to be prolonged or become more serious causing stoppages in the procurement of raw materials, or if a cluster of infections or other similar cases occurred at a manufacturing plant, the supply of certain products may stop. However, the companies have been faced with substantial business and operational disruptions, which have included everything from mitigating the effects of reduced supply to managing disruptions to logistics suppliers, and indeed hurdle in meeting their contractual obligations to customers. The pandemic has forced the companies to rethink their supply chains and their stability and reliability for an uncertain future, including other externalities and government actions throughout the world, which have begun impacting supply chains, such as issues of sustainability. STRATEGIC INITIATIVES BY KEY PLAYERS As the reality of COVID-19 dawned upon the world, manufacturing and production unit of companies involved in parenteral nutrition key players formed strategies to mitigate with the limitations occurred due to the virus and keep their business running At the individual company level, companies are now more focused on operational resilience and accelerating initiatives that enable more agility, and transparency through the greater deployment of analytical tools and automation. Companies are considering re-evaluating their strategies, risk tolerance, and overall footprint. The market players have adopted various strategies including mergers, acquisitions, partnerships, and new product developments, among other strategies, to stay ahead of the competition and expand the market footprint. For instance, · In May 2021, Otsuka Pharmaceutical Co. Ltd announces that its affiliated company, Egypt Otsuka Pharmaceutical Co., S.A.E. (Egypt Otsuka), has agreed to jointly participate with a local pharmaceutical company Gypto Pharma for Trading and Pharmaceutical Manufacturing S.A.E. (Gypto) to establish a new company, Otsuka Gypto Pharmaceutical Egypt S.A.E. (Otsuka Gypto), which will sell ethical drugs such as IV solutions locally. However, to address the crisis all companies in this market are revisiting their financial trajectories and framing new strategies that will lead to bringing out solutions in the market resulting in increased business efficiency. CONCLUSION COVID-19 has impacted every sector with no exception global parenteral nutrition market has been affected the same. Different companies dealing in parenteral nutrition were finding out their way to deal with this pandemic situation. The government and companies around the globe are working together and have issued advice for those undergoing treatment for severe conditions during these unprecedented times during COVID-19 lockdown around the world. However, in the crisis call pharmaceuticals, key players, government bodies and healthcare organizations are working closely with healthcare professionals, customers, and patients for the betterment of public health. Thus, it is reasonable to assume that constraints on gathering and movement have disproportionally impacted people who use parenteral nutrition. However, healthcare industries and government bodies are exclusively concentrating on how they can make the effective and best contribution to control the spread of the virus and save lives. They are also ramping up the production of essential medicines to new levels and ensure that the speed doesn’t affect or destroy the quality of products.
COVID-19 Impact on Primary Pulmonary Hypertension (PPH) Treatment in Healthcare Industry | Data Bridge Market Research
COVID-19 Impact on Primary Pulmonary Hypertension (PPH) Treatment in Healthcare Industry Coronavirus (COVID-19) is an infectious disease caused by coronavirus 2 (SARS-CoV-2) and, thus, being a novel cause of sepsis. COVID-19 is a type of ARDS (acute respiratory distress syndrome) that originated in Wuhan, China. Due to its highly infectious nature, this disease is still spreading throughout the world. Although vaccines are now available in the market, due to various challenge (large scale manufacturing of novel vaccine, national vaccination protocol, availability of the vaccine, new variants of COVID-19, lesser quarantine strictness), it has not been able to slow down or stop the virus from spreading globally. In the treatment of COVID-19 patients with ARDS, Prostacyclin (a vasodilator), primarily known for treating pulmonary arterial hypertension (PAH), has shown promising results in many studies. Price Impact COVID-19 pandemic has a huge impact on every market globally. The cases of PAH are rising in the range of 100,000 to 200,000 per year. However, in the past few years, PAH has been increasing due to risk factors such as alcohol/tobacco consumption, HIV, sedentary lifestyle, smoking, and other idiopathic conditions. Increasing yearly demands and using Prostacyclin in the treatment of ARDS (COVID-19) patients has affected all major manufacturers of the drug. For instance: · Remodulin (Treprostinil) a drug sold by United Therapeutics Corporation. A standard single dose of 20 milliliters 1 mg/ml Remodulin cost has gone from USD 45 (2017) to USD 69.94 (2021) Prostacyclin manufacturing leaders (United Therapeutics Corporation, Janssen, GlaxoSmithKline, and Sandoz) worldwide face export restrictions that directly affect the product's market cost. An additional increase in demands due to COVID-19 treatment is anticipated to impact significantly the forecast period. Impact on Demand There is no specific and approved treatment to treat the Coronavirus disease (COVID-19), apart from prevention by social distancing and, now, using vaccination. However, inhalation of prostacyclin vasodilator has been shown to work synergistically with COVID-19 medication to recover ARDS patients on ventilators. Coupled with the uncapped spread of the virus. For instance: · Hamad Medical Corporation - Inhaled Iloprost (Phase II) for Suspected COVID-19 Respiratory Failure (ILOCOVID) Moreover, the geriatric population is more prone to PAH and associated diseases owing to reduced immune function. According to the National Council on Aging (NCOA), about 80% of the population aged 65 and above have at least one chronic condition: high cholesterol, diabetes, heart or kidney disease, or chronic obstructive pulmonary disease. Hence the market for global PPH treatment is speculated to boom in the forecasted period. Impact on Supply Chain COVID-19 restrictions and lockdown have affected the supply chain of all manufacturing firms globally. Prostacyclin (Europe and Asia-Pacific) primary manufacturer was under complete lockdown, causing manufacturers to shut down (temporarily) supply chains. For instance: · By the end of July 2020, nearly 90 countries had introduced export restrictions due to the COVID-19 pandemic, according to the WTO. Since January 2020, countries have taken more than 197 actions banning or limiting the export of certain products, according to Global Trade Alert · Overall, the U.S. exports to the world were down USD 8.47 billion when comparing the first two months of 2021 to the same period of 2019 To tackle these unique challenges, manufacturers are looking for innovative ideas and complete re-thinking of supply chains. Remote work has been another unique restraint put forth by mandatory lockdown, which requires a completely novel approach towards supply chain processes. Strategic Decisions for Manufacturers Sudden demand surge and lockdown caused temporary roadblocks. The shutdown of international transport and supply chains also requires immediate remedies. Manufacturers, to combat challenges presented by the COVID-19 pandemic, devised various ideas. New product launches, remote working environment, recommencing supply chain manufacturing with social distancing restrictions are some strategic decisions made by manufacturers For instance: · Beth Rhodes, Vice President, Global Supply Chain & Alliance Management at United Therapeutics said, “We are excited to bring to market the first subcutaneous pump designed specifically for PAH patients. Remunity is a small, discreet pump that delivers Remodulin in prefilled cassettes that are delivered directly to patients, offering significant improvements over current subcutaneous pumps” – CONCLUSION It is predicted that COVID-19 has a major impact on the primary pulmonary hypertension (PPH) treatment market. Increased PPH drugs (Remodulin, Flolan, Veletri, Ventavis) and strict trade policies globally have pushed manufacturers into considering new and compatible market strategies. However, increase the prevalence of pulmonary hypertension, robust drug pipeline, and changing lifestyle, drives the global primary pulmonary hypertension (PPH) treatment market. Moreover, technological advancement in treatment & diagnosis and growing genetic mutation-related disorders also boost up market growth. But adverse effects related to the treatment, unknown causes behind the disease, and difficulty in diagnosis of primary pulmonary hypertension (PPH) treatment may hamper the global Primary pulmonary hypertension (PPH) treatment market.