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How COVID-19 Impacted on Niemann-Pick Disease in Healthcare Industry ?

COVID-19 Impact on Niemann-Pick Disease in Healthcare Industry

OVERVIEW

A novel coronavirus, SARS-CoV-2, appeared in December 2019 in Wuhan, China, spreading much faster than its predecessors and has already infected millions of patients worldwide as of April 19, 2020. As the scope of the current COVID-19 outbreak has reached the proportion of pandemics, significant international efforts in public health are underway to control the epidemic. The covid-19 pandemic majorly impacted the rare diseases patients because, during the pandemic, the need to provide high-level care for a large number of patients with COVID-19 has affected resourcing and limited the routine maintenance of all other conditions. The impact of health emergencies particularly faced by the rare disease communities, organizations, clinics, and other healthcare providers. The health economic challenges faced by patients and their families, institutions, research organizations, and healthcare providers during the pandemic outbreak have demonstrated the importance of ensuring continuity of care in the management of rare diseases, including adequate diagnostics and monitoring protocols, and highlighted the need for a structured emergency strategy.
Niemann-Pick disease is a rare, inherited disease that affects majorly body's ability to metabolize fats such as cholesterol and lipids within the cells. Over time, these cells got malfunctioned and died. The disease can affects the brain, spleen, nerves and, if get severe, may affect lungs, bone marrow, and other organs. The disease can occur at any age but majorly affects children. There is no known cure for the disease, and sometimes it may be fatal for children, the only treatment is focused on helping people live with their symptoms.

IMPACT ON PRICE

Various market players are facing a large number of challenges due to the coming of the novel coronavirus and different strains; one such issue is the uncertainty surrounding the impact of covid-19 on off label drugs demands. Due to the increased coronavirus cases and continuous lockdown, the costs of the drugs and their APIs increase automatically. On the one side, it will increase the revenue of the companies, but a patient may resist buying the products, which ultimately increases the stress level on the patients.
Moreover, Due to the pandemic, there is the delay associated with various types of limitations faced by the manufacturers to fulfill the end product order, which has resulted in the less availability of medical devices in the market and due to which the cost of available devices has increased with the several factors. Also, due to the Coronavirus disease (COVID-19) pandemic outbreak, manufacturers are forced to find new contract manufacturers and suppliers for more manufacturing activities to different or unique facilities location that are less impacted by the outbreak.
The impact of Covid-19 has created huge price impact on the government as well as on patient families that they have to buy the drugs on higher rate as compared to the average rate.

IMPACT ON DEMAND

The Coronavirus zone is the result of various markets around the world. This is the cause of the widespread closures and isolation that are affecting world economic activity. As the cases increases in the month of April 2020, the sudden surge in demand has seen, and drugs and medical devices went out of stock.
Moreover, the decrease in the revenue of the key market players depicted in their quarterly results, such as Medtronic, among others, gave the evidence of decline in the demand for medical devices due to the emergence of the COVID-19 pandemic.
For instance,
· Medtronic reported a decline of 1% in its brain therapies net sales of the financial results of 2020 as compared to 2019. The reduction was primarily motivated by the detrimental effects of the COVID-19 pandemic and the subsequent deferral to companies of medical procedures.
· Impact on rare disease organization also faced significant fundraising income loss, this consequential income loss may leads to loss of various people jobs associated with the organizations. The cutting or income loss leads to the reducing staff, canceling offices leases, and delay or cutting office programs.
The impact of covid-19 majorly impacted the organizations if the revenues loss projections do not change, this will leads to temporarily or permanently shut down of small and middle foundations and organizations.

IMPACT ON SUPPLY

As the epidemic intensifies, supply chains can be at significant risk due to over-located locations that can potentially be disrupted. The supply chain of drugs, devices, and services has been disrupted. The spread of COVID-19 makes it difficult for governments to use these drugs; the availability of these systems faces constant challenges due to their components of use and limited initial needs. Moreover, as there is no cure for the disease, only physical activities/therapies may suppress the symptoms also affected by pandemics.
According to the NORD (National Organization for Rare Disorders), in the U.S. stated that 74% of the population have had canceled medical appointments due to Covid-19 pandemic, 69% of population concerned about their medication and medical supplies.
For instance,
• In June, ResMed stated that, due to the Covid-19 pandemic company sleep apnea business segment adversely affected including sleep clinics, physician practices, HME suppliers. As new patients are prescribed sleep apnea devices such as PAP, CPAP devices for the treatment through hospitals that are directing their resources to critical care, including COVID-19 treatment. The covid 19 impacts may continue to decrease demand for the sleep apnea devices sale

STRATEGIC DECISIONS OF GOVERNMENT AND MANUFACTURERS

As such, market participants are involved in the production of drugs, expanding their business through a variety of programs, including collaboration, contracts, and pipeline development, collaboration, and market expansion. It is expected that the strategic decisions of these companies will provide significant opportunities for market participants operating in the Niemann-Pick Disease market.
For instance,
· In July 2020, Abbott announced that it had received FDA approval for the use of the Patient Controller App on compatible personal Apple smartphone devices. The approval will allow the patient living with neurological conditions to manage their therapy directly from personal smartphone.
· In May 2020, Philips, a global leader in health technology, joined forces with the American Telemedicine Association (ATA) to help further the adoption of telehealth across the industry, demonstrating its commitment to connecting care across acute, post-acute, and home care settings. The continued collaboration spotlights telehealth's growing adoption and momentum amidst COVID-19 and the need to convey the exponential shift to telehealth capabilities.
· In U.S., NIH supports the research survey of “CURE EPILEPSY ORGANIZATION” to examine the impact of Covid-19 on Rare Disease Community. The survey includes more than 200 rare diseases including the brain, immune system disorders, heart, lungs, brain development diseases, and more.

CONCLUSION

As this pandemic situation has resulted in many restrictions in different places around the world, still the market players of dealing in rare diseases therapy and services were able to manage their service stock. Different companies dealing in metabolic diseases therapy services were finding out their own way to deal with this pandemic situation. The government and companies around the globe are working together and have issued advice for those undergoing therapies centers during these unprecedented times during COVID 19 lockdown around the world.
The supply chain was destroyed, but several steps were taken by the government and companies, which will help them, get their needed output for therapy service. By increasing the material price, the companies can maintain their overall revenue.
Thus, different foundations, organizations,, and services center markets are finding ways to deal with this pandemic situation.
Figure 1: Relationship between Coronavirus and Lysosome storage diseases : Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway
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In that case, it is estimated that the demand for medical devices like endoscopes and colonoscopes which are used to treat juvenile polyposis, will downgrade by top importer countries. Suppose the lockdown continues to stretch for a longer period than anticipated. In that case, a huge drop is expected in non-surgical and surgical procedures worldwide, including the treatment of juvenile polyposis. Consequently, demand for the medical devices used in the procedure is anticipated to be minimized, which may decrease the price of the overall juvenile polyposis treatment procedure. Thus it is predicted that COVID-19 negatively affects the price of the juvenile polyposis treatment market. IMPACT ON DEMAND Coronavirus disease is an infectious disease that is caused by a SARS-CoV-2 virus. Currently, a huge population pool is affected by this COVID-19 virus. Coronavirus disease causes acute respiratory illness, ranging from mild to severe pneumonia with respiratory failure, and in rare cases, it is also associated with major cardiac complications. In order to reduce the spread of COVID-19, nearly all the countries have taken initiative action by lockdown and social distancing restriction. Due to affirmative restrictions, sudden shrink occurred in various surgical and non-surgical procedures requiring the patients' physical presence. Reduction in surgical and non-surgical procedures across the world has adversely affected the demand for the treatment of juvenile polyposis. Due to lockdown and social distancing restrictions, most patients prefer virtual vising through video calling or telehealth video visiting. Telehealth video visits are demanding alternative treatment such as medication for the treatment of certain diseases. Consequently, the growth of the juvenile polyposis treatment market is anticipated to downgrade as this procedure needs the patient to be physically present. For instance, · According to CDC, in 2019, 43 percent of the health centers were capable of providing telehealth services, while in 2020, during the COVID-19 pandemic, it was reported that 95 percent of the health centers were providing telehealth services · According to May 2020 article published by PMC, COVID-19 had a huge impact on surgical practice. There was a huge decline in the number of surgical procedures taking place, and also the surgeons are recommending safe, non-surgical alternative options to treat their patients during the pandemic IMPACT ON SUPPLY CHAIN COVID-19 has led to a disruption in the supply chain of medical devices, which are essential for treating and diagnosing juvenile polyposis syndrome. In different countries, diagnoses of other diseases have slowed down due to increased pressure to diagnose COVID-19. This led to a significant delay in diagnosing juvenile polyposis syndrome, which ultimately reduced the number of treatment procedures. The COVID-19 pandemic has truly transformed some organizations' business environment; the organizations' supply chain has been hampered by several issues, including export and travel restrictions by some countries and lockdowns that have forced suppliers to shut down in the majority of the cases temporarily. 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How COVID-19 Impacted on Periodontitis in Healthcare Industry ?
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Significant Impact of COVID-19 on Advanced Anesthesia Monitoring Devices in Healthcare Industry
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Following the pandemic’s declaration, numerous countries have declared the full lockdown, including the U.S., Germany, India, and China to limit its spread. The overall fall in the demand for advanced anesthesia monitoring devices was observed during the COVID-19 pandemic due to a decrease in the number of surgeries. The effect on the healthcare industry has also been dramatically impacted and a huge pressure is being created on healthcare services that are already stressed across the globe. Emerging technological advancements has further escalated the demand for advanced anesthesia monitoring devices in the market. IMPACT ON PRICE The coronavirus disease (COVID-19) pandemic has had an enormous impact on the global advanced anesthesia monitoring devices market. The demand for advanced anesthesia monitoring devices services across the globe is anticipated to decrease due to the patient pool which cancelled their scheduled and elective surgeries. If the COVID-19 continues to spread for prolong period, then it is estimated that the demand for advanced anesthesia monitoring devices services will downgrade by developed as well as developing countries. Moreover, top advanced anesthesia monitoring devices importer countries such as United States, Europe is primarily concentrating to deal with Coronavirus (COVID-19); owing to this reason demand for these advanced anesthesia monitoring devices has decreased from the United States followed by Italy. If the lockdown continues to stretch for long period then a huge reduction may take place in several surgeries, which may lead to a decrease in the price of advanced anesthesia monitoring devices. Resulting it is predicted that COVID-19 has an adverse impact on the price of advanced anesthesia monitoring devices. IMPACT ON DEMAND Coronavirus disease (COVID-19) is an infectious disease caused by a SARS-CoV-2 virus while a large pool of the population is affected by this COVID-19 virus. Coronavirus disease (COVID-19) causes acute respiratory illness ranges from mild to severe pneumonia with respiratory failure. To minimize the spread of COVID-19, nearly all the countries have taken initiative action by the virtue of locked down and social distancing restriction. Owing to such affirmative factors, demand for advanced anesthesia monitoring devices has been minimized. But due to lockdown and social distancing restrictions, the majority of the patient pool are preferring virtual vising through video calling or telehealth video visiting. For instance, · According to the report published by the British Journal of Surgery, in May 2020, an estimated 585,000 elective surgeries were postponed in the 12-week lockdown in India alone, and 28.4 million elective surgeries worldwide are expected to be cancelled or postponed. Thus, the cessation of surgical procedures is the major factor that is likely to hamper the usage of advanced anesthesia monitoring devices. STRATEGIC DECISIONS OF GOVERNMENT AND MANUFACTURERS A large pool of the population affected by this COVID-19 virus and spread is expanding across the world for the last few months. To deal with the COVID-19 outbreak challenges, many advanced anesthesia monitoring devices market players are creating new strategies. To tackle the pandemic situation and increase the company revenue and growth, the company now opting for digital media such as telecommunication, mobile applications, webinars, and other digital media to support the patient requirement. Moreover, to accomplish the market demand, small market players utilizing the partnership agreement strategy. It is predicted that these strategies are anticipated to escalate up the company revenue and its growth in the forecasted period. IMPACT ON SUPPLY CHAIN The COVID-19 pandemic has transformed many organizations’ business environments; supply availability has been hampered by several issues, including export and travel restrictions by some producing countries, and lockdowns that have forced suppliers to (temporarily) shut down. To minimize supply chain crises, healthcare organizations have been firmly monitoring the supply chain with the assumption that the COVID-19 outbreak may adversely impact the supply chain of medical devices, including shortages of advanced anesthesia monitoring devices or potential disruptions in its supply chains. To manage such a crucial situation many organizations are looking forward to improving and diversify supply chain models in all aspects. A diversified supply chain model is anticipated to minimize the export of medical devices as well as increase end-to-end visibility. The resulting COVID-19 pandemic has shown the various ways for supply chain management which may be effective within a remote working environment. CONCLUSION It can be concluded that the COVID 19 pandemic situation has an enormous impact on the global advanced anesthesia monitoring devices market due to a decrease in the number of surgeries. However, companies as well as government bodies exclusively concentrating on how they can make the most effective and best contribution to control the spread of the virus and save lives. They also ramping up the production of essential medication to a new level and ensure that speed does not affect or destroy the quality of products.
Growing Support and Collaboration for Developing OTC Tests
 The growth of the OTC tests market is mainly driven by the rising prevalence of target diseases and disorders, such as diabetes and infectious diseases, both prominent ailments across the globe that require rapid and effective testing.  Growth in this market can be attributed to factors such as the increasing number of HIV-infected individuals across the globe, coupled with increasing availability and awareness about HIV OTC testing in emerging markets such as India, Brazil, and China.   The lateral flow assays segment is projected to grow at the highest rate in the market, by technology. In the past few years, the lateral flow assay POC testing market has grown significantly due to the increasing adoption of LFA testing products in-home care.   Download PDF Brochure @ https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=78819178 The Asia Pacific is estimated to grow at the highest CAGR during the forecast period. The high growth in this regional segment is majorly attributed to the increasing patient population base and the growing prevalence of infectious diseases.  Key market players The key players operating in the global Over The Counter/OTC test industry are OraSure Technologies (US), Roche Diagnostics (Switzerland), and i-Health Lab (US). A majority of the leading players in the market focus on both organic and inorganic growth strategies such as collaborations, partnerships, acquisitions, and agreements to maintain and enhance their market shares in the OTC tests market.  Research Developments: 1. In 2019, SD Biosensor launched STANDARD GlucoNavii GDH for blood glucose monitoring. 2. In 2019, LabStyle Innovations entered into an agreement with Better Living Now (BLN) for the distribution of its Blood Glucose Monitoring System and the DarioEngage digital health platform. 3. In 2018, DarioHealth partners with Byram Healthcare to further expand insurance health coverage for consumers in the US. 4. In 2016, Sinocare acquired PTS Diagnostics, to strengthen its product portfolio and accelerate future growth in the diagnostic testing market. 
How COVID-19 Impacted on Bevacizumab in Healthcare Industry ?
COVID-19 Impact on Bevacizumab in Healthcare Industry In the city of Wuhan, China the Coronavirus disease (COVID-19) outbreak is originated. Coronavirus disease (COVID-19) has spread across the globe, with large number of cases having been reported worldwide. The Coronavirus disease (COVID-19) pandemic is not only creating health crisis but also it is unfavorably affecting on healthcare, economies and pharmaceutical sector as well as at their core. As COVID-19 is the infectious disease, its spread is endless. It have causes a nationwide outbreak as well as public health crisis. Cancer treatment and therapies drugs manufacturing companies have also faced some difficulties in manufacturing and distribution of the drugs and medication due to locked down, supply chain and social distancing restrictions. In some recent studies, it was stated that Bevacizumab, an anti-VEGF drug, approved by the FDA and widely used in clinical oncotherapy, is a promising drug for ALI/ARDS in COVID-19 through suppression of pulmonary edema which have increased its demand in the market and also increasing cancer patients have also driven the market demand and supply. PRICE IMPACT The Coronavirus disease (COVID-19) pandemic has an enormous impact on the global economy market. The demand for cancer treatment products has increased along with its prices in the treatment of COVID. In addition, the sum of research and development and marketing, selling, and administrative expenses have been increased in 2020, which is driven primarily by the development expenses for COVID-19 therapies. For instance, Bevacizumab plus standard care markedly improves the oxygen ratios in COVID 19 patients and shows improvement in oxygen-support status, patients were discharged, and none of the patients have shown worsen oxygen-support status nor die. Also, the demand for cancer treatment products will be increased, and the products are upgraded by top importer countries like U.S., which have increased the sales and prices of the bevacizumab. For instance, The drug Avast in (bevacizumab) has been increased to $842 for a supply of 4 milliliters dose in 2020. Due to the increase in demand, the use of bevacizumab in the COVID treatment and increase in production and manufacturing expenses have contributed to product prices. IMPACT ON SUPPLY CHAIN The COVID-19 pandemic has transformed many organizations’ business environment; several problems, including export and travel ban by some producing countries and lockdowns that have caused producers to (temporarily) shut down, have disrupted supply access. Difficulties or delays in manufacturing, sales, or marketing; supply disruptions, shortages, or stock-outs at our facilities; and legal or regulatory actions all are caused due to the COVID 19 pandemic. But it does not affect the sales and supply of the drug bevacizumab that much because of the rise in new diagnoses or cancer and the efficiency of the drug in treating the COVID patients. These are some of the reasons which have maintained the supply of the drug throughout the year With the rise in demand and supply of the drugs, many manufacturing companies have launched their new products, which have increased their sales. For instance- · The sales of the drug MVASI (bevacizumab) from the manufacturing company Amgen Inc. have increased more than 20% in the U.S., which is USD 121 million in 2019 to USD 650 million in 2020 and for the rest of the world, drug sales increased from USD 6 million in 2019 to USD 142 million in 2020. This increase in the supply of the drug is with the increasing treatment for cancer. · Similarly, the sales of the global segment generics, which include biologics drugs such as bevacizumab of the company Dr. Reddy’s Laboratories Ltd, have also been increased from USD 1,858.27 million in 2019 to USD 2,079.96 million in 2020. This increase in sales is due to the increase in healthcare and Research & Development due to COVID 19. IMPACT ON DEMAND Coronavirus disease (COVID-19) is an infectious disease caused by a SARS-CoV-2 virus, while a large population is affected by this COVID-19 virus. Coronavirus disease 2019 (Covid-19) is an ongoing worldwide pandemic; nearly all the countries have taken initiative action under locked down and social distancing restriction. Reduction in cancer treatment across the globe has affected the demand for cancer treatment and their drugs like bevacizumab, especially in the first quarter, but after the second quarter of 2020, the demand for the drug has increased because of its Efficacy and tolerability of in patients with severe COVID-19. For Instance- Recent evidence revealed higher blood Vascular Endothelial Growth Factor (VEGF) levels in COVID-19 patients compared with healthy controls. VEGF is considered the most potent vascular permeability inducer. Numerous studies have revealed that VEGF was a key factor and a potential therapeutic target in ALI and ARDS. Bevacizumab, an anti-VEGF drug, approved by the FDA on February 26, 2004, and widely used in clinical oncotherapy, is a promising drug for ALI/ARDS in COVID-19 through suppression of pulmonary edema. Also, the increase in cancer patients and the rise in the demand for the treatment of various types of drugs have propelled the market demand and sales of major market players. For instance, · There is an increase in the sales of biosimilar drugs which includes bevacizumab, for major market players. For instance, the manufacturing company Pfizer Inc., the sales of biosimilar segment is increased from USD 1,527 million to USD 911 million with the increase in demand for the drugs in COVID patients and the cancer treatment. STRATEGIC DECISIONS FOR MANUFACTURERS A large population is affected by this COVID-19 virus, and its spread is expanding worldwide for the last few months. To deal with the COVID-19 outbreak challenges, many bevacizumab and biosimilar market players are creating new strategies. The company is now opting for digital media such as telecommunication, mobile applications, webinars, and other digital media to support patient requirements to tackle the pandemic situation and increase the company sales with the increasing demand and growth. Moreover, to accomplish the market demand, small market players are utilizing the partnership agreement strategy. It is predicted that these strategies are anticipated to escalate up the company revenue and its growth in the forecasted period. They have launched new products and formed strategic alliances with each other to carry on the supply during the pandemic. For instance- · In 2020, Amgen Inc. had advanced their innovative pipeline, successfully integrated MVASI, acquired in November 2019, a biosimilar to Avast in (bevacizumab), and has advanced their international expansion continued to provide an uninterrupted supply of their medicines globally through the COVID-19 pandemic · In May 2020, the Food and Drug Administration approved atezolizumab in combination with bevacizumab (TECENTRIQ and AVASTIN, Genentech Inc.) for patients with unrespectable or metastatic hepatocellular carcinoma who have not received prior systemic therapy CONCLUSION It can be concluded that the COVID-19 pandemic has a positive impact on the global bevacizumab market with the increase in the price, supply, and demand of the bevacizumab. However, in the crisis call, pharmaceutical market players, government bodies, and healthcare organizations work closely with healthcare professionals, customers, and patients for the betterment of public health and to fulfill the demand. However, companies and government bodies exclusively concentrate on how they can make the most effective and best contribution to control the spread of the virus and save lives. They are also ramping up the production of essential medication to a new level and ensure that speed doesn’t affect or destroy the quality of products.
Refurbished Medical Equipment Market is Set to $21.2 billion by 2025
The growth of the global refurbished medical equipment market can be attributed to factors such as hospital budget cuts, a large inventory of used or old medical devices, rising demand for capital-intensive diagnostic imaging equipment, e-commerce platform enhancing the ease of purchase of refurbished medical equipment, growing preference for eco-friendly products, an increasing number of diagnostic centers & hospitals, and the growing opportunities in emerging economies.  However, factors such as stringent regulations on the import and use of refurbished medical devices in certain countries, lack in the standardization of policies for the use & sale of refurbished devices, increase in the influx of low-cost new medical devices, and the negative perception about the quality of refurbished medical devices are expected to restrain the market growth. Furthermore, the growth of the market is expected to be slowed temporarily due to the COVID-19 pandemic during the forecast period.  The refurbished medical equipment market is segmented into medical imaging equipment, operating room & surgical equipment, patient monitors, cardiology equipment, urology equipment, neurology equipment, intensive care equipment, endoscopy equipment, IV therapy systems, and other medical equipment.  Download PDF Brochure @ https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=770 The rising demand for diagnostic imaging procedures, the high price of new medical imaging equipment, a growing number of target diseases, widening application of diagnostic imaging procedures, regulatory approvals in using refurbished medical equipment, low purchasing power in emerging economies, and established & government validated refurbishment processes adopted by major OEMs are factors expected to drive the growth of this market segment in the coming years.  The hospitals' segment accounted for the largest share of the market in 2019. The rising adoption of refurbished medical equipment, increasing focus of hospitals on providing affordable treatment and care, and growing emphasis on high returns on investment are some of the key factors driving the growth of this market.  The Asia Pacific market is estimated to grow at the highest CAGR during the forecast period. This can be attributed to the large patient pool in the region, increasing privatization in the healthcare sector, huge patient population base, and high demand for refurbished medical equipment by low-budget hospitals and clinics.  Research Developments 1. In 2020, Siemens Healthineers (Germany) and Hamilton Health Sciences (Canada) have signed a 15 years contract that can be extended by another 10 years to provide comprehensive services for the latest imaging equipment at Hamilton Health Sciences hospitals in Canada. The deal size was approximately USD 192 million. 2. In 2019, US Med-Equip (US) acquired Medical Support Products (US) to increase the capability, national expansion, and provide greater product and service solutions across the US. 3. In 2019, Avante Health Solutions opened a new Charlotte facility in North Carolina, US. This will house three business divisions of the company viz., Avante Diagnostic Imaging, Avante Oncology, and Avante Ultrasound. 4. In 2018, Koninklijke Philips (Netherlands) acquired AGITO Medical (Denmark), strengthening its refurbished medical equipment portfolio of products, parts, and services. 5. In 2017, US Med-Equip  (US), and the Owner-Research group (US) signed a partnership to augment the economy and medical equipment products and services across hospitals in the US.
Significant COVID-19 Impact on Hearing Aids in Healthcare Industry
COVID-19 Impact on Hearing Aids in Healthcare Industry The COVID-19 has affected the global hearing aids market. The persistence of COVID-19 for a longer period increased the demand for hearing aids services across the global region. During, COVID-19 pandemic, the countries were expecting a large number of patients with the impaired hearing which results as one of the symptoms of COVID-19 disease. Moreover, the increased geriatric population across the globe with the hearing inabilities due to their age is a major factor driving the global hearing aids market. The rising number of patients suffering from hearing inabilities and hearing loss coupled with the increasing demand for the advanced level and effective technology hearing aids to provide to the patients will boost the growth of the market. The demand for hearing aids for the patients which is a rare symptom of COVID-19 has overall decreased during the COVID-19 crisis. IMPACT ON THE DEMAND OF THE GLOBAL HEARING AIDS MARKET The global hearing aid market was negatively impacted by the pandemic. The hearing care industry is dependent on close customer contact. Due to stringent precautionary measures announced by the government, close human contact was discouraged or required special measures in the clinics and the audiology shops. As a result, less severe hearing loss-related procedures were delayed during the pandemic which impacted the sales of hearing aids. Despite these challenges, manufacturers implemented measures to meet the high demand for timely professional hearing care. Due to product innovation and re-inventing supply chain, major players in the hearing aids market were able to sustain demand and cater to the hearing healthcare market even during the pandemic. INITIATIVES BY THE MANUFACTURERS: There are some important initiatives taken up by the key market players to overcome the COVID-19 impacts on the current market scenario. Some of them include the launch of technologically advanced devices in the global market to meet the growing demand for hearing aids. For instance, In 2020 GN hearing launched Resound ONE that solves one of the most enduring challenges for people with hearing loss. This solution places an additional microphone inside the ear canal with a microphone and receiver in-ear design that uses the unique shape. Manufacturers are trying to meet the growing demand and improving their product portfolio to acquire a larger market share by launching new products that are preferred by the consumers. For instance, · In January 2021, Oticon Inc launched Oticon More, a new hearing aid that builds on the company’s proven brain hearing approach to provide the brain optimum input for better speech understanding with less approach. · In March 2020, Widex launched the moment hearing device. The widex moment has the classic widex signal pathway which is paired with a second ultra-fast signal pathway that adds extra gearing to the platform. Therefore, these innovative launches made by the manufacturers across the market during the COVID-19 and post-pandemic period are expected to increase their sales and revenue by meeting the growing demands of the patients in the market. IMPACT ON THE SUPPLY CHAIN Although there was a demand for hearing aids among consumers around the globe region due to the increasing hearing loss, the COVID-19 has disrupted the supply chain as well as consumer’s willingness to adopt elective healthcare. The COVID-19 has negatively impacted the market supply chain due to the lack of labor and transportation of the raw materials. Due to the sudden outbreak of the COVID-19 pandemic, the governments in the world have declared a strict lockdown to control the spread of disease. This has majorly affected the supply chain as there is not sufficient labor in the manufacturing facilities, resulting in the lack of hearing aid products in the market. Due to the sudden burden of lockdown, the raw materials have not been shifted from the source places by causing a severe scarcity of raw materials for the manufacturers. This has affected the export of hearing aid products to other needful countries. However, in the post lockdown period, the manufacturers have recovered from the scarcity of the raw materials and resumed production. CONCLUSION The sudden onset of the COVID-19 pandemic has resulted in negative impacts on the supply chain of the global hearing aids market. The COVID-19 has caused lots of health issues including the hearing inability in rare cases which increased demand for hearing aids. This is positively impacting the growth of the global hearing aids market as there is an increasing geriatric population around the globe with common hearing problems. However, the increase in the hearing inability diseases among the population due to various reasons such as noise pollutions, genetic disorders among others has increased the demand for hearing aids even in the COVID-19 pandemic.
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How COVID-19 Impacted on Neurophotonics in Healthcare Industry ?
COVID-19 Impact on Neurophotonics in Healthcare Industry Coronavirus disease (COVID-19), also known as SARS-CoV-2 or 2019-nCoV, is a human infectious disease caused by the Coronavirus that causes extreme acute respiratory syndrome. On March 11th, 2020, the World Health Organization declared the coronavirus COVID-19 outbreak to be a pandemic due to the rapid rise in human infection rates (WHO). Neurophotonics is an open-access journal that publishes research on improvements in optical technology for brain research and their impact on basic and clinical neuroscience applications. In the current situation, producers face difficulties with existing immature goods suppliers or contractors who are at risk or closed or unable to meet supply requirements due to challenges such as extended closing hours or staffing. Manufacturers are required to qualify a new contract manufacturer (or new manufacturing facility) to supply raw materials. Any changes in the third party for the supply of raw materials, components, and commercialization of ophthalmic surgery devices could increase cost of production and can reduce profit margins, forcing manufacturers to increase the prices of the product to remain operative in the market. IMPACT IN DEMAND The demand for optical coherence tomography for ophthalmology market is decreased with an increase in the number of COVID-19 cases and cancellation or deferral of elective surgeries. The ophthalmic lasers market saw a severe drop in the second and third quarters of 2020. The international supply of lasers was restricted due to a lockdown and severe procedure rules. The COVID-19 scenario has resulted in the postponement of specific elective medical procedures, impacted the demand for reprocessing systems and services. Within the healthcare general surgery domain, there has been increased concern regarding the level of acquired infections. As the COVID-19 pandemic is accelerating at a fast pace, it has raised pressure for the healthcare systems to deal with potentially infectious patients. The pandemic had placed severe pressure on the U.S. economy. The manufactures of ophthalmology and generic medications were impacted by the global epidemic due to the rise in demand for essential products and suppliers to prevent COVID-19. The demand will have a positive impact on the market growth. IMPACT ON SUPPLY The COVID-19 outbreak has disrupted the supply chains for the entire manufacturing sector. According to the Institute for Supply Chain Management, 75 percent of the companies reported disruptions in the supply chain due to restrictions in transportation by the coronavirus. Also, 50 percent of the companies reported unexpected delays in receiving the orders, a problem compounded by a supply chain information blackout from China. The COVID-19 pandemic has transformed many organizations’ business environments; supply availability has been hampered by several issues, including export and travel restrictions by some producing countries and lockdowns that have forced suppliers to (temporarily) shut down. However, disturbance in the neurophotonics products market puts global supply chains at risk. Healthcare organizations have been firmly monitoring the supply chain with the assumption that the COVID-19 outbreak may adversely impact the supply chain of the medical product, including shortages of neurophotonics products or potential disruptions in its supply chains to minimize supply chain crises. Several organizations are looking forward to improving and diversifying supply chain models in all aspects to manage such a crucial situation. A diversified supply chain model is anticipated to minimize the export of medical products and increase end-to-end visibility. The resulting COVID-19 pandemic has shown the various ways for supply chain management, which may be effective within a remote working environment. STRATEGIC DECISIONS FOR MANUFACTURERS Many neurophotonics products market players are creating new strategies to deal with the COVID-19 outbreak challenges. The companies are now opting for digital media such as telecommunication, mobile applications, webinars, and other digital media to support the patient requires tackling the pandemic situation and increasing the company revenue and growth. Moreover, to accomplish the market demand, small market players utilizing the partnership agreement strategy. It is predicted that these strategies are anticipated to escalate up the company revenue and its growth in the forecasted period. The key players engaged in providing products face challenges to keep the growth during coronavirus and maintain the demand and supply chain with the proper protection of their employees. During the epidemic, telemedicine has become a fundamental approach for ophthalmologists to stay in touch with patients from the comfort of their own homes. CONCLUSION The impact of the novel COVID-19 virus is expected to leave a long-lasting impact on each industrial sector. The outbreak of COVID-19 prompted citizens to deal with confusion regarding the virus and its management. The virus poses a risk to human life and has caused economic distress and severe emotional strain. It produced a wave effect that gave rise to a new collection of requirements and needs that were not needed earlier. The growing prevalence of contagious infections and COVID-19 has necessitated a stable healthcare network and adequate emergency medical services (EMS). Hence the reprocessed medical devices should be readily available for the emergency treatment of patients who suffer from other chronic diseases apart from COVID-19. However, the changes in the International Standard Organization (ISO) for neurophotonics, the strict regulatory framework, the consequences of the contractual agreement, and the disruption in supply chain management can hamper the market growth. There are no data on the safety, immunogenicity, or effectiveness regarding the treatment of patients with infections along with mild COVID-19 symptoms. The supply chain units are taking stringent measures and risk mitigation protocols to provide and distribute the diagnostic devices to the manufacturers to the customer. The presence of key market players for the development and launch of disposable PPE will increase net sales and show a surplus growth. Despite the indication of vaccination on the horizon, the pandemic is here to live for a considerable amount of time. However, the treatment will remain the same, irrespective of the SARS- COV 2 coinfection. The guidelines for the reuse of medical devices during the COVID -19 pandemic increase the need for prevention from infections. Specific recommendation guidelines should be taken care of while using reprocessed medical devices and services. A comprehensive approach for the prevention, screening and treatment of chronic diseases requires outsourced medical device services. This can reduce the cost savings. With the ongoing pandemic, the demand for topical medications and vaccines from the health community is increasing.
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Why You Need A Niacinamide Serum? And How To Use It.
Niacinamide may not get as much attention as retinol and vitamin C, but it is a skincare powerhouse that deserves equal recognition. It is the definition of a multitasker, offering a host of distinct benefits that make it a good choice for a wide range of skin types and complexion issues. However, incorporating it into your current skincare routine might sound difficult. Is it OK to use niacinamide along with vitamin C and/or retinol? Is hyaluronic acid a viable alternative? We weigh in on everything you need to know about using niacinamide. What is niacinamide, exactly? Simply put, it's a B vitamin, one of two forms of vitamin B3, and it participates in a number of critical cellular operations in the skin. What benefits does it have for the skin? Buckle your seatbelts, because this is going to be a long list. Niacinamide is a fantastic treatment for acne-prone skin. Niacinamide reduces sebum production, which can help prevent acne and shine. The vitamin is also known for its anti-inflammatory qualities, which aid in the treatment of acne and other skin conditions such as eczema. Niacinamide helps to build the skin barrier, which is advantageous to people who have eczema or sensitive skin. It is also an efficient skin lightening agent, treating hyperpigmentation by blocking pigment transfer from pigment-producing cells known as melanocytes to skin cells on the surface where discoloration is visible. As if that wasn't enough, there's evidence that niacinamide can help to reduce wrinkling and photoaging by maintaining cell function and repairing DNA damage. To summarise, niacinamide has very few limitations. Is it OK to mix niacinamde and retinol? Yes! In fact, retinol and niacinamide are recommended together for faster effects. The soothing characteristics of niacinamide can also assist to alleviate the unpleasant side effects and irritation that usually accompany retinol's wrinkle-fighting effectiveness. Is it safe to combine with other ingredients? Yes, as a general rule, which is why it's found in many skincare products and is easy to incorporate into your present routine. Niacinamide is frequently coupled with salicylic acid, a beta-hydroxy acid typically found in acne products, due to its acne-fighting qualities. Combining niacinimadie's oil-removal properties with salicylic acid's ability to break down excess oil is an effective way to keep pores free and breakouts at bay. Niacinamide is an ideal choice for combining with alpha-hydroxy acids, which are chemical exfoliants that can cause skin irritation, due to its anti-inflammatory and skin barrier-strengthening effects. Because the AHAs exfoliate the dead skin cells that would otherwise make it impossible for the niacinamide to enter, combining them boosts the efficacy of the niacinamide. Finally, because niacinamide and hyaluronic acid can both help with dry skin, they are frequently mixed. What is the one thing that the jury is still out on? Vitamin C. Because vitamin C might inactivate niacinamide, the applications should be separated by 15 minutes. In truth, the two would have to be heated in order to interact negatively, and more and more cosmetics are combining the two in skin-brightening formulations. The bottom conclusion is that if you utilise a product that contains both vitamin C and niacinamide, it was most likely specifically designed to work together. If you're using two different products that include these chemicals, wait 15 minutes between applications or use one in the morning and the other in the evening. Should I use niacinamide? Sure, in a nutshell. One of the nicest aspects of niacinamide is not only the vast list of benefits it offers, but also how well it is tolerated, particularly by those with sensitive skin. This makes it an enticing choice for those whose skin is sensitive to more common acne or skin lightening agents like benzoyl peroxide or retinoids.
mHealth Solutions Market worth $213.6 billion by 2025 - Exclusive Report by MarketsandMarkets™
According to the new market research report "mHealth Solutions Market by Connected Devices (Glucose & Blood Pressure Monitor, Peak Flow Meter, Pulse Oximeter), Apps (Weight Loss, Women Health, Diabetes Management, Mental Health), Services (Remote Monitoring, Consultation) - Global Forecast to 2025",is projected to reach USD 213.6 billion by 2025 from USD 50.8 billion in 2020, at a CAGR of 33.3 % during the forecast period. The growing adoption of smartphones, increasing penetration of 3G/4G networks, rising focus on cost containment in healthcare delivery, and the increasing demand for home healthcare services are some of the key factors driving the growth of this market. Browse in-depth TOC on " mHealth Solutions Market 303 -Tables 43- Figures 291- Pages Download PDF Brochure: - https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=1232 The mHealth apps segment accounted for the largest share of the mHealth solutions market in 2019 Based on product and service, the mHealth apps segment accounted for the largest share of the mHealth solutions market in 2019. The large share of this segment can be attributed to the high and growing penetration of smartphones and healthcare apps and the rising incidence of chronic and lifestyle-related diseases across the globe (coupled with the effective utilization of apps in chronic disease management). Based on region, North America accounted for the largest share of the mHealth solutions market in 2019 Based on region , the mHealth solutions market is segmented into North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. North America accounted for the largest market share in 2019. This is due to the increasing penetration of smartphones, rising prevalence of chronic and lifestyle disorders, increasing healthcare costs, increasing demand for better healthcare services, government initiatives to promote digital health, robust penetration of 3G and 4G networks, and the rising awareness of self-health management. Request Sample Pages: - https://www.marketsandmarkets.com/requestsampleNew.asp?id=1232 The prominent players in this market are Medtronic plc (Ireland), Apple, Inc. (US), AirStrip Technologies (US), AliveCor, Inc. (US), Nike, Inc. (US), Koninklijke Philips N.V. (Netherlands), Johnson & Johnson (US), Omron Corporation (Japan), BioTelemetry, Inc. (US), athenahealth, Inc. (US), AgaMatrix, Inc. (US), Withings S.A. (France), and iHealth Labs, Inc. (US).
Pharmaceutical Packaging Equipment Market worth $10.4 billion by 2025 - Exclusive Report by MarketsandMarkets™
According to the new market research report "Pharmaceutical Packaging Equipment Market by Product (Aseptic Packaging, Blister, Strip, Bottle, Tube, Carton, Case Packer, Wrapping Machine, Palletizing, Labeling & Serialization), Type (Tablet, Powder, Cream, Syrup, Aerosol), Region - Global Forecast to 2025", published by MarketsandMarkets™, the global Pharmaceutical Packaging Equipment Market size is projected to reach USD 10.4 billion by 2025 from USD 7.3 billion in 2020, at a CAGR of 7.4% from 2020 to 2025. Browse in-depth TOC on "Pharmaceutical Packaging Equipment Market" 276 – Tables 48 – Figures 330 – Pages Download PDF Brochure:-https://www.marketsandmarkets.com/pdfdownloadNew.asp?id=19845828 The growth of the global pharmaceutical packaging equipment industry is driven by the rapidly growing generic and biopharmaceutical markets, growth in OTC drug sales, rising need for flexible and integrated packaging equipment, increased offshore manufacturing in the pharmaceuticals market, and the introduction of regulatory standards on packaging and stringent norms against counterfeiting. Primary packaging equipment accounted for the largest share in the market in the forecast period. On the basis of product, the pharmaceutical packaging equipment market is segmented into primary packaging equipment, secondary packaging equipment, and labeling and serialization equipment. In 2019, the primary packaging equipment segment accounted for the largest share of the market. The main function of primary packaging is to restrict climatic, chemical, or biological hazards that cause deterioration. The rising need for the aseptic filling and sealing of drug molecules into sterile containers and the increasing demand for parenteral vials and prefillable syringes are supporting the growth of this segment. Liquid packaging equipment expected to show the highest growth in the forecast period. Based on type, the pharmaceutical packaging equipment market is segmented into liquid, solid, semi-solid, and other packaging equipment. In 2019, the liquid packaging equipment segment accounted for the largest share of the market, followed by solid and semi-solid packaging equipment segments. The largest share can be attributed to the wide range of applications of liquid pharmaceutical dosage as they can be administered via either the oral or the parenteral route. Their palatability makes them a product of choice for geriatric and pediatric patients. Get 10% Customization on this Research Report :-https://www.marketsandmarkets.com/requestCustomizationNew.asp?id=19845828 Europe to hold the largest share in the global market during the forecast period of 2020–2025. Geographically, the pharmaceutical packaging equipment market is segmented into North America, Europe, the Asia Pacific, Latin America, and Middle East & Africa. Growth in the European market is driven majorly by the high pharmaceutical production, increasing demand for flexible packaging equipment by major pharmaceutical manufacturers, and the rising focus on product diversification by companies, driving the demand for innovative packaging equipment. Regulatory changes are also compelling pharmaceutical manufacturers to replace their older equipment with new equipment to adhere to the changing standards. The prominent players in this market are Syntegon Technology (Germany), IMA S.p.A. (Italy), Körber AG (Germany), Uhlmann Group (Germany), OPTIMA Packaging Group (Germany), Romaco Holding (Germany), Marchesini Group (Italy), ACG Worldwide (India), Coesia S.p.A. (Italy) and MULTIVAC Group (Germany).