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How COVID-19 Impacted on Niemann-Pick Disease in Healthcare Industry ?

COVID-19 Impact on Niemann-Pick Disease in Healthcare Industry

OVERVIEW

A novel coronavirus, SARS-CoV-2, appeared in December 2019 in Wuhan, China, spreading much faster than its predecessors and has already infected millions of patients worldwide as of April 19, 2020. As the scope of the current COVID-19 outbreak has reached the proportion of pandemics, significant international efforts in public health are underway to control the epidemic. The covid-19 pandemic majorly impacted the rare diseases patients because, during the pandemic, the need to provide high-level care for a large number of patients with COVID-19 has affected resourcing and limited the routine maintenance of all other conditions. The impact of health emergencies particularly faced by the rare disease communities, organizations, clinics, and other healthcare providers. The health economic challenges faced by patients and their families, institutions, research organizations, and healthcare providers during the pandemic outbreak have demonstrated the importance of ensuring continuity of care in the management of rare diseases, including adequate diagnostics and monitoring protocols, and highlighted the need for a structured emergency strategy.
Niemann-Pick disease is a rare, inherited disease that affects majorly body's ability to metabolize fats such as cholesterol and lipids within the cells. Over time, these cells got malfunctioned and died. The disease can affects the brain, spleen, nerves and, if get severe, may affect lungs, bone marrow, and other organs. The disease can occur at any age but majorly affects children. There is no known cure for the disease, and sometimes it may be fatal for children, the only treatment is focused on helping people live with their symptoms.

IMPACT ON PRICE

Various market players are facing a large number of challenges due to the coming of the novel coronavirus and different strains; one such issue is the uncertainty surrounding the impact of covid-19 on off label drugs demands. Due to the increased coronavirus cases and continuous lockdown, the costs of the drugs and their APIs increase automatically. On the one side, it will increase the revenue of the companies, but a patient may resist buying the products, which ultimately increases the stress level on the patients.
Moreover, Due to the pandemic, there is the delay associated with various types of limitations faced by the manufacturers to fulfill the end product order, which has resulted in the less availability of medical devices in the market and due to which the cost of available devices has increased with the several factors. Also, due to the Coronavirus disease (COVID-19) pandemic outbreak, manufacturers are forced to find new contract manufacturers and suppliers for more manufacturing activities to different or unique facilities location that are less impacted by the outbreak.
The impact of Covid-19 has created huge price impact on the government as well as on patient families that they have to buy the drugs on higher rate as compared to the average rate.

IMPACT ON DEMAND

The Coronavirus zone is the result of various markets around the world. This is the cause of the widespread closures and isolation that are affecting world economic activity. As the cases increases in the month of April 2020, the sudden surge in demand has seen, and drugs and medical devices went out of stock.
Moreover, the decrease in the revenue of the key market players depicted in their quarterly results, such as Medtronic, among others, gave the evidence of decline in the demand for medical devices due to the emergence of the COVID-19 pandemic.
For instance,
· Medtronic reported a decline of 1% in its brain therapies net sales of the financial results of 2020 as compared to 2019. The reduction was primarily motivated by the detrimental effects of the COVID-19 pandemic and the subsequent deferral to companies of medical procedures.
· Impact on rare disease organization also faced significant fundraising income loss, this consequential income loss may leads to loss of various people jobs associated with the organizations. The cutting or income loss leads to the reducing staff, canceling offices leases, and delay or cutting office programs.
The impact of covid-19 majorly impacted the organizations if the revenues loss projections do not change, this will leads to temporarily or permanently shut down of small and middle foundations and organizations.

IMPACT ON SUPPLY

As the epidemic intensifies, supply chains can be at significant risk due to over-located locations that can potentially be disrupted. The supply chain of drugs, devices, and services has been disrupted. The spread of COVID-19 makes it difficult for governments to use these drugs; the availability of these systems faces constant challenges due to their components of use and limited initial needs. Moreover, as there is no cure for the disease, only physical activities/therapies may suppress the symptoms also affected by pandemics.
According to the NORD (National Organization for Rare Disorders), in the U.S. stated that 74% of the population have had canceled medical appointments due to Covid-19 pandemic, 69% of population concerned about their medication and medical supplies.
For instance,
• In June, ResMed stated that, due to the Covid-19 pandemic company sleep apnea business segment adversely affected including sleep clinics, physician practices, HME suppliers. As new patients are prescribed sleep apnea devices such as PAP, CPAP devices for the treatment through hospitals that are directing their resources to critical care, including COVID-19 treatment. The covid 19 impacts may continue to decrease demand for the sleep apnea devices sale

STRATEGIC DECISIONS OF GOVERNMENT AND MANUFACTURERS

As such, market participants are involved in the production of drugs, expanding their business through a variety of programs, including collaboration, contracts, and pipeline development, collaboration, and market expansion. It is expected that the strategic decisions of these companies will provide significant opportunities for market participants operating in the Niemann-Pick Disease market.
For instance,
· In July 2020, Abbott announced that it had received FDA approval for the use of the Patient Controller App on compatible personal Apple smartphone devices. The approval will allow the patient living with neurological conditions to manage their therapy directly from personal smartphone.
· In May 2020, Philips, a global leader in health technology, joined forces with the American Telemedicine Association (ATA) to help further the adoption of telehealth across the industry, demonstrating its commitment to connecting care across acute, post-acute, and home care settings. The continued collaboration spotlights telehealth's growing adoption and momentum amidst COVID-19 and the need to convey the exponential shift to telehealth capabilities.
· In U.S., NIH supports the research survey of “CURE EPILEPSY ORGANIZATION” to examine the impact of Covid-19 on Rare Disease Community. The survey includes more than 200 rare diseases including the brain, immune system disorders, heart, lungs, brain development diseases, and more.

CONCLUSION

As this pandemic situation has resulted in many restrictions in different places around the world, still the market players of dealing in rare diseases therapy and services were able to manage their service stock. Different companies dealing in metabolic diseases therapy services were finding out their own way to deal with this pandemic situation. The government and companies around the globe are working together and have issued advice for those undergoing therapies centers during these unprecedented times during COVID 19 lockdown around the world.
The supply chain was destroyed, but several steps were taken by the government and companies, which will help them, get their needed output for therapy service. By increasing the material price, the companies can maintain their overall revenue.
Thus, different foundations, organizations,, and services center markets are finding ways to deal with this pandemic situation.
Figure 1: Relationship between Coronavirus and Lysosome storage diseases : Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway
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These health benefits include eliminating itchiness, improving circulation, and decreasing skin moisture. Sponge baths have been used for years and have proven results. If you haven’t tried one yet, do it soon. Luckily, there is a company called, From the Heart to Home Services that provides assisted living facilities and providing a safe and caring atmosphere in which your loved one can receive the absolute best care possible. By working with an experienced and reputable company that offers the right amount of care at a price you can afford, your loved one will be able to live a healthy and happy life without needing to worry about the costs or how they will get the best treatment for themselves.
pregnancy after an abortion( MTP kit ) BLACK-FRIDAY-DEALS are ONN Hurry!up
Introduction I know that you have a lot of questions about getting pregnant after abortion, but I'm going to try and answer them as best as possible. Cheap MTP Kit has two dynamic fixings Mifepristone and Misoprostol are utilized either together or alone. Mifepristone is a progesterone inhibitor and Misoprostol is a prostaglandin. They both work in different ways to induce abortion, though they're often used together. The first thing to remember about the Cheap MTP Kit is that it has two dynamic fixings Mifepristone and Misoprostol are utilized either together or alone. The second thing to know is that while these medications are safe, they may not always be effective at preventing pregnancy after an abortion. Where to Buy Abortion Pills? There are many online abortion clinics that provide safe and effective abortions. You can easily find out if a particular clinic is reliable by looking at its reviews on various websites such as Google or Yelp. It's also important for you to make sure that the person who will be assisting you during your abortion has had experience working with women who have already undergone this procedure before so they know what questions you might have after your procedure is over, how much time it will take (which depends on how far along in your pregnancy), etc., If possible try contacting several different clinics until one agrees to give you their services without charging anything up front because nobody wants surprises when everything goes wrong! Can you get pregnant after an abortion? You can be pregnant after an abortion. And, yes, it's possible to get pregnant after a miscarriage or abortion. However, you can't get pregnant from your period and it's not possible for you to contract an STD (sexually transmitted disease) from the procedure alone. In fact, there are no diseases that are spread through pregnancy or childbirth; they're spread by sexual contact with someone who has them in their bloodstreams at the time of sex. What is the effect of Cheap MTP Kit on the body? MTP Kit is a safe and secure technique to get rid of the fetus. It is not a surgical procedure, but it requires you to take some pills or shots. The process of using MTP Kit involves: ● Taking one pill about 6-12 hours before having sex ● Taking another pill about 24 hours after having sex (it's important that you don't conceive from this) The effects of using MTP kits can last for up to 12 months if used properly, which means you will need to repeat the process again once your period resumes if it does not come back within 4 weeks. How does Cheap MTP Kit give Abortion? MTP Kit is a combination of two medications Mifepristone and Misoprostol. The first, mifepristone (Mifeprex), blocks the hormone progesterone in the body, which is essential for pregnancy. The second drug, misoprostol (Cytotec), causes uterine contractions that bring on labor. How to use MTP Kit? ● You should use MTP Kit as per the doctor's directions. ● You can get MTP Kit from a pharmacy or through a doctor. ● A doctor will tell you how to use MTP Kit and when to take it. ● The cost of using MTP Kit is affordable and reliable, too! So, this is all about what we have for you for today. Cheap MTP Kit is a safe and effective way to end unwanted pregnancy. It can be used for both early and late abortions, with the same drug being given twice. Once you have taken it, you will need to follow up with another dose of misoprostol (also known as Cytotec) within 72 hours of taking MTP Kit so that your body has time to expel the embryo/fetus from your uterus. Mifepristone was originally developed by French pharmaceutical company Roussel Uclaf in 1960s but was only approved by US federal regulators in 2000 after years of trials and testing on animals; it is now available over-the-counter without a prescription at many pharmacies around the country since it came off patent protection in 2007! Conclusion In conclusion, getting pregnant after an abortion is not an easy task. It will take some time for you to conceive and if want to get pregnant straight away then it would be best if you don’t go through with the termination procedure. If you do go through with the procedure then there are many risks involved in pregnancy such as high chances of miscarriage and premature birth
Cheap MTP Kit: Safe pregnancy termination | Patient Education
Looking to buy Cheap MTP Kit(Unwanted Kit Online) online in USA, Australia, and UK with non-prescription at low cost ? LocalMedStore is one of the top-rated online pharmacy in USA, and Australia to buy Cheap MTP Kit without prescription and get doorstep delivery without any hassle. If you're pregnant, it's important to decide whether or not to continue the pregnancy. You may want an abortion (Cheap MTP Kit) if you or your partner can't afford a child or if you don't feel ready to be a parent. (For more information on abortion, see our article What is an abortion?) In this article, we'll explain: You and your partner should talk about the advantages and disadvantages of having an abortion (Cheap MTP Kit Talking about the decision will help you deal with any stress or anxiety that may arise from it, as well as give you time to think about what is best for both of you. Talking to someone else can also help put your mind at ease; for example, if there's someone else in your life who has had children or who has been through a similar situation, he or she might be able to offer advice that helps relieve some of the pressure from thinking about making this important decision alone. There are several options for ending a pregnancy. There are several options for ending a pregnancy. The most common type is called an abortion, which is performed by a doctor or nurse at a medical facility. This procedure can be done either by inserting a suction device into the uterus (womb) to remove the embryo or fetus, or by injecting medication (Cheap MTP kit) that causes contractions that cause fetal death. It’s important to remember that there is no need to feel ashamed if you choose this option—it’s your right as a woman! The type of abortion you can have depends on how far along you are in your pregnancy. The type of abortion (Cheap MTP Kit) you can have depends on how far along you are in your pregnancy. If you are less than 10 weeks pregnant, you can have an aspiration abortion. An aspiration procedure involves removing some or all of the fetus (the baby) without using forceps to remove it from the uterus. The reason why this is done is because there is a chance that a suction device might puncture or tear open the uterine wall during delivery, which could cause infection and hemorrhage as well as other problems for mother and child alike; however, this risk is small compared to risks associated with surgical procedures like dilation & Curettage (D&C). If you are less than 10 weeks pregnant, you can have an aspiration abortion. An aspiration abortion is a procedure that uses suction to remove the contents of your uterus. You will be given anesthesia during this process, which involves inserting a long needle into your vagina and cervix (the opening to your uterus). The doctor will then use a syringe to collect the pregnancy tissue from inside your uterus. If you are less than 10 weeks pregnant, you can have an aspiration abortion using local anesthesia instead of general anesthesia. This means that only enough medication is needed to numb the area around where this procedure will take place so that it doesn't hurt as much when done correctly by an experienced doctor or nurse practitioner who knows how best make sure everything goes smoothly without causing any additional pain or discomfort afterwards compared with general anesthesia methods used elsewhere If you are more than 10 weeks pregnant, you probably will not be able to have an aspiration abortion. An aspiration abortion (Cheap MTP Kit) is a procedure in which a doctor uses a suction tube inserted into your vagina and forcefully pulls out the fetus from inside your uterus using the same suction mechanism that makes vacuum cleaners work. This can be done up to about 20 weeks of gestation (the equivalent of 9 months). At 12 to 24 weeks, you can have a dilation and evacuation (D&E) procedure. D&E is a surgical procedure that involves removing the fetus from the uterus. It's used for abortions (Cheap MTP Kit) after 12 weeks of pregnancy, or 24 weeks of pregnancy if you're past a gestational limit specified by your healthcare provider (like 15 or 18 weeks). The most common method of administering anesthesia during an abortion procedure is called suction aspiration—the doctor uses suction cups on a plastic tube to suck out some tissue inside your womb. This can happen either vaginally or through an abdominal incision (a cut in your belly) made by using forceps or scissors to grab what they need to remove with their hands. Most women who have abortions do not regret their decision later in life. Most women who have an abortion do not regret their decision later in life. In fact, most feel relief and satisfaction with the experience. In addition to this, most women report that having an abortion was the right decision for them at the time it occurred. It's OK to change your mind after an abortion has started, but doctors can't always stop it once it has begun. Once an abortion (Cheap MTP Kit) has begun, it's unlikely that doctors can stop it. If you change your mind and want to stop the procedure, tell the doctor immediately. If you do so after the abortion has already begun, there may be a chance that more invasive procedures will be needed to complete this process. Conclusion If you are one of the millions of women who have had an abortion, it's important to remember that abortion is a very personal decision. There is no right or wrong answer, and everyone's situation is unique. It's also important to understand that if you choose not to proceed with an aspiration abortion or D&E procedure, your health care provider can still help you terminate your pregnancy in other ways.
HOW TO GET RID OF A COLD SORE VERY FAST!
Want to know how to get rid of a cold sore very fast? Then you are at the right place. Cold sores are small, painful blisters that typically form on the lips, chin, cheeks, or nose.  They’re caused by the herpes simplex virus and usually go away on their own within two to four weeks.  But, if you’re looking for a way to get rid of a cold sore very fast, there are a few things you can do. TABLE OF CONTENTS What are cold sores? Causes: What causes cold sores? Prevention: How can you prevent cold sores? Treatments: What treatments are available for cold sores? Remedies: Home remedies for cold sores When to see a doctor for a cold sore Conclusion WHAT ARE COLD SORES? Cold sores, also known as fever blisters, are small, fluid-filled blisters that develop on the lips, mouth, throat, cheek, or nose.  These sores are usually caused by the herpes simplex virus-1 (HSV-1), which is the same virus that causes genital herpes.  Cold sores are highly contagious and can be passed from person to person through close contact, such as kissing or sharing eating utensils, or coming into contact with the fluid from a cold sore.  There is no cure for cold sores, but they can be treated with antiviral medications. Cold sores usually go away on their own within 2-3 weeks.  Symptoms include redness, swelling, and blisters. Treatment focuses on relieving symptoms and can include over-the-counter medicines. CAUSES: WHAT CAUSES COLD SORES? Cold sores are a common viral infection. Cold sores are a common affliction that usually affects the mouth area.  There are many different types of cold sores, but they all have one thing in common: they’re caused by the herpes simplex virus (HSV) and can be quite painful.  HSV is a highly contagious virus that can be spread through direct contact with an infected person, or by sharing items like lip balm or towels. Once you’re infected with HSV, the virus stays in your body for life.  Cold sores usually occur on the lips, nose, or chin. They can also occur on the cheeks or fingers.  In fact, cold sores are contagious and can be spread through kissing or sharing cups and utensils. There are many things that can trigger a cold sore, such as stress, fatigue, or even exposure to sunlight.  While there is no cure for cold sores, there are many ways to treat them and make the symptoms more bearable. PREVENTION: HOW CAN YOU PREVENT COLD SORES? Most people have been affected by cold sores at some point in their lives. If you have ever had a cold sore, you know they are no fun.  Cold sores are small, painful blisters that usually show up on your lips or around your mouth. These painful blisters can be a real nuisance, but there are ways to prevent them.  Cold sores are caused by the herpes simplex virus, and they are most commonly spread through skin-to-skin contact or sharing utensils or other items with someone who is infected.  There is no cure for cold sores, but there are things you can do to prevent them. These are some steps to prevent cold sores. Avoid triggers. Keep lips moisturized. Use lip balm or cream. Come on, let's dive into it.
A Brief On Healthcare Integration System
A Healthcare integration system is a healthcare software that allows different healthcare organizations to work together to improve patient care. The healthcare integration system features include: 1. Healthcare data exchange: The healthcare data exchange allows different healthcare organizations to share patient medical records. 2. Healthcare information sharing: Healthcare information sharing allows different healthcare organizations to share patient information. 3. Healthcare security: Healthcare security allows different healthcare organizations to protect patient information. The healthcare integration system features allow different healthcare organizations to improve patient care. When it comes to healthcare app development, healthcare integration is a key feature to consider. Healthcare integration allows for the sharing of data and information between different healthcare apps and systems. This sharing of data and information can help to improve patient care by providing doctors and other healthcare professionals with a more complete picture of a patient's health. In addition, healthcare integration can help to reduce costs by eliminating the need for duplicate tests and procedures. As healthcare mobile app development continues to evolve, healthcare integration will become increasingly important in providing patients with the best possible care. One such healthcare integration system is Redoxengine, let's look at its features in brief. The healthcare industry is under constant pressure to improve patient care while reducing costs. A major challenge in meeting these goals is the lack of interoperability between healthcare systems. The redox integration engine is a healthcare integration system that helps to overcome this challenge. It enables the exchange of data between disparate healthcare systems, allowing for coordinated care and improved patient outcomes. In addition, the redox integration engine can help to reduce healthcare costs by streamlining the flow of information and improving efficiency. As the healthcare industry continues to evolve, the redox integration engine will become an essential tool in providing high-quality, cost-effective patient care. For more details check the complete guide on healthcare interoperability and redox integration https://blogs.emorphis.com/guide-on-healthcare-interoperability-and-redox-integration/
Why Pharmacy Management System Essential for Pharmacy Business?
Since the availability of pharmacies in the market is huge, standing out and becoming a familiar player are not easy things. Also, the demand for a perfect management system is an essential thing to boost the working performance of pharmacy owners.  Focusing on these aspects, the development of the pharmacy management system Health360 – eMS is the serious one in the on-demand industrial sectors. Prior to knowing the development stages, it is important to know why the pharmacy management system is needed. The top reasons for this are listed as follows.  Operational Stability If the processes followed in the pharmacy delivery industry are completely synchronized and easily manageable, then the number of people actively participating in the pharmacy delivery business is more.  Moreover, the information stored in the system can be easily retrieved whenever and wherever applicable. Hence, the use of a perfect pharmacy management system assures operational stability for any task.  Digital Path for Effective Communication Pharmacy management software acts as the perfect digital medium for communication among the employees involved in the pharmacy business. To get the pharmacies in an ideal time, the communication between the pharmacy shop owners and the patients must be solid and effective. A clear understanding of prescriptions prior to medicine delivery is achievable with the use of the software. Efficient & Automated Platforms Compared to the manual process, the automated platforms are efficient with the imperative features reducing the operational time and increasing the efficiency of operation. With this tech assistance, pharmacy shop owners can easily handle the various pharmacy orders from any region.  Better Inventory The use of pharmacy management software improves inventory management in a new way. By consistently tracking the operations and there is any identification of absence of them, Health360 – eMS sends automatic reminders enabled within the software and allows the pharmacy shop owners to place the order quickly.  Right from the inventory stages to the delivery, the applicability of the pharmacy management software is high and everyone looks for such a platform in real time. To know more: http://bitly.ws/xcJA
THESE 7 SYMPTOMS OF FATTY LIVER DISEASE MIGHT SURPRISE YOU!
A new study has found that there are seven symptoms of fatty liver disease that people should be aware of.  The symptoms include fatigue, weight loss, abdominal pain, and more. The study found that these symptoms are often mistaken for other conditions, such as viral hepatitis or metabolic syndrome.  Fatty liver disease occurs when there is too much fat stored in the liver. This can lead to inflammation and scarring of the liver. If left untreated, fatty liver disease can lead to cirrhosis, liver failure, and death.  There are many symptoms of fatty liver disease, but these 7 may surprise you. TABLE OF CONTENTS What is fatty liver disease? What are the causes of fatty liver disease? How is fatty liver disease diagnosed? What are the 7 symptoms of fatty liver disease that might surprise you? What are the treatments for fatty liver disease? Conclusion: Living with fatty liver disease WHAT IS FATTY LIVER DISEASE? Fatty liver disease (FLD) is a condition in which too much fat accumulates in the liver. FLD can lead to inflammation and scarring of the liver, and can ultimately lead to liver failure.   Fatty liver can be caused by many things, including obesity, drinking too much alcohol, and certain medications. There are two main types of FLD: nonalcoholic fatty liver disease (NAFLD) and alcoholic fatty liver disease (AFLD).  NAFLD is the more common type of FLD and is often seen in obese individuals or those with diabetes.  In comparison, AFLD is more common in people with alcoholism and often occurs without other conditions.  Treatment for fatty liver disease includes lifestyle changes, such as losing weight and cutting back on alcohol, and sometimes medication. WHAT ARE THE CAUSES OF FATTY LIVER DISEASE? Fatty liver disease is the result of an accumulation of fat in the liver. The causes of this condition are not fully understood, but it is thought to be due to a combination of factors.  There are a variety of causes for this accumulation of fat, including obesity, diabetes, and alcohol abuse.  The most common cause of the fatty liver disease is obesity. Obesity leads to insulin resistance, which in turn causes the liver to produce more fat.  Diabetes and alcohol abuse can also cause the liver to produce more fat. In some cases, the cause of the fatty liver disease is unknown.  Fatty liver disease can lead to serious health problems, such as cirrhosis and liver failure.  Treatment for this condition typically involves lifestyle changes, such as weight loss and avoiding alcohol. HOW IS THE FATTY LIVER DISEASE DIAGNOSED? Fatty liver disease is the accumulation of fat in the liver. It is a common problem and often has no symptoms.  When symptoms do occur, they may include fatigue, pain in the upper right side of the abdomen, and yellowing of the skin and whites of the eyes (jaundice). Fatty liver disease (FLD) is a growing concern in the medical community. It is estimated that FLD affects between 30-50% of adults in the United States.  Although FLD is often asymptomatic, it can lead to more serious liver conditions such as cirrhosis and liver failure. Come on, let's dive into it.