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Carcinoid Syndrome Drug Market Size, Share, Growth, Potential Revenue and Key Drivers Analysis Research Report by 2026

Market Analysis: Global Carcinoid Syndrome Drug Market
Carcinoid syndrome drug market is rising gradually with a healthy CAGR in the forecast period of 2019-2026. Government policies and initiatives to offer a fund to many research institute and pharmaceuticals companies for developing novel therapy and emergence of drugs used in the treatment of neuroendocrine tumors are the key factors for market growth.
Market Definition: Global Carcinoid Syndrome Drug Market
Carcinoid Syndrome is also known as carcinoid cancer or neuroendocrine tumor carcinoid type is ultra-rare endocrinology disorder develops in patients with carcinoid tumors and is characterized by cutaneous flushing, diarrhea and abdominal cramps. The carcinoid syndrome results from the production of vasoactive substances (including serotonin, bradykinin, histamine, prostaglandins, polypeptide hormones) secreted by the neuroendocrine tumorous cells.
According to the statistics published in the National Organization for Rare Disorders, Inc, it was identified up to 27new cases in every one million people diagnosed with carcinoid tumors in the United States. The certain toxin and change in hormonal chemical substances have largely contributed to the rising prevalence of carcinoid syndrome and accelerating demand of novel therapies are the key factors to the market growth.
Market Drivers
Rising awareness about treatment and technological advancement is driving the growth of market
Adoption of unhealthy life style, irregular eating habits and lack of physical exercise also drives the market growth
Rapid adoption of newer formulations and novel dosage forms boosts the market growth
The emergence of drugs used in the treatment of risk associated with neuroendocrine tumor can also drive the growth of this market

Market Restraints
High cost involved in treatment and diagnosis restricts the market growth
Lack of expertise and inadequate knowledge about carcinoid syndrome in some developing countries also hinders the market growth
Scientific and major technical challenges for production of disease specific novel therapies acts as a restraint for this market

Segmentation: Global Carcinoid Syndrome Drug Market
By Organ Affected
Small Intestine
Lungs
Rectum
Appendix
Colon
Stomach
Pancreas
Liver
Others

By Therapy Type
Chemotherapy
Biological Therapy
Radiotherapy

By Treatment
Medication
Surgery

By Drug
Octreotide
Telotristat Etiprate
Lanreotide
Others

By Route of Administration
Oral
Injectable

By Distribution Channel
Online Pharmacy
Direct Tenders
Retailers
Others

By End-Users
Hospitals
Homecare
Specialty Clinics
Others

By Geography
North America
U.S.
Canada
Mexico

South America
Brazil
Rest of South America

Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Turkey
Belgium
Netherlands
Switzerland
Rest of Europe

Asia-Pacific
Japan
China
South Korea
India
Australia
Singapore
Thailand
Malaysia
Indonesia
Philippines
Rest of Asia Pacific

Middle East & Africa
South Africa
Rest of Middle East & Africa


Key Developments in the Market:
In February 2018, Ipsen Biopharmaceuticals, Inc received Health Canada approval in Canada for Somatuline Autogel (lanreotide injection) for the treatment of carcinoid syndrome in adult patients with neuroendocrine tumours (NETs). This new indication of Somatuline Autogel significantly changes the treatment landscape for patients
In February 2017, LEXICON PHARMACEUTICALS, INC received the FDA approval for Xermelo (telotristat ethyl), an oral serotonin inhibitor for the treatment of carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in cancer patients with metastatic neuroendocrine tumor. This approval of Xermelo helps patients suffering from carcinoid syndrome diarrhea throughout the United States
Competitive Analysis:
Global carcinoid syndrome drug market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of Global Farber's Disease Drug market for global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.
Key Market Players:
Few of the major competitors currently working in the global carcinoid syndrome drug market are Novartis AG, Teva Pharmaceutical Industries Ltd., Mylan N.V., LEXICON PHARMACEUTICALS, INC, Ipsen Biopharmaceuticals, Inc, Sirtex SIR-Spheres Pty Ltd, BTG International Ltd, WOCKHARDT, Sun Pharmaceutical Industries Ltd, Amgen Inc, Entrinsic Health Solutions, Inc., Camurus AB, Endo Pharmaceuticals Incand many others
Primary Respondents
Demand Side: Doctors, Surgeons, Medical Consultants, Nurses, Hospital Buyers, Group Purchasing Organizations, Associations, Insurers, Medical Payers, Healthcare Authorities, Universities, Technological Writers, Scientists, Promoters, and Investors among others.
Supply Side: Product Managers, Marketing Managers, C-Level Executives, Distributors, Market Intelligence, and Regulatory Affairs Managers among others.
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QUESTION 480 Note: The question is included in a number of questions that depicts the identical set-up. However, every question has a distinctive result. Establish if the solution satisfies the requirements. Your company's Azure subscription includes two Azure networks named VirtualNetworkA and VirtualNetworkB. VirtualNetworkA includes a VPN gateway that is configured to make use of static routing. Also, a site-to-site VPN connection exists between your company's on-premises network and VirtualNetworkA. You have configured a point-to-site VPN connection to VirtualNetworkA from a workstation running Windows 10. After configuring virtual network peering between VirtualNetworkA and VirtualNetworkB, you confirm that you are able to access VirtualNetworkB from the company's on-premises network. However, you find that you cannot establish a connection to VirtualNetworkB from the Windows 10 workstation. 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As a result, these questions will not appear in the review screen. You have an Azure virtual machine named VM1 that runs Windows Server 2016. You need to create an alert in Azure when more than two error events are logged to the System event log on VM1 within an hour. Solution: You create an Azure Log Analytics workspace and configure the Agent configuration settings. You install the Microsoft Monitoring Agent on VM1. You create an alert in Azure Monitor and specify the Log Analytics workspace as the source. Does this meet the goal? A.Yes B.No Answer: A QUESTION 497 Note: This question is part of a series of questions that present the same scenario. Each question in the series contains a unique solution that might meet the stated goals. Some question sets might have more than one correct solution, while others might not have a correct solution. After you answer a question in this section, you will NOT be able to return to it. As a result, these questions will not appear in the review screen. You manage a virtual network named VNet1 that is hosted in the West US Azure region. VNet1 hosts two virtual machines named VM1 and VM2 that run Windows Server. You need to inspect all the network traffic from VM1 to VM2 for a period of three hours. Solution: From Azure Monitor, you create a metric on Network In and Network Out. Does this meet the goal? A.Yes B.No Answer: B QUESTION 498 Note: This question is part of a series of questions that present the same scenario. Each question in the series contains a unique solution that might meet the stated goals. Some question sets might have more than one correct solution, while others might not have a correct solution. After you answer a question in this section, you will NOT be able to return to it. As a result, these questions will not appear in the review screen. You have an app named App1 that is installed on two Azure virtual machines named VM1 and VM2. 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After you answer a question in this section, you will NOT be able to return to it. As a result, these questions will not appear in the review screen. You have a computer named Computer1 that has a point-to-site VPN connection to an Azure virtual network named VNet1. The point-to-site connection uses a self-signed certificate. From Azure, you download and install the VPN client configuration package on a computer named Computer2. You need to ensure that you can establish a point-to-site VPN connection to VNet1 from Computer2. Solution: On Computer2, you set the Startup type for the IPSec Policy Agent service to Automatic. Does this meet the goal? A.Yes B.No Answer: B 2021 Latest Braindump2go AZ-104 PDF and AZ-104 VCE Dumps Free Share: https://drive.google.com/drive/folders/1UgWYSJj0uEU0eN4Uz8jnKDmXdqJJkSzZ?usp=sharing
Điểm danh các loại giá kệ sắt siêu thị phổ biến trên thị trường
Dạo một vòng quanh thị trường giá kệ có thể thấy sự xuất hiện của rất nhiều đơn vị cung cấp với chất lượng và giá thành khác nhau. Tùy thuộc vào nhu cầu sử dụng, mặt hàng trưng bày cũng như chi phí đầu tư mà bạn có thể lựa chọn mẫu kệ sắt có kiểu dáng, kết cấu phù hợp. 3 mẫu kệ đang được sử dụng nhiều nhất hiện nay Kệ siêu thị lưng lưới Đây là mẫu kệ được sử dụng nhiều nhất trong các siêu thị, cửa hàng, hệ thống mua bán hiện nay. Với phần lưng kệ là tấm lưới ô vuông giúp việc bày hàng trở nên thông thoáng, dễ quan sát và thuận tiện cho việc tìm kiếm hàng hóa của người mua. Kệ siêu thị lưng lưới được làm từ sắt sơn tĩnh điện, có khả năng chịu lực đến 120kg/ mâm tầng dàn đều. Có thể điều chỉnh khoảng cách mâm tầng, di chuyển theo nhu cầu một cách đễ dàng. Kệ siêu thị lưng tôn đục lỗ Xét về tính thẩm mỹ và độ bền chắc thì kệ tôn đục lỗ được xếp đầu tiên trong danh sách các loại kệ bày hàng siêu thị, cửa hàng tạp hóa. Mẫu kệ này có khả năng chịu tải lên đến 150kg/ mâm tầng dàn đều phù hợp với nhiều nhu cầu sử dụng như để trưng bày các mặt hàng mẹ và bé, đồ tạp hóa, đồ gia dụng, hoa quả tươi, nước uống, gia vị,… Kệ siêu thị lưng tôn liền Đây là mẫu kệ có thiết kế mặt lưng là tấm tôn liền nguyên khối, kết cấu chắc chắn có khả năng chịu lực tốt nhất trong các mẫu kệ sắt siêu thị trên thị trường. Kệ tôn liền được dùng để trưng bày các sản phẩm hàng hóa có trọng lượng cao như Đồ gia dụng, hàng điện tử, điện lạnh, sữa,… Kệ có độ bền và tuổi thọ từ 15 – 20 năm. Đương nhiên mẫu kệ này cũng có giá thành tương đối cao. Địa chỉ mua giá kệ sắt bày hàng siêu thị giá tốt Như đã nói ở trên, hiện nay có rất nhiều đơn vị cung cấp sản phẩm kệ siêu thị trên thị trường với chất lượng và giá thành khác nhau. Co đơn vị bán với giá khá rẻ nhưng cũng có đơn vị bán kệ với giá cao. Tuy nhiên cái gì cũng có mặt tốt và không tốt của nó. Giá rẻ thì chất lượng sẽ không được đảm bảo, mà chất lượng tốt, bảo dành dài thì giá sẽ tương đương. Do đó, tùy thuộc vào mục đích sử dụng, chi phí đầu tư mà bạn có thể chọn mua kệ ở những đơn vị uy tín. Tốt nhất nên mua kệ tại những đơn sản xuất và cung cấp trực tiếp, không nên mua qua trung gian. Vì những nơi trực tiếp sản xuất và cung cấp giá kệ đến tay khách hàng sẽ có giá bán hợp lý đi kèm với chế độ bảo hành chuyên nghiệp hơn. Giá kệ Thăng Long hiện là nhà máy sản xuất kệ siêu thị uy tín trên thị trường. Với hơn 10 năm kinh nghiệm, Thăng Long được nhiều đơn vị, khách hàng tin tưởng và lựa chọn. Kệ do Thăng Long được sản xuất sản xuất trên dây chuyền công nghệ hiện đại, đảm bảo về chất lượng, độ bền tốt và tuổi thọ lâu bền. Hiện nay Thăng Long đã và đang cung cấp đa dạng nhiều dòng kệ sắt bày hàng siêu thị với đủ mọi kích thước, kiểu dáng và mức giá cho khách hàng lựa chọn. Các dòng kệ đều được bảo hành 5 năm, hỗ trợ vận chuyển và lắp đặt miễn phí. Mọi thông tin vui lòng liên hệ hotline: Thông tin liên hệ mua hàng: CÔNG TY CP ĐẦU TƯ VÀ TRANG THIẾT BỊ THĂNG LONG Hotline/zalo tư vấn bán hàng: 0919.467.868 - 0964.196.611 Website: Sieuthigiake.com Khu vực Miền Bắc: Số 1, Ngõ 58 Trần Bình - Mai Dịch - Cầu Giấy - Hà Nội Khu vực Miền Trung: Ngách 143 Điện Biên Phủ, Thanh Khê, Đà Nẵng Khu vực Miền Nam: 60/6C Bà Điểm 5, ấp Tây Lân, Xã Bà Điểm, Huyện Hóc Môn, TP. Hồ Chí Minh.
The Truth About Hormonal Acne And How To Control It
Indian women's hormonal environments have changed dramatically as a result of increased stress and poor lifestyle choices. When it comes to polycystic ovaries, the condition is a hereditary one that can be passed down from mother to daughter. A hormonal imbalance known as PCOS or PCOD has become more common among women and young girls as obesity has become more common. Despite the fact that PCOD is a gynaecological condition marked by irregular menstruation, it is most commonly diagnosed when patients visit a dermatologist for persistent acne, hirsutism, or hair loss. So, as a dermatologist, when do I suspect PCOS or hormonal acne? Suspicion usually arises during a consultation when one or more of the following factors are present: * Inflammatory acne exacerbated by premenstrual hormones. * Acne predominantly on the lower half of their face, the jawline, and upper neck. * Hair loss and/or hirsutism are also present. * Intense acne brought on by menstrual irregularities or PCOS. Acne that does not respond to conventional acne treatments like topicals, antibiotics, or chemical peels is likely hormonal acne if none of the above factors can be ruled out. Is it possible for a dermatologist to tell whether or not acne is caused by hormones? It's a little complicated here. It is suggested that you undergo a series of blood tests. A clear hormonal imbalance may be discovered, or the results may be within normal ranges. While normal test results don't exclude PCOD as a possibility, the ratios of different investigations are taken into account when making this determination. The clinical diagnosis may be correct even if laboratory tests are negative! When do you have your hormonal tests? The use of anti-androgen medications is usually not recommended during the first consultation if the clinical diagnosis of hormonal acne is clear. Conventional acne treatment is started and response is tracked. Investigations may not be required if the response is adequate. After 6-8 weeks of treatment, if the patient does not improve, hormonal testing may be recommended. Is it necessary to treat hormonal acne and PCOS acne with hormones in all cases? No, that's not always the case. Patients who need a quick response and are open to hormonal treatment begin taking the medication at the beginning of their acne treatment. Patients who don't want to take hormones are prescribed antibiotics/retinoids, including topical and oral forms, as well as chemical peels. To effectively control mild to moderate hormonal acne, I typically use advanced chemical peels such as Agera, Obagi Blue peel Radiance, and Azelan. The patient is encouraged to start taking medication if his or her response does not improve after 3-4 sessions. Patients who do not see improvement after 6-8 sessions are re-explained that oral anti-androgen medication is needed to control acne. Acne is a completely curable dermatology lifestyle disorder. Non-hormonal acne takes 1-2 months to treat, while hormonal acne takes 3-6 months. Hormonal acne requires a more stringent maintenance plan as well. This may comprise of customised skin care as well as ocassional chemical peels. You should find yourself a dependable dermatologist and start a long-term relationship.
[September-2021]Braindump2go New MD-100 PDF and VCE Dumps Free Share(Q281-Q294)
QUESTION 281 Your network contains an Active Directory domain. All users have been issued with new computers that run Windows 10 Enterprise. All users have Microsoft 365 E3 licenses. A user named Mia Hamm has an Active Directory user account named MHamm and a computer named Computer1. Mia Hamm reports that Computer1 is not activated. You need to ensure that Mia Hamm can activate Computer1. What should you do? A.Assign a Windows 10 Enterprise license to MHamm, and then activate Computer1. B.From the Microsoft Deployment Toolkit (MDT), redeploy Computer1. C.From System Properties on Computer1, enter a Volume License Key, and then activate Computer1. D.Instruct Mia Hamm to perform a local AutoPilot Reset on Computer1, and then activate Computer1. Answer: D QUESTION 282 Your network contains an Active Directory domain that is synced to a Microsoft Azure Active Directory (Azure AD) tenant. The company plans to purchase computers preinstalled with Windows 10 Pro for all users. The company the following requirements: - The new computers must be upgraded to Windows 10 Enterprise automatically. - The new computers must be joined to Azure AD automatically when the user starts the new computers for the first time. - The users must not be required to accept the End User License Agreement (EULA). You need to deploy the new computers. What should you do? A.Make use of the wipe and load refresh deployment method. B.Perform in-place upgrade on the new computers. C.Provide provisioning packages for the new computers. D.Make use of Windows Autopilot. Answer: D QUESTION 283 Your company is not connected to the internet. The company purchases several new computers with Windows 10 Pro for its users. None of the new computers are activated. You need to activate the computers without connecting the network to the Internet. What should you do? A.Make use of the Volume Activation Management Tool (VAMT). B.Make use of the Key Management Service (KMS). C.Make use of the Windows Process Activation Service. D.Run the Get-WmiObject -query cmdlet. Answer: B QUESTION 284 Your network contains an Active Directory domain. All users have been issued with computers that run Windows 8.1. A user named Mia Hamm has a computer named Computer1. You upgrade Computer1 to Windows 10 by performing a clean installation of Windows 10 without formatting the drives. You need to migrate the settings for Mia Hamm from Windows 8.1 to Windows 10. Which two actions should you perform? NOTE: Each correct selection is worth one point. A.Run scanstate.exe and specify the C:\Users folder B.Run loadstate.exe and specify the C:\Windows.old folder C.Run usmultils.exe and specify the C:\Users folder D.Run scanstate.exe and specify the C:\Windows.old folder E.Run loadstate.exe and specify the C:\Users folder F.Run usmultils.exe and specify the C:\Windows.old folder Answer: DE QUESTION 285 You have a computer named Computer1 that runs Windows 10. You deploy an application named Application1 to Computer1. You need to assign credentials to Application1. You need to meet the following requirements: Ensure that the credentials for Application1 cannot be used by any user to log on to Computer1. Ensure that the principle of least privilege is maintained. What should you do? A.Configure Application1 to sign in as the Local System account and select the Allow service to interact with desktop check box. B.Create a user account for Application1 and assign that user account the Deny log on locally user right C.Create a user account for Application1 and assign that user account the Deny log on as a service user right D.Configure Application1 to sign in as the Local Service account and select the Allow service to interact with desktop check box. Answer: B QUESTION 286 Your network contains an Active Directory domain that is synced to a Microsoft Azure Active Directory (Azure AD) tenant. All users have been issued with laptop computers as well as desktop computers that run Windows 10 Enterprise. All users have Microsoft 365 E3 licenses. A user named Mia Hamm informs you that she must perform a BitLocker recovery on her laptop but she does not have her BitLocker recovery key. You need to ensure that Mia Hamm can perform a BitLocker recovery on her laptop. What should you do? A.Instruct Mia Hamm to log on to her desktop computer and run the repair-bde.exe command. B.Instruct Mia Hamm to use the BitLocker Recovery Password Viewer to view the computer object of the laptop. C.Instruct Mia Hamm to log on to her desktop computer and go to https:// account.activedirectory.windowsazure.com and view the user account profile. D.Instruct Mia Hamm to run the Enable-BitLocker cmdlet on her laptop. Answer: C QUESTION 287 Your company has an on-premises network that contains an Active Directory domain. The domain is synced to Microsoft Azure Active Directory (Azure AD). All computers in the domain run Windows 10 Enterprise. You have a computer named Computer1 that has a folder named Folder1. You must provide users in group named Group1 with the ability to view the list of files in Folder1. Your solution must ensure that the principle of least privilege is maintained. What should you do? A.Assign the Full control permissions for the Folder1 folder to Group1. B.Assign the Read permissions for the Folder1 folder to Group1. C.Assign the List folder permissions for the Folder1 folder to Group1. D.Assign the Take ownership permissions for the Folder1 folder to Group1. Answer: C QUESTION 288 You have a computer named Computer1 that runs Windows 10. Computer1 has a folder named C:\Folder1. You need to meet the following requirements: - Log users that access C:\Folder1. - Log users that modify and delete files in C:\Folder1. Which two actions should you perform? A.From the properties of C:\Folder1, configure the Auditing settings. B.From the properties of C:\Folder1, select the Encryption contents to secure data option. C.From the Audit Policy in the local Group Policy, configure Audit directory service access. D.From the Audit Policy in the local Group Policy, you configure Audit object access. E.From the Audit Policy in the local Group Policy, you configure Audit system events. Answer: AD QUESTION 289 Your company has a computer named Computer1 that runs Windows 10. Computer1 is used to provide guests with access to the Internet. Computer1 is a member of a workgroup. You want to configure Computer1 to use a user account sign in automatically when the the computer is started. The user must not be prompted for a user name and password. What should you do? A.Configure Group Policy preferences. B.Run the BCDBoot command. C.Edit the Registry. D.Run the MSConfig command. Answer: C QUESTION 290 Your network contains an Active Directory domain. The domain contains computers that run Windows 10. You must ensure that Windows BitLocker Drive Encryption is enabled on all client computers, even though a Trusted Platform Module (TPM) chip is installed in only some of them. You need to accomplish this goal by using one Group Policy object (GPO). What should you do? A.Enable the Allow enhanced PINs for startup policy setting, and select the Allow BitLocker without a compatible TPM check box. B.Enable the Enable use of BitLocker authentication requiring preboot keyboard input on slates policy setting, and select the Allow BitLocker without a compatible TPM check box. C.Enable the Require additional authentication at startup policy setting, and select the Allow BitLocker without a compatible TPM check box. D.Enable the Control use of BitLocker on removable drives policy setting, and select the Allow BitLocker without a compatible TPM check box. Answer: C QUESTION 291 You have a computer named Computer1. Computer1 runs Windows 10 Pro. Computer1 is experiencing connectivity issues. You need to view the IP addresses of any remote computer that Computer1 has an active TCP connection to. Should you do? A.In Windows Administrative Tools, open Performance Monitor. B.In the Control Panel, open Network and Internet. Then select Network and Sharing Center. C.In Windows Administrative Tools, open Resource Monitor. D.In the Setting app, open Update and Security. Then open Windows Security and select Firewall and Network protection. Answer: C QUESTION 292 You have a computer named Computer1. Computer1 runs Windows 10 Pro. You attempt to start Computer1 but you receive the following error message: Bootmgr is missing. You need to be able to start Computer1. What should you do? A.Start the computer in recovery mode and run the bootrec /rebuildbcd command. B.Start the computer in recovery mode and run the diskpart /repair command. C.Start the computer in recovery mode and run the bcdboot /s command. D.Start the computer in recovery mode and run the bootcfg /debug command. Answer: A QUESTION 293 Your company has several mobile devices that run Windows 10. You need configure the mobile devices to meet the following requirements: Windows updates may only be download when mobile devices are connect to Wi-Fi. Access to email and the Internet must be possible at all times. What should you do? A.Open the Setting app and select Update & Security. Then select and configure Change active hours. B.Open the Setting app and select Network & Internet. Then select Change connection properties, and set the Metered connection option for cellular network connections to On. C.Open the Setting app and select Network & Internet. Then select Data Usage and set a data limit. D.Open the Setting app and select Update & Security. Then select and configure Delivery Optimization. Answer: B QUESTION 294 Note: This question is part of a series of questions that present the same scenario. Each question in the series contains a unique solution that might meet the stated goals. Some question sets might have more than one correct solution, while others might not have a correct solution. After you answer a question in this section, you will NOT be able to return to it. As a result, these questions will not appear in the review screen. Your company has an on-premises network that contains an Active Directory domain. The domain is synced to Microsoft Azure Active Directory (Azure AD). All computers in the domain run Windows 10 Enterprise. You have a computer named Computer1 that has a folder named C:\Folder1. You want to use File History to protect C:\Folder1. Solution: You enable File History on Computer1. You then enable archiving for Folder1. Does this meet the goal? A.Yes B.No Answer: B 2021 Latest Braindump2go MD-100 PDF and MD-100 VCE Dumps Free Share: https://drive.google.com/drive/folders/1JUVP5MWzD2NVdlAoSATpQirlejY0T0r_?usp=sharing
What Causes Strawberry Legs And How To Get Rid Of It?
Summer is arrived, which means you're most likely showing a little more skin. As our gams finally receive their due, pants become shorts, maxi dresses become minis, and skirts become minis. Short hemlines, on the other hand, may be undesirable to those whose legs are spotted, bumpy, or spotty. Let's learn more about how a dermatologist treats and prevents skin diseases known as "strawberry legs." What Are 'Strawberry Legs,' Exactly? Strawberry legs refers to a dotty appearance of the legs, mainly around the hair follicles. The dots depict the buildup of common skin elements in and around the hair and oil glands. Keratin is a type of protein that is found in (the main protein in the skin) * Melanin is a pigment found in the skin (the source of pigment) * Sebum is a type of oil that is produced by (natural oil of the skin) * Bacteria are microorganisms (often, normal skin flora) The name "strawberry legs" refers to the dark pores and dots or red pimples that emerge on the lower thighs and resemble strawberry seeds. Strawberry legs are not hazardous in terms of health, but they are ugly. Strawberry Legs: What Causes Them and How to Treat Them While the appearance of strawberry legs is typically the same no matter what caused it, there are a number of causes. Knowing what's causing your dotted gams can allow you to address the appropriate ailment. The four most prevalent causes of strawberry legs, as well as how to cure them, are listed below. 1. Clogged Pores Clogged pores on your legs are just as common as clogged pores on your face. Because of heredity and thicker body hair, some people have larger pores, and while the pores themselves aren't inherently irritating, they can become problematic when they become blocked with germs, dead skin, and sebum. When clogged pores on the legs are exposed to air, the debris dries up and darkens, in the same way that a blackhead on the face does. Treat with: Chemical and physical exfoliation. Exfoliation, which is part of your facial skincare routine, can be used to cure congested pores on the legs or anyplace else on the body. My personal favourite for my patients is chemical exfoliation, which uses chemicals such as acids and retinols to stimulate skin cell turnover and clear pores. This eliminates keratin, oils, and other skin detritus gently, opening up pores and follicles and preventing secondary bacterial buildup. Acne and folliculitis bacteria grow in oil-clogged hair follicles, so eliminating that build-up is critical. Look for a body wash or moisturiser that contains alpha-hydroxy acids (AHAs) and beta-hydroxy acids (BHAs), notably glycolic acid and salicylic acid, to exfoliate dead skin cells and other debris that create clogged pores. These acids gently exfoliate the skin by minimising the'stickiness' of dead or dying skin cells. This helps to open up the pores while also giving the skin a great textural shift and radiance. 2. Folliculitis Folliculitis is a skin disorder that causes inflamed or infected hair follicles. The most common sign is little red pimples around the hair follicles. Hair loss or scarring in the affected area may occur in extreme situations. The majority of instances, however, are small and normally resolve within a few days. It's crucial to note that folliculitis is a catch-all term for inflammation of the hair follicle. This can be contagious due to microorganisms like staphylococcus or sterile due to oil buildup or shaving stress. Treat with: Antibiotics, both oral and topical. Folliculitis is a "tricky condition" to treat, which is why you should consult a dermatologist before trying any at-home therapies. Folliculitis can be sterile, with red, pus-filled pimples forming as a result of causes like clogged pores and shaving. They can, however, indicate a superficial skin infection caused by bacteria or yeast such as staph and pityrosporum. While the former can be treated with over-the-counter medications, the latter may require prescriptions for antibiotic creams or even pills to resolve. A simple swab can be used by a dermatologist to assess whether or not organisms should be targeted. If there are, it might save you a lot of time and effort in developing successful at-home habits. Treat with: Antibacterial skincare. At-home treatments range from lifestyle changes to skincare. To begin, change out of your sweaty training clothes and shower as quickly as possible. In the shower, lather up with antibacterial soap. Treat with: Laser hair removal treatment. You should also reconsider your shaving routine. Use a soothing shave cream in addition to converting from a multi-bladed razor to a disposable razor. In return for less rough skin, the closest shave is compromised. The risk of folliculitis is inversely associated to a close shave. He also suggests shaving with the grain rather than against it every two to three shaves. If you're prone to razor bumps, laser hair removal with a dermatologist will save you a lot of time and aggravation in the long run. 3. Keratosis Pilaris Keratosis pilaris (KP), popularly known as "chicken skin," is a skin disorder characterised by the appearance of small bumps on the skin. Keratosis pilaris most usually affects the upper outer arms, however it can also affect the thighs. Keratin accumulation in the hair follicles causes this. Treat with: Chemical exfoliation. Chemical exfoliants, like clogged pores, are frequently efficient in the treatment of keratosis pilaris, but prescription-strength treatments may also be beneficial. Exfoliative acids are my first line of defence against keratosis pilaris. If those don't work, a prescription-grade retinoid may be an option, but only after consulting with a dermatologist. While keratosis pilaris is usually a year-round condition, flare-ups are more likely in the winter when the skin is drier. Additionally, swimmers may aggravate the illness due to the dehydrating effects of chlorine and other pool chemicals. 4. Dry Skin Dry skin, as previously indicated, contributes to a number of skin diseases, including strawberry legs. Dehydrated skin is more susceptible to irritation, especially during shaving. Dry skin on the lower legs is more prone to razor burn, keratosis pilaris, folliculitis, and plugged pores, all of which can result in a spotty appearance. Treat with: Creams and moisturisers. For severely dry skin, a daily moisturising body lotion containing ammonium lactate is an excellent place to start, especially if it is scaly. Ichthyosis, or dry, scaly, or thickened skin, may not usually respond to regular creams and moisturisers, thus a dual-purpose formulation may be necessary. Because there is a thicker layer of dead skin on the surface, moisturising alone isn't always adequate. Exfoliating lotions gradually remove that layer, allowing richer moisturisers to penetrate deeper into the healthier layers beneath. In conclusion Strawberry legs are a catch-all name for a range of skin disorders, but there are a few things you can do at home and at the workplace to cure and prevent a bumpy or spotty appearance. Consult a board-certified dermatologist before attempting to treat yourself to ensure you understand the underlying cause of your illness.
Why Your Business Needs Online Timesheets
A business gets a better vision of the future when it knows how its employees are performing. From a business point of view, productivity and tracking time allow you to improve the team’s performance, maximize resources, and gain accurate knowledge of how hours are being spent.  What is Online Timesheet? The timesheet is a data sheet that employers use to track the time of employees for a certain period of time. It is basically a record of time spent by the employees on a particular task, client, or project. There have been different ways to record the timesheet, like, paper, spreadsheet software, excel, and nowadays online timesheets software.  Why should Businesses use Timesheets? For any business to rise and shine, there should be effective work performed for effective results. Thus, a business owner wants its employees to utilize their work duration in a productive manner. Having a fleet of employees, it becomes quite difficult to understand each employee’s efficiency to finish their task.  Therefore, it turned out necessary to keep track of the employee’s dedication to complete the project. Here Timesheet comes into play. It will help to determine each employee’s work status. Accordingly, you can motivate the employee who is working slow.  This will help to meet deadlines and maintain the budget also. Advantages of Timesheets - Reduce Time Wastage Accurate billing Automates Billing Project Management Saves Company’s expenditure How do different business sectors use Timesheets? Various types of industries are using Online Timesheets in different terms. Let’s check out how: Law Firm – The law firm sector keeps a record of their client’s dealing hours and maintains a list of services they provide. Here, the timesheet assists in tracking the bill according to the client servicing hours. Freelancers – Many freelancers charge per hour with the clients. Thus, maintaining the time record is very necessary. To do this, freelancers use the Timesheet online calculator that helps to record the time precisely. This helps to keep transparency between you and the client. Accountants – The accountant’s profit depends on how the workers of the company spend time to complete the client’s project: the more billability, the more profit. Thus, to set a record of the time and bills, the Timesheet is required. But, correct software should be chosen for the accountants that can help in employee tracking and maintaining the online timesheet. One recommended software is WorkStatus, which includes an all-in-one feature.  Final Words With the growth in technology, time has become a vital part of businesses, and simultaneously a timesheet has been chosen by different industries, to know each hour’s production. An Online Timesheets Software like WorkStatus will help you provide an auto-update about the time schedules of the employees. This will help your business to drive to success. So, say bye-bye to paper timesheets and choose the software that will give accurate time notes, and your data will be safe and secured. Source : Why Your Business Needs Online Timesheets | Benefits & User Manual
How COVID-19 Impacted on Oral Care in Healthcare Industry ?
COVID-19 Impact on Oral Care in Healthcare Industry OVERVIEW The COVID-19 pandemic has posed a complex challenge in front of several healthcare companies and proved to be an unprecedented global health threat. This global pandemic has emerged in December 2019 which has been proved as a global pandemic by WHO in March 2020. With the development and introduction of novel coronavirus vaccine, COVID-19 cases have been declined but with the development of mutant coronavirus strain, the overall COVID-19 cases have been surged and are increasing at a rapid rate in India, and the U.K, and other European countries. The most common symptoms associated with this include cough, fever, diarrhea, sore throat, and loss of smell or taste. Patients affected with COVID-19 are at increased risk of developing hepatic manifestations and also experiences damage to liver tissues. COVID-19 has led to the closure and reduced hours of dental practices except for emergency and urgent services, limiting routine care and prevention. Dental care includes aerosol-generating procedures that can increase viral transmission. The pandemic offers an opportunity for the dental profession to shift more toward non-aerosolizing, prevention-centric approaches to care and away from surgical interventions. Direct effects of COVID-19 on oral health include ageusia (an official symptom of COVID-19) and case reports of vesiculobullous lesions and necrotizing periodontal disease. oral care product has a wide portfolio such as breath Fresheners, Mouth Wash, Dental Floss, among other products. The Article here shows the impact of COVID-19 on the oral care market. IMPACT ON PRICE As the mouth is an important place for bacterial colonization due to which it is necessary to use the product for oral hygiene. With the sudden increase in COVID-19 cases, people's concerns for better health had also increased and the link between oral health and COVID-19 infection also expand the health to oral. As India relies on China for 70% of API’s intermediates and bulk ingredients, COVID -19 is expected to hike the price of the ingredient used for an oral care product For instance, · In the year 2021, As Proctor & Gamble announced the third-quarter result in which the net sales increase by 5 %, and also mentioned that they are planning for a price hike in certain product divisions. This step is taken seeking to recover the revenue loss during COVID-19. · According to GlaxoSmithKline plc, the cost of dental consultation and treatment was cited as the concerning factor IMPACT ON DEMAND The coronavirus has affected the various regions of the world and caused the widespread closure of companies and local manufacturing plants. This lockdown and isolation have adversely impacted global economic activity. As studies around the world have shown the improving oral hygiene is expected to increase the chance of generating demand for the product. THE IMPACT OF COVID-19 INFECTION ON ORAL CARE The rising awareness of oral hygiene COVID-19 has increased the demand for a product requires for oral care as the increasing studies for SARS-COV-2 indicated that proper oral hygiene has been reported to decrease the chances of infection which increases the demand for mouth wash, oral povidone solution, novel gargle solution. · However, due to restrictions and aims to reduce COVID-19 transmission, 30% of respondents had visited a dentist less frequently during the pandemic The second cause of increasing demand for oral care products is that approximately 90% of the product used in oral care are over the counter which can be added as the plus point in maintaining the demand for oral care products. The market players in oral care are also focused on the research to bring novel products to interstate commerce. For instance, · Microbac Laboratories, an independent and internationally accredited testing facility worked on behalf of Unilever Research Laboratories, has found that rinsing with mouthwash containing CPC Technology for 30 seconds is effective in reducing the viral load of SARS-CoV-2, the virus that causes Covid-19, by 99.9%. This type of research surge the demand for the oral product · Colgate-Palmolive President mentioned in an interview that they have seen elevated demand for oral care related to viruses, which also boosted the innovative growth related to a premium product This suggests that the increasing prevalence of COVID-19 poses precautionary measures due to which the global population started to take concern for their health hence enhance the demand for oral care. This thus signifies that COVID-19 is accelerating the demand of the oral care market. IMPACT ON SUPPLY The COVID 19 pandemic has affected and badly disrupted the global drug supply chain due to the continuous shut down of manufacturing facilities and restrictions imposed by the government over import and export activities. As per global sources, it was found that the beauty care business is still facing a crisis due to COVID-19. However, oral care market players are in a strong position. The two main leaders Colgate-Palmolive and Johnson and Johnson had seen a lift in sales in Q1 2020. Colgate-Palmoliva has net sales of USD 415 million for Q3 2020, up by 5.5% from the previous year. The surge of demand for oral care increased during COVID-19 however, the global restriction, and state-wise travel restriction has caused challenges for the market player. Moreover, there are many local players also in the oral care market that continued to fulfill the demand in case of any disruption. Oral care is categorized under essential need products which leads to the easy flow of these products. The main challenges during the pandemic is the supply of API’s and Ingredient or excipient used in toothpaste, as China holds the major share in API’s and other chemicals used in oral care and global restriction has somehow affected the supply chain for these products too. This, thus signifies that due to continuous lockdown and several restrictions by government authorities the companies and patients are facing disruption of the supply chain for oral care. However, oral care is categorized under essential care which lowers the effect of supply chain disruption during COVID-19. STRATEGIC DECISIONS OF MANUFACTURERS Collaboration, agreements, strategic initiatives, product launches by market players such as Colgate Palmolive, Hindustan Unilever among others in the oral care market will help them to expand their product portfolio and to provide appropriate products to the consumer. This in turn will lead to increased product sales and hence will put a positive impact on the overall company’s revenue. Oral Care product manufacturing companies are taking so many strategic decisions to cope up with the current scenario of COVID-19. The companies engaged in the manufacturing of toothpaste, mouth wash, gargle solutions among others are adopting several initiatives to accelerate the development of newer products and efficiently supply the product to different end-users. Companies have done collaboration and product launches between 2019 -2020 which supports the sustainable growth in the oral care market For instance, · In September 2020, Colgate Palmolive launched as first-ever vedshakti mouth protect spray, seeking their focus on oral hygiene during COVID-19. · Hindustan Unilever also planned to launch a mouth wash with 99 % in reducing SARS-COV-2 virus and has recently shared the preliminary data. · In April 2020, GlaxoSmithKline Consumer Healthcare Limited (India) merged with Hindustan Unilever Limited (HUL), with HUL responsible for the distribution of GSK’s Consumer Healthcare brands in India, including its leading oral healthcare brand, Sensodyne. · In April 2020, Perrigo Company plc (Ireland) completed the acquisition of the oral care assets of High Ridge Brands (US), which includes Dr. Fresh, LLC. · In December 2019, Colgate-Palmolive Company launched Colgate Optic White Renewal Tooth Paste. · In 2020, Colgate-Palmolive comes up with a recyclable toothpaste tube which will increase the interest of the population and surge the demand for the product leading to growth in revenue of the company Thus, companies operating in the oral care market are adopting several strategies, including collaboration, agreements, acquisition, and market expansion to enhance their business. These strategic decisions by the companies are expected to provide significant opportunities for the market players operating in the oral care market. CONCLUSION As the pandemic of COVID-19 has resulted in several restrictions throughout the borders but still, manufacturers of oral care can manage their stocks. Various manufacturers have allowed their manufacturers to work in a clean and safe environment to boost up the production of oral care categorized under essential need products at various manufacturing facilities across several regions of the world helping them to maintain a continuous supply chain. However, a decrease in doctor’s visit has impacted the market but the majority of products used in oral care are over the counter product which leads to continuous demand for oral care, and by raising the prices the companies are gaining extra profit which is helping them to combat the negative effect on overall revenue.
Significant COVID-19 Impact on Wealth Management in the Information, Communication, and Technology (ICT) Sector
COVID-19 Impact on Wealth Management in the Information, Communication, and Technology (ICT) Sector ANALYSIS ON IMPACT OF COVID-19 The pandemic originated from China and spread to all over the world, so far 218 countries and territories, and 2 international conveyances have been affected with COVID-19, U.S. being on the top with cases reaching about 34.5 million, followed by India, Brazil, and then by many European countries such as Russia, France, Italy, and others. The COVID-19 cases reached big named countries with strong dominance in the global market which had adversely affected the economy globally. The spread of the Coronavirus has led to the global recession, many companies were shut down and several manufacturing facilities were put on hold. There had been disruptions in the supply chain of many industries due to restrictions in logistics and the closing of manufacturing facilities. In addition, the slowdown in the economy has lowered the spending capability of individuals and people are saving money for emergencies. The World Bank stated that the global economy is expected to reduce by 5.2% in 2020. Emerging market and developing economies (EMDEs) are expected to decrease by 2.5% and the economic activity in advanced economies may get reduced by 7% in 2020. U.S. witnessed a decline of 4.8% on an annualized basis in the first quarter of Q1-2020. In addition, the slowdown in the economy has also lowered the spending capability of individuals and people are saving money for emergencies. The Latin American region is affected by COVID-19 in both human and economic terms. The IMF World Economic Outlook stated a decrease of 8.1% in the GDP of Latin America in 2020. However, the situation has improved significantly and the market is recovering from the fall. Companies are taking several measures to overcome such scenarios and more regulations are being incorporated. Wealth management is an investment advisory service that combines other financial services for addressing the needs of affluent clients. Using a consultative process, the advisor gleans information about the client’s wants and specific situation and then tailors a personalized strategy that uses a range of financial products and services. Wealth management can encompass all parts of a person’s financial life. Instead of attempting to integrate pieces of advice and various products from multiple professionals, high-net-worth individuals may be more likely to benefit from an integrated approach. In this method, a wealth manager coordinates the services needed to manage their clients’ assets, along with creating a strategic plan for their current and future needs, whether it is will and trust services or business succession plans. As the world was confronted by the COVID-19 pandemic, economic, social, and political challenges quickly became apparent across the globe. These abrupt circumstances affected both investors and wealth management firms. IMPACT ON DEMAND AND SUPPLY CHAIN, AND LONG TERM STRATEGIES ADOPTED BY MANUFACTURERS The pandemic is bound to bring new trends in the market such as an increase in digitalization. The companies require taking strategic decisions to sustain their development in this pandemic crisis. Companies have cut short the capital expenditure to maintain their financial conditions, in addition, they also need to set the sales projection to limit their offerings and avoid any extra spending. Companies need to innovate and develop technologies according to the changing trends of society. The pandemic has boosted the growth in digitalization and this has increased the requirement of wealth management on the digital platform. Critical business workflows are being digitized to enable changes in both client behavior and accommodate field personnel working remotely. Numerous organizations are shifting their focus toward digital platforms to make their business tasks simpler. It is seen that 89% of all companies have already adopted a digital-first business strategy or plan to do so and 70% of companies either have a digital transformation strategy in place or are working on one. The increasing growth in digitalization will boost the market of wealth management during the pandemic. Moreover, in 2020, the numbers of ultra-high net worth individuals, which are generally defined as those having investable assets of more than USD 30 million, grew by 24% worldwide, the fastest rate of increase since 2003. The increase in number created a huge opportunity for growth for the global wealth management market. The market players are now taking many strategic decisions to gain their market share and profit after COVID-19. Passive investing has dominated during the recent record-length bull market, active management poses advantages during volatile and turbulent times, and the firms that transform people, process technology within their equity platforms could be better positioned to grow assets. With the shifts to virtual business practices, many wealth managers have aggressively reached out to their clients by phone to make it a ‘moment that matters’ and build further goodwill through human touch. The services which are provided by the market are now shifted towards cloud platform which is very easy and flexible to use. Integrated AI and automation enable faster portfolio development aligned with customer’s expectations. This automation will be significantly used to build a portfolio for the customers which will be another strategic decision taken by the company. With the adoption and shifting the business to virtual practices, wealth managers have aggressively reached out to their clients by phone to for making a deal and build further goodwill. The distribution channel will much change for the market after the COVID-19 pandemic and this is why many companies are looking to launch their apps and online services to cater to the clients which is also a part of the strategic decision of the companies to maintain the growth of the company. Many firms may reprioritize capital allocation plans and many look for possible mergers and acquisitions for business survival and sustenance. The COVID-19 pandemic has affected the market but the services are now shifted towards cloud platform which is very easy and flexible to use. The COVID-19 has affected the supply of wealth management services as the income of the people were affected has decreased due to the pandemic. The comprehensive wealth management services were affected and the supply chain has also got affected. The players are now trying to position themselves to thrive in the next normal. The investors saw a drop in their portfolios and were given initial market drops. CONCLUSION Pandemic has taken a toll on every aspect of life, including the global economy. With the significant downfalls in many sectors, a collaborative effort of government, industry players, and consumers can win the fight against COVID-19. It continues to inflict the world with appalling economic and social dilemmas, capable enough to leave severe backlash on the economy for the next several years. The first wave had already inflicted severe blows to the population as well as the economy. The currently experiencing second wave is expected to be more disastrous not only to the masses but also to ICT markets. As the industry slowly emerges from the crises and the next normal takes hold, the success of the wealth management firms will depend on their ability to use the crises to accelerate their digital transformation and embrace a more flexible wealth management operating model. Client interaction will change, whether by choice or necessity. Digital enablement will likely continue to be leveraged to meet business and customer needs while how and where employees work and are supervised has already changed. The wealth management companies are accommodating mobile working and flexible working schedules to maintain the operational continuity which will run the business. The companies are trying to regain their share by every means, as these firms will also likely to tap on the data and analytics to learn more about potential customers which will ultimately increase their customer base. Hence, the companies are now adopting new distribution solutions after COVID-19 which will gradually help them to increase their portfolio and services and maintain their operations in the market. Some firms may start to consider mergers or deals as the environment becomes more challenging. This will benefit the companies by generating a profit and making the supply chain stronger. Southeast Asian consumers are hungry to access wealth services via apps and online. This means many wealth relationship interactions can be shifted to apps enabling low-cost services which will also help in business continuity.
Camera hội nghị Jabra Panacast 20 lý tưởng cho cuộc họp cá nhân
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Significant COVID-19 Impact on Footwear Sole Material in Chemical and Material Industry
COVID-19 Impact on Footwear Sole Material in Chemical and Material Industry INTRODUCTION Footwear designs have continuously upgraded with the advance techniques for improvement of comfort and performance of the shoes in daily routine or specialized sports applications. In footwear, the sole of footwear is very important part as sole have to face the external environment. The sole of footwear helps to protect the feet from injury during work or performing physical activities. In 1800 wood was used for manufacturing of sole. As the time passed the demand of more rubber sole shoe was increased as it was cost effective and also more comfortable in wearing for longer duration. Sandals of leather were also introduced in 1900 which was accepted globally. The leather straps were joined with the rubber sole to manufacture the footwear. The footwear of leather and wood were heavy which cannot be weared for longer duration. So light weight material was started to be used for the manufacturing of sole of footwear. In 19th century, outsole of footwear has been changed in materials. Leather has been the traditional soling material, after 1980 only about 5% of shoes have leather soles. Now, most of soles are made of rubber or plastics, which are classed as synthetics rubber. Polyurethane is one of them that become most popular soling material for footwear. Sole material is the kind of material which is used for the manufacturing of different kinds of sole according to the application of shoe. Sole material are the kind of material which are resistant to putrefaction and enzymatic destruction and after repeated wetting-drying cycles returns back to its former soft characteristics due which material is used in the manufacturing of sole for footwear. Shoe soles are made from a variety of different materials which includes rubber, leather, polyurethane and other bio-compounds. Sole material is also used for manufacturing of inner sole which is softer than the outsole. Sole of a shoe is also known as outsole which is bottom part of the shoe. More of the times outsole comes in direct contact with the ground. Footwear sole is made up of soling materials such as: Polyurethane Polyurethane is a type of polymer which is composed of organic units which are joined by carbamate links. Polyurethanes are kind of thermosetting polymers which do not melt when heated on high temperature. Polyurethane is of different types which are methylene diisocyanate (MDI), toluene diisocyanate (TDI) and polyols. Rubber Rubber is kind of elastic substance which is obtained from exudations of certain tropical plants which is natural rubber. Rubber products are also derived from petroleum and natural gas which is called as synthetic rubber. Bio-Compounds Bio-compounds are materials which are made of several cells and other structures of organisms are known as bio chemicals compounds. In bio-compounds carbon compounds are important which make the material light weight. Several materials are being used in the production of footwear sole which can provide high comfort and light weight shoe. Different types of shoes are being used for different application due to which different materials are being used in the production of footwear sole. Polyurethanes as a soling material is comprise of almost limitless chemical formulation combinations which give designers and manufacturers freedom to create innovative designs according to the application of the shoe. The soft inner sole is more in demand among women fashionable footwear and daily wears and also for kids due to lightweight and super soft sole material which is more used in the footwear. COVID-19 IMPACT ON FOOTWEAR SOLE MATERIAL MARKET Corona virus was started from the China country and now has reached to every corner of the word. The COVID-19 has larger impact on different industries due to which the growth of the business and world is recovering in very steady pace. The pandemic have hit the economy very hard world wide as the lockdown was imposed in all the regions which have made the situation challenging for all sector for growth and also the developing actives will be done in the stager manner. No sector was immune from the effect of the COVID-19 as all the manufactures of the footwear sole material in the regions have faced the ups and down in the business due to the COVID-19 situation and unable to forecast the demand of the footwear in the market. The demand for the footwear sole material has fallen in the industries due to the lower production of the footwear in the global market. The export and import of the footwear sole material in different countries have fallen down due to the pandemic situation created by COVID-19. The big brands or manufactures are producing at 25%-30% of their full capacity as demand of the footwear has fallen in the market. Government has imposed the lockdown rules in the entire region due to which people are setting at their home. The demand for the light weight sole material in the footwear have fallen down in pandemic no physical activities were going on which lower the demand for sport shoes in different games and physical activities. Different types of footwear sole are used in different type of footwear functionality. Due to lockdown in several manufactures activities were on halt, the demand of footwear has fallen down in the industries due to which the demand for footwear sole materials have decline. The cascading effect of the spread of the corona virus can also be seen on the foot wear industry. Footwear industry have also have to face the pandemic situation which created by the COVID-19. The production in the footwear industry has been on halt due to the lock down and shortage of the labor in the factory. The virus is taking a massive toll in the economic front, shutting down businesses, curbing international travel and impacting production lines of major global businesses. On evaluating footwear industry in the countries, the major brands have shut down their stores, and some of them have also delayed their new collection release which has lowered the demand for the footwear sole material in the market. FIGURE 1 NEW PRODUCT INTRODUCTION RATE (2019 –2020) From the above diagram we can interpret that the introduction of the new footwear models in 2020 was fallen down as in 2019 introduction of athletics shoes and sneakers was 11.00% which fall to 4.15% in 2020. In 2019 introduction of boots was 3.00% which fall to 5.00% in 2020. In 2019 introduction of heeled shoes was 12.00% which fall to 5.00% in 2020. With the decline in the introduction of new products in the market will have negative impact on the demand for footwear sole material in the market. IMPACT ON RELATED INDUSTRY OF FOOTWEAR SOLE MATERIAL IMPACT ON FOOTWEAR INDUSTRY According to experts of World Footwear, global footwear consumption is expected to fall by 22.5% in pandemic year. In Europe, demand of footwear declined by 27%, in North America demand of footwear is declined by 21%, and in Asia-Pacific demand of footwear is declined by 20%. The revenue of the foot wear industry has fallen down by 10%-15% in the pandemic situation as the import and export of the footwear have been declined. The demand of the footwear on all distribution channels have declined globally due to which manufactures have to face the challenge of the stock clearance. Footwear companies such as Adidas and Puma are also experiencing major effects due to the coronavirus headwinds. Most of the branded stores have been closed in the virus-driven countries. The big brands have lost the sales of USD 50 million to USD 60 million due to the outbreak. Other luxury labels are predicting serious blows to their sales too. With the falling sales of the footwear in the market have lower the demand of different footwear sole material which have impacted the global footwear sole material market. STRATEGIC DECISIONS FOR MANUFACTURERS AFTER COVID-19 TO GAIN COMPETITIVE MARKET SHARE Manufacturers of footwear sole material market have to face many difficulties due to halt in the industries which leads to low demand of footwear for all end-user segment which resulted into low demand of footwear sole material in market. The demand of footwear sole material is more in athletic shoes and also in daily wear flip-flops in the end-user segment which helped the manufacturers to earn profits from the stock as the demand for the light weight flip flops and sandals which people wear on daily basis have increased on larger extent. Manufacturers have also taken strategic decision to cover the losses which occurred due to COVID-19. Several OEMs and manufacturing industry have collaborated together and started production. In addition, fulfilling the demand of footwear sole material in the different countries manufactures are helping each other financially in business. IMPACT ON THE RAW MATERIAL PRICE Synthetic rubber is used in the manufacturing of the sole of the footwear. With decline in the demand of the footwear which resulted in decline in synthetic rubber footwear sole material during the COVID-19. Synthetic rubber footwear sole material is more used in the footwear industry as to fold and cut due to the property of flexibility which increases its demand in the footwear industry. Due to COVID–19, prices of footwear sole material are adversely affected as the downfall in demand of footwear in various industries. FIGURE 2 PRICE OF SYNTHETIC RUBBER (JANUARY 2020 –JULY 2020)(USD) From the above diagram we can infer that the price of the synthetic rubber is falling on constant rate due to the fall in the demand by the automotive, tire and footwear industry. The price of the synthetic rubber in January 2020 was 201.80 USD which fell to 192.00 USD in the month of April 2020 when the lockdown had increased the production activity have fallen down due to which the demand of the synthetic rubber have fallen down. In the month of May 2020 the price was 190.10 USD which again fell to 184.10 USD in the month of July 2020. CONCLUSION In 2020, COVID-19 has bad impact on the demand of footwear products due to which demand of footwear sole material product have fallen down. The demand of sports shoes, casual shoes have fallen down in all end-user segments which includes men, women and kids which resulted in low demand in footwear sole material in global market. The manufactures were able to earn revenue through the sale of footwear sole material for flip flops in the market during COVID-19. With the increase in sports and recreation activities and also with lifting of lockdown, the demand of different type of shoes in different industry will increase which will have positive impact on the demand of the footwear which is expected to boost the global footwear sole material market. Import and export of raw material and finished product of footwear products with other nations will help to boost global footwear sole material market in near future.