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Significant COVID-19 Impact on Non-Small Cell Lung Cancer Diagnostics in Healthcare Industry


The novel coronavirus has profoundly impacted all fields, including healthcare, medical device services, automotive, pharmaceutical and many others. This pandemic has led to shutdowns of mass production and disruptions in the supply chain that have impacted the economies of virtually every nation in the world. The pandemic also affected the non-small cell lung cancer diagnostic industry. The patient's fear of contracting the virus compels patients to stay home instead of undergoing diagnosis and treatment.
During the COVID-19 pandemic, countries worldwide witnessed a large number of patients suffering from COVID-19 and post COVID-19 complications such as cardiovascular disease, diabetes and kidney problems. As the COVID-19 cases were rising, the healthcare system had shifted its focus in curbing the disease, thereby delaying diagnosis and treatment of other chronic conditions as cancer. Thus, a negative impact is expected on the non-small cell lung cancer diagnostics market due to the pandemic scenario
As a result, the hospitals and clinics were filled up with COVID-19 patients and less preference was given to non-small cell lung cancer patients. Moreover, limited access to clinics, social distancing, the lockdown of the population, which results in a slow-down in patient flow and referrals, has also impacted the market growth.
However, with the cases decreasing in number and increase in vaccination against COVID-19 across the globe, the market for non-small cell lung cancer diagnostics market may get a boost due to some relaxation in COVID-19 cases, which will result in increased demand for non-small cell lung cancer diagnosis with patients coming forward to clinics and hospitals for treatment.

IMPACT ON DEMAND

Various screening, diagnostic and surgical procedures were restricted and at hospitals and cancer treatment centers, which resulted in disruptions in the non-small cell lung cancer diagnostics market. However, even during the pandemic, the lung cancer cases were subsequent, which is expected to increase the demand for non-small cell lung cancer diagnostics market.
For instance,
· According to World Health Organization (WHO), in 2020, lung cancer accounted for 2,206 771 deaths among both sexes. The lung cancer statistics include both small cell lung cancer and non-small cell lung cancer. About 13% of all lung cancers are small cell lung cancer and 84% are non-small cell lung cancer.
This proves an increase in the number of non-small cell lung cancer patients even during the COVID-19 pandemic. Moreover, according to the American Cancer Society, Inc., lung cancer patients are likely to get infected with coronavirus because of the changes in their immune system that control their body's defense systems.
For instance,
· According to a study published in PubMed, patients with lung cancer are at an increased risk of becoming infected with the virus and experience higher morbidity and mortality than the general population
Thus, having cancer such as non-small cell lung cancer may also increase the risk of severe illness from COVID-19 as the cancer therapy treatment reduce the immune system of the body. .
This has increased the demand for non-small cell lung cancer diagnostic tools, especially in cancer-dedicated hospitals and surgical centres, where all the patients of non-small cell lung cancer-related problems are treated. Thus, with the increased lung cancer cases, the demand for non-small cell lung cancer diagnostic will increase in the coming years.

IMPACT ON SUPPLY CHAIN

The supply chain was widely affected by the COVID-19 pandemic as acute restrictions and lockdowns produced many urgent situations in the early days of the pandemic, which needed immediate attention. The supply chain disruption has transformed many organizations' business environments, including the supply chain of non-small cell lung cancer diagnostics market. The supply chain disruption impacted the Asia-Pacific region initially, especially the demand from China due to challenges from restricted movement and quarantine period.
For instance,
· According to the FDA, 63 manufacturers representing 72 facilities in China that produce essential medical devices face obstacles in manufacturing medical devices and their supply, owing to citing workforce challenges and the necessary quarantine of workers. Moreover, closing borders of various countries is anticipated to diminish the supply chain business environment, as it may hamper export of the medical supplies
To minimize supply chain crises, the FDA has been firmly monitoring the supply chain with the assumption that the COVID-19 outbreak may adversely impact the supply chain of medical products, including shortages of critical medical products in the U.S. or potential disruptions in supply chains.
Many organizations and countries are looking forward to improving and diversified supply chain models in all aspects to manage such a crucial situation. A diversified supply chain model anticipated minimizing the export of medical products as well as increase end-to-end visibility.
For instance,
· The Brazilian government published a resolution eliminating import taxes on 141 medical products and hospital equipment
· The European Commission made a decision for helping Member States affected by the pandemic to suspend customs duties and VAT on medical devices temporarily
· Federal indirect tax body the Goods and Services Tax (GST) Council of India has decided to cut taxes on medical supplies

IMPACT ON PRICE

The coronavirus disease (COVID-19) pandemic does not significantly impact the global non-small cell lung cancer diagnostics market.
But it is estimated that if COVID-19 continues to spread for a prolonged period, then the demand for non-small cell lung cancer diagnostic equipment and devices will highly upsurge for top importer countries. For therapies and the diagnostic United States solicit the huge number of medical devices, followed by China and Japan.
For instance,
· According to the General Administration of Customs (GAC), China's exports of medical machinery and devices increased 40.5 percent in 2020 compared to the previous year, reaching USD 18.138 billion
· According to the World Trade Organisation, the U.S. imports and exports of medical goods increased by 16 %, reaching USD 1,139.00 billion in value
Henceforth for diagnosis, dependency of these countries highly increases on other exporters and many countries solely depend on China and the U.S. for the non-small cell lung cancer diagnostic equipment. Consequently, this may lead to a rise in the overall non-small cell lung cancer diagnostic cost.
This increase in the price of the non-small cell lung cancer diagnostic may hamper the market growth if it continues to be the same.
Additionally, if the lockdown continues to stretch for a long period, then import of non-small cell lung cancer diagnostics market is estimated to get more restricted, which may further lead to a rise in the price of the these devices

CONCLUSION

It is estimated that the COVID-19 pandemic outbreak has significantly impacted the growth of non-small cell lung cancer diagnostics market as the rising cases of COVID-19 worldwide the healthcare system had shifted its focus in curbing the disease, thereby resulting in the delay of diagnosis and treatment of non-small cell lung cancer. Thus, a negative impact is expected on the non-small cell lung cancer diagnostics market due to the pandemic scenario. However, with the increase in lung cancer patients worldwide, the demand for non-small cell lung cancer diagnostics will increase in the coming years. Moreover, poor lifestyle, smoking, alcohol consumption, lack of physical activity and other factors will contribute to the incidence of chronic disease such as lung cancer, including non-small cell lung, which is anticipated to increase the global non-small cell lung cancer diagnostics market in the coming years.
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Another impact of the COVID-19 pandemic is the delay in surgical and non-surgical procedures to treat selective diseases. Patients are preferring alternative treatment procedures that have no requirement for physically appearing in hospitals or clinics. Consequently, the demand for medical devices used to treat juvenile polyposis has decreased due to the decrease in various surgical and non-surgical procedures during the pandemic. For instance, · According to a study performed by BMJ Journals in the U.K., a weekly average of 35,478 endoscopic procedures were performed during the pre-COVID period. After the COVID-19 pandemic, these numbers reduced by 12 percent · According to an article by PMC, diagnosis of colorectal cancers was considerably delayed during the pandemic, which had a huge economic and workload burden on the gastroenterologists, surgeons, and oncologists Suppose the COVID-19 keeps on spreading like this for a long period. 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Consequently, the growth of the juvenile polyposis treatment market is anticipated to downgrade as this procedure needs the patient to be physically present. For instance, · According to CDC, in 2019, 43 percent of the health centers were capable of providing telehealth services, while in 2020, during the COVID-19 pandemic, it was reported that 95 percent of the health centers were providing telehealth services · According to May 2020 article published by PMC, COVID-19 had a huge impact on surgical practice. There was a huge decline in the number of surgical procedures taking place, and also the surgeons are recommending safe, non-surgical alternative options to treat their patients during the pandemic IMPACT ON SUPPLY CHAIN COVID-19 has led to a disruption in the supply chain of medical devices, which are essential for treating and diagnosing juvenile polyposis syndrome. In different countries, diagnoses of other diseases have slowed down due to increased pressure to diagnose COVID-19. This led to a significant delay in diagnosing juvenile polyposis syndrome, which ultimately reduced the number of treatment procedures. The COVID-19 pandemic has truly transformed some organizations' business environment; the organizations' supply chain has been hampered by several issues, including export and travel restrictions by some countries and lockdowns that have forced suppliers to shut down in the majority of the cases temporarily. For instance; · According to an article by The Hindu published in May 2021, China holds the majority of the market for raw materials, and unfortunately, the pandemic leads to global restriction along with series of lockdowns which leads to disrupted supply chain To minimize supply chain crises, healthcare organizations have been firmly monitoring the supply chain with the assumption that the COVID-19 outbreak may adversely impact the supply chain of a medical device or equipment. This includes shortages of endoscopes and colonoscopes required to treat juvenile polyposis or potential disruptions in its supply chains. To manage an adverse situation, many organizations have looked forward to improving and diversifying the supply chain model in all aspects. A diversified supply chain model anticipated minimizing the export of medical devices and equipment and increasing end-to-end visibility. The COVID-19 pandemic has shown various supply chain management methods, which may remain effective within a remote working environment. STRATEGIC DECISIONS FOR MANUFACTURERS COVID-19 can hamper the production and supply chain of endoscopes and colonoscopes, which are used in the treatment procedure of juvenile polyposis. Still, it also provides companies to improve their business by different means. Different companies made different strategic decisions to maintain their supply chain constantly and reduce the spread of the virus among their employees. They made proper decisions to maintain a safe work environment. For Instance, · Olympus, a leading manufacturer and supplier of endoscopes and colonoscopes, has maintained proper supplies during the pandemic while being vigilant about the risk. They have worked closely with infection prevention societies and regulatory agencies to address this important human health concern · Stryker, a major manufacturer of endoscopes, has been closely monitoring the impact of COVID-19 since it was first reported, and they have taken action to ensure proper safety for their customers, employees, and communities This signifies that despite the pandemic situation, different strategic decisions made by these companies would make their business grow. CONCLUSION With the mystery around the disease remains unsolved at many levels, the management of healthcare becomes imperative. The safety of the people is paramount, and initiatives are being taken to get people through this unprecedented scenario. Though it is estimated that the pandemic will negatively affect the growth of the global juvenile polyposis treatment market, the strategic decisions made by different companies, governments, and other organizations will help out in handling this crisis eventually.
Amazing Health Benefits of Manuka Honey
Manuka honey has had a large number of fans over the last few decades. People are not just excited by its rich taste but also about its health benefits. People love to slather onto their toast and mix it into their tea. But, do you know the varied benefits of Manuka honey? What is Manuka honey good for? It is believed that most types of honey possess some bacteria-killing process. This is because honey contains hydrogen peroxide, a compound that is highly used as an antiseptic. Manuka honey is used to soothe a sore throat, lessen inflammation and improve digestion issues. Honey has strong antiseptic, antimicrobial, antioxidant, anti-inflammatory properties. Here we will list the benefits of Manuka honey, which will help you before buying. 1. It is anti-bacterial Manuka honey has antibacterial properties due to Methylglyoxal (MG) and hydrogen peroxide in it. It has been proven for years to be a powerful weapon against illness-causing bacteria. Not only it kills bugs, but it provides moisture and nourishment. This is why honey has been used as a treatment for wounds and illnesses for centuries. Is Manuka honey also beneficial to you daily? Yes, it is. · You can use it as a treatment for keeping acne, burns and wounds clean and lubricated. · Flick a Manuka honey and tea tree formula on acne. · You can rub Manuka honey on cuts or skin infections. · You can use it to help kill mouth and throat infections. Manuka honey is sanctioned for clinical use in Australia as it has numerous advantages when it comes to dressing wounds. Applying honey on wounds aids to remove any diseased matter and clear the wound of dirt and debris. Also, the anti-inflammatory effects of Manuka honey lessen tissue swelling. Not only that, this honey seems to vitalize the immune system to regenerate tissue more quickly. This particular honey is used for healing burns because burn wounds heal faster if kept moist. Moreover, using honey on wounds means the bandage is less likely to stick to it, which means dressings are less painful to change and more gentle on regenerating tissues. With all these positive benefits, it can be an effective way to fix skin diseases. Manuka is undoubtedly quicker, easier and cheaper than any other remedy. Honey has been used as the best remedy to soothe sore throat and coughs for years. The honey creates a soothing layer on the throat which reduces irritation and kills bacteria at the same time. Many people use Manuka honey as a face mask to treat acne. The research shows that honey inhibits the growth of the bacteria that causes acne. 2. Using Manuka Honey for oral health You might find it odd, but it can fight oral bacteria to reduce plaque formation on the teeth. It is even being used to treat symptoms of gum disease like gingivitis. You might feel weird to think of something sweet being healthy for your gums and teeth. But research has shown that the antimicrobial properties of honey can fight against oral conditions. Keeping the gums and teeth healthy can aid you to have a healthy heart. It may sound strange, but that is the fact. If you are suffering from gingivitis, you may talk to your dentist before consuming Manuka honey as a natural remedy. Research has shown that the nasty bugs are killed by rubbing Manuka honey on damaged gum tissue, and the cells are stimulated to begin healing. 3. It supports healthy digestion Digestive issues are very common these days in our stressful and busy society. Weak digestion is one of the most heard issues among people these days. And if you do not have a healthy digestion system, you may feel uneasiness for the whole day. Well, it might sound weird, but Manuka honey can help. It has special enzymes that enter the gut and help to break down and digest food efficiently. Well, honey is pre-biotic, which means it provides food for those healthy, helpful bacteria we have living in our gut. To have a healthy digestive system, add Manuka honey to your favorite smoothies, tea, or you can have a teaspoon each morning before breakfast. Consuming honey with Luke warm water every morning helps you remain active all day and also helps you lose weight. 4. Manuka honey boosts your energy and support immunity While working a full day, you may feel like taking a nap at your desk, instead take a spoonful of Manuka honey. It can provide you with a hit of energy to keep you active to tackle the day. As honey contains healthy carbohydrates, natural sugars and nutrients, it helps you boost your energy level. It is known that some athletes choose Manuka honey to fuel themselves while workout or training sessions. If you don’t like taking it directly, you may prefer taking it in water. It is far healthier than taking energy drinks or any pre-workout drink. Moreover, Manuka honey contains a special compound that aids in increasing the production of the chemical called a cytokine, which sparks the production of the cell, which support and boost the immune system. 5. Helps prevent gastric ulcers As per research, it is found that when Manuka honey is consumed, it may slow down the growth of a type of bacteria that causes gastric ulcers. Its antioxidant properties may also help lessen inflammation in bowel diseases such as ulcerative colitis and irritable bowel syndrome. Is Manuka honey safe to use Manuka honey is safe to consume for most people, and you can consume 1 to 2 tablespoons every day to experience the reported benefits. Avoid consuming more than 2 tablespoons of Manuka honey a day, as it is high in sugar. If you are a diabetic patient or allergic to bees, you can consult your doctor before consuming Manuka honey. Make sure you should not give any honey to children under age 1. Where to buy Manuka honey? Are you wondering where you can buy the best quality Manuka honey? Don’t worry; with Ausvita Health here, you don’t need to seek anywhere else. You can find Manuka honey at a discounted price on Ausvita Health online. On Ausvita Health, you can also find various vitamins and beauty products to experience a healthy lifestyle.
Pharmaceutical Packaging Equipment Market worth $10.4 billion by 2025 - Exclusive Report by MarketsandMarkets™
According to the new market research report "Pharmaceutical Packaging Equipment Market by Product (Aseptic Packaging, Blister, Strip, Bottle, Tube, Carton, Case Packer, Wrapping Machine, Palletizing, Labeling & Serialization), Type (Tablet, Powder, Cream, Syrup, Aerosol), Region - Global Forecast to 2025", published by MarketsandMarkets™, the global Pharmaceutical Packaging Equipment Market size is projected to reach USD 10.4 billion by 2025 from USD 7.3 billion in 2020, at a CAGR of 7.4% from 2020 to 2025. Browse in-depth TOC on "Pharmaceutical Packaging Equipment Market" 276 – Tables 48 – Figures 330 – Pages Download PDF Brochure:-https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=19845828 The growth of the global pharmaceutical packaging equipment industry is driven by the rapidly growing generic and biopharmaceutical markets, growth in OTC drug sales, rising need for flexible and integrated packaging equipment, increased offshore manufacturing in the pharmaceuticals market, and the introduction of regulatory standards on packaging and stringent norms against counterfeiting. Primary packaging equipment accounted for the largest share in the market in the forecast period. On the basis of product, the pharmaceutical packaging equipment market is segmented into primary packaging equipment, secondary packaging equipment, and labeling and serialization equipment. In 2019, the primary packaging equipment segment accounted for the largest share of the market. The main function of primary packaging is to restrict climatic, chemical, or biological hazards that cause deterioration. The rising need for the aseptic filling and sealing of drug molecules into sterile containers and the increasing demand for parenteral vials and prefillable syringes are supporting the growth of this segment. Liquid packaging equipment expected to show the highest growth in the forecast period. Based on type, the pharmaceutical packaging equipment market is segmented into liquid, solid, semi-solid, and other packaging equipment. In 2019, the liquid packaging equipment segment accounted for the largest share of the market, followed by solid and semi-solid packaging equipment segments. The largest share can be attributed to the wide range of applications of liquid pharmaceutical dosage as they can be administered via either the oral or the parenteral route. Their palatability makes them a product of choice for geriatric and pediatric patients. Get 10% Customization on this Research Report :-https://www.marketsandmarkets.com/requestCustomizationNew.asp?id=19845828 Europe to hold the largest share in the global market during the forecast period of 2020–2025. Geographically, the pharmaceutical packaging equipment market is segmented into North America, Europe, the Asia Pacific, Latin America, and Middle East & Africa. Growth in the European market is driven majorly by the high pharmaceutical production, increasing demand for flexible packaging equipment by major pharmaceutical manufacturers, and the rising focus on product diversification by companies, driving the demand for innovative packaging equipment. Regulatory changes are also compelling pharmaceutical manufacturers to replace their older equipment with new equipment to adhere to the changing standards. The prominent players in this market are Syntegon Technology (Germany), IMA S.p.A. (Italy), Körber AG (Germany), Uhlmann Group (Germany), OPTIMA Packaging Group (Germany), Romaco Holding (Germany), Marchesini Group (Italy), ACG Worldwide (India), Coesia S.p.A. (Italy) and MULTIVAC Group (Germany).
Growing Support and Collaboration for Developing OTC Tests
 The growth of the OTC tests market is mainly driven by the rising prevalence of target diseases and disorders, such as diabetes and infectious diseases, both prominent ailments across the globe that require rapid and effective testing.  Growth in this market can be attributed to factors such as the increasing number of HIV-infected individuals across the globe, coupled with increasing availability and awareness about HIV OTC testing in emerging markets such as India, Brazil, and China.   The lateral flow assays segment is projected to grow at the highest rate in the market, by technology. In the past few years, the lateral flow assay POC testing market has grown significantly due to the increasing adoption of LFA testing products in-home care.   Download PDF Brochure @ https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=78819178 The Asia Pacific is estimated to grow at the highest CAGR during the forecast period. The high growth in this regional segment is majorly attributed to the increasing patient population base and the growing prevalence of infectious diseases.  Key market players The key players operating in the global Over The Counter/OTC test industry are OraSure Technologies (US), Roche Diagnostics (Switzerland), and i-Health Lab (US). A majority of the leading players in the market focus on both organic and inorganic growth strategies such as collaborations, partnerships, acquisitions, and agreements to maintain and enhance their market shares in the OTC tests market.  Research Developments: 1. In 2019, SD Biosensor launched STANDARD GlucoNavii GDH for blood glucose monitoring. 2. In 2019, LabStyle Innovations entered into an agreement with Better Living Now (BLN) for the distribution of its Blood Glucose Monitoring System and the DarioEngage digital health platform. 3. In 2018, DarioHealth partners with Byram Healthcare to further expand insurance health coverage for consumers in the US. 4. In 2016, Sinocare acquired PTS Diagnostics, to strengthen its product portfolio and accelerate future growth in the diagnostic testing market. 
Tissue Diagnostics Market: New Innovation, Future, and Trends
The rising incidence of cancer, developing infrastructure for cancer diagnosis, recommendation of cancer screening, availability of reimbursements, and increasing healthcare expenditure.  The consumables segment is expected to grow at the highest growth rate during the forecast period. This is attributed primarily to their requirement in large numbers, cost-effectiveness, and ease of use. The increasing number of reagent rental agreements is also one of the major factors to drive the growth of the consumables market globally.   The immunohistochemistry segment is estimated to register the highest CAGR during the forecast period. This can primarily be attributed to the increasing prevalence of chronic diseases across the globe, where this technology is mostly used in tissue diagnostics. Easy accessibility to advanced technologies, government initiatives for screening cancer patients, favorable reimbursement scenarios for pathology diagnostic tests, increasing healthcare expenditure, and high-quality infrastructure for hospitals and clinical laboratories in this region are the major factors driving the growth of the tissue diagnostic market in North America. Download PDF Brochure @ https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=1063949 Key Market Players The prominent players operating in the tissue diagnostic market include Roche (Switzerland), Danaher (US), Thermo Fisher Scientific (US), Abbott (US), Agilent Technologies (US), ABCAM (UK), Merck KGAA (Germany), BD (US), Hologic (US), Bio Rad (US), Biomeriux (France), Sakura Fientek Japan (Japan), BioSB (US), Biogenex (US), Cell Signaling Technology (US), Histoline Laboratories (Italy).   The research laboratories segment is expected to grow at the highest growth rate during the forecast period. This can be attributed to increasing outpatient surgeries such as endoscopies performed in ambulatory surgical centers (ASCs) and physician offices, which has increased the number of samples outsourced to clinical laboratories.   Research Developments Analysis 1. In 2019, Roche launched the VENTANA PD-L1 (SP142) Assay in CE (Conformité Européenne) markets. 2. In 2019, Hologic received CE approval for ThinPrep Genesis Processor. 3. In 2019, Roche entered into an agreement with GE Healthcare to develop an integrated digital diagnostics platform to improve oncology and critical care treatment.
Industry Trends, Growth and Analysis For Healthcare Fraud Analytics
Fraud analytics is the efficient use of data analytics and related business insights developed through statistical, quantitative, predictive, comparative, cognitive, and other emerging applied analytical models for detecting and preventing healthcare fraud. The global healthcare fraud analytics market is projected to reach USD 5.0 billion by 2026 from USD 1.5 billion in 2021, at a CAGR of 26.7% during the forecast period. Market growth can be attributed to a large number of fraudulent activities in healthcare, the increasing number of patients seeking health insurance, high returns on investment, and the rising number of pharmacy claims-related frauds. However, the dearth of skilled personnel is expected to restrain the growth of this market.  The global healthcare fraud analytics market is facing a plethora of challenges. Travel bans and quarantines, halt of indoor/outdoor activities, temporary shutdown of business operations, supply-demand fluctuations, stock market volatility, falling business assurance, and many uncertainties are somehow exerting a partial negative impact on the business dynamics.  Download PDF Brochure @ https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=221837663 The healthcare industry has been witnessing a number of cases of fraud, done by patients, doctors, physicians, and other medical specialists. Many healthcare providers and specialists have been observed to be engaged in fraudulent activities, for the sake of profit. In the healthcare sector, fraudulent activities done by patients include the fraudulent procurement of sickness certificates, prescription fraud, and evasion of medical charges.  A couple of reasons contributing to the growth of the health insurance market include the rise in the aging population, growth in healthcare expenditure, and increased burden of diseases. In the US, the number of citizens without health insurance has significantly decreased, from 48 million in 2010 to 28.6 million in 2016. In 2017, 12.2 million people signed up for or renewed their health insurance during the 2017 open enrollment period (Source: National Center for Health Statistics).  This growth is aided by the increasing affordability of health insurance for the middle class in this region and the rising awareness regarding the benefits of health insurance. In the UAE, as per a new regulatory policy (2017), any citizen residing and working in the UAE needs to be insured medically.   Major players in this market include IBM Corporation (US), Optum, Inc. (US), Cotiviti, Inc. (US), Change Healthcare (US), Fair Isaac Corporation (US), SAS Institute Inc. (US), EXLService Holdings, Inc. (US), Wipro Limited (India), Conduent, Incorporated (US), CGI Inc. (Canada), HCL Technologies Limited (India), Qlarant, Inc. (US), DXC Technology (US), Northrop Grumman Corporation (US), LexisNexis (US), Healthcare Fraud Shield (US), Sharecare, Inc. (US), FraudLens, Inc. (US), HMS Holding Corp. (US), Codoxo (US), H20.ai (US), Pondera Solutions, Inc. (US), FRISS (The Netherlands), Multiplan (US), FraudScope (US), and OSP Labs (US).  Research Developments Analysis 1. In January 2019, LexisNexis Risk Solutions collaborated with QuadraMed to enable patient identification capabilities and reduce the number of duplicate identities & fraudulent claims. 2. In August 2018, Verscend Technologies acquired Cotiviti Holdings. This acquisition helped improve the affordability of fraud detection solutions. 3. In June 2018, SAS Institute & Prime Therapeutics LLC teamed up, enabling Prime Therapeutics to utilize SAS’s analytic capabilities to combat the opioid crisis in the US
Cell-based Assays Market Expected to Reach $22.0 billion by 2025
The growing preference for cell-based assays in drug discovery, increasing funding for cell-based research, and growth in the number of drug discovery activities are the key factors supporting the growth of the market.   The cell-based assays market is projected to reach USD 22.0 billion by 2025 from USD 14.9 billion in 2020, at a CAGR of 8.1% during the forecast period. However, the growth of the market is likely to be restrained by factors such as the high cost of instruments, restrictions on reagent use, and the lack of infrastructure for cell-based research in emerging economies.  Due to the pandemic, companies have scaled up R&D efforts to develop a vaccine and drugs against the SARS-CoV-2 virus. Vaccine-related research activities in pharmaceutical & biotechnological companies, research centers, and academic research institutes are considered essential and have been largely unaffected in operations and output.  The players operating in the market are altering their long-term and short-term growth strategies by tapping into opportunities prevalent in the research market by developing innovative products to combat the pandemic. The increased demand for research on COVID-19 has created a large scope for cell-based 45 assays in viral infection research, vaccine development, and overall drug discovery for both researchers and laboratories.  Download PDF Brochure @ https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=119917269 Cell-based assays are employed to shorten the time and increase the throughput needed for these assays. This has significantly increased the demand for cell-based assays to provide an early indication of the toxicity characteristics of the drug candidates.  Cell-based assays are key components in the drug development process. Cell-based assays have several advantages over in vitro biochemical assays. They offer consistent tissue-specific responses in a biologically relevant microenvironment as opposed to biochemical assays.  It is also not possible to prepare or purify every target for biochemical measurement, which is a major factor limiting the applications of biochemical assays. As a result, pharmaceutical & biotechnology companies as well as CROs are replacing biochemical assays with cell-based assays for their lead identification and optimization processes in drug discovery.  The prominent players operating in the cell-based assays market are Danaher Corporation (US), Thermo Fisher Scientific (US), Merck KGaA (Germany), Becton, Dickinson and Company (US).  Research Developments Analysis 1. In 2020, Danaher Corporation (US) launched ImageXpress Micro-confocal High-content Imaging System. 2. In 2020, Thermo Fisher Scientific (US) acquired Phitonex, Inc. (US). The acquisition of spectral dye platform manufacturer Phitonex will enable Thermo Fisher to offer greater flow cytometry and imaging multiplexing capabilities in protein and cell analysis research. 3. In 2020, Charles River Laboratories entered into a multi-year drug discovery collaboration with Karuna Therapeutics, a US-based CRO, to expand its drug discovery capabilities. 4. In 2020, Danaher Corporation completed the acquisition of GE Healthcare’s biopharma business and was renamed as Cytiva. 5. In 2018, Lonza Group AG (Switzerland) established its Collaborative Innovation Center in the new Life Science Park on the outskirts of Haifa, Israel. This center focuses on the R&D projects of Lonza’s Pharma Biotech & Nutrition segment.
Pyrogen Testing Market worth $1,689 million by 2025
According to the new market research report "Pyrogen Testing Market by Product & Service (Assays, Kits, Reagents, Instruments, Services), Test Type (LAL, Chromogenic, Turbidimetric, Gel Clot, In Vitro, Rabbit), End User (Pharmaceutical, Biotechnology, Medical Device), Region - Global Forecast to 2025", published by MarketsandMarkets™, the Pyrogen Testing Market is projected to reach USD 1,689 million by 2025 from USD 927 million in 2020, at a 12.7% CAGR. Browse in-depth TOC on "Pyrogen Testing Market" 107 – Tables 36 – Figures 170 – Pages Download PDF Brochure: https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=255266155 The growing awareness of food safety mainly drives growth in the market, rising incidence of infectious diseases, increasing pandemics frequency, increasing R&D in the pharmaceutical and biotechnology industries, and growing focus on personalized medicine. Emerging economies such as China and Japan are providing lucrative opportunities for the players operating in the market. The assays, kits, & reagents segment accounted for the largest share of the pyrogen testing market, by product & service segment, in 2019 Based on product & service, the market is segmented into assays, kits, and reagents; instruments; and services. The assays, kits, & reagents segment accounted for the largest share of the market in 2019. The frequent requirement of assays, kits, and reagents in large numbers compared to instruments and the rising preference for kit-based testing are the major factors driving this segments growth. LAL tests segment to register the highest growth rate during the forecast period The pyrogen testing market is segmented into LAL tests, in vitro tests, and rabbit tests based on test type. In 2019, the LAL tests segment accounted for the highest growth rate. This can be attributed to the rising need for innovative laboratory testing procedures and the increasing support for vaccine development. The pharmaceutical & biotechnology companies segment accounted for the largest share of the pyrogen testing market, by end user segment, in 2019 Based on end-users, the market is segmented into pharmaceutical & biotechnology companies, medical device companies, and other end users. In 2019, pharmaceutical & biotechnology companies accounted for the largest share of the market. High inclination towards outsourcing preclinical, clinical, and laboratory testing services, a large number of ongoing drug discovery activities, and the increasing number of R&D facilities globally are the major factors driving this segments growth. Get 10% Customization on this Research Report: https://www.marketsandmarkets.com/requestCustomizationNew.asp?id=255266155 North America is the largest regional market for pyrogen testing market The market is segmented into five regions, namely, North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. In 2019, North America accounted for the largest share of the market. The large share of this region can be attributed to the rising prevalence of diseases, a growing number of drug approvals, increasing pharmaceutical drug pipelines, and growing consumer awareness about product safety. The major players operating in this pyrogen testing market are Charles River Laboratories, Inc. (US), Lonza (Switzerland), Merck KGaA (Germany), Thermo Fisher Scientific, Inc. (US), Associates of Cape Cod, Inc. (US), GenScript Biotech Corporation (China), bioMérieux SA (France), FUJIFILM Wako Pure Chemical Corporation (Japan), Eurofins Scientific (Luxembourg), WuXi AppTec (China), Hycult Biotech (Netherlands), Ellab A/S (Denmark), Microcoat Biotechnologie GmbH (Germany), InvivoGen (US), Nelson Laboratories, LLC (US), Almac Group (UK), Pacific Biolabs (US), STERIS plc (US), Accugen Laboratories, Inc. (US), TOXIKON (US), Minerva Analytix GmbH (Germany), Indoor Biotechnologies, Inc. (US), Creative Bioarray (US), Lucideon Limited (UK), and North American Science Associates, Inc. (US). Browse Related Reports: In Vitro Toxicity Testing Market by Product (Assay (Western Blot, Tissue Culture),Equipment, Assay Reagent, Software), Toxicity Endpoints (ADME, Skin Irritation, Corrosion),Industry (Pharmaceutical, Cosmetics)-COVID-19 Impact - Global Forecast to 2025 https://www.marketsandmarkets.com/Market-Reports/in-vitro-toxicology-testing-market-209577065.html In Vitro Diagnostics Market by Product (Instruments, Reagents), Technology (Immunoassay, Clinical Chemistry, Molecular Diagnostics, Hematology, Urinalysis), Application (Diabetes, Oncology, Cardiology, Nephrology) - Forecast to 2023 https://www.marketsandmarkets.com/Market-Reports/ivd-in-vitro-diagnostics-market-703.html
The Future of Cell & Gene Therapy Manufacturing Services Market
Growth in the cell & gene therapy manufacturing services market is primarily driven by the high incidence of cancer and other target diseases, increasing investments in pharmaceutical R&D, investments in advanced technologies by CDMOs, and increasing partnerships & agreements between pharmaceutical companies and CDMOs. However, the high operational costs associated with cell & gene therapy manufacturing are expected to restrain the growth of the cell & gene therapy manufacturing services market to a certain extent.  The pandemic slowed the economic growth of various countries, including the US, Germany, the UK, India, and China. It also resulted in control measures that impacted operations in life science organizations, such as production and research.    The impact varied due to changes in COVID-19 case volumes throughout the year, but the worst effect was seen in April 2020. Trials involving respiratory disease, oncology, ID/anti-infectives, and cardiovascular disease were the worst-hit during this time.  Most pharmaceutical companies continue to invest heavily in the development of novel drugs and devices. The pharmaceutical industry, in particular, is R&D-intensive. Pharmaceutical companies invest in R&D to deliver high-quality and innovative products to the market.  For More Information Download PDF Brochure @ https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=180609441 With the impact of COVID-19, the global pharma R&D growth rate has dropped to 0.3% from 2019–2020. As per report findings, this R&D spend is expected to grow steadily between 2019 and 2026 at a CAGR of 3.2% to reach USD 232.5 billion, slower than the historical CAGR of 4.6% between 2012 and 2019. The increase in pharmaceutical R&D has resulted in a sharp increase in the number of cell & gene therapy candidates under development. This has made it necessary to outsource manufacturing services to develop cost-effective and efficient cell & gene therapies.  Currently, there are 1,200 cell & gene therapies in trials worldwide. There are more than 700 investigational cell & gene therapies in clinical development in the US alone. However, manufacturing facilities have not kept up. It has been estimated that hundreds of facilities will be needed to manufacture the treatments that are now in clinical trials.  Key Market Players Key players in the cell & gene therapy manufacturing services market include Thermo Fisher Scientific (US), Merck KGaA (Germany), Charles River Laboratories (US), Lonza (Switzerland), Catalent (US), WuXi AppTec (China), Takara Bio Inc. (Japan), Nikon Corporation (Japan), FUJIFILM Holdings Corporation (Japan), F. Hoffmann-La Roche Ltd. (Switzerland), Oxford Biomedica plc (UK), and Cell and Gene Therapy Catapult (UK).  Research Developments Analysis : 1. In 2021, Charles River Laboratories acquired a cell & gene therapy CDMO—Cognate BioServices—to increase its cell and gene therapy manufacturing capabilities. 2. In 2021, Thermo Fisher Scientific acquired Henogen S.A., Novasep's viral vector manufacturing business in Belgium, for approximately USD 859.7 million. This acquisition will increase its presence in the cell & gene therapy manufacturing therapy market. 3. In 2019, Thermo Fisher Scientific acquired Brammer Bio, a company engaged in viral vector manufacturing for gene and cell therapies, for USD 1.7 billion.
Oxygen cylinder vs oxygen concentrator
In case you have been pondering the possibility of acquiring an oxygen concentrator at home, there are several benefits that you should know about. O2 nasal cannula treatment is a common treatment for people with COPD, congestive heart failure, or other state-of-the-art respiratory conditions. Just when a constant illness disables the limit of the lungs, it is mandatory to pass a kind of cleaner breathable air. The highest convergences of oxygen are transported by a nasal cannula or a shroud. When you get the rental and purchase oxygen concentrator, it can commonly go by around five or six LPM. And the flow rate of the O2 machine is quite continuous and can help in the recovery of the patient. O2 cylinders have been around for quite some time and can provide increased flow rates for patients who need to wear a cover, although the cylinder must be continually replaced with another. Patients who need help breathing throughout the day can go through a couple of cylinders each week, and transporting cylinders is really difficult. A home oxygen concentrator, in any case, uses the air in the room and thus does not need another concentrator supplement. Any other reason why you should avoid using oxygen cylinders : Reliable supply - People who get their pure breathing air from the room are less subject to recharge load. but at one point the oxygen cylinder took advantage of the power outage. When the power outage occurs, the only portable oxygen concentrator can work, but the non-portable oxygen machine cannot work without electricity. so at that moment only the cylinder works. Easy transportation -  If we compare the transportation of the oxygen machine and the oxygen cylinder, the transportation of the oxygen machine is easy compared to the cylinder. Because when you leave home, the cylinder is not easy to carry in the car and other vehicle, but the portable oxygen concentrator is only made for travel. Safety Purpose - A leak in the metal frame of the gas cylinder can cause a room with a lot of O2, increasing the risk of fire. Filled compartments are not safe in view of the measurement of the pressure factor inside. In the event that the neck of the cylinder holder breaks or becomes wet from a fall or other effect, the gas canister could turn into a shot, similar to a torpedo or rocket. Erratic directions of cracked gas compartments can cause extreme injury. A home oxygen concentrator does not develop pressure or have a similar potential to become a hazard. From lgrespicare
Why You Need A Niacinamide Serum? And How To Use It.
Niacinamide may not get as much attention as retinol and vitamin C, but it is a skincare powerhouse that deserves equal recognition. It is the definition of a multitasker, offering a host of distinct benefits that make it a good choice for a wide range of skin types and complexion issues. However, incorporating it into your current skincare routine might sound difficult. Is it OK to use niacinamide along with vitamin C and/or retinol? Is hyaluronic acid a viable alternative? We weigh in on everything you need to know about using niacinamide. What is niacinamide, exactly? Simply put, it's a B vitamin, one of two forms of vitamin B3, and it participates in a number of critical cellular operations in the skin. What benefits does it have for the skin? Buckle your seatbelts, because this is going to be a long list. Niacinamide is a fantastic treatment for acne-prone skin. Niacinamide reduces sebum production, which can help prevent acne and shine. The vitamin is also known for its anti-inflammatory qualities, which aid in the treatment of acne and other skin conditions such as eczema. Niacinamide helps to build the skin barrier, which is advantageous to people who have eczema or sensitive skin. It is also an efficient skin lightening agent, treating hyperpigmentation by blocking pigment transfer from pigment-producing cells known as melanocytes to skin cells on the surface where discoloration is visible. As if that wasn't enough, there's evidence that niacinamide can help to reduce wrinkling and photoaging by maintaining cell function and repairing DNA damage. To summarise, niacinamide has very few limitations. Is it OK to mix niacinamde and retinol? Yes! In fact, retinol and niacinamide are recommended together for faster effects. The soothing characteristics of niacinamide can also assist to alleviate the unpleasant side effects and irritation that usually accompany retinol's wrinkle-fighting effectiveness. Is it safe to combine with other ingredients? Yes, as a general rule, which is why it's found in many skincare products and is easy to incorporate into your present routine. Niacinamide is frequently coupled with salicylic acid, a beta-hydroxy acid typically found in acne products, due to its acne-fighting qualities. Combining niacinimadie's oil-removal properties with salicylic acid's ability to break down excess oil is an effective way to keep pores free and breakouts at bay. Niacinamide is an ideal choice for combining with alpha-hydroxy acids, which are chemical exfoliants that can cause skin irritation, due to its anti-inflammatory and skin barrier-strengthening effects. Because the AHAs exfoliate the dead skin cells that would otherwise make it impossible for the niacinamide to enter, combining them boosts the efficacy of the niacinamide. Finally, because niacinamide and hyaluronic acid can both help with dry skin, they are frequently mixed. What is the one thing that the jury is still out on? Vitamin C. Because vitamin C might inactivate niacinamide, the applications should be separated by 15 minutes. In truth, the two would have to be heated in order to interact negatively, and more and more cosmetics are combining the two in skin-brightening formulations. The bottom conclusion is that if you utilise a product that contains both vitamin C and niacinamide, it was most likely specifically designed to work together. If you're using two different products that include these chemicals, wait 15 minutes between applications or use one in the morning and the other in the evening. Should I use niacinamide? Sure, in a nutshell. One of the nicest aspects of niacinamide is not only the vast list of benefits it offers, but also how well it is tolerated, particularly by those with sensitive skin. This makes it an enticing choice for those whose skin is sensitive to more common acne or skin lightening agents like benzoyl peroxide or retinoids.