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What Impacted COVID-19 on the Global Active Pharmaceutical Ingredients (API) ?



WHO (World Health Organization) has characterized novel coronavirus as a global pandemic on March 11, 2020. This present pandemic has led to an intolerable impact on both the health and pharmaceutical structure which has ultimately created an ultimate issue on patients’ health.
APIs are the effective ingredient present in the medicine, and even small amount of active ingredients known to produce effective result. APIs are either used as single dose or as mixed dose combination in order to produce an effective medicine. However, raw materials are confused with the APIs used for making medicine, but the raw materials are the substances which are used for manufacturing of APIs and the chemical compound used for making the raw material is called as an intermediate. Even more than 10 kinds of intermediate chemical compounds are used for manufacturing of a single API. In order to manufacture API, the manufacturer has to first develop the chemical compound at first which is used for further processing of APIs. These API molecules are formed in large sized reactors. After manufacturing, these APIs are checked for purity and their effectiveness as API market is such a huge market and has a great application in the medical field there is a huge demand of close monitoring of manufacturing process. But due to continuous pandemic of COVID-19 and long term shut down has put an adverse effect on overall drug manufacturing companies. The government of several countries has reported that there is huge scarcity of APIs amid the COVID-19 pandemic. The reason behind that is the barrier across the countries border that has an ultimatum effect over the import and export facilities of medicinal product among others.
As the Indian pharmaceutical industry is largely dependent upon the China for procurement of APIs, as China is the first global leader involved in the manufacturing of low cost APIs. This has been reported that approximately 70% of APIs raw materials are imported from China to India. But the continuous pandemic of COVID-19 and barrier across the borders have a massive effect on export of good from one country to another and has led to the scarcity of APIs in India, the U.S. and the U.K. among other countries. As India is the world’s third largest supplier of low-cost and affordable generic drugs to millions of people all over the world and operates about 250 the U.S. FDA, the U.K Medicine and Healthcare product Regulatory Agency approved plants. Hence any impact on Indian APIs pharmaceutical industry led to a negative impact on overall global APIs manufacturing plants.
STRATEGIC DECISIONS FOR MANUFACTURERS
Sudden voluminous demand of APIs in order to fight against the COVID-19 has led the manufacturers to take several strategic initiatives. Large number of population affected with this COVID-19 virus and expanding spread across the world from last few months has enhanced the need of effective treatment options. To deal with the COVID-19 outbreak challenges, many APIs manufacturers are creating new strategies. To meet an actual as well as prompt increase in customer demand or to anticipated prospective increase in customer demand APIs market players are exclusively concentrating on gaining the production capacity. It is predicted that these strategies are anticipated to escalate up the company revenue and its growth in the forecasted period.
For instance;
· In January 2021, Sanofi had opened a new European company named EUROAPI which is engaged in the manufacturing and commercialization of APIs. The company established considered as one of the largest APIs manufacturing company in Europe. Through this initiative company has expanded its APIs business worldwide.
· In December 2020, DSM achieved ANVISA certification for its Colombia manufacturing plant. The certification achieved by the company allowed it to expand its commercialization of pharmaceutical premix products into other countries including Brazil among others. This certification boosted the company’s manufacturing activities.
· In October 2020, Recipharm AB signed an agreement with BIAL for boosting up the supply capabilities of APIs.
· In September 2020, Recipharm AB announced for the expansion of API facility in terms of capacity and financials in Israel. The company has invested USD 2.5 million in the clinical GMP API facility, in order to fulfill the increasing unmet demand of consumers in the API market.
· In September 2020, Jubilant Pharmova Limited signed an agreement with Saptagir Laboratories for the manufacturing of Remdesivir indicated for the treatment of COVID-19. The agreement signed helped the company to boost up the existing product portfolio and to earn a lucrative growth in the market amid COVID-19 pandemic.
· In May 2020, Sun Pharmaceutical Industries Ltd. initiated the product trial for the anti-coagulants and anti-inflammatory drugs. The clinical trial included the nafamostat and the other drug is plant based dengue drug. This initiative adopted by the company helped it to expand its business even during the COVID-19 pandemic.
· In May 2020, HIKAL ltd. has developed Favipiravir API and its intermediates. The product developed has been proved effective against the influenza viruses and is under various clinical trials for treatment of COVID-19. This initiative demonstrated the company’s strength for providing high quality medicines for its customer globally.
This signifies that various strategic initiatives adopted by the companies allow them to attain a lucrative growth even during the COVID-19 pandemic.
IMPACT ON DEMAND
Coronavirus disease (COVID-19) is one of the infectious diseases caused by a SARS-CoV-2 virus and has affected and still affecting a large pool of the population worldwide. Coronavirus disease (COVID-19) causes acute respiratory illness ranges from mild to severe pneumonia along with respiratory failure. As there is no specific and approved treatment to treat the coronavirus disease (COVID-19), the need of effective treatment is at high demand. Due to these all affirmative factors there is direct requirement of APIs for drugs manufacturing, which is indicating the future huge demand of API.
By recognizing the actual as well as prompt increase in customer demand or to anticipated prospective increase in customer demand, healthcare organization as well as government bodies’ calls on industry to increase manufacturing of APIs.
Moreover, several initiatives are taken by the government in order to meet the demand of drug manufacturing.
For instance,
· The department of pharmaceuticals (DoP, India) has announced for the proposal for the creation of new drug manufacturing facility with the investment of USD 397.13million in order to allow companies to set up the new manufacturing facilities for APIs
TABLE 1. WORLD –WIDE IMPACT OF COVID-19 ON THE PHARMACEUTICAL SECTOR
The increasing prescriptions for several kinds of illness including respiratory illness, mental illness among others has led to scarcity of drugs and API molecules used for drug manufacturing. Disproportionately high COVID-19 patient volumes putting strain on scarce drugs. Henceforth, it is estimated that global API market anticipated to boom up in the forecasted period.
IMPACT ON SUPPLY CHAIN
The COVID-19 pandemic has affected many organizations’ business environment; supply availability of various drugs has been hampered due to a large number of issues, including import and export restrictions across the countries, and continuous lockdowns that have forced suppliers to (temporarily) shut down the manufacturing facilities and supply capabilities. China occupies a predominant position in the global APIs market. China has secured a considerable market share of APIs market at global level and it exports about 17.87% of vitamin APIs among others to other countries.
Moreover, this has been reported that European pharmaceutical companies also rely on India for manufacturing of their products and India is largely dependent on China for 70% of APIs.
Since 1990, the U.S. is heavily relied on India and China for manufacturing of pharmaceutical products among others because China provides cheaper ingredients and those are not subjected to that much high regulatory rules and laws.
Moreover this has been projected out that UNICEF procures most of the pharmaceutical products from China and India and few of them from Europe as well. For Vitamin, a capsule containing Retinol UNICEF and CIK depend on same supplier and also procures from Canada.
Moreover, as the market players are totally aware of the loss that they may likely to suffer due to disruption of supply chain, they are continuously monitoring their product supplies and manufacturing capabilities in order to prevent the loss to their overall business.
For instance,
· Teva Pharmaceutical Industries Ltd., manufacturer of Accutane (Isotretinoin capsules) has announced that the company is enacting all appropriate measures in order to ensure the safe supply of their medicines and APIs.
This signifies that COVID-19 is disrupting the supply chain of APIs, it is also restricting the procurement procedure of APIs from different sources among other factors but several initiatives are taken by the manufacturers and government organizations is creating a hope for the improvement of supply chain of APIs.
PRICE IMPACT
The Coronavirus disease (COVID-19) pandemic has enormous impact on global pharmaceutical market involving APIs among others. The demand for APIs is on surge across the globe because of increasing prevalence of coronavirus disease (COVID-19) all over the world and demand of effective treatment options.
The COVID-19 pandemic has resulted in an immense increase in cost of drugs due to rising demand of drugs for treatment of several kinds of disease including HIV, cancer, epilepsy, malaria among others.
For instance,
· As per the data provided by the Pharmaceutical Export Promotion Council (PHARMEXCIL), the cost of Penicillin APIs has raised to USD 8.69 per unit in October 2020 from the USD 6.16 per unit in January 2020.
· Moreover the data procured by the APIs manufacturer suggested that there is an increase in about 13 to 18 percent of APIs prices for antibiotic involving Amikacin, Doxycycline, Azithromycin, Dexamethasone Sodium and Ornidazole among others as India imports most of them from China.
· Montelukast sodium (an anti-asthmatic drug) costs USD 705.93 to USD 787.38 per Kg in October 2020 as compared to USD 447.99 to USD 515.87 per Kg before few months.
· The prices of vitamins and penicillin have also attained a lucrative growth due to sudden rise in their prices by 40 to 50 percent as that of the original existing prices.
· India’s drug pricing regulator has also allowed pharmaceutical companies to enhance the prices of essential drugs by 50 percent including Heparin (an anticoagulant) which is in high demand to increasing risk of COVID-19 infection to patients suffering from heart attacks, strokes and lung or pulmonary embolism.
· As per the publication of April 2020, the cost of azithromycin, paracetamol, anti-inflammatory drug nimesulide APIs enhanced up to 60 to 190% during the pandemic of COVID-19. This price hike was due to shut down of China’s APIs production units. The increasing demand of several kinds of drug during COVID-19 pandemic has enhanced the demand of APIs that in turn led to APIs shortage. These shortages have an ultimatum effect on existing APIs prices.
This signifies that price of APIs hiked due to continuous coronavirus outbreak.
CONCLUSION
It is predicted that the COVID-19 pandemic outbreak has significant impact on the growth of global APIs market due to huge elevation in the demand of APIs. Moreover, many government and healthcare organization (United Nations Children's Fund (UNICEF), partners and World Health Organization are exclusively focusing on the supply of APIs and its manufacturing due to priorities and essential requirement in this crucial period. Moreover, several clinical trials also expected to provide market with a lucrative growth.
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Siginificant Impact of COVID-19 on Blood Lancet in Healthcare Industry
COVID-19 Impact on Blood Lancet in Healthcare Industry The first case of the COVID-19 pandemic was found in Wuhan, China. This pandemic has influenced the whole planet with its significant impacts on the economy and businesses worldwide. The COVID-19 spread worldwide in unprecedented ways due to its high infectious and contagious nature. As a result, the most outstanding medical challenge in the 21st century is yet to face physicians worldwide. Though the emergence of the virus can be tracked back to Asia, many European countries and the U.S. have been struck massively by the pandemic. The virus has spread across all regions ranging from North America, Europe, Asia-Pacific, Middle East and Africa up to South America. The COVID- 19 has been declared a pandemic by World Health Organization (WHO) due to its increased spread globally. After the pandemic declaration, various countries announced the complete lockdown such as the Russia, Europe and Asian countries, to decrease its spread. Regardless of the pandemic of COVID-19, the demand for blood lancets has increased in healthcare applications. Blood lancets are scalpel-type medical instruments with a double-edged blade used for various diseases for blood diagnosis procedures in hospitals, clinics and the home healthcare arena. According to the situation report of 11th May 2021 by World Health Organization (WHO) stated 157 million cases of coronavirus patients had been reported globally and 3.3 million patients are dead due to the coronavirus. America is leading in cumulative cases with a record of 64 million and 1.5 million death rates. At the same time, nearly 1.45 billion doses of COVID-19 vaccines have been administered globally. The outbreak of COVID-19 has a significant impact on the healthcare and supply chain of various medical devices and kits, including blood lancets. PRICE IMPACT The COVID-19 had a devastating impact on the global economy. The several establishments have to remain shut while others scale down the operations or put on hold expansion plans as they tried to survive the unprecedented crisis. However, the demand for blood lancets has been rising because of the increasing prevalence of diabetes patients and their routine self-care diagnostic management. Despite lockdowns and supply disruption crises during this pandemic, the companies manage online sales and delivery of blood lancets without the mandatory requirement of prescriptions. They are also maintaining fair prices owing to the high demand for blood lancets in the market. For instance, · Ever Ready First aid twist cap blood lancets of 500 counts per package costs USD 10.00, which is delivered home with high safety precautions. · Apollo Pharmacy provides home delivery for blood lancets conveniently considering the product under the counter category. The COVID-19 impact has not affected the price of blood lancets at a high level because of advanced online sales and innovative delivery options available with the utmost safety concerns. IMPACT ON DEMAND The COVID-19 pandemic has lifted the blood lancet market from its niche pedestal to the mainstream sector. However, even before the pandemic, blood lancets' demand was highly interested in rising chronic diseases such as diabetes, hyperlipidemia and more. For instance, · As per World Health Organization's (WHO) report released on 13th April 2021, the diabetes cases raised from 108 million to 422 million from 1980 to 2014, specifically higher in middle and low-income countries. · In 2019, 1.5 million death rates were directly estimated for diabetes. The rising research and technologies in the medical sector have made various types of blood lancets invade specific applications. These lancets are disposable, which surges its application for pain-free and safe blood diagnosis. This also minimizes the risk of blood transfusion and infection transmissions. The coronavirus pandemic has further increased the demand for blood lancets since COVID-19 can also be diagnosed using a blood test. For instance, · As per the 14th September 2020 published report of the U.K. Government, their coronavirus antibody test kits are delivered home for simple blood sample tests. The limited amount of blood can be drawn using finger-prick disposable blood lancets and provided to labs for 3-7 days results. In the current scenario, coronavirus's rising transmission rate has made homecare and self-diagnosis kits and procedures highly prevailing in the market. Due to its disposable nature, painless and easy usability blood lancets are highly preferred by healthcare professionals in chronic infection diagnosis. Several companies operating in other domains are eager to enter. Some have already entered the landscape of the blood lancet market to increase their revenue by meeting the emergent need of diagnosis kits and blood tests for the virus infection. The demand is further rising in local clinics and small laboratories for blood sugar and lipid testing. Furthermore, the coronavirus lockdown and lack of hospital admissions for other chronic diseases as diabetes have boosted self-monitoring diagnostic procedures among patients. Since blood lancets an ideal device for self-diagnosis, this has increased the market demand to a greater extend. The rising geriatric population and obese individuals, because of unsanitary food habits and lack of physical exercise, have increased chronic illness cases as diabetes on hype. The life-threatening diseases are compelled to be maintained and treated often, which raises the diagnosis requirements globally. Therefore, the affirmative factors boost the demand for blood lancets among patients. 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Additionally, the manufacturers are also taking crucial steps to ensure the availability of raw materials by and also they have to look into the quality of products. Therefore, manufacturers need to take necessary steps about production processes, shifting to other facilities if required, changes in quality assurance, costs and procedures related to screening workforce and offering of care if needed, changes in working hours and others to maintain their supply chain. To minimize supply chain crises, the government has been firmly monitoring the supply chain to assume that the COVID-19 outbreak may adversely impact the supply chain of a medical product, including shortages of blood lancets for various healthcare sectors countries globally or potential disruptions in supply chains. To manage such a crucial situation, many organizations are looking forward to improving and diversifying the supply chain model in all aspects. For instance, · Roche Diabetes Care has taken initiatives for uninterrupted Accu-Chek diabetes test kits and lancet products supply during this health crisis of COVID-19 lockdowns. They are supplying homes with their diabetes self-management lancets and lancing devices with online booking and free delivery without the requirement of prescriptions. · They have also reported that the COVID-19 pandemic has not impacted their supply because of the robust manufacturing facility and evolving solutions. The resulting COVID-19 pandemic has shown the various ways for supply chain management, which may be effective by innovative solutions initiated by the market players. CONCLUSION The impact of the novel COVID-19 virus is expected to leave a long-lasting effect on each healthcare sector. The outbreak of COVID-19 prompted citizens to deal with confusion regarding the virus and its management. The virus poses a risk to human life and has caused economic distress and severe emotional strain. 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How COVID-19 Impacted on Bevacizumab in Healthcare Industry ?
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In some recent studies, it was stated that Bevacizumab, an anti-VEGF drug, approved by the FDA and widely used in clinical oncotherapy, is a promising drug for ALI/ARDS in COVID-19 through suppression of pulmonary edema which have increased its demand in the market and also increasing cancer patients have also driven the market demand and supply. PRICE IMPACT The Coronavirus disease (COVID-19) pandemic has an enormous impact on the global economy market. The demand for cancer treatment products has increased along with its prices in the treatment of COVID. In addition, the sum of research and development and marketing, selling, and administrative expenses have been increased in 2020, which is driven primarily by the development expenses for COVID-19 therapies. 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IMPACT ON SUPPLY CHAIN The COVID-19 pandemic has transformed many organizations’ business environment; several problems, including export and travel ban by some producing countries and lockdowns that have caused producers to (temporarily) shut down, have disrupted supply access. Difficulties or delays in manufacturing, sales, or marketing; supply disruptions, shortages, or stock-outs at our facilities; and legal or regulatory actions all are caused due to the COVID 19 pandemic. But it does not affect the sales and supply of the drug bevacizumab that much because of the rise in new diagnoses or cancer and the efficiency of the drug in treating the COVID patients. These are some of the reasons which have maintained the supply of the drug throughout the year With the rise in demand and supply of the drugs, many manufacturing companies have launched their new products, which have increased their sales. 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Coronavirus disease 2019 (Covid-19) is an ongoing worldwide pandemic; nearly all the countries have taken initiative action under locked down and social distancing restriction. Reduction in cancer treatment across the globe has affected the demand for cancer treatment and their drugs like bevacizumab, especially in the first quarter, but after the second quarter of 2020, the demand for the drug has increased because of its Efficacy and tolerability of in patients with severe COVID-19. For Instance- Recent evidence revealed higher blood Vascular Endothelial Growth Factor (VEGF) levels in COVID-19 patients compared with healthy controls. VEGF is considered the most potent vascular permeability inducer. Numerous studies have revealed that VEGF was a key factor and a potential therapeutic target in ALI and ARDS. Bevacizumab, an anti-VEGF drug, approved by the FDA on February 26, 2004, and widely used in clinical oncotherapy, is a promising drug for ALI/ARDS in COVID-19 through suppression of pulmonary edema. Also, the increase in cancer patients and the rise in the demand for the treatment of various types of drugs have propelled the market demand and sales of major market players. For instance, · There is an increase in the sales of biosimilar drugs which includes bevacizumab, for major market players. For instance, the manufacturing company Pfizer Inc., the sales of biosimilar segment is increased from USD 1,527 million to USD 911 million with the increase in demand for the drugs in COVID patients and the cancer treatment. STRATEGIC DECISIONS FOR MANUFACTURERS A large population is affected by this COVID-19 virus, and its spread is expanding worldwide for the last few months. To deal with the COVID-19 outbreak challenges, many bevacizumab and biosimilar market players are creating new strategies. The company is now opting for digital media such as telecommunication, mobile applications, webinars, and other digital media to support patient requirements to tackle the pandemic situation and increase the company sales with the increasing demand and growth. Moreover, to accomplish the market demand, small market players are utilizing the partnership agreement strategy. It is predicted that these strategies are anticipated to escalate up the company revenue and its growth in the forecasted period. They have launched new products and formed strategic alliances with each other to carry on the supply during the pandemic. For instance- · In 2020, Amgen Inc. had advanced their innovative pipeline, successfully integrated MVASI, acquired in November 2019, a biosimilar to Avast in (bevacizumab), and has advanced their international expansion continued to provide an uninterrupted supply of their medicines globally through the COVID-19 pandemic · In May 2020, the Food and Drug Administration approved atezolizumab in combination with bevacizumab (TECENTRIQ and AVASTIN, Genentech Inc.) for patients with unrespectable or metastatic hepatocellular carcinoma who have not received prior systemic therapy CONCLUSION It can be concluded that the COVID-19 pandemic has a positive impact on the global bevacizumab market with the increase in the price, supply, and demand of the bevacizumab. However, in the crisis call, pharmaceutical market players, government bodies, and healthcare organizations work closely with healthcare professionals, customers, and patients for the betterment of public health and to fulfill the demand. However, companies and government bodies exclusively concentrate on how they can make the most effective and best contribution to control the spread of the virus and save lives. They are also ramping up the production of essential medication to a new level and ensure that speed doesn’t affect or destroy the quality of products.
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According to the new market research report "Pharmaceutical Packaging Equipment Market by Product (Aseptic Packaging, Blister, Strip, Bottle, Tube, Carton, Case Packer, Wrapping Machine, Palletizing, Labeling & Serialization), Type (Tablet, Powder, Cream, Syrup, Aerosol), Region - Global Forecast to 2025", published by MarketsandMarkets™, the global Pharmaceutical Packaging Equipment Market size is projected to reach USD 10.4 billion by 2025 from USD 7.3 billion in 2020, at a CAGR of 7.4% from 2020 to 2025. Browse in-depth TOC on "Pharmaceutical Packaging Equipment Market" 276 – Tables 48 – Figures 330 – Pages Download PDF Brochure:-https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=19845828 The growth of the global pharmaceutical packaging equipment industry is driven by the rapidly growing generic and biopharmaceutical markets, growth in OTC drug sales, rising need for flexible and integrated packaging equipment, increased offshore manufacturing in the pharmaceuticals market, and the introduction of regulatory standards on packaging and stringent norms against counterfeiting. Primary packaging equipment accounted for the largest share in the market in the forecast period. On the basis of product, the pharmaceutical packaging equipment market is segmented into primary packaging equipment, secondary packaging equipment, and labeling and serialization equipment. In 2019, the primary packaging equipment segment accounted for the largest share of the market. The main function of primary packaging is to restrict climatic, chemical, or biological hazards that cause deterioration. The rising need for the aseptic filling and sealing of drug molecules into sterile containers and the increasing demand for parenteral vials and prefillable syringes are supporting the growth of this segment. Liquid packaging equipment expected to show the highest growth in the forecast period. Based on type, the pharmaceutical packaging equipment market is segmented into liquid, solid, semi-solid, and other packaging equipment. In 2019, the liquid packaging equipment segment accounted for the largest share of the market, followed by solid and semi-solid packaging equipment segments. The largest share can be attributed to the wide range of applications of liquid pharmaceutical dosage as they can be administered via either the oral or the parenteral route. Their palatability makes them a product of choice for geriatric and pediatric patients. Get 10% Customization on this Research Report :-https://www.marketsandmarkets.com/requestCustomizationNew.asp?id=19845828 Europe to hold the largest share in the global market during the forecast period of 2020–2025. Geographically, the pharmaceutical packaging equipment market is segmented into North America, Europe, the Asia Pacific, Latin America, and Middle East & Africa. Growth in the European market is driven majorly by the high pharmaceutical production, increasing demand for flexible packaging equipment by major pharmaceutical manufacturers, and the rising focus on product diversification by companies, driving the demand for innovative packaging equipment. Regulatory changes are also compelling pharmaceutical manufacturers to replace their older equipment with new equipment to adhere to the changing standards. The prominent players in this market are Syntegon Technology (Germany), IMA S.p.A. (Italy), Körber AG (Germany), Uhlmann Group (Germany), OPTIMA Packaging Group (Germany), Romaco Holding (Germany), Marchesini Group (Italy), ACG Worldwide (India), Coesia S.p.A. (Italy) and MULTIVAC Group (Germany).
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Significant Impact of COVID-19 on Advanced Anesthesia Monitoring Devices in Healthcare Industry
COVID-19 Impact on Advanced Anesthesia Monitoring Devices in Healthcare Industry The first case of the COVID-19 pandemic was found in Wuhan, China. This pandemic has influenced the whole planet with its major impacts on the economy and businesses across the globe. The COVID-19 spread worldwide in unprecedented ways due to its high infectious and contagious nature and lack of availability of its vaccine. As a result, the greatest medical challenge in the 21st century is yet to be faced by the healthcare sector worldwide. Many European countries along with the U.S. and the Asia Pacific have been struck massively by the pandemic. The virus has spread across all regions ranging from the Middle East and Africa, Europe, Asia-Pacific, North America, up to South America. The COVID-19 has been declared as a pandemic by WHO due to its increased spread across the globe. Following the pandemic’s declaration, numerous countries have declared the full lockdown, including the U.S., Germany, India, and China to limit its spread. The overall fall in the demand for advanced anesthesia monitoring devices was observed during the COVID-19 pandemic due to a decrease in the number of surgeries. The effect on the healthcare industry has also been dramatically impacted and a huge pressure is being created on healthcare services that are already stressed across the globe. Emerging technological advancements has further escalated the demand for advanced anesthesia monitoring devices in the market. IMPACT ON PRICE The coronavirus disease (COVID-19) pandemic has had an enormous impact on the global advanced anesthesia monitoring devices market. The demand for advanced anesthesia monitoring devices services across the globe is anticipated to decrease due to the patient pool which cancelled their scheduled and elective surgeries. If the COVID-19 continues to spread for prolong period, then it is estimated that the demand for advanced anesthesia monitoring devices services will downgrade by developed as well as developing countries. Moreover, top advanced anesthesia monitoring devices importer countries such as United States, Europe is primarily concentrating to deal with Coronavirus (COVID-19); owing to this reason demand for these advanced anesthesia monitoring devices has decreased from the United States followed by Italy. If the lockdown continues to stretch for long period then a huge reduction may take place in several surgeries, which may lead to a decrease in the price of advanced anesthesia monitoring devices. Resulting it is predicted that COVID-19 has an adverse impact on the price of advanced anesthesia monitoring devices. IMPACT ON DEMAND Coronavirus disease (COVID-19) is an infectious disease caused by a SARS-CoV-2 virus while a large pool of the population is affected by this COVID-19 virus. Coronavirus disease (COVID-19) causes acute respiratory illness ranges from mild to severe pneumonia with respiratory failure. To minimize the spread of COVID-19, nearly all the countries have taken initiative action by the virtue of locked down and social distancing restriction. Owing to such affirmative factors, demand for advanced anesthesia monitoring devices has been minimized. But due to lockdown and social distancing restrictions, the majority of the patient pool are preferring virtual vising through video calling or telehealth video visiting. For instance, · According to the report published by the British Journal of Surgery, in May 2020, an estimated 585,000 elective surgeries were postponed in the 12-week lockdown in India alone, and 28.4 million elective surgeries worldwide are expected to be cancelled or postponed. Thus, the cessation of surgical procedures is the major factor that is likely to hamper the usage of advanced anesthesia monitoring devices. STRATEGIC DECISIONS OF GOVERNMENT AND MANUFACTURERS A large pool of the population affected by this COVID-19 virus and spread is expanding across the world for the last few months. To deal with the COVID-19 outbreak challenges, many advanced anesthesia monitoring devices market players are creating new strategies. To tackle the pandemic situation and increase the company revenue and growth, the company now opting for digital media such as telecommunication, mobile applications, webinars, and other digital media to support the patient requirement. Moreover, to accomplish the market demand, small market players utilizing the partnership agreement strategy. It is predicted that these strategies are anticipated to escalate up the company revenue and its growth in the forecasted period. IMPACT ON SUPPLY CHAIN The COVID-19 pandemic has transformed many organizations’ business environments; supply availability has been hampered by several issues, including export and travel restrictions by some producing countries, and lockdowns that have forced suppliers to (temporarily) shut down. To minimize supply chain crises, healthcare organizations have been firmly monitoring the supply chain with the assumption that the COVID-19 outbreak may adversely impact the supply chain of medical devices, including shortages of advanced anesthesia monitoring devices or potential disruptions in its supply chains. To manage such a crucial situation many organizations are looking forward to improving and diversify supply chain models in all aspects. A diversified supply chain model is anticipated to minimize the export of medical devices as well as increase end-to-end visibility. The resulting COVID-19 pandemic has shown the various ways for supply chain management which may be effective within a remote working environment. CONCLUSION It can be concluded that the COVID 19 pandemic situation has an enormous impact on the global advanced anesthesia monitoring devices market due to a decrease in the number of surgeries. However, companies as well as government bodies exclusively concentrating on how they can make the most effective and best contribution to control the spread of the virus and save lives. They also ramping up the production of essential medication to a new level and ensure that speed does not affect or destroy the quality of products.
Significant COVID-19 Impact on Hearing Aids in Healthcare Industry
COVID-19 Impact on Hearing Aids in Healthcare Industry The COVID-19 has affected the global hearing aids market. The persistence of COVID-19 for a longer period increased the demand for hearing aids services across the global region. During, COVID-19 pandemic, the countries were expecting a large number of patients with the impaired hearing which results as one of the symptoms of COVID-19 disease. Moreover, the increased geriatric population across the globe with the hearing inabilities due to their age is a major factor driving the global hearing aids market. The rising number of patients suffering from hearing inabilities and hearing loss coupled with the increasing demand for the advanced level and effective technology hearing aids to provide to the patients will boost the growth of the market. The demand for hearing aids for the patients which is a rare symptom of COVID-19 has overall decreased during the COVID-19 crisis. IMPACT ON THE DEMAND OF THE GLOBAL HEARING AIDS MARKET The global hearing aid market was negatively impacted by the pandemic. The hearing care industry is dependent on close customer contact. Due to stringent precautionary measures announced by the government, close human contact was discouraged or required special measures in the clinics and the audiology shops. As a result, less severe hearing loss-related procedures were delayed during the pandemic which impacted the sales of hearing aids. Despite these challenges, manufacturers implemented measures to meet the high demand for timely professional hearing care. Due to product innovation and re-inventing supply chain, major players in the hearing aids market were able to sustain demand and cater to the hearing healthcare market even during the pandemic. INITIATIVES BY THE MANUFACTURERS: There are some important initiatives taken up by the key market players to overcome the COVID-19 impacts on the current market scenario. Some of them include the launch of technologically advanced devices in the global market to meet the growing demand for hearing aids. For instance, In 2020 GN hearing launched Resound ONE that solves one of the most enduring challenges for people with hearing loss. This solution places an additional microphone inside the ear canal with a microphone and receiver in-ear design that uses the unique shape. Manufacturers are trying to meet the growing demand and improving their product portfolio to acquire a larger market share by launching new products that are preferred by the consumers. For instance, · In January 2021, Oticon Inc launched Oticon More, a new hearing aid that builds on the company’s proven brain hearing approach to provide the brain optimum input for better speech understanding with less approach. · In March 2020, Widex launched the moment hearing device. The widex moment has the classic widex signal pathway which is paired with a second ultra-fast signal pathway that adds extra gearing to the platform. Therefore, these innovative launches made by the manufacturers across the market during the COVID-19 and post-pandemic period are expected to increase their sales and revenue by meeting the growing demands of the patients in the market. IMPACT ON THE SUPPLY CHAIN Although there was a demand for hearing aids among consumers around the globe region due to the increasing hearing loss, the COVID-19 has disrupted the supply chain as well as consumer’s willingness to adopt elective healthcare. The COVID-19 has negatively impacted the market supply chain due to the lack of labor and transportation of the raw materials. Due to the sudden outbreak of the COVID-19 pandemic, the governments in the world have declared a strict lockdown to control the spread of disease. This has majorly affected the supply chain as there is not sufficient labor in the manufacturing facilities, resulting in the lack of hearing aid products in the market. Due to the sudden burden of lockdown, the raw materials have not been shifted from the source places by causing a severe scarcity of raw materials for the manufacturers. This has affected the export of hearing aid products to other needful countries. However, in the post lockdown period, the manufacturers have recovered from the scarcity of the raw materials and resumed production. CONCLUSION The sudden onset of the COVID-19 pandemic has resulted in negative impacts on the supply chain of the global hearing aids market. The COVID-19 has caused lots of health issues including the hearing inability in rare cases which increased demand for hearing aids. This is positively impacting the growth of the global hearing aids market as there is an increasing geriatric population around the globe with common hearing problems. However, the increase in the hearing inability diseases among the population due to various reasons such as noise pollutions, genetic disorders among others has increased the demand for hearing aids even in the COVID-19 pandemic.
How COVID-19 Impacted on Periodontitis in Healthcare Industry ?
COVID-19 Impact on Periodontitis in Healthcare Industry Overview The COVID-19 pandemic has posed immense pressure over the healthcare industry and proved to be an unprecedented challenge to global healthcare companies. The COVID-19 pandemic has deprived hundreds of medical services and hindered several ongoing clinical trials. With the introduction of COVID-19 vaccines, new COVID-19 infections have declined, but the attack of mutant corona strain and second COVID-19 wave has led to the overall increase in mortality rate and again badly affected the healthcare industry, among others. Moreover, the upcoming delta strain of the COVID-19 virus, which has affected Singapore, Indonesia, and France, is expected to hamper the market's growth in the future. The most common symptoms associated with coronavirus disease include cough, fever, diarrhea, sore throat, and loss of smell or taste. Patients affected with COVID-19 are at increased risk of developing hepatic manifestations and also experiences damage to liver tissues. COVID-19 has led to the closure and reduced hours of dental practices except for urgent and emergency services, thus limiting routine care and disease prevention. However, regardless of the pandemic of COVID-19, increasing dental disorders like periodontal disorders among the geriatric population have increased the demand for periodontitis treatment. Periodontitis treatment among dental diseases includes aerosol-generating procedures, including aerosol implants that can increase the chances of viral transmission. The pandemic offers an opportunity for the dental profession to shift more toward non-aerosolizing, prevention-centric approaches to care and away from surgical interventions. Direct effects of COVID-19 on oral health include periodontitis, vesiculobullous lesions, and necrotizing periodontal disease. IMPACT ON PRICE The outbreak of the coronavirus disease pandemic (COVID-19) is on the increase and is disrupting lives around the world. Lockdowns, isolation, and widespread closures are being implemented to slow the spread of the virus to millions of lives saved. Vaccination is going on at an accelerated pace so as to deal with such debilitating viral diseases. Several countries are facing a multi-layered crisis, including strains on health systems, among others. With the sudden increase in COVID-19 cases, the people's concerns for their better health have also increased, and the link between oral health and COVID-19 infection also expand the health to oral. The Asian healthcare industry heavily relies on medical devices manufactured in China, which significantly impacts costs as medical devices are not properly available. For instance, Moreover, a large number of medical devices are manufactured in different locations, and the supply of medical equipment is reduced due to restrictions on movement from one location to another. So, the costs have increased for dental devices, among other medical devices. Thus, it signifies that the COVID-19 pandemic has led to an increased price of periodontitis treatment products during the fiscal year 2019-2021. IMPACT ON DEMAND The outbreak of the coronavirus is a result of various markets around the world. It is the cause of lockdown and isolation, which ultimately has an impact on global economic activity. COVID-19 is expected to create a sharp drop for consumables and dental implants. However, due to accelerating demand, a rapid recovery is expected once the dust settles. It includes the orthopedics, cardiology, and dental product industries, among others. These factors have forced market players to strengthen further business continuity, manufacturing facilities, and the global supply chain. The rising awareness of oral hygiene amidst the COVID-19 pandemic has increased the demand for a product required for oral care. The increasing studies for SARS-COV-2 indicated that proper oral hygiene had been reported to decrease infection chances, increasing the demand for mouth care products. However, due to restrictions and aims to reduce COVID-19 transmission, 30% of respondents had visited a dentist less frequently during the pandemic. For instance, · In March 2020, Zimmer Biomet reported a significant and sudden global drop in the volumes of elective procedures. As a result, based on preliminary unaudited financial results, Zimmer Biomet estimated that revenue growth for the first quarter of 2020 would be approximately -9.5 to -10.5% on a reported basis and -8.5 to -9.5% on a constant currency basis compared to the first quarter of 2019. The company is engaged in manufacturing dental implants and dental membranes, and the closure of dental practices has impacted the overall company's sales Zimmer Biomet expects the decline in volumes of elective procedures seen in the first quarter to continue to have a significant negative impact in the second quarter of 2020. Given the continuing uncertainty, the company is currently unable to quantify the impact on its operating results, its financial situation, and its cash flows, which could be significant for 2020. The impact of COVID-19 has dramatically decreased the number of patients who go for dental procedures, including periodontitis treatment, as there is a high chance of adverse health effects of COVID-19. IMPACT ON SUPPLY Various companies are facing a large number of challenges due to the coming of the novel coronavirus. One such issue is the uncertainty surrounding the impact of COVID-19 on medical device industry supply chains. Amalgamation is expected in the dental industry. Manufacturers of large dental products can engage in small businesses. Dental firms involved in supply chain distribution can diversify by producing additional consulting firms or dental equipment and supplies. The companies are at risk, and the ability to retain independent agents and distributors who sell their products depends on a limited number of suppliers for key raw materials. Up till now, dentistry has been facing its darkest hour because of the growth and spread of the coronavirus pandemic. Dental clinics all over the U.S. have been closed for more than two months. Given that the pandemic is still on the growth curve, there is no revival hope anytime soon. It thus signifies that due to continuous lockdown and several restrictions by government authorities, the companies and patients are facing disruption of the supply chain for oral care. However, oral care is categorized under essential care, which lowers the effect of supply chain disruption during COVID-19. STRATEGIC DECISIONS OF MANUFACTURERS Collaboration, agreements, strategic initiatives, and product launches by market players will help them expand their product portfolio and provide appropriate products to the consumer. It will lead to increased product sales and, hence, will positively impact the overall company's revenue. · The COVID-19 has negatively impacted the dentistry market. According to the Health Policy Institute (HPI) March 23 survey report, except for emergency patients, 76 percent of dental practices were closed, 19 percent were completely closed, and 5 percent were open despite the decline. In the week of April 6, 79 percent of dental practices were closed, except for emergency patients, 16 percent were completely closed, and three percent were open despite a decrease in the number of patients During this time of COVID-19 challenge and disruption, Zimmer Biomet, Dentsply Sirona, among others, is adopting several steps to maintain their position in the market and continuously attain lucrative growth. For instances, · Zimmer Biomet has positioned the company to help healthcare systems, clients, and patients now. It has adopted steps to further strengthen the business continuity across its manufacturing facilities and overall supply chain, manufacturing modulation production · Dentsply Sirona has also stated that the company is closely monitoring its global manufacturing sites and raw material supply chains to avoid product delivery delays. Moreover, the company is taking appropriate precautions and implementing safety protocols in order to protect its employees in the context of COVID-19. The company has also launched an illness prevention and awareness intranet site for providing support and guidance to its employees Moreover, by keeping in mind the rising prevalence of periodontitis, market players are adopting initiatives to fulfill patient's and professional's demands. Thus, companies operating in the periodontitis market are adopting several strategies, including agreements and market expansion, thereby enhancing their business. These strategic decisions by the companies are expected to provide significant opportunities for the market players operating in the oral care market. CONCLUSION As the pandemic of COVID-19 has resulted in several restrictions throughout the borders, manufacturers of periodontitis products can still manage their stocks. Various manufacturers have allowed their employees to work in a clean and safe environment to boost the production of essential products at various manufacturing facilities across several regions of the world, helping them maintain a continuous supply chain. However, decreased patient visits have impacted the market, but the rising demand for periodontitis treatment leads to continuous demand for dental implants. Moreover, by raising the prices, the companies are gaining extra profit, helping them combat the negative effect on overall revenue.
Refurbished Medical Equipment Market is Set to $21.2 billion by 2025
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How COVID-19 Impacted on Nutraceutical Packaging in Healthcare Industry ?
COVID-19 Impact on Nutraceutical Packaging in Healthcare Industry The COVID-19 pandemic has impacted the food and beverages industry including the nutraceutical market by up surging in their consumption globally. Each and every segment of nutraceutical industry has been impacted either positively or negatively due to the COVID-19 pandemic. The Nutraceutical packaging market is subjected to have the positive impacts due to the sudden outbreak of COVID- 19. This is mainly due to the consumer awareness about the importance of consuming the nutraceuticals in order to boost their immunity to fight the pandemic period. The demand for the nutraceuticals has been increasing across the globe due to the changing lifestyle of the health conscious consumers. This increase in the demand for the nutraceuticals have positively affected on the nutraceutical packaging market. AFTERMATH OF COVID-19 AND GOVERNMENTS INITIATIVE TO BOOST THE GROWTH OF THE MARKET The aftermath of the COVID- 19 has a very positive impact on the market of the nutraceutical packaging across the globe. As the consumers are more incline to buy health and wellness products such as nutraceutical products which further increased the sales and revenue of the market players. The post pandemic period people are more concerned towards the product’s safety and shelf life which further drive the demand for advanced and innovative packaging materials for nutraceuticals. Also, with the growing awareness and growing social media nutritional trends influencing population all around the world will increase drive the demand for nutraceutical which will further boost the growth of global market. Many governments have taken initiatives for the nutraceutical packaging as they have been focusing on ways to improve the consumer’s health and wellness. The government initiatives to support industries in order to manufacture innovative packaging products will boost the growth of the market. For example, · European Union (EU)- funded project NanoPack aims to develop packaging solutions that increase product life after packaging by using novel anti-microbial surface application on the food packaging product surface. The Nanopack antibacterial film extends the shelf life of the product by two days. This two day increase in shelf life increase product stability by 40%. Therefore, such initiatives taken up by the governments which aim to help the manufacturers to manufacture safe products for the nutraceutical packaging will propel the growth of the market. STRATEGIC DECISIONS OF MANUFACTURERS AFTER COVID-19 TO GAIN COMPETITIVE MARKET SHARE To deal with the COVID-19 outbreak challenges many nutraceutical packaging market players are creating new strategies. It is predicted that these strategies are providing high chances to escalate up company revenue and its growth in the forecast period. Similarly, growing opportunities in innovative packaging solutions is attracting a larger consumer base for the nutraceutical packaged products. Increase in the demand for the nutraceuticals has made companies to launch the new products in spite of the COVID- 19 challenges and to gain a larger market share. Despite of the COVID – 19 pandemic outbreak, the manufacturers have been creating new opportunities by themselves by participating in exhibitions in order to spread the awareness about the nutraceuticals and their nutritional benefits which helps in boosting the immunity of the consumers. For instance, · In 2021, MJS packaging announced that they will exhibit for the first time since the start of COVID- 19 pandemic at the 2021 Cannabusiness international market place Michigan summit and expo in Michigan. Therefore, such product launches, exhibition of the products at the expos and vents in order to increase their consumer base are the strategic decisions which are taken up the market players to gain larger market share. PRICE IMPACT The COVID-19 had a terrible impact on the global economy. Many establishments have to remain shut while others scale down their operations or put on hold expansion plans as they survive the unprecedented crisis. The other impact of the COVID-19 pandemic outbreak is the delay or fluctuation of raw material supply for nutraceutical packaging manufacturing. This fluctuation has resulted in increase in price of raw material, which has impacted the prices of nutraceutical packaging products. IMPACT ON DEMAND There is a rapid increase in demand for the nutraceuticals increasing popularity for the nutraceutical packaging as well. Demand for the increased shelf life of food products across the globe is expected to increase the growth of the market in the COVID-19 period as well. There is an increasing consciousness about health and weight management is playing a crucial role in the demand for the global nutraceutical packaging market. On an average, the consumers have increased have increased their monthly spending on vitamins, minerals and supplements products by 10-15% since the COVID- 19 began. The increase in the awareness among the consumers about the consumption of the nutraceuticals is that they can build the immunity that is highly required in the COVID- 19 pandemic period has positively affected on the nutraceutical packaging as well. With the rise in the consumption of the nutraceutical in order to maintain the good health and fitness, the demand for the nutraceutical packaging also increased. Therefore, there has been a constant increase in the demand for the nutraceuticals which positively affected on the nutraceuticals packaging market as the packaging of the vitamins, minerals and other dietary supplements is the major factor that attracted the attention of the consumers. IMPACT ON SUPPLY CHAIN During the pandemic situation, the supply chain was majorly disrupted due to a lack of resources and transportation. Also, the governments across the world have implemented various restrictions and lockdowns to prevent the spread of the disease. In the same way, many governments have restricted the movement of goods across the countries and the entire supply chain was distorted. Owing to the disrupted supply chain, the transportation of raw materials has been interrupted and the production of nutraceutical packaging products was halted. Similarly, the manufacturers aren’t able to visit the customers such as nutraceutical companies to provide them with the packaging materials due to the implementation of lockdowns across the various parts of the world. Thus the demand for nutraceutical products has been tremendously increasing whereas the packaging materials production has been disrupted. As a result, the COVID- 19 pandemic has negatively impacted on the supply chain of the nutraceuticals packaging market. CONCLUSION COVID- 19 pandemic has taken a toll on the population and economy. A collaborative effort on governments, public health departments and hospital fraternity to fight corona virus has led to the economic slowdowns, lockdowns and extreme public safety measures. Due to the increasing health conscious ness among the consumers, the demand for the nutraceuticals has been increasing constantly in the COVID – 19 pandemic periods. This is mainly because of precautionary measures which are followed by the consumers for the COVID-19 which in involves the intake of nutraceuticals. However, the supply chain has disrupted during the outbreak scenario because the demand is more for these products. As unlocking of the lockdown being started in various regions of the world, it is expected that the supply chain became normalized for the market.
mHealth Solutions Market worth $213.6 billion by 2025 - Exclusive Report by MarketsandMarkets™
According to the new market research report "mHealth Solutions Market by Connected Devices (Glucose & Blood Pressure Monitor, Peak Flow Meter, Pulse Oximeter), Apps (Weight Loss, Women Health, Diabetes Management, Mental Health), Services (Remote Monitoring, Consultation) - Global Forecast to 2025",is projected to reach USD 213.6 billion by 2025 from USD 50.8 billion in 2020, at a CAGR of 33.3 % during the forecast period. The growing adoption of smartphones, increasing penetration of 3G/4G networks, rising focus on cost containment in healthcare delivery, and the increasing demand for home healthcare services are some of the key factors driving the growth of this market. Browse in-depth TOC on " mHealth Solutions Market 303 -Tables 43- Figures 291- Pages Download PDF Brochure: - https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=1232 The mHealth apps segment accounted for the largest share of the mHealth solutions market in 2019 Based on product and service, the mHealth apps segment accounted for the largest share of the mHealth solutions market in 2019. The large share of this segment can be attributed to the high and growing penetration of smartphones and healthcare apps and the rising incidence of chronic and lifestyle-related diseases across the globe (coupled with the effective utilization of apps in chronic disease management). Based on region, North America accounted for the largest share of the mHealth solutions market in 2019 Based on region , the mHealth solutions market is segmented into North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. North America accounted for the largest market share in 2019. This is due to the increasing penetration of smartphones, rising prevalence of chronic and lifestyle disorders, increasing healthcare costs, increasing demand for better healthcare services, government initiatives to promote digital health, robust penetration of 3G and 4G networks, and the rising awareness of self-health management. Request Sample Pages: - https://www.marketsandmarkets.com/requestsampleNew.asp?id=1232 The prominent players in this market are Medtronic plc (Ireland), Apple, Inc. (US), AirStrip Technologies (US), AliveCor, Inc. (US), Nike, Inc. (US), Koninklijke Philips N.V. (Netherlands), Johnson & Johnson (US), Omron Corporation (Japan), BioTelemetry, Inc. (US), athenahealth, Inc. (US), AgaMatrix, Inc. (US), Withings S.A. (France), and iHealth Labs, Inc. (US).
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Significant COVID-19 Impact on Juvenile Polyposis Treatment in Pharmaceutical Industry
COVID-19 Impact on Juvenile Polyposis Treatment in Pharmaceutical Industry The first case of the COVID-19 pandemic was found in Wuhan, China. This pandemic has influenced the whole planet with its major impacts on the economy and businesses across the globe. The COVID-19 spread worldwide in unprecedented ways due to its highly infectious and contagious nature and the lack of availability of its vaccine. As a result, the greatest medical challenge in the 21st century is yet to be face d by physicians worldwide. Though the emergence of the virus can be traced back to Asia, many European countries and the U.S. have been struck massively by the pandemic. The virus has spread across all regions ranging from North America, Europe, Asia-Pacific, South America, and Africa up to the Middle East. The COVID-19 has been declared as a pandemic by World Health Organization (WHO) due to its increased spread worldwide. The outbreak of COVID-19 has had a great impact on the healthcare and pharmaceutical industries and a major impact on the global juvenile polyposis treatment market. Juvenile polyposis syndrome is a genetic disorder characterized by the growth of polyps along the gastrointestinal tract lining. Juvenile polyposis treatment can be done in two ways. When many polyps are present, surgery may be done to remove a part of the stomach or intestine. When there are fewer polyps, they can be removed during endoscopic examination. The decreasing number of surgical and non-surgical procedures during the pandemic will negatively affect the growth of the global juvenile polyposis treatment market. PRICE IMPACT The COVID-19 had a terrible impact on the global economy. Many establishments were forced to remain shut while others had to scale down their operations or put on hold expansion plans as they tried to survive the unprecedented crisis. Another impact of the COVID-19 pandemic is the delay in surgical and non-surgical procedures to treat selective diseases. Patients are preferring alternative treatment procedures that have no requirement for physically appearing in hospitals or clinics. Consequently, the demand for medical devices used to treat juvenile polyposis has decreased due to the decrease in various surgical and non-surgical procedures during the pandemic. For instance, · According to a study performed by BMJ Journals in the U.K., a weekly average of 35,478 endoscopic procedures were performed during the pre-COVID period. After the COVID-19 pandemic, these numbers reduced by 12 percent · According to an article by PMC, diagnosis of colorectal cancers was considerably delayed during the pandemic, which had a huge economic and workload burden on the gastroenterologists, surgeons, and oncologists Suppose the COVID-19 keeps on spreading like this for a long period. In that case, it is estimated that the demand for medical devices like endoscopes and colonoscopes which are used to treat juvenile polyposis, will downgrade by top importer countries. Suppose the lockdown continues to stretch for a longer period than anticipated. In that case, a huge drop is expected in non-surgical and surgical procedures worldwide, including the treatment of juvenile polyposis. Consequently, demand for the medical devices used in the procedure is anticipated to be minimized, which may decrease the price of the overall juvenile polyposis treatment procedure. Thus it is predicted that COVID-19 negatively affects the price of the juvenile polyposis treatment market. IMPACT ON DEMAND Coronavirus disease is an infectious disease that is caused by a SARS-CoV-2 virus. Currently, a huge population pool is affected by this COVID-19 virus. Coronavirus disease causes acute respiratory illness, ranging from mild to severe pneumonia with respiratory failure, and in rare cases, it is also associated with major cardiac complications. In order to reduce the spread of COVID-19, nearly all the countries have taken initiative action by lockdown and social distancing restriction. Due to affirmative restrictions, sudden shrink occurred in various surgical and non-surgical procedures requiring the patients' physical presence. Reduction in surgical and non-surgical procedures across the world has adversely affected the demand for the treatment of juvenile polyposis. Due to lockdown and social distancing restrictions, most patients prefer virtual vising through video calling or telehealth video visiting. Telehealth video visits are demanding alternative treatment such as medication for the treatment of certain diseases. Consequently, the growth of the juvenile polyposis treatment market is anticipated to downgrade as this procedure needs the patient to be physically present. For instance, · According to CDC, in 2019, 43 percent of the health centers were capable of providing telehealth services, while in 2020, during the COVID-19 pandemic, it was reported that 95 percent of the health centers were providing telehealth services · According to May 2020 article published by PMC, COVID-19 had a huge impact on surgical practice. There was a huge decline in the number of surgical procedures taking place, and also the surgeons are recommending safe, non-surgical alternative options to treat their patients during the pandemic IMPACT ON SUPPLY CHAIN COVID-19 has led to a disruption in the supply chain of medical devices, which are essential for treating and diagnosing juvenile polyposis syndrome. In different countries, diagnoses of other diseases have slowed down due to increased pressure to diagnose COVID-19. This led to a significant delay in diagnosing juvenile polyposis syndrome, which ultimately reduced the number of treatment procedures. The COVID-19 pandemic has truly transformed some organizations' business environment; the organizations' supply chain has been hampered by several issues, including export and travel restrictions by some countries and lockdowns that have forced suppliers to shut down in the majority of the cases temporarily. For instance; · According to an article by The Hindu published in May 2021, China holds the majority of the market for raw materials, and unfortunately, the pandemic leads to global restriction along with series of lockdowns which leads to disrupted supply chain To minimize supply chain crises, healthcare organizations have been firmly monitoring the supply chain with the assumption that the COVID-19 outbreak may adversely impact the supply chain of a medical device or equipment. This includes shortages of endoscopes and colonoscopes required to treat juvenile polyposis or potential disruptions in its supply chains. To manage an adverse situation, many organizations have looked forward to improving and diversifying the supply chain model in all aspects. A diversified supply chain model anticipated minimizing the export of medical devices and equipment and increasing end-to-end visibility. The COVID-19 pandemic has shown various supply chain management methods, which may remain effective within a remote working environment. STRATEGIC DECISIONS FOR MANUFACTURERS COVID-19 can hamper the production and supply chain of endoscopes and colonoscopes, which are used in the treatment procedure of juvenile polyposis. Still, it also provides companies to improve their business by different means. Different companies made different strategic decisions to maintain their supply chain constantly and reduce the spread of the virus among their employees. They made proper decisions to maintain a safe work environment. For Instance, · Olympus, a leading manufacturer and supplier of endoscopes and colonoscopes, has maintained proper supplies during the pandemic while being vigilant about the risk. They have worked closely with infection prevention societies and regulatory agencies to address this important human health concern · Stryker, a major manufacturer of endoscopes, has been closely monitoring the impact of COVID-19 since it was first reported, and they have taken action to ensure proper safety for their customers, employees, and communities This signifies that despite the pandemic situation, different strategic decisions made by these companies would make their business grow. CONCLUSION With the mystery around the disease remains unsolved at many levels, the management of healthcare becomes imperative. The safety of the people is paramount, and initiatives are being taken to get people through this unprecedented scenario. Though it is estimated that the pandemic will negatively affect the growth of the global juvenile polyposis treatment market, the strategic decisions made by different companies, governments, and other organizations will help out in handling this crisis eventually.
Why You Need A Niacinamide Serum? And How To Use It.
Niacinamide may not get as much attention as retinol and vitamin C, but it is a skincare powerhouse that deserves equal recognition. It is the definition of a multitasker, offering a host of distinct benefits that make it a good choice for a wide range of skin types and complexion issues. However, incorporating it into your current skincare routine might sound difficult. Is it OK to use niacinamide along with vitamin C and/or retinol? Is hyaluronic acid a viable alternative? We weigh in on everything you need to know about using niacinamide. What is niacinamide, exactly? Simply put, it's a B vitamin, one of two forms of vitamin B3, and it participates in a number of critical cellular operations in the skin. What benefits does it have for the skin? Buckle your seatbelts, because this is going to be a long list. Niacinamide is a fantastic treatment for acne-prone skin. Niacinamide reduces sebum production, which can help prevent acne and shine. The vitamin is also known for its anti-inflammatory qualities, which aid in the treatment of acne and other skin conditions such as eczema. Niacinamide helps to build the skin barrier, which is advantageous to people who have eczema or sensitive skin. It is also an efficient skin lightening agent, treating hyperpigmentation by blocking pigment transfer from pigment-producing cells known as melanocytes to skin cells on the surface where discoloration is visible. As if that wasn't enough, there's evidence that niacinamide can help to reduce wrinkling and photoaging by maintaining cell function and repairing DNA damage. To summarise, niacinamide has very few limitations. Is it OK to mix niacinamde and retinol? Yes! In fact, retinol and niacinamide are recommended together for faster effects. The soothing characteristics of niacinamide can also assist to alleviate the unpleasant side effects and irritation that usually accompany retinol's wrinkle-fighting effectiveness. Is it safe to combine with other ingredients? Yes, as a general rule, which is why it's found in many skincare products and is easy to incorporate into your present routine. Niacinamide is frequently coupled with salicylic acid, a beta-hydroxy acid typically found in acne products, due to its acne-fighting qualities. Combining niacinimadie's oil-removal properties with salicylic acid's ability to break down excess oil is an effective way to keep pores free and breakouts at bay. Niacinamide is an ideal choice for combining with alpha-hydroxy acids, which are chemical exfoliants that can cause skin irritation, due to its anti-inflammatory and skin barrier-strengthening effects. Because the AHAs exfoliate the dead skin cells that would otherwise make it impossible for the niacinamide to enter, combining them boosts the efficacy of the niacinamide. Finally, because niacinamide and hyaluronic acid can both help with dry skin, they are frequently mixed. What is the one thing that the jury is still out on? Vitamin C. Because vitamin C might inactivate niacinamide, the applications should be separated by 15 minutes. In truth, the two would have to be heated in order to interact negatively, and more and more cosmetics are combining the two in skin-brightening formulations. The bottom conclusion is that if you utilise a product that contains both vitamin C and niacinamide, it was most likely specifically designed to work together. If you're using two different products that include these chemicals, wait 15 minutes between applications or use one in the morning and the other in the evening. Should I use niacinamide? Sure, in a nutshell. One of the nicest aspects of niacinamide is not only the vast list of benefits it offers, but also how well it is tolerated, particularly by those with sensitive skin. This makes it an enticing choice for those whose skin is sensitive to more common acne or skin lightening agents like benzoyl peroxide or retinoids.