Like a lot of teenagers, Peter Parker is trying to figure out who he is and how he has become the person he is today. Peter is also trying to cope with his first high school crush, Gwen Stacy, and together, they struggle with love, commitment, and secrets. When Peter discovers a mysterious briefcase belonging to his late father, he tries to uncover more about his parents' disappearance. This leads his to Oscorp and the lab of Dr Curt Connors, his father's former partner. As Spider-Man is set on a collision course with Connors' dark side, The Lizard, Peter will make life-changing choices to use his new found powers and become a hero.