The History behind Viagra Sildenafil

Sildenafil was originally developed as a treatment for cardiovascular diseases however patients started to experience side effects such as erections which led to the idea of it being used for erectile dysfunction (ED). The treatment was manufactured by Pfizer and was introduced to the market following FDA approval in 1998. The tablet was sold under the brand name Viagra. In 2012 the patent for Viagra expired in countries outside the United States which made way for the sale of Viagra Sildenafil (generic Viagra).Viagra is now available as a generic medication called Sildenafil which can now be manufactured and sold by a variety of companies. Today, sildenafil is available in a variety of forms however it is most commonly sold in tablet form. The only major difference between generic Viagra and the original is the name. Viagra is a brand name medication invented and marketed by Pfizer, while sildenafil (or sildenafil citrate) is the active ingredient in Viagra. The ingredient single handily combats erectile dysfunction and is present in generic Viagra Sildenafil (generic Viagra) as well. Once the patent for Viagra expired, the well- known Viagra name was dropped assome of the generics that were developed thereafterwere named Sildenafil. Although Sildenafil tablets are generic, it still remains as effective as its predecessor. The medication boasts the same pharmacological profile as Viagra and is a less expensive substitute which produces the same results. It is also easily accessible as it can be bought from online pharmacies. When should Sildenafil Use be Avoided? Not all men with erectile dysfunction can take Sildenafil Teva. As with any medication, there are certain medical conditions and treatments that do not allow the use of this medication.

An overview of the best place to buy generic Viagra online

When sildenafil gained FDA approval, it became the first safe tablet that can be taken orally to treat erectile dysfunction, or ED. Before it was invented, medical treatment for ED was limited. The only therapies that were available at the time were physically intrusive interventions like surgical implants and penile injections. Fortunately, sildenafil was introduced to the market and its pill form provides an easy and discreet way to treat ED. From 1998 to 2013, sildenafil was only available under the brand name Viagra. The patent has expired and now the best place to buy generic Viagra online is Sildenafil 4 UK. The generic version of Viagra has the exact same quality and beneficial effects as the branded version. The main difference is that the generic version is available at a much lower price. The reasons for the price difference Manufacturers that produce generic Viagra do not need to invest large amounts of money for research and development. In general, they also spend less on advertising and marketing so they can afford to sell sildenafil at a cheaper price. Furthermore, competition among generic manufacturers helps regulate the price and keep the medication affordable for the consumer. Sildenafil4UK is the best place to buy generic Viagra online because medications are sourced from leading manufacturers in the industry. These pharmaceutical companies produce their sildenafil products in high-quality facilities. They have demonstrated bioequivalence to Viagra as this is a prerequisite for the sale of this medication. As a result, you can expect it to provide the same safety and effects as Viagra. Essential benefits of sildenafil

How does sildenafil work to restore erectile function?

When an erection happens, blood flows into the penis and this is what causes it to become firm. Erectile dysfunction, or ED, happens when there is a problem with blood flow. Various conditions including hypertension, high cholesterol, diabetes and anxiety can cause a disruption in blood flow. Lifestyle choices like physical inactivity, smoking and unhealthy eating habits can also cause ED. An effective PDE5 inhibitor like sildenafil can, however, act against this and restore erectile function. How does sildenafil work in the body? This medication basically works by blocking a natural chemical known as PDE5. This chemical is found in high concentrations in the smooth muscle tissue that lines blood vessels of the penis. PDE5 decreases levels of a molecule called cGMP and, as a result, reduces the body’s ability to produce nitric oxide. Nitric oxide promotes blood vessel dilation and enhanced blood flow. By decreasing levels of PDE5, sildenafil enhances nitric oxide levels and strengthens erections. What is the efficacy rate? Clinical studies have shown that approximately 82 percent of men achieve positive erection results. The strongest effects can be felt within the first four to six hours. How does sildenafil work once it takes it effect is a frequently asked question. A common misconception is that an erection may be present for the entire duration of action. In reality, this medication simply allows the user to achieve a satisfactory erection if sexual stimulation takes place. When will generic Viagra be available?

Sildenafil generic can treat female sexual dysfunction associated with antidepressants

Women who take antidepressants belonging to the selective and nonselective reuptake inhibitor (SRIs) class of medications often report sexual dysfunction. The primary issues are difficulty with arousal and the ability to achieve orgasm. Up to 70 percent of women taking antidepressants report sexual problems. The circumstance can be frustrating but the upside is that sexual side effects can be managed. Can women take sildenafil? The research took place to assess the effect that sildenafil, which is the same as the sildenafil generic would have on women with sexual dysfunction from antidepressant use. The study involved 98 women with an average age of 37 who had normal sexual function before treatment with antidepressants. They were being successfully treated with antidepressants for depression but had considerable sexual dysfunction from their antidepressant medication. Half the patients randomly received 50 – 100mg sildenafil and the other half were given placebo tablets so researchers could compare the difference. The study lasted 8 weeks and the women were told to take a tablet 1 to 2 hours before planned sexual activity. During the study period, 72% of the women treated with the sildenafil generic reported improvements in sexual function. This was compared to only 27% of the women who took inactive placebo pills. The women treated with sildenafil also reported remarkable improvements in terms of satisfaction, enjoyment, and ability to achieve orgasm. This medication increases blood flow and sensitivity in the vaginal region. This, in turn, results in improved natural lubrication and overall satisfaction during sexual intercourse. The durational efficacy is four to six hours which allows enough time for sex without feeling rushed. 5 tips for safe and effective use

Sildenafil UK licensed tablets can treat ED associated with CAD

Coronary artery disease (CAD) is a common condition that is characterised by hardening of the arteries. When a patient has CAD, cholesterol and other substances accumulate on the walls of blood vessels. This can cause them to become narrower which makes it harder for blood to flow through them and reach the penis. Healthy blood supply is essential for erections as this is what gives the penis rigidity. Reduced blood flow is by far the most common cause of erectile dysfunction (ED). Sildenafil UK approved tablets can, however, effectively treat this condition by improving blood flow. This medicine is a PDE5 inhibitor that works in response to sexual stimulation. Understanding how it functions in the body Phosphodiesterase 5, or PDE5, is a naturally-occurring enzyme that regulates blood flow. It is found in various tissues including blood vessels of the penis. PDE5 causes levels of another enzyme called cGMP to decrease, thereby reducing the body’s ability to produce nitric oxide. Nitric oxide causes blood vessels to dilate which enhances blood flow to the penis. By blocking PDE5, sildenafil UK certified tabletsboostlevels of nitric oxidewhich restores erectile function. The unplanned discovery of Viagra The discovery that this medicine can improve erectile function was an unplanned event. Sildenafil was originally developed to treat heart conditions like high blood pressure and angina. During early clinical studies in the 1990’s, patients were given varying doses of the medicine to test its efficacy for treating heart conditions. Interestingly, erections were noted as a side effect. The researchers realised that sildenafil could provide an excellent on-demand treatment for ED.