Some hormonal medicines may lead to bone and joint pain. 1. Talk to your doctor as soon as you have bone or joint pain. - Don’t let the pain become intolerable. - You may be able to switch to a different hormonal therapy medicine that may ease your pain. 2. Pain medicines, such as naproxen and ibuprofen. 3. Some complementary and holistic medicine, including acupuncture, chiropractic therapy, massage, music therapy, and hypnosis. 4. Hot or cold packs, or a combination of the two, can soothe sore areas. Heat can help reduce muscle spasms and cold can help reduce inflammation. 5. Eat a healthy diet that includes enough calcium and vitamin D to keep your bones as strong as they can be. 6. Maintain a healthy weight to ease stress and strain on your joints. 7. Exercise regularly. Exercise keeps your bones strong and helps your joints stay flexible. A study presented in December 2013 found that exercise can ease the joint pain caused by aromatase inhibitors.